Click here to switch to the map view.

The map label for this gene is rpe [H]

Identifier: 169824366

GI number: 169824366

Start: 733644

End: 734300

Strand: Direct

Name: rpe [H]

Synonym: FMG_0669

Alternate gene names: 169824366

Gene position: 733644-734300 (Clockwise)

Preceding gene: 169824365

Following gene: 169824367

Centisome position: 40.81

GC content: 28.16

Gene sequence:

>657_bases
ATGGCTAGTTTGAGTCCGTCTTTGTTGGCGTGTAATTTTTTTGAATTAGAAAAGAACTTAGATATATTAAAAAATAAAGG
AATAAGATATTTACATTTAGATGTTATGGATGGAAATTTTGTACCAAATATTTCTTTTGGACCAGCAATTATAAAACAAA
TCAGAGAAAAATATCCAGAATTTATCTTTGATTGTCACCTTATGGTTAATAAACCAGAGAATGTTATAAATGATATATTG
GATGCAGGAGCTGATATAATTACTTTTCACCCAGAAGCAACTTTTCATCCTCATAGAATAATTCAAACTGTTCATAAAGC
AGGTAAAAAGTGTGGGTTAGCATTAAATCCTTCTACAGGGTTAGAATCTTGTAAATATATTATTGATGATTTAGATATTA
TACTTGTAATGAGCGTAAATCCAGGTTTTGGGGGACAATCGTTCATAGAAAGTCAATATTTGAAATTAATAGACGCAAGA
AATATGATAAAAGCTTCAAAAAAAGATATTATATTAGAAGTTGATGGAGGAGTTAAAACTTCGAATATTGATAAAGTTTT
GGAGTCAGGAGCTGATTTAATCGTAAGTGGATCAGATGTTTTCAATCATAATATTGAATCACAATTAGATATTTATAATC
AAAAATTAAAAAGATAG

Upstream 100 bases:

>100_bases
GCGAAATAAAAAAACTTTTAGAATCTGGAGAAATATCTAAAAGTAGATATGATAACTATTTAAAAATTGTAGAAGAATAC
GAGAAAATTAGGAGGTATTA

Downstream 100 bases:

>100_bases
GGAGAATGTTATGAACAAAAATTTGAAGTTTATGGTTGAAGGAGCTATTACTTTAGCTCTTACAGCGGTATTGAACAGTA
TAGTAATTTTTAAAATGCCA

Product: ribulose-phosphate 3-epimerase

Products: NA

Alternate protein names: Pentose-5-phosphate 3-epimerase; PPE; R5P3E [H]

Number of amino acids: Translated: 218; Mature: 217

Protein sequence:

>218_residues
MASLSPSLLACNFFELEKNLDILKNKGIRYLHLDVMDGNFVPNISFGPAIIKQIREKYPEFIFDCHLMVNKPENVINDIL
DAGADIITFHPEATFHPHRIIQTVHKAGKKCGLALNPSTGLESCKYIIDDLDIILVMSVNPGFGGQSFIESQYLKLIDAR
NMIKASKKDIILEVDGGVKTSNIDKVLESGADLIVSGSDVFNHNIESQLDIYNQKLKR

Sequences:

>Translated_218_residues
MASLSPSLLACNFFELEKNLDILKNKGIRYLHLDVMDGNFVPNISFGPAIIKQIREKYPEFIFDCHLMVNKPENVINDIL
DAGADIITFHPEATFHPHRIIQTVHKAGKKCGLALNPSTGLESCKYIIDDLDIILVMSVNPGFGGQSFIESQYLKLIDAR
NMIKASKKDIILEVDGGVKTSNIDKVLESGADLIVSGSDVFNHNIESQLDIYNQKLKR
>Mature_217_residues
ASLSPSLLACNFFELEKNLDILKNKGIRYLHLDVMDGNFVPNISFGPAIIKQIREKYPEFIFDCHLMVNKPENVINDILD
AGADIITFHPEATFHPHRIIQTVHKAGKKCGLALNPSTGLESCKYIIDDLDIILVMSVNPGFGGQSFIESQYLKLIDARN
MIKASKKDIILEVDGGVKTSNIDKVLESGADLIVSGSDVFNHNIESQLDIYNQKLKR

Specific function: Unknown

COG id: COG0036

COG function: function code G; Pentose-5-phosphate-3-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribulose-phosphate 3-epimerase family [H]

Homologues:

Organism=Homo sapiens, GI40385883, Length=200, Percent_Identity=39, Blast_Score=148, Evalue=3e-36,
Organism=Homo sapiens, GI219879828, Length=199, Percent_Identity=37.1859296482412, Blast_Score=139, Evalue=2e-33,
Organism=Homo sapiens, GI24307923, Length=155, Percent_Identity=35.4838709677419, Blast_Score=96, Evalue=3e-20,
Organism=Escherichia coli, GI1789788, Length=200, Percent_Identity=44.5, Blast_Score=177, Evalue=5e-46,
Organism=Escherichia coli, GI1790523, Length=217, Percent_Identity=35.4838709677419, Blast_Score=144, Evalue=4e-36,
Organism=Escherichia coli, GI1790754, Length=199, Percent_Identity=27.1356783919598, Blast_Score=91, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI17552948, Length=199, Percent_Identity=37.1859296482412, Blast_Score=134, Evalue=3e-32,
Organism=Saccharomyces cerevisiae, GI6322341, Length=211, Percent_Identity=37.4407582938389, Blast_Score=148, Evalue=6e-37,
Organism=Drosophila melanogaster, GI24586301, Length=208, Percent_Identity=37.9807692307692, Blast_Score=150, Evalue=4e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR000056
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00834 Ribul_P_3_epim [H]

EC number: =5.1.3.1 [H]

Molecular weight: Translated: 24314; Mature: 24183

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: PS01085 RIBUL_P_3_EPIMER_1 ; PS01086 RIBUL_P_3_EPIMER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASLSPSLLACNFFELEKNLDILKNKGIRYLHLDVMDGNFVPNISFGPAIIKQIREKYPE
CCCCCCHHHHHHHHHHHCCHHHHHCCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHCHH
FIFDCHLMVNKPENVINDILDAGADIITFHPEATFHPHRIIQTVHKAGKKCGLALNPSTG
HHEEEHEEECCCHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHHCCEEECCCCC
LESCKYIIDDLDIILVMSVNPGFGGQSFIESQYLKLIDARNMIKASKKDIILEVDGGVKT
HHHHHHHHCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCC
SNIDKVLESGADLIVSGSDVFNHNIESQLDIYNQKLKR
HHHHHHHHCCCCEEEECCHHHCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
ASLSPSLLACNFFELEKNLDILKNKGIRYLHLDVMDGNFVPNISFGPAIIKQIREKYPE
CCCCCHHHHHHHHHHHCCHHHHHCCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHCHH
FIFDCHLMVNKPENVINDILDAGADIITFHPEATFHPHRIIQTVHKAGKKCGLALNPSTG
HHEEEHEEECCCHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHHCCEEECCCCC
LESCKYIIDDLDIILVMSVNPGFGGQSFIESQYLKLIDARNMIKASKKDIILEVDGGVKT
HHHHHHHHCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCC
SNIDKVLESGADLIVSGSDVFNHNIESQLDIYNQKLKR
HHHHHHHHCCCCEEEECCHHHCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]