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The map label for this gene is rnr [H]

Identifier: 169824349

GI number: 169824349

Start: 715742

End: 717847

Strand: Direct

Name: rnr [H]

Synonym: FMG_0652

Alternate gene names: 169824349

Gene position: 715742-717847 (Clockwise)

Preceding gene: 169824348

Following gene: 169824350

Centisome position: 39.82

GC content: 29.91

Gene sequence:

>2106_bases
ATGAAAATAAAGCAAAAGGTACTTAATATCGTAAATTCTAATGATTATATCCCTTTAACTTTTGATGAATTATCTTCACG
ATTAAATATTGAAAAAAAAGATAAAAAAATTTTTCATAAGATTATTAATGAACTACAAAAAGATAAAAAAATTTTACTTG
ATAAAAATTCTAATATAATTCCAATTACAGAGCAAAAAGCATATCCAGGAACTATTCAAGGATCTGGAAGTGATTTTTGC
TATTTTATTCCTGATGATGAAAATGTTGACGATATTTTTATAGCAAAAAAAGATTTAAATGGTGCAATTCACAAAGACAA
GGTTTTAGTTACAATAACAGTAGAAAAAAAGCCTAACCGTAGTCCTGAAGGTAAAGTTTTACAAATTTTATCCAGAGAAA
CGAAAAAACTTGTTGGAACTTTTGATGAGGCAAAAGGTTATGGATTTGTAATTTTGGATGATAAAAAATACGGATTCGAT
GTTTTTGTCCAATCTGGTAACAAAAATGGAGCAAAAAATAACGATAAAGTAGTGGTAAAATTAATCAAAACTCCATCCAA
AAATCACAAAAATCCAGAAGGAGTGATAGTTGAGGTTTTAGGTGGCAAGGACGACCCAGGAATTGATATTTATTCTATAG
CAAAGACTTTTAAATTACCTTATGAATTTCCAAAGAAAGTAAAACAACAAGCAAAAGAGATAGAACAGCATGTTGATGAA
TCAGAAAAAAAATCTAGAATGGATTTTAGAGATTTGCTTACTGTTTCAATAGATGGATCTGATGCAAAAGATTTTGATGA
CGCAATAAGTATCACAAAAAAAGGAGAAAACTTTGTACTATATGTTCATATAGCTGATGTCAGCCATTATGTGAAAAAGA
ACACTGCACTAGACAAGGAAGCTTTTAGAAGAGGAACAAGTGTATATATGTTAGACAGGGTAATTCCAATGTTGCCTGTG
GAACTATCTAATGGAATTTGTTCACTAAATCCAAATGAAGACAGACTTTGCTTAACAATTAAAATGGAAATTTCGCCAAC
TGGGAAAACTCTTGACTATAAATTTTACGAGTCGGTGATTAATTCTGACTATAGATTAATCTACAAAAATGTGTCAGACT
TTTTGGAAGACATAGATAATCCTTATGAAGATGAAAAACTCACGGACAATTTACTATTAATGAAAGAATTGTATGAAATT
CTAAGTGCTAGAAGAAAAAAGAGAGGTAGCATTGACTTCGACTTTCCAGAAACTAAAATTATTTTAGATGAAAATTCTAA
AGTAATAGATGTTACAAAGGATGAGAGAAGAATTGGAAATAAGTTGATTGAAGAATTCATGTTGATTACCAATGAAACTG
TAGCAAGCCATTTTGGATATTTGGATAGACCGTTTTTATACAGAGTTCATGAAGAACCTGACGAAGAAAAAGTTAATACT
TTTAAAAGAATTTTGTCAAACTTTGGATATCACTTAAAAGGTAAGAATTTGTACTCTAAAGATTACCAAAGAATTTTGAA
TGAACTAGATGGTAAGCCTGAAAAACCTCTGCTTGCTTCACTTTTGTTAAGATCTATGCAAAAGGCTGAATATAGCGAAA
ATCCTAGCATTCATTTCGGATTAGCATCTATGTTCTATACGCATTTCACATCTCCAATTAGAAGATACCCGGATTTATTT
ATTCACAGAATTGTAAAGAATTTTATAAACCATAAACCAGATACTAATAATGAAAAAGAGTTCATGAAATACATCAAAGA
CATCGCGAAGCAATGTTCAGCAACTGAAAGAAGAGCAGAAGAAGCTGAAAGAGAAGCTATTGATATGAAATCAGCAGAAT
ATATGCAGCAACACATAGATGAGGAATTTGAGGGAATTATTAGTTCACTTACGAAATTTGGAATCTTCGTACAACTTGAC
AATACTATTGAAGGTTTAGTACAATTTCAATCTATGATAGATGATTATTATGTATTTGACGAAAAAAACTACACGGTTTA
TGGAGAAAGAACAAAAAAATCATATCATATTGGACAAAAAGTTAGAGTTAAAGTTATAAATAGCGATAAAGACAAGCGTC
AAATAGATTTTGAATTTGTAAATTAG

Upstream 100 bases:

>100_bases
GATAAGGGAAGAATTATAAAATAAGCATTAAATACAATAATTAGGTAGTTTTTTGTCATTTAGGGTATAATATAGATAGG
AAACAAACAGGAGGTATTTA

Downstream 100 bases:

>100_bases
AAAAGGAATATAATGAGTGAAATAAAATTATTAGCTAACAATAAAAAAGCACGCCACGAGTATTTTATTGAAGAAGTGTA
CGAATGTGGAATTGAATTAA

Product: exoribonuclease

Products: NA

Alternate protein names: RNase R; VacB protein homolog [H]

Number of amino acids: Translated: 701; Mature: 701

Protein sequence:

>701_residues
MKIKQKVLNIVNSNDYIPLTFDELSSRLNIEKKDKKIFHKIINELQKDKKILLDKNSNIIPITEQKAYPGTIQGSGSDFC
YFIPDDENVDDIFIAKKDLNGAIHKDKVLVTITVEKKPNRSPEGKVLQILSRETKKLVGTFDEAKGYGFVILDDKKYGFD
VFVQSGNKNGAKNNDKVVVKLIKTPSKNHKNPEGVIVEVLGGKDDPGIDIYSIAKTFKLPYEFPKKVKQQAKEIEQHVDE
SEKKSRMDFRDLLTVSIDGSDAKDFDDAISITKKGENFVLYVHIADVSHYVKKNTALDKEAFRRGTSVYMLDRVIPMLPV
ELSNGICSLNPNEDRLCLTIKMEISPTGKTLDYKFYESVINSDYRLIYKNVSDFLEDIDNPYEDEKLTDNLLLMKELYEI
LSARRKKRGSIDFDFPETKIILDENSKVIDVTKDERRIGNKLIEEFMLITNETVASHFGYLDRPFLYRVHEEPDEEKVNT
FKRILSNFGYHLKGKNLYSKDYQRILNELDGKPEKPLLASLLLRSMQKAEYSENPSIHFGLASMFYTHFTSPIRRYPDLF
IHRIVKNFINHKPDTNNEKEFMKYIKDIAKQCSATERRAEEAEREAIDMKSAEYMQQHIDEEFEGIISSLTKFGIFVQLD
NTIEGLVQFQSMIDDYYVFDEKNYTVYGERTKKSYHIGQKVRVKVINSDKDKRQIDFEFVN

Sequences:

>Translated_701_residues
MKIKQKVLNIVNSNDYIPLTFDELSSRLNIEKKDKKIFHKIINELQKDKKILLDKNSNIIPITEQKAYPGTIQGSGSDFC
YFIPDDENVDDIFIAKKDLNGAIHKDKVLVTITVEKKPNRSPEGKVLQILSRETKKLVGTFDEAKGYGFVILDDKKYGFD
VFVQSGNKNGAKNNDKVVVKLIKTPSKNHKNPEGVIVEVLGGKDDPGIDIYSIAKTFKLPYEFPKKVKQQAKEIEQHVDE
SEKKSRMDFRDLLTVSIDGSDAKDFDDAISITKKGENFVLYVHIADVSHYVKKNTALDKEAFRRGTSVYMLDRVIPMLPV
ELSNGICSLNPNEDRLCLTIKMEISPTGKTLDYKFYESVINSDYRLIYKNVSDFLEDIDNPYEDEKLTDNLLLMKELYEI
LSARRKKRGSIDFDFPETKIILDENSKVIDVTKDERRIGNKLIEEFMLITNETVASHFGYLDRPFLYRVHEEPDEEKVNT
FKRILSNFGYHLKGKNLYSKDYQRILNELDGKPEKPLLASLLLRSMQKAEYSENPSIHFGLASMFYTHFTSPIRRYPDLF
IHRIVKNFINHKPDTNNEKEFMKYIKDIAKQCSATERRAEEAEREAIDMKSAEYMQQHIDEEFEGIISSLTKFGIFVQLD
NTIEGLVQFQSMIDDYYVFDEKNYTVYGERTKKSYHIGQKVRVKVINSDKDKRQIDFEFVN
>Mature_701_residues
MKIKQKVLNIVNSNDYIPLTFDELSSRLNIEKKDKKIFHKIINELQKDKKILLDKNSNIIPITEQKAYPGTIQGSGSDFC
YFIPDDENVDDIFIAKKDLNGAIHKDKVLVTITVEKKPNRSPEGKVLQILSRETKKLVGTFDEAKGYGFVILDDKKYGFD
VFVQSGNKNGAKNNDKVVVKLIKTPSKNHKNPEGVIVEVLGGKDDPGIDIYSIAKTFKLPYEFPKKVKQQAKEIEQHVDE
SEKKSRMDFRDLLTVSIDGSDAKDFDDAISITKKGENFVLYVHIADVSHYVKKNTALDKEAFRRGTSVYMLDRVIPMLPV
ELSNGICSLNPNEDRLCLTIKMEISPTGKTLDYKFYESVINSDYRLIYKNVSDFLEDIDNPYEDEKLTDNLLLMKELYEI
LSARRKKRGSIDFDFPETKIILDENSKVIDVTKDERRIGNKLIEEFMLITNETVASHFGYLDRPFLYRVHEEPDEEKVNT
FKRILSNFGYHLKGKNLYSKDYQRILNELDGKPEKPLLASLLLRSMQKAEYSENPSIHFGLASMFYTHFTSPIRRYPDLF
IHRIVKNFINHKPDTNNEKEFMKYIKDIAKQCSATERRAEEAEREAIDMKSAEYMQQHIDEEFEGIISSLTKFGIFVQLD
NTIEGLVQFQSMIDDYYVFDEKNYTVYGERTKKSYHIGQKVRVKVINSDKDKRQIDFEFVN

Specific function: 3'-5'exoribonuclease that participates in an essential cell function. Acts nonspecifically on poly(A), poly(U) and ribosomal RNAs [H]

COG id: COG0557

COG function: function code K; Exoribonuclease R

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1 motif domain [H]

Homologues:

Organism=Homo sapiens, GI190014625, Length=593, Percent_Identity=27.8246205733558, Blast_Score=189, Evalue=6e-48,
Organism=Homo sapiens, GI190014623, Length=593, Percent_Identity=27.8246205733558, Blast_Score=189, Evalue=8e-48,
Organism=Homo sapiens, GI134288890, Length=362, Percent_Identity=30.6629834254144, Blast_Score=157, Evalue=5e-38,
Organism=Homo sapiens, GI219521928, Length=574, Percent_Identity=26.3066202090592, Blast_Score=146, Evalue=6e-35,
Organism=Homo sapiens, GI19115966, Length=574, Percent_Identity=26.3066202090592, Blast_Score=146, Evalue=8e-35,
Organism=Homo sapiens, GI156105695, Length=190, Percent_Identity=29.4736842105263, Blast_Score=88, Evalue=3e-17,
Organism=Homo sapiens, GI156105693, Length=190, Percent_Identity=29.4736842105263, Blast_Score=84, Evalue=4e-16,
Organism=Escherichia coli, GI87082383, Length=719, Percent_Identity=35.4659248956885, Blast_Score=453, Evalue=1e-128,
Organism=Escherichia coli, GI1787542, Length=616, Percent_Identity=26.9480519480519, Blast_Score=179, Evalue=5e-46,
Organism=Caenorhabditis elegans, GI17553506, Length=411, Percent_Identity=31.3868613138686, Blast_Score=184, Evalue=2e-46,
Organism=Caenorhabditis elegans, GI212645896, Length=408, Percent_Identity=30.6372549019608, Blast_Score=177, Evalue=1e-44,
Organism=Saccharomyces cerevisiae, GI6324552, Length=592, Percent_Identity=28.8851351351351, Blast_Score=185, Evalue=2e-47,
Organism=Saccharomyces cerevisiae, GI6320499, Length=479, Percent_Identity=25.0521920668058, Blast_Score=92, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24649634, Length=475, Percent_Identity=28, Blast_Score=175, Evalue=1e-43,
Organism=Drosophila melanogaster, GI24654592, Length=467, Percent_Identity=27.8372591006424, Blast_Score=155, Evalue=7e-38,
Organism=Drosophila melanogaster, GI19922976, Length=467, Percent_Identity=27.8372591006424, Blast_Score=155, Evalue=7e-38,
Organism=Drosophila melanogaster, GI24654597, Length=467, Percent_Identity=27.8372591006424, Blast_Score=155, Evalue=7e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011129
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR003029
- InterPro:   IPR022967
- InterPro:   IPR013223
- InterPro:   IPR001900
- InterPro:   IPR022966
- InterPro:   IPR004476
- InterPro:   IPR011805 [H]

Pfam domain/function: PF08206 OB_RNB; PF00773 RNB; PF00575 S1 [H]

EC number: 3.1.-.- [C]

Molecular weight: Translated: 81268; Mature: 81268

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: PS50126 S1 ; PS01175 RIBONUCLEASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIKQKVLNIVNSNDYIPLTFDELSSRLNIEKKDKKIFHKIINELQKDKKILLDKNSNII
CCHHHHHHHHHCCCCEEEEEHHHHHHHCCCCHHHHHHHHHHHHHHHHCCEEEEECCCCEE
PITEQKAYPGTIQGSGSDFCYFIPDDENVDDIFIAKKDLNGAIHKDKVLVTITVEKKPNR
EEECCCCCCCCEECCCCCEEEECCCCCCCCEEEEEEECCCCCEECCCEEEEEEEECCCCC
SPEGKVLQILSRETKKLVGTFDEAKGYGFVILDDKKYGFDVFVQSGNKNGAKNNDKVVVK
CCCHHHHHHHHHHHHHHHCCHHHCCCCEEEEECCCCCCEEEEEECCCCCCCCCCCEEEEE
LIKTPSKNHKNPEGVIVEVLGGKDDPGIDIYSIAKTFKLPYEFPKKVKQQAKEIEQHVDE
EEECCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCH
SEKKSRMDFRDLLTVSIDGSDAKDFDDAISITKKGENFVLYVHIADVSHYVKKNTALDKE
HHHHHHCCHHHEEEEEECCCCCCCHHHHHHHEECCCCEEEEEEEECHHHHHHHCCCCCHH
AFRRGTSVYMLDRVIPMLPVELSNGICSLNPNEDRLCLTIKMEISPTGKTLDYKFYESVI
HHHCCCCEEEHHHHHHHCCHHHCCCEEECCCCCCEEEEEEEEEECCCCCEECHHHHHHHH
NSDYRLIYKNVSDFLEDIDNPYEDEKLTDNLLLMKELYEILSARRKKRGSIDFDFPETKI
CCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEE
ILDENSKVIDVTKDERRIGNKLIEEFMLITNETVASHFGYLDRPFLYRVHEEPDEEKVNT
EEECCCCEEEECHHHHHHHHHHHHHHHHHHCHHHHHHCCCCCCCEEEEECCCCCHHHHHH
FKRILSNFGYHLKGKNLYSKDYQRILNELDGKPEKPLLASLLLRSMQKAEYSENPSIHFG
HHHHHHHCCCEECCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEH
LASMFYTHFTSPIRRYPDLFIHRIVKNFINHKPDTNNEKEFMKYIKDIAKQCSATERRAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
EAEREAIDMKSAEYMQQHIDEEFEGIISSLTKFGIFVQLDNTIEGLVQFQSMIDDYYVFD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECHHHHHHHHHHHHHHHEEEEE
EKNYTVYGERTKKSYHIGQKVRVKVINSDKDKRQIDFEFVN
CCCEEEEECCCCCCCCCCCEEEEEEECCCCCCEEEEEEECC
>Mature Secondary Structure
MKIKQKVLNIVNSNDYIPLTFDELSSRLNIEKKDKKIFHKIINELQKDKKILLDKNSNII
CCHHHHHHHHHCCCCEEEEEHHHHHHHCCCCHHHHHHHHHHHHHHHHCCEEEEECCCCEE
PITEQKAYPGTIQGSGSDFCYFIPDDENVDDIFIAKKDLNGAIHKDKVLVTITVEKKPNR
EEECCCCCCCCEECCCCCEEEECCCCCCCCEEEEEEECCCCCEECCCEEEEEEEECCCCC
SPEGKVLQILSRETKKLVGTFDEAKGYGFVILDDKKYGFDVFVQSGNKNGAKNNDKVVVK
CCCHHHHHHHHHHHHHHHCCHHHCCCCEEEEECCCCCCEEEEEECCCCCCCCCCCEEEEE
LIKTPSKNHKNPEGVIVEVLGGKDDPGIDIYSIAKTFKLPYEFPKKVKQQAKEIEQHVDE
EEECCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCH
SEKKSRMDFRDLLTVSIDGSDAKDFDDAISITKKGENFVLYVHIADVSHYVKKNTALDKE
HHHHHHCCHHHEEEEEECCCCCCCHHHHHHHEECCCCEEEEEEEECHHHHHHHCCCCCHH
AFRRGTSVYMLDRVIPMLPVELSNGICSLNPNEDRLCLTIKMEISPTGKTLDYKFYESVI
HHHCCCCEEEHHHHHHHCCHHHCCCEEECCCCCCEEEEEEEEEECCCCCEECHHHHHHHH
NSDYRLIYKNVSDFLEDIDNPYEDEKLTDNLLLMKELYEILSARRKKRGSIDFDFPETKI
CCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEE
ILDENSKVIDVTKDERRIGNKLIEEFMLITNETVASHFGYLDRPFLYRVHEEPDEEKVNT
EEECCCCEEEECHHHHHHHHHHHHHHHHHHCHHHHHHCCCCCCCEEEEECCCCCHHHHHH
FKRILSNFGYHLKGKNLYSKDYQRILNELDGKPEKPLLASLLLRSMQKAEYSENPSIHFG
HHHHHHHCCCEECCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEH
LASMFYTHFTSPIRRYPDLFIHRIVKNFINHKPDTNNEKEFMKYIKDIAKQCSATERRAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
EAEREAIDMKSAEYMQQHIDEEFEGIISSLTKFGIFVQLDNTIEGLVQFQSMIDDYYVFD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECHHHHHHHHHHHHHHHEEEEE
EKNYTVYGERTKKSYHIGQKVRVKVINSDKDKRQIDFEFVN
CCCEEEEECCCCCCCCCCCEEEEEEECCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]