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The map label for this gene is pepD [H]

Identifier: 169823910

GI number: 169823910

Start: 251307

End: 252722

Strand: Direct

Name: pepD [H]

Synonym: FMG_0213

Alternate gene names: 169823910

Gene position: 251307-252722 (Clockwise)

Preceding gene: 169823909

Following gene: 169823921

Centisome position: 13.98

GC content: 35.81

Gene sequence:

>1416_bases
ATGTTAGAAAATTTAAAACCGGAAAGAGTGTTTCATTATTTCGAAGAATTGACTAAAATTCCAAGAGAATCTGGAAATGA
ACAGGCAGTTAGTGATTTCTTGTACAAGACTGGAAAAGAATTGGGACTTGAAACTATACAAGACGAAAGTAACAACGTTA
TAATCAGAAAACCAGCTCATCCAGATTATGTGGATCATCCTGCTGTTGTAATTCAAGGTCACATGGATATGGTCGCAGAA
AAAGCTGATGGAGTTGATCACGACTTTTTGACAGATCCTATTCCTCTTGTTGTAGACGGCGATTGGGTTAAAACAGAAGG
CACTACTTTGGGTGCAGATGATGGTATTGCAAGTGCTATTGGACTTGCAATCATGGAAGACAAAAACGGTAAGCACCCTG
CACTTGAATTATTGGTTACAACTAATGAAGAAACTACAATGGTCGGAGCAAGGGCATTGAAGAGAGAAAACATCAAAGGA
AGAAAACTTTTGAATATTGACGCTGAAGTAGAAGGAATTTTGTTGTCTGGTTGTTCAGGTGGACACAACATAATAGGAAC
TAAAAAGTTAAATTATGTGGATAATAAAATGAAAAATACTTTTGTAATGAATATTAACAACATGCTCGGTGGTCACTCAG
GAATGGAAATTCACCAACAAAGAGGTAACTCCATCAAATTTGCACGTGAAGCTTTGAAGTTAATCGAAGAAAAATCACCT
GTAGAAATTGTTAGTATAGAAGGTGGAACAAAACACAATGCTATTCCAAGAGATGCGAAAGTTGTGTTCAGTTCAAATGA
AGACGACTACGATATTGATTTTTCTGATTTAATTGCAAAATATCCATTGGATAAGGATATGAGAGTTAAAATCGAAAAAT
GTGAAAACGCAGATAAAGTATTGGATGAAAAAAATAAGGAAGATATCTTATCTTTCATCGAAGAGGTTCCTCACGGAGTT
TACAGCATGATGCAAGAATACCCAGATATCGTTGAATGCTCCAACAACTTGGCTATTTTCGAAATAAAAGATGATGTGTT
GAAGGTAACCATTTCTCTTAGAAGTTCAAACCCAGAAACATTTGATGCACATACTGAAGATGTGTCAAAAGTTTATGAAA
AATACGGATTTGAAGTTAAGAAGGAAGATTATTACAAACCATGGGCATTTGCAAAAGATTCTGAATTGAGAAACTTGGCG
CTTGAAACATACAAAGATTTGTTTGGAAAAGAAATGAAGGTTGAAGTTGTTCACGCAGCATTGGAGCCAGCAGTGTTTAT
CGACACATTCCCAGACATGGAAATGATCTCCATAGGACCTACTATGAAAGACGTTCACAGTCCTAAGGAAAGACTTTCAA
TAGAATCAACACAAAGAACTTACGAATTTGTGAAATCACTTCTAGAAAGACTTTAG

Upstream 100 bases:

>100_bases
AATATTGTTACATTAATTTAGAAATTTGAACACATTCTTTGGGTTAATCTCAAAGAATGTGTTTGTTTGAACAGTAATTT
GAACAGAAAAAGGAGAAAAT

Downstream 100 bases:

>100_bases
TTTTTGACAAAATAAATCACAGAGAAAAACTGTGATAGACAAACCCTTATGCATAGTAATCGACGATTTTGTTGTCGTGT
GCATAAGGGTTTTTTTGTTT

Product: aminoacyl-histidine dipeptidase

Products: NA

Alternate protein names: Beta-alanyl-histidine dipeptidase; Carnosinase; Peptidase D; Xaa-His dipeptidase; X-His dipeptidase [H]

Number of amino acids: Translated: 471; Mature: 471

Protein sequence:

>471_residues
MLENLKPERVFHYFEELTKIPRESGNEQAVSDFLYKTGKELGLETIQDESNNVIIRKPAHPDYVDHPAVVIQGHMDMVAE
KADGVDHDFLTDPIPLVVDGDWVKTEGTTLGADDGIASAIGLAIMEDKNGKHPALELLVTTNEETTMVGARALKRENIKG
RKLLNIDAEVEGILLSGCSGGHNIIGTKKLNYVDNKMKNTFVMNINNMLGGHSGMEIHQQRGNSIKFAREALKLIEEKSP
VEIVSIEGGTKHNAIPRDAKVVFSSNEDDYDIDFSDLIAKYPLDKDMRVKIEKCENADKVLDEKNKEDILSFIEEVPHGV
YSMMQEYPDIVECSNNLAIFEIKDDVLKVTISLRSSNPETFDAHTEDVSKVYEKYGFEVKKEDYYKPWAFAKDSELRNLA
LETYKDLFGKEMKVEVVHAALEPAVFIDTFPDMEMISIGPTMKDVHSPKERLSIESTQRTYEFVKSLLERL

Sequences:

>Translated_471_residues
MLENLKPERVFHYFEELTKIPRESGNEQAVSDFLYKTGKELGLETIQDESNNVIIRKPAHPDYVDHPAVVIQGHMDMVAE
KADGVDHDFLTDPIPLVVDGDWVKTEGTTLGADDGIASAIGLAIMEDKNGKHPALELLVTTNEETTMVGARALKRENIKG
RKLLNIDAEVEGILLSGCSGGHNIIGTKKLNYVDNKMKNTFVMNINNMLGGHSGMEIHQQRGNSIKFAREALKLIEEKSP
VEIVSIEGGTKHNAIPRDAKVVFSSNEDDYDIDFSDLIAKYPLDKDMRVKIEKCENADKVLDEKNKEDILSFIEEVPHGV
YSMMQEYPDIVECSNNLAIFEIKDDVLKVTISLRSSNPETFDAHTEDVSKVYEKYGFEVKKEDYYKPWAFAKDSELRNLA
LETYKDLFGKEMKVEVVHAALEPAVFIDTFPDMEMISIGPTMKDVHSPKERLSIESTQRTYEFVKSLLERL
>Mature_471_residues
MLENLKPERVFHYFEELTKIPRESGNEQAVSDFLYKTGKELGLETIQDESNNVIIRKPAHPDYVDHPAVVIQGHMDMVAE
KADGVDHDFLTDPIPLVVDGDWVKTEGTTLGADDGIASAIGLAIMEDKNGKHPALELLVTTNEETTMVGARALKRENIKG
RKLLNIDAEVEGILLSGCSGGHNIIGTKKLNYVDNKMKNTFVMNINNMLGGHSGMEIHQQRGNSIKFAREALKLIEEKSP
VEIVSIEGGTKHNAIPRDAKVVFSSNEDDYDIDFSDLIAKYPLDKDMRVKIEKCENADKVLDEKNKEDILSFIEEVPHGV
YSMMQEYPDIVECSNNLAIFEIKDDVLKVTISLRSSNPETFDAHTEDVSKVYEKYGFEVKKEDYYKPWAFAKDSELRNLA
LETYKDLFGKEMKVEVVHAALEPAVFIDTFPDMEMISIGPTMKDVHSPKERLSIESTQRTYEFVKSLLERL

Specific function: Dipeptidase with broad substrate specificity [H]

COG id: COG2195

COG function: function code E; Di- and tripeptidases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20C family [H]

Homologues:

Organism=Escherichia coli, GI1786432, Length=480, Percent_Identity=31.0416666666667, Blast_Score=253, Evalue=3e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002933
- InterPro:   IPR011650
- InterPro:   IPR001160 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.4.13.3 [H]

Molecular weight: Translated: 53134; Mature: 53134

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLENLKPERVFHYFEELTKIPRESGNEQAVSDFLYKTGKELGLETIQDESNNVIIRKPAH
CCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCHHHCCCCCCEEEECCCC
PDYVDHPAVVIQGHMDMVAEKADGVDHDFLTDPIPLVVDGDWVKTEGTTLGADDGIASAI
CCCCCCCEEEEECHHHHHHHHCCCCCCCCCCCCCCEEECCCEEEECCCCCCCCCCHHHHH
GLAIMEDKNGKHPALELLVTTNEETTMVGARALKRENIKGRKLLNIDAEVEGILLSGCSG
CEEEEECCCCCCCEEEEEEECCCCHHHHHHHHHHHCCCCCCEEEEECCCCCEEEEECCCC
GHNIIGTKKLNYVDNKMKNTFVMNINNMLGGHSGMEIHQQRGNSIKFAREALKLIEEKSP
CCCCCCCCCCHHHHHHHCCEEEEEEHHHHCCCCCCHHHHHCCCCHHHHHHHHHHHCCCCC
VEIVSIEGGTKHNAIPRDAKVVFSSNEDDYDIDFSDLIAKYPLDKDMRVKIEKCENADKV
EEEEEECCCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHCCCCCCCEEEEHHHCCHHHH
LDEKNKEDILSFIEEVPHGVYSMMQEYPDIVECSNNLAIFEIKDDVLKVTISLRSSNPET
HCCCCHHHHHHHHHHCCHHHHHHHHHCCCHHHCCCCEEEEEECCCEEEEEEEEECCCCCC
FDAHTEDVSKVYEKYGFEVKKEDYYKPWAFAKDSELRNLALETYKDLFGKEMKVEVVHAA
CCCCHHHHHHHHHHHCCEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHH
LEPAVFIDTFPDMEMISIGPTMKDVHSPKERLSIESTQRTYEFVKSLLERL
HCCEEEEECCCCCEEEECCCCHHHHCCHHHHHCHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MLENLKPERVFHYFEELTKIPRESGNEQAVSDFLYKTGKELGLETIQDESNNVIIRKPAH
CCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCHHHCCCCCCEEEECCCC
PDYVDHPAVVIQGHMDMVAEKADGVDHDFLTDPIPLVVDGDWVKTEGTTLGADDGIASAI
CCCCCCCEEEEECHHHHHHHHCCCCCCCCCCCCCCEEECCCEEEECCCCCCCCCCHHHHH
GLAIMEDKNGKHPALELLVTTNEETTMVGARALKRENIKGRKLLNIDAEVEGILLSGCSG
CEEEEECCCCCCCEEEEEEECCCCHHHHHHHHHHHCCCCCCEEEEECCCCCEEEEECCCC
GHNIIGTKKLNYVDNKMKNTFVMNINNMLGGHSGMEIHQQRGNSIKFAREALKLIEEKSP
CCCCCCCCCCHHHHHHHCCEEEEEEHHHHCCCCCCHHHHHCCCCHHHHHHHHHHHCCCCC
VEIVSIEGGTKHNAIPRDAKVVFSSNEDDYDIDFSDLIAKYPLDKDMRVKIEKCENADKV
EEEEEECCCCCCCCCCCCCEEEEECCCCCCCCCHHHHHHHCCCCCCCEEEEHHHCCHHHH
LDEKNKEDILSFIEEVPHGVYSMMQEYPDIVECSNNLAIFEIKDDVLKVTISLRSSNPET
HCCCCHHHHHHHHHHCCHHHHHHHHHCCCHHHCCCCEEEEEECCCEEEEEEEEECCCCCC
FDAHTEDVSKVYEKYGFEVKKEDYYKPWAFAKDSELRNLALETYKDLFGKEMKVEVVHAA
CCCCHHHHHHHHHHHCCEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHH
LEPAVFIDTFPDMEMISIGPTMKDVHSPKERLSIESTQRTYEFVKSLLERL
HCCEEEEECCCCCEEEECCCCHHHHCCHHHHHCHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]