Click here to switch to the map view.

The map label for this gene is potE [C]

Identifier: 169823908

GI number: 169823908

Start: 248198

End: 249568

Strand: Direct

Name: potE [C]

Synonym: FMG_0211

Alternate gene names: 169823908

Gene position: 248198-249568 (Clockwise)

Preceding gene: 169823907

Following gene: 169823909

Centisome position: 13.81

GC content: 32.39

Gene sequence:

>1371_bases
ATGAATAATGCAACAAAAAAATTGGGATTTTGGTCAATAGTTCTATTGACTATAAATTCAATAATCGGATCAGGTATATT
TCTATCACCTGGATCTGTAGTTAAAATGTCAGGCAAATATGCACCTTTTATTTATCTAGCAGCAGCAGCTTTTGCAGCGG
TATTGGCAATTACATTTGCTTCTTCTGCAAAATATGTTTCAAAAGGTGGAGCATCATACGCTTATACAAAGGCAGCTTTT
GGAGATAATTGGGGATTGTATATAGGAATTACAAGATTTTTCTCAGCTGCAATAGCCTGGGGAGTAATGGCAACAGGTGT
AGTAAAAACTATGTTAAATATTTTTGGCGCGGATAGCACTAATTTTAACTATATCACTGCTGGATTTATTATTTTGATGA
CAATTTTATTTATAATCAACGTTTGCGGAACAAGGATTTTGGAATTAGTTAGCAATATTTCAACAATAGGTAAGCTCTTG
GCCTTGGTTACTGCGATTGTAGCGGGATTAATATTAGTTATTACTACAGGACAAAACAATTTCTCACAAATAGAAACTGT
TACAGCTGATGTGGCGAATAATATGGATTTAGGAACTATAGTAATGGCAGTGATTGCAGCTTTTTATGCTTTTACTGGAT
TTGAAAGTGTTGCTTCAGGTTCAGAAGATATGGAACAACCAGAAAAAAACTTACCAAAAGCAATTCCACTAGGCATAGTA
ATAATCGCTGTAATATATTTTGGAATCGTACTTGTTTCTATGATGATAGATCCAGTAGCCATGGTAAACACAAAAGAAGT
TGTAGCACTTGTAGCTATATTTAAAAATCATATCGTAAGATCTATAATTCTTTACGGTTCATTAATATCTATGTTTGGAA
TAAACGTAGCTGCATCATTCCATACGCCAAGAATAATAGAATCAATGGCTAATGAAAATCAAGTTCCTAAAATATTTGCA
AAGAGAACAGATAAAGGATTCCCATTGTTCTCAATGGTTATAACTGCTGTTTTGGCAATTATTTTACCTATCGCATTTAA
ATATCACATGGGTTCAATAATGATAATAAGTGCCATCGCAAGATTTGCACAATTCATTGTTGTTCCACTTGCATTGATAT
GGTTTTATTATGGAAAAAACAAGCAAGAAGTTGTAAGCGGAGTAAAGAAAAACTTCTTTACAGATGTTATAATACCAGTT
GTAGCACTTTTACTTACTATAGTATTACTTGCAAAATTTAGTTGGGTAAAACAATTCACTGTTGACAATAATGGTGTATT
AGCTCCAAACTATTTAGCAATAGTATCAATGTTTATTGGATATGTATTAGTACCATTGTTTGTGTATTTCTACAACAATA
AACACAAATAA

Upstream 100 bases:

>100_bases
TAGGTGTTCAATGGCATCCAGAAATGCTTCATTCAACTGAAGAAAAGATGAATCTTTTGTTCAGTGAATTGATAAATAGT
ACTTATTAAAGGAGTAAAAA

Downstream 100 bases:

>100_bases
AATTATAAAGAATATAACATGCCCTCTTAACTATATATAAGTAAGAGGGCATTTCTTTTTCTAACAAATTAGTTGATTAC
AAACTTGGTAGCTGGCGATG

Product: putative amino acid transporter

Products: Proton [Cytoplasm]; putrescine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 456; Mature: 456

Protein sequence:

>456_residues
MNNATKKLGFWSIVLLTINSIIGSGIFLSPGSVVKMSGKYAPFIYLAAAAFAAVLAITFASSAKYVSKGGASYAYTKAAF
GDNWGLYIGITRFFSAAIAWGVMATGVVKTMLNIFGADSTNFNYITAGFIILMTILFIINVCGTRILELVSNISTIGKLL
ALVTAIVAGLILVITTGQNNFSQIETVTADVANNMDLGTIVMAVIAAFYAFTGFESVASGSEDMEQPEKNLPKAIPLGIV
IIAVIYFGIVLVSMMIDPVAMVNTKEVVALVAIFKNHIVRSIILYGSLISMFGINVAASFHTPRIIESMANENQVPKIFA
KRTDKGFPLFSMVITAVLAIILPIAFKYHMGSIMIISAIARFAQFIVVPLALIWFYYGKNKQEVVSGVKKNFFTDVIIPV
VALLLTIVLLAKFSWVKQFTVDNNGVLAPNYLAIVSMFIGYVLVPLFVYFYNNKHK

Sequences:

>Translated_456_residues
MNNATKKLGFWSIVLLTINSIIGSGIFLSPGSVVKMSGKYAPFIYLAAAAFAAVLAITFASSAKYVSKGGASYAYTKAAF
GDNWGLYIGITRFFSAAIAWGVMATGVVKTMLNIFGADSTNFNYITAGFIILMTILFIINVCGTRILELVSNISTIGKLL
ALVTAIVAGLILVITTGQNNFSQIETVTADVANNMDLGTIVMAVIAAFYAFTGFESVASGSEDMEQPEKNLPKAIPLGIV
IIAVIYFGIVLVSMMIDPVAMVNTKEVVALVAIFKNHIVRSIILYGSLISMFGINVAASFHTPRIIESMANENQVPKIFA
KRTDKGFPLFSMVITAVLAIILPIAFKYHMGSIMIISAIARFAQFIVVPLALIWFYYGKNKQEVVSGVKKNFFTDVIIPV
VALLLTIVLLAKFSWVKQFTVDNNGVLAPNYLAIVSMFIGYVLVPLFVYFYNNKHK
>Mature_456_residues
MNNATKKLGFWSIVLLTINSIIGSGIFLSPGSVVKMSGKYAPFIYLAAAAFAAVLAITFASSAKYVSKGGASYAYTKAAF
GDNWGLYIGITRFFSAAIAWGVMATGVVKTMLNIFGADSTNFNYITAGFIILMTILFIINVCGTRILELVSNISTIGKLL
ALVTAIVAGLILVITTGQNNFSQIETVTADVANNMDLGTIVMAVIAAFYAFTGFESVASGSEDMEQPEKNLPKAIPLGIV
IIAVIYFGIVLVSMMIDPVAMVNTKEVVALVAIFKNHIVRSIILYGSLISMFGINVAASFHTPRIIESMANENQVPKIFA
KRTDKGFPLFSMVITAVLAIILPIAFKYHMGSIMIISAIARFAQFIVVPLALIWFYYGKNKQEVVSGVKKNFFTDVIIPV
VALLLTIVLLAKFSWVKQFTVDNNGVLAPNYLAIVSMFIGYVLVPLFVYFYNNKHK

Specific function: Probable amino-acid or metabolite transport protein [H]

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI186910308, Length=252, Percent_Identity=27.7777777777778, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI186910306, Length=252, Percent_Identity=27.7777777777778, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI186910304, Length=252, Percent_Identity=27.7777777777778, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI115648063, Length=253, Percent_Identity=26.4822134387352, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI115648022, Length=253, Percent_Identity=26.4822134387352, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI187423910, Length=253, Percent_Identity=26.4822134387352, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI7657591, Length=253, Percent_Identity=26.4822134387352, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI33286428, Length=347, Percent_Identity=22.7665706051873, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI4507047, Length=416, Percent_Identity=19.9519230769231, Blast_Score=66, Evalue=6e-11,
Organism=Homo sapiens, GI114326544, Length=423, Percent_Identity=19.1489361702128, Blast_Score=66, Evalue=8e-11,
Organism=Homo sapiens, GI114326550, Length=423, Percent_Identity=19.1489361702128, Blast_Score=66, Evalue=8e-11,
Organism=Escherichia coli, GI1786908, Length=333, Percent_Identity=24.6246246246246, Blast_Score=65, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17540018, Length=363, Percent_Identity=26.1707988980716, Blast_Score=82, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI71993915, Length=403, Percent_Identity=23.0769230769231, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI71995382, Length=412, Percent_Identity=22.3300970873786, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71995388, Length=412, Percent_Identity=22.3300970873786, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17531343, Length=362, Percent_Identity=23.4806629834254, Blast_Score=66, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI32566699, Length=309, Percent_Identity=25.5663430420712, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI45550968, Length=357, Percent_Identity=26.6106442577031, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI19921172, Length=357, Percent_Identity=26.6106442577031, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI221512776, Length=362, Percent_Identity=25.1381215469613, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24666159, Length=362, Percent_Identity=25.1381215469613, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24667468, Length=371, Percent_Identity=23.989218328841, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24651635, Length=318, Percent_Identity=24.5283018867925, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24651633, Length=318, Percent_Identity=24.5283018867925, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI221331183, Length=248, Percent_Identity=25, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI17647653, Length=248, Percent_Identity=25, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24664379, Length=248, Percent_Identity=25, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24668806, Length=468, Percent_Identity=21.3675213675214, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21356285, Length=468, Percent_Identity=21.3675213675214, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24668802, Length=468, Percent_Identity=21.3675213675214, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 49445; Mature: 49445

Theoretical pI: Translated: 9.95; Mature: 9.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNATKKLGFWSIVLLTINSIIGSGIFLSPGSVVKMSGKYAPFIYLAAAAFAAVLAITFA
CCCCHHHHHHHHHHHHHHHHHHCCCCEECCCCEEEECCCCCHHHHHHHHHHHHHHHHHHH
SSAKYVSKGGASYAYTKAAFGDNWGLYIGITRFFSAAIAWGVMATGVVKTMLNIFGADST
HHHHHHHCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
NFNYITAGFIILMTILFIINVCGTRILELVSNISTIGKLLALVTAIVAGLILVITTGQNN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCC
FSQIETVTADVANNMDLGTIVMAVIAAFYAFTGFESVASGSEDMEQPEKNLPKAIPLGIV
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCHHHCCCCCCHHHHH
IIAVIYFGIVLVSMMIDPVAMVNTKEVVALVAIFKNHIVRSIILYGSLISMFGINVAASF
HHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
HTPRIIESMANENQVPKIFAKRTDKGFPLFSMVITAVLAIILPIAFKYHMGSIMIISAIA
CCHHHHHHHHCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
RFAQFIVVPLALIWFYYGKNKQEVVSGVKKNFFTDVIIPVVALLLTIVLLAKFSWVKQFT
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
VDNNGVLAPNYLAIVSMFIGYVLVPLFVYFYNNKHK
ECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MNNATKKLGFWSIVLLTINSIIGSGIFLSPGSVVKMSGKYAPFIYLAAAAFAAVLAITFA
CCCCHHHHHHHHHHHHHHHHHHCCCCEECCCCEEEECCCCCHHHHHHHHHHHHHHHHHHH
SSAKYVSKGGASYAYTKAAFGDNWGLYIGITRFFSAAIAWGVMATGVVKTMLNIFGADST
HHHHHHHCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
NFNYITAGFIILMTILFIINVCGTRILELVSNISTIGKLLALVTAIVAGLILVITTGQNN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCC
FSQIETVTADVANNMDLGTIVMAVIAAFYAFTGFESVASGSEDMEQPEKNLPKAIPLGIV
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCHHHCCCCCCHHHHH
IIAVIYFGIVLVSMMIDPVAMVNTKEVVALVAIFKNHIVRSIILYGSLISMFGINVAASF
HHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
HTPRIIESMANENQVPKIFAKRTDKGFPLFSMVITAVLAIILPIAFKYHMGSIMIISAIA
CCHHHHHHHHCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
RFAQFIVVPLALIWFYYGKNKQEVVSGVKKNFFTDVIIPVVALLLTIVLLAKFSWVKQFT
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHE
VDNNGVLAPNYLAIVSMFIGYVLVPLFVYFYNNKHK
ECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; putrescine [Periplasm] [C]

Specific reaction: Proton [Periplasm] + putrescine [Periplasm] = Proton [Cytoplasm] + putrescine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]