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The map label for this gene is dnaC [H]

Identifier: 169823787

GI number: 169823787

Start: 112383

End: 113720

Strand: Direct

Name: dnaC [H]

Synonym: FMG_0090

Alternate gene names: 169823787

Gene position: 112383-113720 (Clockwise)

Preceding gene: 169823786

Following gene: 169823788

Centisome position: 6.25

GC content: 40.36

Gene sequence:

>1338_bases
ATGGAGAATCAACAAAATATTATGCCGTGCGATTTGGAAGCTGAAAGAAGCATAATCGGTGCGATGATAATTGACGAGAG
AGCTGTGGATGATGCGGCGGAAATCGTGGAGCCGGTGGATTTTTATTCTACGAAATACCAAGAAATCTACAAGGCGATTT
TGCAAGTAATTGACGAGAAAAAGCCTGTGGATTACATTACGTTGGAAGACCAATTAAAATCCAATAATATGTACGAAATT
ATCGGTGGAATTGATGAACTTATAAGCATTTCAGAAGCTGTGGGAAGTGCTGTAAATGTAAAATACTACTCAGAAATTGT
CAAAAGCAAGGCGATTATCAGAAATTTGATGCGCGTATCACAAGATGTGATTGATATGTCCATTGCCAACAATTCCGTTG
GAGAGGTTTTGGAATACGCTGAGAGCAATATTTTCAAAATCAGTCAGAACAGAAACCACCAAGATTTGGTTAAAATCCAA
GAAATGTTGGAGCCAACTCTTGCACGAATTGGCGAAATGAGTATGAGCCAAGGACAATTAACTGGTGTTACGACTGGCTT
GATTGATTTGGATAGACAACTTTCGGGGCTACAAAACTCGGATTTGATTTTACTTGCAGCGCGTCCCGCGATGGGAAAAA
CATCACTTGCGCTTAATATTGCATACAAGGCGAGTGTCAAACATCACGTTGCAATTTTTTCTCTTGAAATGAGTAAGATG
CAATTGACTCAAAGATTATTGTCTGCTCTTAGTAACATTAACTTGTCGGAACTTGTGTCTGGTAGAGTTACTGAGTGGAC
AAATTTGGGACAAGCGGCACAGCTATTAGCAGAAAGCAATATGTTTGTCGATGATACTTCGTCGATTTCACTTAACGAGT
TACGTTCCAAATGCAGAAAATTAAAAGCACGTGGCGAATTGGATTTGGTTATTATAGATTATTTGCAACTTATGACGACA
AATTCCAGAAATGAGAACAGACAACAAGAAATCTCCACGATTTCGAGAGGACTCAAAGGCTTGGCGAAAGAATTAAATTG
TCCGATTCTTGCATTGAGCCAATTGTCGCGTGCGCCTGATCAAAGACCGAACCACAGACCAGTCATGAGTGACCTTCGTG
AATCTGGGGCGATCGAACAAGATGCGGATGTTGTGTTGATGTTGTATCGTGATGATTATTACGATCCAGAAACTGACAAG
CCGAATATCGCAGAAATTATCGTCGCAAAACACAGAAACGGTCCAACGGGAACTGTAGATACTTTATTCGACAAGGAACA
CACGAAGTTTATGGATTTGGACAAGCAAATGCCCGATGTAGGAGCGTTTGATAAATGA

Upstream 100 bases:

>100_bases
TAATGTTGTGGTAAAAGTATATCCAGATATTAACGCTAATTTGGAAGTAATTGTAGACAAGGAATAATTTTAAAATACAC
GTAAGAAAGGCGGTGAGGTA

Downstream 100 bases:

>100_bases
TAACTACTGAGAGGTTAACGCTGGAAGGTTTGACATTGAACGATGCATTTGAAATCGAACAATGGGGAAAACACACAGAC
GAACGACTTATCGATTACAA

Product: replicative DNA helicase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 445; Mature: 445

Protein sequence:

>445_residues
MENQQNIMPCDLEAERSIIGAMIIDERAVDDAAEIVEPVDFYSTKYQEIYKAILQVIDEKKPVDYITLEDQLKSNNMYEI
IGGIDELISISEAVGSAVNVKYYSEIVKSKAIIRNLMRVSQDVIDMSIANNSVGEVLEYAESNIFKISQNRNHQDLVKIQ
EMLEPTLARIGEMSMSQGQLTGVTTGLIDLDRQLSGLQNSDLILLAARPAMGKTSLALNIAYKASVKHHVAIFSLEMSKM
QLTQRLLSALSNINLSELVSGRVTEWTNLGQAAQLLAESNMFVDDTSSISLNELRSKCRKLKARGELDLVIIDYLQLMTT
NSRNENRQQEISTISRGLKGLAKELNCPILALSQLSRAPDQRPNHRPVMSDLRESGAIEQDADVVLMLYRDDYYDPETDK
PNIAEIIVAKHRNGPTGTVDTLFDKEHTKFMDLDKQMPDVGAFDK

Sequences:

>Translated_445_residues
MENQQNIMPCDLEAERSIIGAMIIDERAVDDAAEIVEPVDFYSTKYQEIYKAILQVIDEKKPVDYITLEDQLKSNNMYEI
IGGIDELISISEAVGSAVNVKYYSEIVKSKAIIRNLMRVSQDVIDMSIANNSVGEVLEYAESNIFKISQNRNHQDLVKIQ
EMLEPTLARIGEMSMSQGQLTGVTTGLIDLDRQLSGLQNSDLILLAARPAMGKTSLALNIAYKASVKHHVAIFSLEMSKM
QLTQRLLSALSNINLSELVSGRVTEWTNLGQAAQLLAESNMFVDDTSSISLNELRSKCRKLKARGELDLVIIDYLQLMTT
NSRNENRQQEISTISRGLKGLAKELNCPILALSQLSRAPDQRPNHRPVMSDLRESGAIEQDADVVLMLYRDDYYDPETDK
PNIAEIIVAKHRNGPTGTVDTLFDKEHTKFMDLDKQMPDVGAFDK
>Mature_445_residues
MENQQNIMPCDLEAERSIIGAMIIDERAVDDAAEIVEPVDFYSTKYQEIYKAILQVIDEKKPVDYITLEDQLKSNNMYEI
IGGIDELISISEAVGSAVNVKYYSEIVKSKAIIRNLMRVSQDVIDMSIANNSVGEVLEYAESNIFKISQNRNHQDLVKIQ
EMLEPTLARIGEMSMSQGQLTGVTTGLIDLDRQLSGLQNSDLILLAARPAMGKTSLALNIAYKASVKHHVAIFSLEMSKM
QLTQRLLSALSNINLSELVSGRVTEWTNLGQAAQLLAESNMFVDDTSSISLNELRSKCRKLKARGELDLVIIDYLQLMTT
NSRNENRQQEISTISRGLKGLAKELNCPILALSQLSRAPDQRPNHRPVMSDLRESGAIEQDADVVLMLYRDDYYDPETDK
PNIAEIIVAKHRNGPTGTVDTLFDKEHTKFMDLDKQMPDVGAFDK

Specific function: Participates In Initiation And Elongation During Chromosome Replication; It Exhibits DNA-Dependent ATPase Activity And Contains Distinct Active Sites For ATP Binding, DNA Binding, And Interaction With DNAc Protein, Primase, And Other Prepriming Proteins.

COG id: COG0305

COG function: function code L; Replicative DNA helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SF4 helicase domain [H]

Homologues:

Organism=Escherichia coli, GI1790486, Length=435, Percent_Identity=38.8505747126437, Blast_Score=321, Evalue=7e-89,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR007692
- InterPro:   IPR007694
- InterPro:   IPR007693
- InterPro:   IPR016136 [H]

Pfam domain/function: PF00772 DnaB; PF03796 DnaB_C [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 49820; Mature: 49820

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENQQNIMPCDLEAERSIIGAMIIDERAVDDAAEIVEPVDFYSTKYQEIYKAILQVIDEK
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
KPVDYITLEDQLKSNNMYEIIGGIDELISISEAVGSAVNVKYYSEIVKSKAIIRNLMRVS
CCCCEEEEHHHHCCCCHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
QDVIDMSIANNSVGEVLEYAESNIFKISQNRNHQDLVKIQEMLEPTLARIGEMSMSQGQL
HHHHHHHHCCCHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
TGVTTGLIDLDRQLSGLQNSDLILLAARPAMGKTSLALNIAYKASVKHHVAIFSLEMSKM
CCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCEEEEEEEEECCCCCEEEEEEEHHHHH
QLTQRLLSALSNINLSELVSGRVTEWTNLGQAAQLLAESNMFVDDTSSISLNELRSKCRK
HHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHCCCEECCCCCCCHHHHHHHHHH
LKARGELDLVIIDYLQLMTTNSRNENRQQEISTISRGLKGLAKELNCPILALSQLSRAPD
HHHCCCEEEHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCC
QRPNHRPVMSDLRESGAIEQDADVVLMLYRDDYYDPETDKPNIAEIIVAKHRNGPTGTVD
CCCCCCHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHEEEECCCCCCCCHH
TLFDKEHTKFMDLDKQMPDVGAFDK
HHHCCHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MENQQNIMPCDLEAERSIIGAMIIDERAVDDAAEIVEPVDFYSTKYQEIYKAILQVIDEK
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
KPVDYITLEDQLKSNNMYEIIGGIDELISISEAVGSAVNVKYYSEIVKSKAIIRNLMRVS
CCCCEEEEHHHHCCCCHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
QDVIDMSIANNSVGEVLEYAESNIFKISQNRNHQDLVKIQEMLEPTLARIGEMSMSQGQL
HHHHHHHHCCCHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
TGVTTGLIDLDRQLSGLQNSDLILLAARPAMGKTSLALNIAYKASVKHHVAIFSLEMSKM
CCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCEEEEEEEEECCCCCEEEEEEEHHHHH
QLTQRLLSALSNINLSELVSGRVTEWTNLGQAAQLLAESNMFVDDTSSISLNELRSKCRK
HHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHCCCEECCCCCCCHHHHHHHHHH
LKARGELDLVIIDYLQLMTTNSRNENRQQEISTISRGLKGLAKELNCPILALSQLSRAPD
HHHCCCEEEHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCC
QRPNHRPVMSDLRESGAIEQDADVVLMLYRDDYYDPETDKPNIAEIIVAKHRNGPTGTVD
CCCCCCHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHEEEECCCCCCCCHH
TLFDKEHTKFMDLDKQMPDVGAFDK
HHHCCHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 1312531 [H]