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The map label for this gene is ykuC [H]

Identifier: 169823742

GI number: 169823742

Start: 49856

End: 51157

Strand: Direct

Name: ykuC [H]

Synonym: FMG_0045

Alternate gene names: 169823742

Gene position: 49856-51157 (Clockwise)

Preceding gene: 169823741

Following gene: 169823743

Centisome position: 2.77

GC content: 35.25

Gene sequence:

>1302_bases
ATGAACGAAAAATTTAAAAAATTTATGGTGGTATGGTTTGGGCAATTTGTGTCTATGCTTGGGTCGGGAATTTCATCATT
TGGATTATCGTTGTGGATTTTCATGATGACAAAAAGTGCCACGACTTTTGCGATGACGTTTTTAGTACAAATTTTACCGG
GAATTATATTTGCGCCATTTGCAGGATCAATGGCAGACAGAAAACAACGAAAACATATTATAGTGTTAACCGATTCACTT
GATGCTGTACTTAAAGTTATACTTATGATTTTACTTGCGACGGGAAGTATGAAAGTGTGGATGGTGTATCCATTGACATT
TTTGTCGCAAACTTTAGGAACATTTCAAAATCCTGCATTTAATGCGACAATTCCACTTTTGGTTGAAAAGAAGGATATTC
CACGCGCAAATGGTTTTATGCAACTTATCAGAGCAATTCAAAATATGCTTGCGCCGTTGATTGCAGGTGCGTTATTTCCA
TTTATAGGACTTACGGGATTATTTGCGATTGATTTTGTAACTTTCTTCGTCGCTATTTTGACGATTTTACCACAAAAAAT
CGAGCAAGAAATCGAAGAAGTTAAGGAATCTAATTTTACCAAGACAATTGTAAGTGATTTGAAAATAGCTTTTGAAGTGT
TGAAACAAAAGCAAGGATTTATACAAATAATAGTCGTGTTTTCAATATTGAATTTTGTGGCAAATATAGCTATGGTTTTG
GTTGGTCCGTTGGTAATGAGTAATTTCGATACGAAAATATACGGACTTGTAAACTCTGTGTCGGGAATTGCGATGGTGTT
AGGTGGAGTAATTTCGGGAGCAATTCCAAGCGAAAAAAACAAGGTAAGATCGATTTTCCTTAGTTTAATAATTTGCTCAA
TTGGTTTGGTTGTTATGGGAATAAATTACAGTTGGGTTGTGATTGCTGTGGGATTTTTCTTATTTATGATTCCTACTCCT
TATGCGAATGGAACTTTCGGTTCACTGATGCAGTTGAAAATAGAAACTAAAATGCTTGGAAGAGTTGGTTCATTGGTCGA
TTGTCTGATGAAGATTATCACTCCTATAGCGATTATTTTGGCTGGTTTTTTGGCGGATAATGTGTTCAACCCACTCTTGA
TAAAAGGCGGCAAATTATCTGACACTTTCATCGCAAAAATCATTGGAGTGGGAAATGGCAGAGGAATTGGGCTGTTATTT
GTGATTTGTGGAACTATTCTTCTTATCATTTGCGTTATGATGCTTTTGAATAAAAATATTAACCGACTTGAAGAATTAAA
CCCAGATGTAATTAATGATTAG

Upstream 100 bases:

>100_bases
CGGATATGAAGAAAATTGTGTTGAATTTGATACTTTTATATGCAGTGTCTTATCATTTTATGAAAAAAGCAAGGATGAAA
TTACAATATAGGGGATTCTA

Downstream 100 bases:

>100_bases
TTTAGTGTAATTGGGGTATAAATAATCTGTAAGAAATTTTATAGGGGGTAATATAATGGCTAAATTAACAGAAACAGTTC
AATCTGGAGATTGGAAAGCA

Product: macrolide-efflux pump

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 433; Mature: 433

Protein sequence:

>433_residues
MNEKFKKFMVVWFGQFVSMLGSGISSFGLSLWIFMMTKSATTFAMTFLVQILPGIIFAPFAGSMADRKQRKHIIVLTDSL
DAVLKVILMILLATGSMKVWMVYPLTFLSQTLGTFQNPAFNATIPLLVEKKDIPRANGFMQLIRAIQNMLAPLIAGALFP
FIGLTGLFAIDFVTFFVAILTILPQKIEQEIEEVKESNFTKTIVSDLKIAFEVLKQKQGFIQIIVVFSILNFVANIAMVL
VGPLVMSNFDTKIYGLVNSVSGIAMVLGGVISGAIPSEKNKVRSIFLSLIICSIGLVVMGINYSWVVIAVGFFLFMIPTP
YANGTFGSLMQLKIETKMLGRVGSLVDCLMKIITPIAIILAGFLADNVFNPLLIKGGKLSDTFIAKIIGVGNGRGIGLLF
VICGTILLIICVMMLLNKNINRLEELNPDVIND

Sequences:

>Translated_433_residues
MNEKFKKFMVVWFGQFVSMLGSGISSFGLSLWIFMMTKSATTFAMTFLVQILPGIIFAPFAGSMADRKQRKHIIVLTDSL
DAVLKVILMILLATGSMKVWMVYPLTFLSQTLGTFQNPAFNATIPLLVEKKDIPRANGFMQLIRAIQNMLAPLIAGALFP
FIGLTGLFAIDFVTFFVAILTILPQKIEQEIEEVKESNFTKTIVSDLKIAFEVLKQKQGFIQIIVVFSILNFVANIAMVL
VGPLVMSNFDTKIYGLVNSVSGIAMVLGGVISGAIPSEKNKVRSIFLSLIICSIGLVVMGINYSWVVIAVGFFLFMIPTP
YANGTFGSLMQLKIETKMLGRVGSLVDCLMKIITPIAIILAGFLADNVFNPLLIKGGKLSDTFIAKIIGVGNGRGIGLLF
VICGTILLIICVMMLLNKNINRLEELNPDVIND
>Mature_433_residues
MNEKFKKFMVVWFGQFVSMLGSGISSFGLSLWIFMMTKSATTFAMTFLVQILPGIIFAPFAGSMADRKQRKHIIVLTDSL
DAVLKVILMILLATGSMKVWMVYPLTFLSQTLGTFQNPAFNATIPLLVEKKDIPRANGFMQLIRAIQNMLAPLIAGALFP
FIGLTGLFAIDFVTFFVAILTILPQKIEQEIEEVKESNFTKTIVSDLKIAFEVLKQKQGFIQIIVVFSILNFVANIAMVL
VGPLVMSNFDTKIYGLVNSVSGIAMVLGGVISGAIPSEKNKVRSIFLSLIICSIGLVVMGINYSWVVIAVGFFLFMIPTP
YANGTFGSLMQLKIETKMLGRVGSLVDCLMKIITPIAIILAGFLADNVFNPLLIKGGKLSDTFIAKIIGVGNGRGIGLLF
VICGTILLIICVMMLLNKNINRLEELNPDVIND

Specific function: Unknown

COG id: COG0477

COG function: function code GEPR; Permeases of the major facilitator superfamily

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004751
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 47437; Mature: 47437

Theoretical pI: Translated: 9.98; Mature: 9.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEKFKKFMVVWFGQFVSMLGSGISSFGLSLWIFMMTKSATTFAMTFLVQILPGIIFAPF
CCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCC
AGSMADRKQRKHIIVLTDSLDAVLKVILMILLATGSMKVWMVYPLTFLSQTLGTFQNPAF
CCCHHHHHHCCEEEEEECCHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHCCCCC
NATIPLLVEKKDIPRANGFMQLIRAIQNMLAPLIAGALFPFIGLTGLFAIDFVTFFVAIL
CCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TILPQKIEQEIEEVKESNFTKTIVSDLKIAFEVLKQKQGFIQIIVVFSILNFVANIAMVL
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
VGPLVMSNFDTKIYGLVNSVSGIAMVLGGVISGAIPSEKNKVRSIFLSLIICSIGLVVMG
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHC
INYSWVVIAVGFFLFMIPTPYANGTFGSLMQLKIETKMLGRVGSLVDCLMKIITPIAIIL
CCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGFLADNVFNPLLIKGGKLSDTFIAKIIGVGNGRGIGLLFVICGTILLIICVMMLLNKNI
HHHHHHHCCCCCEECCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCH
NRLEELNPDVIND
HHHHHCCCCCCCC
>Mature Secondary Structure
MNEKFKKFMVVWFGQFVSMLGSGISSFGLSLWIFMMTKSATTFAMTFLVQILPGIIFAPF
CCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCC
AGSMADRKQRKHIIVLTDSLDAVLKVILMILLATGSMKVWMVYPLTFLSQTLGTFQNPAF
CCCHHHHHHCCEEEEEECCHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHCCCCC
NATIPLLVEKKDIPRANGFMQLIRAIQNMLAPLIAGALFPFIGLTGLFAIDFVTFFVAIL
CCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TILPQKIEQEIEEVKESNFTKTIVSDLKIAFEVLKQKQGFIQIIVVFSILNFVANIAMVL
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
VGPLVMSNFDTKIYGLVNSVSGIAMVLGGVISGAIPSEKNKVRSIFLSLIICSIGLVVMG
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHC
INYSWVVIAVGFFLFMIPTPYANGTFGSLMQLKIETKMLGRVGSLVDCLMKIITPIAIIL
CCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGFLADNVFNPLLIKGGKLSDTFIAKIIGVGNGRGIGLLFVICGTILLIICVMMLLNKNI
HHHHHHHCCCCCEECCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCH
NRLEELNPDVIND
HHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]