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The map label for this gene is pilQ [H]

Identifier: 167625988

GI number: 167625988

Start: 4968267

End: 4970333

Strand: Reverse

Name: pilQ [H]

Synonym: Shal_4083

Alternate gene names: 167625988

Gene position: 4970333-4968267 (Counterclockwise)

Preceding gene: 167625989

Following gene: 167625987

Centisome position: 95.09

GC content: 41.51

Gene sequence:

>2067_bases
ATGACTGAGGGAACAATGAGATCTTCAACCACGTCAAAAGCCAGTTTTAAGGTGATGCCTTTAGTTAAGGCTATTATTGG
TTTCGTATTAATCGTTGGTATGACTCAGCATTCGTATGCAGCTAACCGACTCATTGATGTGAAATATCACGCCGTTGTTG
ATCACCAACTTGAGTTACAGTTGGTTTTTGAGAATGATATTCAAGAACCTGATATTGATCTAAAGGCCTCGCCAGCGCAG
ATCATTTTGGGATTTGATAACAGTATTTCTGCGCTAGAAAAGCAAACCTTACCGATTAAAACCGTAGGTGTTGAAACGGT
AAGTACTGTACCCAATGGCAATGACTTGCAAGTGTTTATTGGTCTAGACAAGGTAAAGCCGTATCAAGGTAAGGTCGTCG
GTAATACCTATCGTTTAACCATTAACGATGAAGTCGCTAGCGAAGGTGCAAGTAGTGAAAGCCCTTTCGTTAATAACATT
GAAAATATTGATTTTCGTCGCACCGCAGATGGTGGTGGTGAATTATTGGTTAAGCTAAATAATAGCTCTGTGGCTGCTAA
CGTTGAGCAAGTTGGAGCCAAATTAGAGCTTAAACTTTACAATACAGATATTAATCGTGACTTCTTATATGTCATGGATG
TGTATGACTTCGCGACCCCAGTTAAGAGCTTTGAAACTTTTAAAGAAGATCTTACTGCCCGTTTTCTTATCGATATTGAC
GGTGACTATGAATACAACTATCAGCAAGATGGCAGTTTGTTCAAGTTAACGATGAAGAAAAGCGAACGCATGAATATCGT
TAAGGAAGAGAAGAAATATGATGGACGTTCGCTATCGTTAAACTTCCAGAATATTTCGGTTAGAACCGTGCTGCAGATTA
TTGCCGATTACAATAACTTTAACCTAGTGACCAGTGACACGGTTGAAGGCGATATCACCTTAAGGTTGGATGATGTGCCT
TGGGATCAAGCATTAGATCTTATTTTACAAGCTAAAGGTCTAGATAAGCGTATTGAAGGTAATATCTTAATGATTGCGCC
TAGCGAAGAGATCGCTATCCGCGAGAGCCAAGAGTTAAAGAATCGACAGGAAGTGAAGCAGCTTGCACCGCTATATTCTG
AGTATTTACAGATTAATTATGCCAAAGCTAAAGATATTGCGGCACTGTTAAAGGGAGAGGACTCAAGCCTTCTAACTGCT
CGTGGAAGTGTGGCTGTCGATGAACGTACTAACACACTATTGGTTAAAGATACCGAAGAGACGCTTGAAAATGTTCATCG
CTTAATTGAAGTGCTAGATATTCCAATCAAACAGGTATTGATTGAAGCGCGTATGGTGACGGTAAAAGACGATGTTTCAG
AAGATCTTGGTGTACGCTGGGGGGTAACTGACCAGCAAGGAGATAAAGGCACTTCAGGTAGTCTTGAAGGTGCTGGAGAT
ATCGCAAATGGTATCGTTCCAAGCTTAAGCGATCGTTTAAACGTTAATCTTCCCGCAGCTGTAGCTAACCCAACAAGTAT
TGCATTTCATGTGGCAAAGCTTGCCGATGGCACAGTACTCGATCTTGAGTTAAGTGCGCTTGAGCAGGAAAATAAGGGTG
AGATTATTGCTAGCCCGCGTATTACCACCTCTAACCAGAAAGCGGCTTACATCGAGCAAGGTGTAGAGATCCCCTATGTT
GAAGCAAGCTCGAGTGGTGCCACAACGGTAACCTTTAAGAAGGCGGTGTTGTCACTGCGCGTGACGCCACAAATCACACC
TGATAACCGTGTGATTTTAGATCTTGAAATTACTCAAGATTCACAAGGTAAAACCGTAGATACACCGACAGGACAGGCTG
TTTCAATAGATACACAACGTATAGGTACACAAGTGCTGGTGGACCATGGTGAGACGATTGTATTAGGCGGGATCTATCAG
CAACAACTTATTACCAAAGTCAGTAAAGTACCTATATTGGGCGATATCCCATATTTAGGTTTTATGTTCAGAAATAGTTC
TGATAAAAATGAGCGTCAGGAATTGCTAATTTTTGTTACGCCGAAGATAGTCTCAGAAGCGCTATAA

Upstream 100 bases:

>100_bases
AACACCACAAAGTGTCGAAATAATAGAATTAATCCCAGATGGATCTGGCTGCTGGACGGAACGCAACAGTAGTATGGAAT
TGACTGGAGAATAATAAGAG

Downstream 100 bases:

>100_bases
ATTATTTAGCCATACAAAGCCAGTGTAATCCGCTGGCTTTGCCATTTTGGTCGATAGATTTTCGATAGAAATGCATTCCC
CGCTTGCCATAGATGGCACT

Product: type IV pilus secretin PilQ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 688; Mature: 687

Protein sequence:

>688_residues
MTEGTMRSSTTSKASFKVMPLVKAIIGFVLIVGMTQHSYAANRLIDVKYHAVVDHQLELQLVFENDIQEPDIDLKASPAQ
IILGFDNSISALEKQTLPIKTVGVETVSTVPNGNDLQVFIGLDKVKPYQGKVVGNTYRLTINDEVASEGASSESPFVNNI
ENIDFRRTADGGGELLVKLNNSSVAANVEQVGAKLELKLYNTDINRDFLYVMDVYDFATPVKSFETFKEDLTARFLIDID
GDYEYNYQQDGSLFKLTMKKSERMNIVKEEKKYDGRSLSLNFQNISVRTVLQIIADYNNFNLVTSDTVEGDITLRLDDVP
WDQALDLILQAKGLDKRIEGNILMIAPSEEIAIRESQELKNRQEVKQLAPLYSEYLQINYAKAKDIAALLKGEDSSLLTA
RGSVAVDERTNTLLVKDTEETLENVHRLIEVLDIPIKQVLIEARMVTVKDDVSEDLGVRWGVTDQQGDKGTSGSLEGAGD
IANGIVPSLSDRLNVNLPAAVANPTSIAFHVAKLADGTVLDLELSALEQENKGEIIASPRITTSNQKAAYIEQGVEIPYV
EASSSGATTVTFKKAVLSLRVTPQITPDNRVILDLEITQDSQGKTVDTPTGQAVSIDTQRIGTQVLVDHGETIVLGGIYQ
QQLITKVSKVPILGDIPYLGFMFRNSSDKNERQELLIFVTPKIVSEAL

Sequences:

>Translated_688_residues
MTEGTMRSSTTSKASFKVMPLVKAIIGFVLIVGMTQHSYAANRLIDVKYHAVVDHQLELQLVFENDIQEPDIDLKASPAQ
IILGFDNSISALEKQTLPIKTVGVETVSTVPNGNDLQVFIGLDKVKPYQGKVVGNTYRLTINDEVASEGASSESPFVNNI
ENIDFRRTADGGGELLVKLNNSSVAANVEQVGAKLELKLYNTDINRDFLYVMDVYDFATPVKSFETFKEDLTARFLIDID
GDYEYNYQQDGSLFKLTMKKSERMNIVKEEKKYDGRSLSLNFQNISVRTVLQIIADYNNFNLVTSDTVEGDITLRLDDVP
WDQALDLILQAKGLDKRIEGNILMIAPSEEIAIRESQELKNRQEVKQLAPLYSEYLQINYAKAKDIAALLKGEDSSLLTA
RGSVAVDERTNTLLVKDTEETLENVHRLIEVLDIPIKQVLIEARMVTVKDDVSEDLGVRWGVTDQQGDKGTSGSLEGAGD
IANGIVPSLSDRLNVNLPAAVANPTSIAFHVAKLADGTVLDLELSALEQENKGEIIASPRITTSNQKAAYIEQGVEIPYV
EASSSGATTVTFKKAVLSLRVTPQITPDNRVILDLEITQDSQGKTVDTPTGQAVSIDTQRIGTQVLVDHGETIVLGGIYQ
QQLITKVSKVPILGDIPYLGFMFRNSSDKNERQELLIFVTPKIVSEAL
>Mature_687_residues
TEGTMRSSTTSKASFKVMPLVKAIIGFVLIVGMTQHSYAANRLIDVKYHAVVDHQLELQLVFENDIQEPDIDLKASPAQI
ILGFDNSISALEKQTLPIKTVGVETVSTVPNGNDLQVFIGLDKVKPYQGKVVGNTYRLTINDEVASEGASSESPFVNNIE
NIDFRRTADGGGELLVKLNNSSVAANVEQVGAKLELKLYNTDINRDFLYVMDVYDFATPVKSFETFKEDLTARFLIDIDG
DYEYNYQQDGSLFKLTMKKSERMNIVKEEKKYDGRSLSLNFQNISVRTVLQIIADYNNFNLVTSDTVEGDITLRLDDVPW
DQALDLILQAKGLDKRIEGNILMIAPSEEIAIRESQELKNRQEVKQLAPLYSEYLQINYAKAKDIAALLKGEDSSLLTAR
GSVAVDERTNTLLVKDTEETLENVHRLIEVLDIPIKQVLIEARMVTVKDDVSEDLGVRWGVTDQQGDKGTSGSLEGAGDI
ANGIVPSLSDRLNVNLPAAVANPTSIAFHVAKLADGTVLDLELSALEQENKGEIIASPRITTSNQKAAYIEQGVEIPYVE
ASSSGATTVTFKKAVLSLRVTPQITPDNRVILDLEITQDSQGKTVDTPTGQAVSIDTQRIGTQVLVDHGETIVLGGIYQQ
QLITKVSKVPILGDIPYLGFMFRNSSDKNERQELLIFVTPKIVSEAL

Specific function: Essential for the formation of pili. Involved in the biogenesis of type 4 fimbriae probably by serving as a "porthole" allowing passage of the fimbrae through the outer membrane [H]

COG id: COG4796

COG function: function code U; Type II secretory pathway, component HofQ

Gene ontology:

Cell location: Cell outer membrane (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP D family [H]

Homologues:

Organism=Escherichia coli, GI1789793, Length=415, Percent_Identity=38.0722891566265, Blast_Score=267, Evalue=2e-72,
Organism=Escherichia coli, GI87082242, Length=382, Percent_Identity=29.0575916230367, Blast_Score=123, Evalue=5e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001775
- InterPro:   IPR005644
- InterPro:   IPR013355
- InterPro:   IPR011662
- InterPro:   IPR004846
- InterPro:   IPR004845 [H]

Pfam domain/function: PF00263 Secretin; PF03958 Secretin_N; PF07660 STN [H]

EC number: NA

Molecular weight: Translated: 75808; Mature: 75677

Theoretical pI: Translated: 4.48; Mature: 4.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEGTMRSSTTSKASFKVMPLVKAIIGFVLIVGMTQHSYAANRLIDVKYHAVVDHQLELQ
CCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHCCCCCCHHHCEEEEEEEEEEECCEEEEE
LVFENDIQEPDIDLKASPAQIILGFDNSISALEKQTLPIKTVGVETVSTVPNGNDLQVFI
EEEECCCCCCCCCEECCCCEEEEECCCCHHHHHHCCCCEEEECCEEEEECCCCCCEEEEE
GLDKVKPYQGKVVGNTYRLTINDEVASEGASSESPFVNNIENIDFRRTADGGGELLVKLN
EECCCCCCCCEEECCEEEEEECHHHHCCCCCCCCCCCCCCCCCCEEEECCCCCEEEEEEC
NSSVAANVEQVGAKLELKLYNTDINRDFLYVMDVYDFATPVKSFETFKEDLTARFLIDID
CCCEEECHHHCCCEEEEEEEECCCCCCEEEEEEHHHHHHHHHHHHHHHHCCEEEEEEEEC
GDYEYNYQQDGSLFKLTMKKSERMNIVKEEKKYDGRSLSLNFQNISVRTVLQIIADYNNF
CCEEECCCCCCCEEEEEECCCCCCCHHHHHHCCCCCEEEEEECCCHHHHHHHHHHCCCCC
NLVTSDTVEGDITLRLDDVPWDQALDLILQAKGLDKRIEGNILMIAPSEEIAIRESQELK
EEEECCCCCCEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCEEEEECCCCEEECCHHHHH
NRQEVKQLAPLYSEYLQINYAKAKDIAALLKGEDSSLLTARGSVAVDERTNTLLVKDTEE
HHHHHHHHHHHHHHHHEEEEHHHHHHHHHHCCCCCCEEEECCCEEEECCCCEEEEECHHH
TLENVHRLIEVLDIPIKQVLIEARMVTVKDDVSEDLGVRWGVTDQQGDKGTSGSLEGAGD
HHHHHHHHHHHHCCCHHHHHHHHHEEEEECCCCHHCCCEECCCCCCCCCCCCCCCCCCCH
IANGIVPSLSDRLNVNLPAAVANPTSIAFHVAKLADGTVLDLELSALEQENKGEIIASPR
HHCCCCCCCCCCEEECCCEEECCCCHHEEEEEECCCCEEEEEEEHHHCCCCCCCEEECCE
ITTSNQKAAYIEQGVEIPYVEASSSGATTVTFKKAVLSLRVTPQITPDNRVILDLEITQD
EECCCCCHHHHHCCCCCEEEECCCCCCEEEEEEEEEEEEEECCEECCCCEEEEEEEECCC
SQGKTVDTPTGQAVSIDTQRIGTQVLVDHGETIVLGGIYQQQLITKVSKVPILGDIPYLG
CCCCEECCCCCCEEEEEHHHCCCEEEEECCCEEEECCHHHHHHHHHHHCCCEEECCCCEE
FMFRNSSDKNERQELLIFVTPKIVSEAL
EEEECCCCCCCCEEEEEEECHHHHHHCC
>Mature Secondary Structure 
TEGTMRSSTTSKASFKVMPLVKAIIGFVLIVGMTQHSYAANRLIDVKYHAVVDHQLELQ
CCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHCCCCCCHHHCEEEEEEEEEEECCEEEEE
LVFENDIQEPDIDLKASPAQIILGFDNSISALEKQTLPIKTVGVETVSTVPNGNDLQVFI
EEEECCCCCCCCCEECCCCEEEEECCCCHHHHHHCCCCEEEECCEEEEECCCCCCEEEEE
GLDKVKPYQGKVVGNTYRLTINDEVASEGASSESPFVNNIENIDFRRTADGGGELLVKLN
EECCCCCCCCEEECCEEEEEECHHHHCCCCCCCCCCCCCCCCCCEEEECCCCCEEEEEEC
NSSVAANVEQVGAKLELKLYNTDINRDFLYVMDVYDFATPVKSFETFKEDLTARFLIDID
CCCEEECHHHCCCEEEEEEEECCCCCCEEEEEEHHHHHHHHHHHHHHHHCCEEEEEEEEC
GDYEYNYQQDGSLFKLTMKKSERMNIVKEEKKYDGRSLSLNFQNISVRTVLQIIADYNNF
CCEEECCCCCCCEEEEEECCCCCCCHHHHHHCCCCCEEEEEECCCHHHHHHHHHHCCCCC
NLVTSDTVEGDITLRLDDVPWDQALDLILQAKGLDKRIEGNILMIAPSEEIAIRESQELK
EEEECCCCCCEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCEEEEECCCCEEECCHHHHH
NRQEVKQLAPLYSEYLQINYAKAKDIAALLKGEDSSLLTARGSVAVDERTNTLLVKDTEE
HHHHHHHHHHHHHHHHEEEEHHHHHHHHHHCCCCCCEEEECCCEEEECCCCEEEEECHHH
TLENVHRLIEVLDIPIKQVLIEARMVTVKDDVSEDLGVRWGVTDQQGDKGTSGSLEGAGD
HHHHHHHHHHHHCCCHHHHHHHHHEEEEECCCCHHCCCEECCCCCCCCCCCCCCCCCCCH
IANGIVPSLSDRLNVNLPAAVANPTSIAFHVAKLADGTVLDLELSALEQENKGEIIASPR
HHCCCCCCCCCCEEECCCEEECCCCHHEEEEEECCCCEEEEEEEHHHCCCCCCCEEECCE
ITTSNQKAAYIEQGVEIPYVEASSSGATTVTFKKAVLSLRVTPQITPDNRVILDLEITQD
EECCCCCHHHHHCCCCCEEEECCCCCCEEEEEEEEEEEEEECCEECCCCEEEEEEEECCC
SQGKTVDTPTGQAVSIDTQRIGTQVLVDHGETIVLGGIYQQQLITKVSKVPILGDIPYLG
CCCCEECCCCCCEEEEEHHHCCCEEEEECCCEEEECCHHHHHHHHHHHCCCEEECCCCEE
FMFRNSSDKNERQELLIFVTPKIVSEAL
EEEECCCCCCCCEEEEEEECHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7901733; 10984043 [H]