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The map label for this gene is aroB

Identifier: 167625986

GI number: 167625986

Start: 4966454

End: 4967533

Strand: Reverse

Name: aroB

Synonym: Shal_4081

Alternate gene names: 167625986

Gene position: 4967533-4966454 (Counterclockwise)

Preceding gene: 167625987

Following gene: 167625985

Centisome position: 95.04

GC content: 44.91

Gene sequence:

>1080_bases
ATGACTAAACAAGTTCTGGTAGAGCTCGGAGAGCGCAGTTACCCAATTGAAATTGGCCAGAATTTGTTTAGTAATAGCGA
GCCTTTGGCTCGCTATCTTCAACATAAAAATATCCTTATTGTCACTAACGAAACGATAGCGCCTCTCTACCTTCAATCGG
TAGAAGCTATGCTGTCTGATTTCGCGTGCGCCACTCCCGTGATCTTGCCTGATGGCGAGCAATATAAAACCCTTGAACAG
ATGAATGCGATATTCACCTCATTGCTAGAGCAAAATCTAGGTCGAGATACGGTTTTAATTGCATTGGGTGGCGGCGTGAT
TGGCGATATGACCGGTTTTGCTGCAGCTAGCTACCAACGGGGTGTGGATTTCATTCAGATCCCAACAACCTTGTTATCGC
AAGTAGACTCATCTGTTGGTGGTAAAACCGCCGTTAATCACCCGCTAGGTAAAAATATGATAGGAGCCTTCTATCAACCT
AAGTGTGTGTTAATTGACACCAACTGTTTAAGCACTTTACCGAAACGTGAATTTGCAGCTGGCATGGCGGAAGTCATTAA
GTATGGTGTGATTTGGGATGCCGAATTTTTCCAATGGCTTGAAAACAACGTAGAAGCGTTGAAATCATTGGATACACAAG
CGCTTGAATACGCAATTAGTCGTTGCTGCGAAATTAAAGCTGAAGTGGTAGAGAAGGATGAAACCGAACAAGCTGTGCGT
GCACTGCTGAATCTCGGGCATACCTTTGGTCACGCTATTGAAGCTGAAATGGGCTATGGTGTATGGCTGCATGGTGAGGC
TGTTTCAGCTGGCACAGTCCTTGCTGCAATGACCTCAAACAAGCTTGGGTTGGTTGATGAGTCAATTGTTTGTCGTATCA
CAGCGTTATTAGCGGCATTTGATTTACCTATAACCGCACCCGAAACAATGGATTTTGAACAATTCATTAAGCATATGCGC
CGAGACAAGAAGGTGCTCAAAGGTCAATTACGACTCGTTTTACCTGAAGGCATTGGCCAAGCAGGGATCTACAGCGACGT
TACCGATGAGCTACTGGAAGAGGTTATCAACTGCGCATAA

Upstream 100 bases:

>100_bases
TCCTCTTTATGAAGAGATTGCAGACGTCATTGTTAAGACTGACGAGCAAAGTGCCAAAGTTGTTGCAAACCAAATTATTG
AACAGTTAGGTTTTTAATAT

Downstream 100 bases:

>100_bases
ATTATGTTGCAGGTGATAGGTGAACGCTAAACTCAGTATAAAAAAACAAGTCTTAGATTTTTCTTTCCTGGCTATGACCT
TGAGGCATAGTTGTGGATCT

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 359; Mature: 358

Protein sequence:

>359_residues
MTKQVLVELGERSYPIEIGQNLFSNSEPLARYLQHKNILIVTNETIAPLYLQSVEAMLSDFACATPVILPDGEQYKTLEQ
MNAIFTSLLEQNLGRDTVLIALGGGVIGDMTGFAAASYQRGVDFIQIPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQP
KCVLIDTNCLSTLPKREFAAGMAEVIKYGVIWDAEFFQWLENNVEALKSLDTQALEYAISRCCEIKAEVVEKDETEQAVR
ALLNLGHTFGHAIEAEMGYGVWLHGEAVSAGTVLAAMTSNKLGLVDESIVCRITALLAAFDLPITAPETMDFEQFIKHMR
RDKKVLKGQLRLVLPEGIGQAGIYSDVTDELLEEVINCA

Sequences:

>Translated_359_residues
MTKQVLVELGERSYPIEIGQNLFSNSEPLARYLQHKNILIVTNETIAPLYLQSVEAMLSDFACATPVILPDGEQYKTLEQ
MNAIFTSLLEQNLGRDTVLIALGGGVIGDMTGFAAASYQRGVDFIQIPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQP
KCVLIDTNCLSTLPKREFAAGMAEVIKYGVIWDAEFFQWLENNVEALKSLDTQALEYAISRCCEIKAEVVEKDETEQAVR
ALLNLGHTFGHAIEAEMGYGVWLHGEAVSAGTVLAAMTSNKLGLVDESIVCRITALLAAFDLPITAPETMDFEQFIKHMR
RDKKVLKGQLRLVLPEGIGQAGIYSDVTDELLEEVINCA
>Mature_358_residues
TKQVLVELGERSYPIEIGQNLFSNSEPLARYLQHKNILIVTNETIAPLYLQSVEAMLSDFACATPVILPDGEQYKTLEQM
NAIFTSLLEQNLGRDTVLIALGGGVIGDMTGFAAASYQRGVDFIQIPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQPK
CVLIDTNCLSTLPKREFAAGMAEVIKYGVIWDAEFFQWLENNVEALKSLDTQALEYAISRCCEIKAEVVEKDETEQAVRA
LLNLGHTFGHAIEAEMGYGVWLHGEAVSAGTVLAAMTSNKLGLVDESIVCRITALLAAFDLPITAPETMDFEQFIKHMRR
DKKVLKGQLRLVLPEGIGQAGIYSDVTDELLEEVINCA

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family

Homologues:

Organism=Escherichia coli, GI1789791, Length=358, Percent_Identity=58.9385474860335, Blast_Score=421, Evalue=1e-119,
Organism=Saccharomyces cerevisiae, GI6320332, Length=389, Percent_Identity=37.2750642673522, Blast_Score=216, Evalue=4e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROB_SHEHH (B0TL76)

Other databases:

- EMBL:   CP000931
- RefSeq:   YP_001676280.1
- ProteinModelPortal:   B0TL76
- SMR:   B0TL76
- GeneID:   5903084
- GenomeReviews:   CP000931_GR
- KEGG:   shl:Shal_4081
- HOGENOM:   HBG632303
- OMA:   CEIKAEV
- ProtClustDB:   PRK00002
- BioCyc:   SHAL458817:SHAL_4081-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00110
- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037
- PANTHER:   PTHR21090:SF1
- PIRSF:   PIRSF001455
- TIGRFAMs:   TIGR01357

Pfam domain/function: PF01761 DHQ_synthase

EC number: =4.2.3.4

Molecular weight: Translated: 39324; Mature: 39193

Theoretical pI: Translated: 4.44; Mature: 4.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKQVLVELGERSYPIEIGQNLFSNSEPLARYLQHKNILIVTNETIAPLYLQSVEAMLSD
CCHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHH
FACATPVILPDGEQYKTLEQMNAIFTSLLEQNLGRDTVLIALGGGVIGDMTGFAAASYQR
HHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHH
GVDFIQIPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQPKCVLIDTNCLSTLPKREFAA
CCCEEEHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCEEEEEECHHHHHCCHHHHHH
GMAEVIKYGVIWDAEFFQWLENNVEALKSLDTQALEYAISRCCEIKAEVVEKDETEQAVR
HHHHHHHHCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
ALLNLGHTFGHAIEAEMGYGVWLHGEAVSAGTVLAAMTSNKLGLVDESIVCRITALLAAF
HHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHH
DLPITAPETMDFEQFIKHMRRDKKVLKGQLRLVLPEGIGQAGIYSDVTDELLEEVINCA
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TKQVLVELGERSYPIEIGQNLFSNSEPLARYLQHKNILIVTNETIAPLYLQSVEAMLSD
CHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHH
FACATPVILPDGEQYKTLEQMNAIFTSLLEQNLGRDTVLIALGGGVIGDMTGFAAASYQR
HHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHH
GVDFIQIPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQPKCVLIDTNCLSTLPKREFAA
CCCEEEHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCEEEEEECHHHHHCCHHHHHH
GMAEVIKYGVIWDAEFFQWLENNVEALKSLDTQALEYAISRCCEIKAEVVEKDETEQAVR
HHHHHHHHCCEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
ALLNLGHTFGHAIEAEMGYGVWLHGEAVSAGTVLAAMTSNKLGLVDESIVCRITALLAAF
HHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHH
DLPITAPETMDFEQFIKHMRRDKKVLKGQLRLVLPEGIGQAGIYSDVTDELLEEVINCA
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA