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The map label for this gene is gap3 [H]

Identifier: 167625726

GI number: 167625726

Start: 4634411

End: 4635430

Strand: Reverse

Name: gap3 [H]

Synonym: Shal_3821

Alternate gene names: 167625726

Gene position: 4635430-4634411 (Counterclockwise)

Preceding gene: 167625727

Following gene: 167625725

Centisome position: 88.68

GC content: 47.06

Gene sequence:

>1020_bases
ATGACAATCAAAATTGGTATCAATGGCTTCGGTAGAATGGGGCGCCTAGCATTACGCTCGGCTTGGAATAACAGTGAGGT
TGAGTTTGTACAGATCAACGATCCTGCAGGTGATGCACCGACACTAGCCCACTTGCTGACATTTGACTCCATACACGGTC
GTTGGTCTGAAGAAGCAACGGCAGACGGCGATACTATCGTTATTGGAGAAAGCCGCATTGTGACCACTCGTAATAACGCG
ATTGCCGATACCGATTGGTCTGGTTGTGATGTGGTGATTGAAGCGTCTGGTGTGATGAAAACCAAGGCTCTATTGCAAGC
TTACTTAGATCAAGGCGTTAAAAGAGTGGTGGTGACAGCGCCAGTGAAAGAAGAAGGTGTATTGAACGTAGTGATGGGCG
TGAATCATGATCTTTATAATAAAGATATTCACCCCATCGTGACTGCAGCATCGTGTACTACCAACTGCTTAGCGCCAGTG
GTCAAAGTGATCCATGAAAAAATCGGTATCAAGCATGGCTCGATGACCACGATTCATGACATTACCAATACCCAAACGAT
CTTGGATGCCCCCCACAAAGATCTACGTCGCGCCCGTGCTTGTGGTTTAAGCCTTATCCCAACAACCACGGGTAGCGCAA
CGGCAATTACCCATATTTTTCCTGAGCTTAAAGGAAAGCTAAACGGCCATGCAGTGCGTGTGCCATTGGCTAATGCATCC
CTCACAGATTGTGTATTTGAACTAAACCGCGATACCACAGAAGCTGAGGTGAATCAGTTATTACGCGAGGCTGCAGAGGG
AGAGCTTAAAGGTATTCTTGGATACGAAGAACGCCCACTAGTGTCTGTAGATTATAAAACTGACCCTCGCTCAAGCATTA
TTGATGCGCCATCGACCATGGTGGTTAACGGTACCCAAGTTAAACTGTACGTCTGGTATGACAATGAGTGGGGTTATGCT
AACCGTACCGCTGAATTAGCGATTATGGTCGGACGATTGGATCAAGCTGGGAAGTGCTAA

Upstream 100 bases:

>100_bases
TTATAAATAGGTTGAGTTCTGTGCTAGCGCTAAAACGAAAGCAAGAAGCTAGTACAAGAGCTCCAGCTTACAGCATTCAA
TAACAGGTTAAGAGACGATT

Downstream 100 bases:

>100_bases
CAATGGCTCTTTGCTTCTAGGTTCTAGGAAGAGCTGGTTCTAGGTCTTAGGACCTAGGTACTAGGAAAAGCAGGAAAAGC
TAAGACGATGAAAGCTGAGA

Product: glyceraldehyde-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 339; Mature: 338

Protein sequence:

>339_residues
MTIKIGINGFGRMGRLALRSAWNNSEVEFVQINDPAGDAPTLAHLLTFDSIHGRWSEEATADGDTIVIGESRIVTTRNNA
IADTDWSGCDVVIEASGVMKTKALLQAYLDQGVKRVVVTAPVKEEGVLNVVMGVNHDLYNKDIHPIVTAASCTTNCLAPV
VKVIHEKIGIKHGSMTTIHDITNTQTILDAPHKDLRRARACGLSLIPTTTGSATAITHIFPELKGKLNGHAVRVPLANAS
LTDCVFELNRDTTEAEVNQLLREAAEGELKGILGYEERPLVSVDYKTDPRSSIIDAPSTMVVNGTQVKLYVWYDNEWGYA
NRTAELAIMVGRLDQAGKC

Sequences:

>Translated_339_residues
MTIKIGINGFGRMGRLALRSAWNNSEVEFVQINDPAGDAPTLAHLLTFDSIHGRWSEEATADGDTIVIGESRIVTTRNNA
IADTDWSGCDVVIEASGVMKTKALLQAYLDQGVKRVVVTAPVKEEGVLNVVMGVNHDLYNKDIHPIVTAASCTTNCLAPV
VKVIHEKIGIKHGSMTTIHDITNTQTILDAPHKDLRRARACGLSLIPTTTGSATAITHIFPELKGKLNGHAVRVPLANAS
LTDCVFELNRDTTEAEVNQLLREAAEGELKGILGYEERPLVSVDYKTDPRSSIIDAPSTMVVNGTQVKLYVWYDNEWGYA
NRTAELAIMVGRLDQAGKC
>Mature_338_residues
TIKIGINGFGRMGRLALRSAWNNSEVEFVQINDPAGDAPTLAHLLTFDSIHGRWSEEATADGDTIVIGESRIVTTRNNAI
ADTDWSGCDVVIEASGVMKTKALLQAYLDQGVKRVVVTAPVKEEGVLNVVMGVNHDLYNKDIHPIVTAASCTTNCLAPVV
KVIHEKIGIKHGSMTTIHDITNTQTILDAPHKDLRRARACGLSLIPTTTGSATAITHIFPELKGKLNGHAVRVPLANASL
TDCVFELNRDTTEAEVNQLLREAAEGELKGILGYEERPLVSVDYKTDPRSSIIDAPSTMVVNGTQVKLYVWYDNEWGYAN
RTAELAIMVGRLDQAGKC

Specific function: Second phase of glycolysis; first step. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=327, Percent_Identity=41.5902140672783, Blast_Score=267, Evalue=1e-71,
Organism=Homo sapiens, GI7657116, Length=327, Percent_Identity=39.1437308868502, Blast_Score=238, Evalue=7e-63,
Organism=Escherichia coli, GI1788079, Length=329, Percent_Identity=43.4650455927052, Blast_Score=259, Evalue=1e-70,
Organism=Escherichia coli, GI1789295, Length=327, Percent_Identity=39.7553516819572, Blast_Score=247, Evalue=9e-67,
Organism=Caenorhabditis elegans, GI17534677, Length=330, Percent_Identity=40.9090909090909, Blast_Score=258, Evalue=3e-69,
Organism=Caenorhabditis elegans, GI17534679, Length=330, Percent_Identity=40.3030303030303, Blast_Score=256, Evalue=2e-68,
Organism=Caenorhabditis elegans, GI32566163, Length=330, Percent_Identity=40, Blast_Score=254, Evalue=6e-68,
Organism=Caenorhabditis elegans, GI17568413, Length=330, Percent_Identity=40, Blast_Score=254, Evalue=6e-68,
Organism=Saccharomyces cerevisiae, GI6321631, Length=333, Percent_Identity=42.3423423423423, Blast_Score=276, Evalue=5e-75,
Organism=Saccharomyces cerevisiae, GI6322468, Length=333, Percent_Identity=42.042042042042, Blast_Score=274, Evalue=1e-74,
Organism=Saccharomyces cerevisiae, GI6322409, Length=333, Percent_Identity=41.1411411411411, Blast_Score=263, Evalue=4e-71,
Organism=Drosophila melanogaster, GI19922412, Length=335, Percent_Identity=39.1044776119403, Blast_Score=251, Evalue=7e-67,
Organism=Drosophila melanogaster, GI85725000, Length=326, Percent_Identity=41.1042944785276, Blast_Score=250, Evalue=1e-66,
Organism=Drosophila melanogaster, GI22023983, Length=326, Percent_Identity=41.1042944785276, Blast_Score=250, Evalue=1e-66,
Organism=Drosophila melanogaster, GI17933600, Length=326, Percent_Identity=40.7975460122699, Blast_Score=249, Evalue=2e-66,
Organism=Drosophila melanogaster, GI18110149, Length=326, Percent_Identity=40.7975460122699, Blast_Score=249, Evalue=2e-66,

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 740 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1660 Molecules/Cell In: Growth Phase, Min

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 36812; Mature: 36681

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIKIGINGFGRMGRLALRSAWNNSEVEFVQINDPAGDAPTLAHLLTFDSIHGRWSEEAT
CEEEEECCCCCHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCC
ADGDTIVIGESRIVTTRNNAIADTDWSGCDVVIEASGVMKTKALLQAYLDQGVKRVVVTA
CCCCEEEEECCEEEEECCCEECCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCEEEEEEC
PVKEEGVLNVVMGVNHDLYNKDIHPIVTAASCTTNCLAPVVKVIHEKIGIKHGSMTTIHD
CCCCCCCEEEEEECCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEE
ITNTQTILDAPHKDLRRARACGLSLIPTTTGSATAITHIFPELKGKLNGHAVRVPLANAS
CCCCCHHHCCCHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHCCCCCCEEEEEEECCCC
LTDCVFELNRDTTEAEVNQLLREAAEGELKGILGYEERPLVSVDYKTDPRSSIIDAPSTM
HHHHHHCCCCCCCHHHHHHHHHHHHCCCEEEECCCCCCCEEEEECCCCCCHHHCCCCCEE
VVNGTQVKLYVWYDNEWGYANRTAELAIMVGRLDQAGKC
EEECCEEEEEEEECCCCCCCCCCEEEEEEEECCCCCCCC
>Mature Secondary Structure 
TIKIGINGFGRMGRLALRSAWNNSEVEFVQINDPAGDAPTLAHLLTFDSIHGRWSEEAT
EEEEECCCCCHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCC
ADGDTIVIGESRIVTTRNNAIADTDWSGCDVVIEASGVMKTKALLQAYLDQGVKRVVVTA
CCCCEEEEECCEEEEECCCEECCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCEEEEEEC
PVKEEGVLNVVMGVNHDLYNKDIHPIVTAASCTTNCLAPVVKVIHEKIGIKHGSMTTIHD
CCCCCCCEEEEEECCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEE
ITNTQTILDAPHKDLRRARACGLSLIPTTTGSATAITHIFPELKGKLNGHAVRVPLANAS
CCCCCHHHCCCHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHCCCCCCEEEEEEECCCC
LTDCVFELNRDTTEAEVNQLLREAAEGELKGILGYEERPLVSVDYKTDPRSSIIDAPSTM
HHHHHHCCCCCCCHHHHHHHHHHHHCCCEEEECCCCCCCEEEEECCCCCCHHHCCCCCEE
VVNGTQVKLYVWYDNEWGYANRTAELAIMVGRLDQAGKC
EEECCEEEEEEEECCCCCCCCCCEEEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8378350 [H]