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The map label for this gene is caiD [C]

Identifier: 167625699

GI number: 167625699

Start: 4610725

End: 4611531

Strand: Reverse

Name: caiD [C]

Synonym: Shal_3794

Alternate gene names: 167625699

Gene position: 4611531-4610725 (Counterclockwise)

Preceding gene: 167625702

Following gene: 167625698

Centisome position: 88.23

GC content: 45.35

Gene sequence:

>807_bases
ATGACTTATGATTTAGTACGCGTCGTCAAAAAAAATGGCATTGCTTACGTGAGTCTTAATCGACCTGAAAAGTATAATGC
ACTGAATTGTAGACTTTTTTGTGAGATTGAACACTGTATAAAAACATTGTCGAAAGACCGAACGCTTACTGCGGTGGTTC
TTTTCGGTGAAGGGGGCAATTTTAGCTCAGGTTTAGATGTAAAAAGTGTGATGAGCTCGCCTTTAGATGCAGTTAAACTA
TTATTTAAGTTTCTACCGGGGAATGCCAATTTGGCGCAGAGGGTCTCCATTGGTTGGCGTCGATTACCTGTACCTGTCAT
CGCGGTACTCGAGGGGGTGTGTTATGGCGGTGGTATGCAGATCGTTCTTGGAGCCGATTTTAGAATAGCGGATCCCGATT
GTAAAATGTCGATAATGGAAGCGAAATGGGGCTTGGTTCCTGATATGGCTGGTTTGGTTGGTTTACGAGAGTTAATGCCA
AAAGATCAGGCGCTTATGTTAACGATGTCGGCGGATGTATTGACTGCAGAGCAGGCGCTTGCCGCTAACCTTGTGACCTC
GGTAGAAGCTGAGCCATTAGCCGCAGCTACGGCTCTAGCGACCAAATTGTCGCAAACGTCCCCTGATGCCAATGCGGCTA
TCAAGCGCAGTATTAATAACAATTGGTCGGCCTCTATTCGGCAATTACTCAGGCGCGAGTCCTGGTATCAAATACGATTA
TTACTGGGAAAAAATCGAATGATTGCAGCGTTAAGACAAGGTAAGGATCCAGATAAGAGATATCGAAATCGGCAGTCAGG
TTGGTAG

Upstream 100 bases:

>100_bases
AGTGTCATAATTTCACCGCATGTTATATCTATTAACCTAATATGCCAAATGTGTTAACTTGTTCAGTCTGGACAGACCAC
TTGCCAAGAAAGGCCTTAAT

Downstream 100 bases:

>100_bases
TTTTTAGTAAAAAGCATTAAGCGTGATCTGGTTCACGAATTGCTGTGATTTTTATGTCGTAGGCAGGCGCTTCTTTTACA
CTTCCCGCCTATTTATTGTT

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: 3-hydroxypropionyl-CoA dehydratase [H]

Number of amino acids: Translated: 268; Mature: 267

Protein sequence:

>268_residues
MTYDLVRVVKKNGIAYVSLNRPEKYNALNCRLFCEIEHCIKTLSKDRTLTAVVLFGEGGNFSSGLDVKSVMSSPLDAVKL
LFKFLPGNANLAQRVSIGWRRLPVPVIAVLEGVCYGGGMQIVLGADFRIADPDCKMSIMEAKWGLVPDMAGLVGLRELMP
KDQALMLTMSADVLTAEQALAANLVTSVEAEPLAAATALATKLSQTSPDANAAIKRSINNNWSASIRQLLRRESWYQIRL
LLGKNRMIAALRQGKDPDKRYRNRQSGW

Sequences:

>Translated_268_residues
MTYDLVRVVKKNGIAYVSLNRPEKYNALNCRLFCEIEHCIKTLSKDRTLTAVVLFGEGGNFSSGLDVKSVMSSPLDAVKL
LFKFLPGNANLAQRVSIGWRRLPVPVIAVLEGVCYGGGMQIVLGADFRIADPDCKMSIMEAKWGLVPDMAGLVGLRELMP
KDQALMLTMSADVLTAEQALAANLVTSVEAEPLAAATALATKLSQTSPDANAAIKRSINNNWSASIRQLLRRESWYQIRL
LLGKNRMIAALRQGKDPDKRYRNRQSGW
>Mature_267_residues
TYDLVRVVKKNGIAYVSLNRPEKYNALNCRLFCEIEHCIKTLSKDRTLTAVVLFGEGGNFSSGLDVKSVMSSPLDAVKLL
FKFLPGNANLAQRVSIGWRRLPVPVIAVLEGVCYGGGMQIVLGADFRIADPDCKMSIMEAKWGLVPDMAGLVGLRELMPK
DQALMLTMSADVLTAEQALAANLVTSVEAEPLAAATALATKLSQTSPDANAAIKRSINNNWSASIRQLLRRESWYQIRLL
LGKNRMIAALRQGKDPDKRYRNRQSGW

Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the reversible dehydration of 3-hydroxypropionyl-CoA to form acryloyl- CoA, and the reversible dehydration of (S)-3-hydroxybutyryl-CoA to form crot

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI70995211, Length=197, Percent_Identity=31.9796954314721, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI213417737, Length=239, Percent_Identity=26.3598326359833, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI157694516, Length=239, Percent_Identity=26.3598326359833, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI194097323, Length=221, Percent_Identity=27.1493212669683, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI68989263, Length=195, Percent_Identity=28.2051282051282, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI157694520, Length=200, Percent_Identity=27, Blast_Score=66, Evalue=4e-11,
Organism=Escherichia coli, GI221142681, Length=231, Percent_Identity=28.5714285714286, Blast_Score=81, Evalue=9e-17,
Organism=Escherichia coli, GI1790281, Length=216, Percent_Identity=27.3148148148148, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1787659, Length=262, Percent_Identity=25.9541984732824, Blast_Score=74, Evalue=7e-15,
Organism=Escherichia coli, GI1787660, Length=240, Percent_Identity=30, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1788682, Length=223, Percent_Identity=28.2511210762332, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI87082183, Length=222, Percent_Identity=24.3243243243243, Blast_Score=66, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17540714, Length=237, Percent_Identity=29.535864978903, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI25145438, Length=231, Percent_Identity=27.2727272727273, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17534483, Length=255, Percent_Identity=25.8823529411765, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17536985, Length=218, Percent_Identity=25.2293577981651, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17560910, Length=209, Percent_Identity=24.8803827751196, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17554946, Length=229, Percent_Identity=23.1441048034935, Blast_Score=70, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17558304, Length=209, Percent_Identity=25.8373205741627, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI20129971, Length=222, Percent_Identity=24.7747747747748, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24653477, Length=222, Percent_Identity=24.7747747747748, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24653139, Length=199, Percent_Identity=29.1457286432161, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI19922422, Length=191, Percent_Identity=27.7486910994764, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI19920382, Length=221, Percent_Identity=24.8868778280543, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI21357171, Length=200, Percent_Identity=23, Blast_Score=64, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.116 [H]

Molecular weight: Translated: 29498; Mature: 29367

Theoretical pI: Translated: 10.03; Mature: 10.03

Prosite motif: PS00166 ENOYL_COA_HYDRATASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYDLVRVVKKNGIAYVSLNRPEKYNALNCRLFCEIEHCIKTLSKDRTLTAVVLFGEGGN
CCHHHHHHHHHCCEEEEECCCCCCCCCEEEEEEEEHHHHHHHHCCCCEEEEEEEEECCCC
FSSGLDVKSVMSSPLDAVKLLFKFLPGNANLAQRVSIGWRRLPVPVIAVLEGVCYGGGMQ
CCCCCCHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHCCCCEE
IVLGADFRIADPDCKMSIMEAKWGLVPDMAGLVGLRELMPKDQALMLTMSADVLTAEQAL
EEEECCEEEECCCCCEEHHHHHCCCCCHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHH
AANLVTSVEAEPLAAATALATKLSQTSPDANAAIKRSINNNWSASIRQLLRRESWYQIRL
HHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCEEEEE
LLGKNRMIAALRQGKDPDKRYRNRQSGW
EECCCHHHHHHHCCCCHHHHHHCCCCCC
>Mature Secondary Structure 
TYDLVRVVKKNGIAYVSLNRPEKYNALNCRLFCEIEHCIKTLSKDRTLTAVVLFGEGGN
CHHHHHHHHHCCEEEEECCCCCCCCCEEEEEEEEHHHHHHHHCCCCEEEEEEEEECCCC
FSSGLDVKSVMSSPLDAVKLLFKFLPGNANLAQRVSIGWRRLPVPVIAVLEGVCYGGGMQ
CCCCCCHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHCCCCEE
IVLGADFRIADPDCKMSIMEAKWGLVPDMAGLVGLRELMPKDQALMLTMSADVLTAEQAL
EEEECCEEEECCCCCEEHHHHHCCCCCHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHH
AANLVTSVEAEPLAAATALATKLSQTSPDANAAIKRSINNNWSASIRQLLRRESWYQIRL
HHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCEEEEE
LLGKNRMIAALRQGKDPDKRYRNRQSGW
EECCCHHHHHHHCCCCHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA