Click here to switch to the map view.

The map label for this gene is murA

Identifier: 167625597

GI number: 167625597

Start: 4494527

End: 4495789

Strand: Reverse

Name: murA

Synonym: Shal_3692

Alternate gene names: 167625597

Gene position: 4495789-4494527 (Counterclockwise)

Preceding gene: 167625598

Following gene: 167625596

Centisome position: 86.01

GC content: 49.88

Gene sequence:

>1263_bases
GTGGATAAATTAAAAATTGAAGCAAGTGGTGCACTTGCTGGAAACGTGGTTATCTCTGGCGCTAAAAATGCTGCCTTGCC
AATTTTAATGGCGGGCGTGCTGGCCGAGACTGACTTCAATGTTTCTAACGTACCAAACCTAAGAGATGTGAACACCAGCT
GTGAGCTACTGCGCTGCTTGGGTGCTGAAGTAACCCGTTCTGGCACTGATAAAGTGTGTATCTCTACCACCAATCTAAAT
GAATTTTGTGCGCCGTATGAGTTGGTAAAAACCATGCGCGCATCGATTCTTATTCTAGGCCCTCTACTTGCACGCTACGG
TACTGCCGATGTGTCTCTGCCGGGTGGCTGCGCCATTGGTGCACGTCCTGTTAACTTGCACTTGCAAGGTCTTGAGCAGA
TGGGCGCCAAGATTGAGGTTAAAGAAGGCTATATCAAAGCACGTGTTGACGGTCGTTTGAAAGGCGCGCATATCTTTATG
GATATGATCAGCGTTGGCGCGACGGAGAACTTGCTAATGGCTGCAGCACTGGCCGATGGTGAAACCATTATCGAAAATGC
TGCCCGTGAGCCTGAGGTCGTAGATTTGGCTAACTGCCTAATCGCAATGGGTGCCAAGATTGAAGGTGCGGGTACCGATA
CCGTGCGTATTCAGGGCGTGGAGTCACTGCAAGGCTGTGACTACCAAGTGATGCCTGACCGCATCGAAACCGGAAGTTTC
TTGGTCGCTGCGGCTGTGACGCGCGGTAAAATCCGTTGCACTAAGGCTGATCCTAAAACCCTTGAGTCTGTGCTGGCTAA
GCTTGAAGACGCTGGCGCATCGATCACAACGGGTGATGATTGGATTGAGCTTGATATGCAGGGTAAACGTCCTAAAGCGG
TAAACATCAAGACTGTAGCTTACCCAGGTTTCCCAACCGATATGCAGGCGCAATTCTGTGTGCTTAACGCACTCGCCGAA
GGCACCGCAACCATTACCGAAACCATTTTCGAAAACCGCTTTATGCATGTTCCTGAGCTTAGCCGCATGGGCGCAACCAT
GGAGCTTGAAGGTAATACCTGTATCATCCATGGCATCGAGAAGCTTAACGGTGCGCAGGTGATGGCAACGGATCTACGTG
CGTCAGCAAGCCTTGTGATTGCAGGTCTTGTGGCTGAAGGAACGACGATTGTTGATCGTATCTATCACTTAGACCGTGGT
TATGAGCATATTGAAGATAAGTTTAAAGGCTTAGGCGGACACGTCGAGCGTGTTAAGTCGTAA

Upstream 100 bases:

>100_bases
TAGCGGTGAGTTACACGCTATTACGATTAACGCATTCACGCCAACACAATGGAAGCGTGAAAAAGTCTTTAATATGTAAT
CGCGGATTTAGAGAGTTAAA

Downstream 100 bases:

>100_bases
CGTTTAAGCTGTTTTAATGAAGAGCCATTTGAGTTTTAAACTTAAATGGCTTTTTTGTTTTATGAGCTAGCGCAAGTTAC
AGCCTAACAAAATAGGAAGC

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT

Number of amino acids: Translated: 420; Mature: 420

Protein sequence:

>420_residues
MDKLKIEASGALAGNVVISGAKNAALPILMAGVLAETDFNVSNVPNLRDVNTSCELLRCLGAEVTRSGTDKVCISTTNLN
EFCAPYELVKTMRASILILGPLLARYGTADVSLPGGCAIGARPVNLHLQGLEQMGAKIEVKEGYIKARVDGRLKGAHIFM
DMISVGATENLLMAAALADGETIIENAAREPEVVDLANCLIAMGAKIEGAGTDTVRIQGVESLQGCDYQVMPDRIETGSF
LVAAAVTRGKIRCTKADPKTLESVLAKLEDAGASITTGDDWIELDMQGKRPKAVNIKTVAYPGFPTDMQAQFCVLNALAE
GTATITETIFENRFMHVPELSRMGATMELEGNTCIIHGIEKLNGAQVMATDLRASASLVIAGLVAEGTTIVDRIYHLDRG
YEHIEDKFKGLGGHVERVKS

Sequences:

>Translated_420_residues
MDKLKIEASGALAGNVVISGAKNAALPILMAGVLAETDFNVSNVPNLRDVNTSCELLRCLGAEVTRSGTDKVCISTTNLN
EFCAPYELVKTMRASILILGPLLARYGTADVSLPGGCAIGARPVNLHLQGLEQMGAKIEVKEGYIKARVDGRLKGAHIFM
DMISVGATENLLMAAALADGETIIENAAREPEVVDLANCLIAMGAKIEGAGTDTVRIQGVESLQGCDYQVMPDRIETGSF
LVAAAVTRGKIRCTKADPKTLESVLAKLEDAGASITTGDDWIELDMQGKRPKAVNIKTVAYPGFPTDMQAQFCVLNALAE
GTATITETIFENRFMHVPELSRMGATMELEGNTCIIHGIEKLNGAQVMATDLRASASLVIAGLVAEGTTIVDRIYHLDRG
YEHIEDKFKGLGGHVERVKS
>Mature_420_residues
MDKLKIEASGALAGNVVISGAKNAALPILMAGVLAETDFNVSNVPNLRDVNTSCELLRCLGAEVTRSGTDKVCISTTNLN
EFCAPYELVKTMRASILILGPLLARYGTADVSLPGGCAIGARPVNLHLQGLEQMGAKIEVKEGYIKARVDGRLKGAHIFM
DMISVGATENLLMAAALADGETIIENAAREPEVVDLANCLIAMGAKIEGAGTDTVRIQGVESLQGCDYQVMPDRIETGSF
LVAAAVTRGKIRCTKADPKTLESVLAKLEDAGASITTGDDWIELDMQGKRPKAVNIKTVAYPGFPTDMQAQFCVLNALAE
GTATITETIFENRFMHVPELSRMGATMELEGNTCIIHGIEKLNGAQVMATDLRASASLVIAGLVAEGTTIVDRIYHLDRG
YEHIEDKFKGLGGHVERVKS

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily

Homologues:

Organism=Escherichia coli, GI1789580, Length=419, Percent_Identity=67.3031026252983, Blast_Score=583, Evalue=1e-168,
Organism=Escherichia coli, GI1787137, Length=423, Percent_Identity=25.7683215130024, Blast_Score=68, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURA_SHEHH (B0TUW5)

Other databases:

- EMBL:   CP000931
- RefSeq:   YP_001675891.1
- ProteinModelPortal:   B0TUW5
- SMR:   B0TUW5
- GeneID:   5905905
- GenomeReviews:   CP000931_GR
- KEGG:   shl:Shal_3692
- HOGENOM:   HBG482701
- OMA:   MVKTMRA
- ProtClustDB:   PRK09369
- BioCyc:   SHAL458817:SHAL_3692-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00111
- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750
- Gene3D:   G3DSA:3.65.10.10
- PANTHER:   PTHR21090:SF4
- TIGRFAMs:   TIGR01072

Pfam domain/function: PF00275 EPSP_synthase; SSF55205 RNA3'_cycl/enolpyr_transf_A/B

EC number: =2.5.1.7

Molecular weight: Translated: 44720; Mature: 44720

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: NA

Important sites: ACT_SITE 117-117

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKLKIEASGALAGNVVISGAKNAALPILMAGVLAETDFNVSNVPNLRDVNTSCELLRCL
CCCEEEEECCCEECCEEEECCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHH
GAEVTRSGTDKVCISTTNLNEFCAPYELVKTMRASILILGPLLARYGTADVSLPGGCAIG
CCHHHCCCCCEEEEEECCCHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEC
ARPVNLHLQGLEQMGAKIEVKEGYIKARVDGRLKGAHIFMDMISVGATENLLMAAALADG
CEEEEEEEEEHHHCCCEEEEECCEEEEEECCCCCHHHHHHHHHHCCCCCHHEEEEECCCC
ETIIENAAREPEVVDLANCLIAMGAKIEGAGTDTVRIQGVESLQGCDYQVMPDRIETGSF
HHHHHHCCCCCCHHHHHHHHHHHCCEEECCCCCEEEEEECHHHCCCCEEECCCCCCCCCE
LVAAAVTRGKIRCTKADPKTLESVLAKLEDAGASITTGDDWIELDMQGKRPKAVNIKTVA
EEEEEECCCEEEEECCCHHHHHHHHHHHHHCCCEEECCCCEEEEECCCCCCCEEEEEEEE
YPGFPTDMQAQFCVLNALAEGTATITETIFENRFMHVPELSRMGATMELEGNTCIIHGIE
ECCCCCCCCHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCHHHCCCEEEECCCEEEEEEHH
KLNGAQVMATDLRASASLVIAGLVAEGTTIVDRIYHLDRGYEHIEDKFKGLGGHVERVKS
HCCCCEEEEEHHHCCCEEEEEEHHHCCHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHCC
>Mature Secondary Structure
MDKLKIEASGALAGNVVISGAKNAALPILMAGVLAETDFNVSNVPNLRDVNTSCELLRCL
CCCEEEEECCCEECCEEEECCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHH
GAEVTRSGTDKVCISTTNLNEFCAPYELVKTMRASILILGPLLARYGTADVSLPGGCAIG
CCHHHCCCCCEEEEEECCCHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEC
ARPVNLHLQGLEQMGAKIEVKEGYIKARVDGRLKGAHIFMDMISVGATENLLMAAALADG
CEEEEEEEEEHHHCCCEEEEECCEEEEEECCCCCHHHHHHHHHHCCCCCHHEEEEECCCC
ETIIENAAREPEVVDLANCLIAMGAKIEGAGTDTVRIQGVESLQGCDYQVMPDRIETGSF
HHHHHHCCCCCCHHHHHHHHHHHCCEEECCCCCEEEEEECHHHCCCCEEECCCCCCCCCE
LVAAAVTRGKIRCTKADPKTLESVLAKLEDAGASITTGDDWIELDMQGKRPKAVNIKTVA
EEEEEECCCEEEEECCCHHHHHHHHHHHHHCCCEEECCCCEEEEECCCCCCCEEEEEEEE
YPGFPTDMQAQFCVLNALAEGTATITETIFENRFMHVPELSRMGATMELEGNTCIIHGIE
ECCCCCCCCHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCHHHCCCEEEECCCEEEEEEHH
KLNGAQVMATDLRASASLVIAGLVAEGTTIVDRIYHLDRGYEHIEDKFKGLGGHVERVKS
HCCCCEEEEEHHHCCCEEEEEEHHHCCHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA