Click here to switch to the map view.

The map label for this gene is algB [H]

Identifier: 167625595

GI number: 167625595

Start: 4492353

End: 4492991

Strand: Reverse

Name: algB [H]

Synonym: Shal_3690

Alternate gene names: 167625595

Gene position: 4492991-4492353 (Counterclockwise)

Preceding gene: 167625596

Following gene: 167625594

Centisome position: 85.96

GC content: 43.97

Gene sequence:

>639_bases
ATGATCACTATTCTATTGGCGGAAGACGACGTTGAACTTAGGCTAAATATGGTTGAGATTCTAGAGCTTGAGGGTTTTAG
TGTCACCGCTGTTGAAAGCGCGGAAGCCGCAATAAGGGTGAGTGAGAAGCAGCATTTTGATATAGCACTGATGGATCTAC
TGATGGCGGGCATGACAGGGGTTGAAGCTATCTCGAACCTGAGGCAAAACCAGCCGTTAATCGCCGTTATAATTATTACC
GCCTATGCCACCGTCGATACTGCTGTCGATGCGATGAAAAAAGGCGCAGATAGCGTGATGACTAAGCCCTTTAAAAGTAA
CGAGCTCATCGTCACCATAAGGCGTAGCCTCGCGGAAAAACAGCTGTTCAAGAGTCGCGTCGATCTCGACCCCGATTTAG
TCTACAGCGCACTGGCTAACCCTTATCGACGTAAATCCCTTAAAGTTTTGGCAACGCATAAGGCTGTTAAGTTTATGGAC
TTATGTCGTTTAGTTGAAATTGAGGATCATACAAAGTTTAATTTTCATCTGCGGCAGTTAAAAAAGGCAGGCCTTGTTAT
GCAAAATGAGAACAAGCTCTACATTTTGACAAATACAGGCCAACATGTGTTAACAAATCATAACATTTCTCAAGACTGA

Upstream 100 bases:

>100_bases
GTGAACAGATAGTCACACTACATAATGGCAAGATGCATATTACGAGTAGTAAAGAGAAGGGCACTCGTGTGGAACTCACT
TTTTATCGGGAGCAGCATTG

Downstream 100 bases:

>100_bases
ATATTCTATTTAAACAGTGCGTTAGCTCATGGTTGATAACTATAGTTCACAACTTTCCGGTAGCCGTGAATTCTAGTTAT
CTATCTCTTTAGTGGTAACT

Product: response regulator receiver protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 212; Mature: 212

Protein sequence:

>212_residues
MITILLAEDDVELRLNMVEILELEGFSVTAVESAEAAIRVSEKQHFDIALMDLLMAGMTGVEAISNLRQNQPLIAVIIIT
AYATVDTAVDAMKKGADSVMTKPFKSNELIVTIRRSLAEKQLFKSRVDLDPDLVYSALANPYRRKSLKVLATHKAVKFMD
LCRLVEIEDHTKFNFHLRQLKKAGLVMQNENKLYILTNTGQHVLTNHNISQD

Sequences:

>Translated_212_residues
MITILLAEDDVELRLNMVEILELEGFSVTAVESAEAAIRVSEKQHFDIALMDLLMAGMTGVEAISNLRQNQPLIAVIIIT
AYATVDTAVDAMKKGADSVMTKPFKSNELIVTIRRSLAEKQLFKSRVDLDPDLVYSALANPYRRKSLKVLATHKAVKFMD
LCRLVEIEDHTKFNFHLRQLKKAGLVMQNENKLYILTNTGQHVLTNHNISQD
>Mature_212_residues
MITILLAEDDVELRLNMVEILELEGFSVTAVESAEAAIRVSEKQHFDIALMDLLMAGMTGVEAISNLRQNQPLIAVIIIT
AYATVDTAVDAMKKGADSVMTKPFKSNELIVTIRRSLAEKQLFKSRVDLDPDLVYSALANPYRRKSLKVLATHKAVKFMD
LCRLVEIEDHTKFNFHLRQLKKAGLVMQNENKLYILTNTGQHVLTNHNISQD

Specific function: Member of the two-component regulatory system AlgB/KinB involved in regulation of alginate biosynthesis genes. Positive regulator of the alginate biosynthetic gene AlgD [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=160, Percent_Identity=29.375, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI1790437, Length=117, Percent_Identity=34.1880341880342, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1790299, Length=118, Percent_Identity=27.9661016949153, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1788905, Length=116, Percent_Identity=32.7586206896552, Blast_Score=64, Evalue=7e-12,
Organism=Escherichia coli, GI1789809, Length=111, Percent_Identity=30.6306306306306, Blast_Score=62, Evalue=2e-11,
Organism=Escherichia coli, GI1786599, Length=113, Percent_Identity=29.2035398230088, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 23838; Mature: 23838

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITILLAEDDVELRLNMVEILELEGFSVTAVESAEAAIRVSEKQHFDIALMDLLMAGMTG
CEEEEEECCCCEEEEEHHHEEEECCCEEEEECCCCCEEEECCCCCCHHHHHHHHHHCCHH
VEAISNLRQNQPLIAVIIITAYATVDTAVDAMKKGADSVMTKPFKSNELIVTIRRSLAEK
HHHHHHHHCCCCEEEEEEEEHHHHHHHHHHHHHCCHHHHHCCCCCCCCEEEEEHHHHHHH
QLFKSRVDLDPDLVYSALANPYRRKSLKVLATHKAVKFMDLCRLVEIEDHTKFNFHLRQL
HHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHH
KKAGLVMQNENKLYILTNTGQHVLTNHNISQD
HHCCCEEECCCEEEEEECCCCEEEECCCCCCC
>Mature Secondary Structure
MITILLAEDDVELRLNMVEILELEGFSVTAVESAEAAIRVSEKQHFDIALMDLLMAGMTG
CEEEEEECCCCEEEEEHHHEEEECCCEEEEECCCCCEEEECCCCCCHHHHHHHHHHCCHH
VEAISNLRQNQPLIAVIIITAYATVDTAVDAMKKGADSVMTKPFKSNELIVTIRRSLAEK
HHHHHHHHCCCCEEEEEEEEHHHHHHHHHHHHHCCHHHHHCCCCCCCCEEEEEHHHHHHH
QLFKSRVDLDPDLVYSALANPYRRKSLKVLATHKAVKFMDLCRLVEIEDHTKFNFHLRQL
HHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHH
KKAGLVMQNENKLYILTNTGQHVLTNHNISQD
HHCCCEEECCCEEEEEECCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1899859; 1738315; 10984043; 9473053 [H]