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The map label for this gene is alr [H]

Identifier: 167625575

GI number: 167625575

Start: 4470117

End: 4471193

Strand: Reverse

Name: alr [H]

Synonym: Shal_3669

Alternate gene names: 167625575

Gene position: 4471193-4470117 (Counterclockwise)

Preceding gene: 167625576

Following gene: 167625574

Centisome position: 85.54

GC content: 47.91

Gene sequence:

>1077_bases
TTGAAACCATTCCCACGAGCAGAAATTAGTCGCCACGCATTAAAGAATAATTTGGCCAGACTTCATGAACTTGCCCCATC
GAGTAAAGTGATGGCGGTTGTTAAAGCTAATGGCTATGGTCATGGCTTACTCAATGTGGCTCAATGTTTAGATAATGCCG
ATGGTTTTGGTTTAGCCCGCCTCGAAGAAGCATTAGCGCTTCGTGCTGGCGGTGTTAAAGCCAAGCTTTTATTATTGGAA
GGCTTTTTCCGCGCAGCCGATTTAGTCACCTTAGTTGAGCATGATATTGAGACTGTGGTTCATCATGAGTCGCAAATCGA
AATGCTCGAGCAAGCAGAGTTGAACAAACCCGTCACCGTATGGATGAAAATTGACTCAGGTATGCATCGACTCGGGTTTG
TGCCTGATGAGTTTAAGGTGGTTTATCAGCGCTTACTTGACTGTGATAATGTCGCCAAGCCAATTAATTTGATGACCCAC
TTTGCCTGCGCTGATGAGCCGAGTAATCCATACACTGCTGAGCAGTTAGCGGTTTTCGAAGCGCTAACGAAAGACCTGCC
AGGCGATCGCACTCTAGCCAATTCCGCAGGCGCTCTGTTTTGGCAACAAAGCCAAGCAAATTGGATCCGCCCCGGTATAG
CGCTTTATGGTGTCTCTCCTGTCGTTGGAGATCTGGGGACTAAGCATGGGCTTATTCCAGCGATGGAGCTTGTGTCGCAA
TTGATTGCCATTCGTGACCATAAGGCTGGTCAACCCGTCGGTTATGCTAGTTATTGGACTGCTGATAAAGATACCAAGCT
CGGTGTCGTTGCTATCGGCTACGGTGATGGTTATCCACGAAATGCGCCATTGGGCACACCGGTATTAATTAATGGTCGAT
TGGCACCTATCGTTGGCCGCGTTTCGATGGACATGCTGACCGTTGACCTAGGAGCTGATGCTAAAGATAGCGTTGGTGAT
AAAGCTGTGCTTTGGGGCAAAGAACTTCCAGTAGAGGAGGTTGCAGAGCATATAGGGACTATCGCCTACGAGCTTGTTAC
TAAATTAACACCGCGAGTCGCAGTTTGCCTAGATTGA

Upstream 100 bases:

>100_bases
AAGATTAATTATTGTCCATAAAGGCATTTAAGGACCATGATTAAATACAATAGAGCCTCAATGAGGCTCTTATTTTTAGA
TTAGATAGACAAGGTTACTT

Downstream 100 bases:

>100_bases
GCAAATAAACAACTTATTCTGTAGTGGTGATTGAGGCAGGATGCCCTTTACCAGAATGAAGAACGCTTACATTGAACATT
AATTTTAACTGCGCATTTAT

Product: alanine racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 358; Mature: 358

Protein sequence:

>358_residues
MKPFPRAEISRHALKNNLARLHELAPSSKVMAVVKANGYGHGLLNVAQCLDNADGFGLARLEEALALRAGGVKAKLLLLE
GFFRAADLVTLVEHDIETVVHHESQIEMLEQAELNKPVTVWMKIDSGMHRLGFVPDEFKVVYQRLLDCDNVAKPINLMTH
FACADEPSNPYTAEQLAVFEALTKDLPGDRTLANSAGALFWQQSQANWIRPGIALYGVSPVVGDLGTKHGLIPAMELVSQ
LIAIRDHKAGQPVGYASYWTADKDTKLGVVAIGYGDGYPRNAPLGTPVLINGRLAPIVGRVSMDMLTVDLGADAKDSVGD
KAVLWGKELPVEEVAEHIGTIAYELVTKLTPRVAVCLD

Sequences:

>Translated_358_residues
MKPFPRAEISRHALKNNLARLHELAPSSKVMAVVKANGYGHGLLNVAQCLDNADGFGLARLEEALALRAGGVKAKLLLLE
GFFRAADLVTLVEHDIETVVHHESQIEMLEQAELNKPVTVWMKIDSGMHRLGFVPDEFKVVYQRLLDCDNVAKPINLMTH
FACADEPSNPYTAEQLAVFEALTKDLPGDRTLANSAGALFWQQSQANWIRPGIALYGVSPVVGDLGTKHGLIPAMELVSQ
LIAIRDHKAGQPVGYASYWTADKDTKLGVVAIGYGDGYPRNAPLGTPVLINGRLAPIVGRVSMDMLTVDLGADAKDSVGD
KAVLWGKELPVEEVAEHIGTIAYELVTKLTPRVAVCLD
>Mature_358_residues
MKPFPRAEISRHALKNNLARLHELAPSSKVMAVVKANGYGHGLLNVAQCLDNADGFGLARLEEALALRAGGVKAKLLLLE
GFFRAADLVTLVEHDIETVVHHESQIEMLEQAELNKPVTVWMKIDSGMHRLGFVPDEFKVVYQRLLDCDNVAKPINLMTH
FACADEPSNPYTAEQLAVFEALTKDLPGDRTLANSAGALFWQQSQANWIRPGIALYGVSPVVGDLGTKHGLIPAMELVSQ
LIAIRDHKAGQPVGYASYWTADKDTKLGVVAIGYGDGYPRNAPLGTPVLINGRLAPIVGRVSMDMLTVDLGADAKDSVGD
KAVLWGKELPVEEVAEHIGTIAYELVTKLTPRVAVCLD

Specific function: Provides the D-alanine required for cell wall biosynthesis [H]

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family [H]

Homologues:

Organism=Escherichia coli, GI1790487, Length=348, Percent_Identity=57.4712643678161, Blast_Score=419, Evalue=1e-118,
Organism=Escherichia coli, GI1787439, Length=352, Percent_Identity=42.8977272727273, Blast_Score=276, Evalue=1e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- InterPro:   IPR020622 [H]

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N [H]

EC number: =5.1.1.1 [H]

Molecular weight: Translated: 38797; Mature: 38797

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: PS00395 ALANINE_RACEMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPFPRAEISRHALKNNLARLHELAPSSKVMAVVKANGYGHGLLNVAQCLDNADGFGLAR
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHCCCCCCCHHH
LEEALALRAGGVKAKLLLLEGFFRAADLVTLVEHDIETVVHHESQIEMLEQAELNKPVTV
HHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
WMKIDSGMHRLGFVPDEFKVVYQRLLDCDNVAKPINLMTHFACADEPSNPYTAEQLAVFE
EEEECCCCHHHCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
ALTKDLPGDRTLANSAGALFWQQSQANWIRPGIALYGVSPVVGDLGTKHGLIPAMELVSQ
HHHHCCCCCCHHHCCCCCEEEECCCCCCCCCCEEEEECCHHHHHCCCCCCCHHHHHHHHH
LIAIRDHKAGQPVGYASYWTADKDTKLGVVAIGYGDGYPRNAPLGTPVLINGRLAPIVGR
HHHHHCCCCCCCCCCCEEECCCCCCCEEEEEEECCCCCCCCCCCCCCEEECCCHHHHHHH
VSMDMLTVDLGADAKDSVGDKAVLWGKELPVEEVAEHIGTIAYELVTKLTPRVAVCLD
HEEEEEEEECCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEC
>Mature Secondary Structure
MKPFPRAEISRHALKNNLARLHELAPSSKVMAVVKANGYGHGLLNVAQCLDNADGFGLAR
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHCCCCCCCHHH
LEEALALRAGGVKAKLLLLEGFFRAADLVTLVEHDIETVVHHESQIEMLEQAELNKPVTV
HHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
WMKIDSGMHRLGFVPDEFKVVYQRLLDCDNVAKPINLMTHFACADEPSNPYTAEQLAVFE
EEEECCCCHHHCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
ALTKDLPGDRTLANSAGALFWQQSQANWIRPGIALYGVSPVVGDLGTKHGLIPAMELVSQ
HHHHCCCCCCHHHCCCCCEEEECCCCCCCCCCEEEEECCHHHHHCCCCCCCHHHHHHHHH
LIAIRDHKAGQPVGYASYWTADKDTKLGVVAIGYGDGYPRNAPLGTPVLINGRLAPIVGR
HHHHHCCCCCCCCCCCEEECCCCCCCEEEEEEECCCCCCCCCCCCCCEEECCCHHHHHHH
VSMDMLTVDLGADAKDSVGDKAVLWGKELPVEEVAEHIGTIAYELVTKLTPRVAVCLD
HEEEEEEEECCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA