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The map label for this gene is hflX [H]

Identifier: 167625539

GI number: 167625539

Start: 4429797

End: 4431092

Strand: Reverse

Name: hflX [H]

Synonym: Shal_3633

Alternate gene names: 167625539

Gene position: 4431092-4429797 (Counterclockwise)

Preceding gene: 167625540

Following gene: 167625538

Centisome position: 84.77

GC content: 46.99

Gene sequence:

>1296_bases
TTGTTTGATCGTTATGAGGCGGGAGAGAAAGCGGTACTTGTCCATATCGACTTTGCAGATGAGAAAAACCGTGAAGACTT
AGATGAGTTGAAGCTTCTAGTTGAATCGGCTGGTGCTCAGTCTATTGGAGTGATCTCTGGAAGTCGCCGCTCACCTGACC
GCAAGTTTTTTGTGGGTTCAGGTAAGGCTGAAGAATTAGCTGCGATGGTTGCGGCAACGGATGCCAATGTTGTGATTTTT
AATCACGCATTAAGTCCAGCTCAAGAGCGAAATCTTGAGCGGCTGTGTGAGTGCCGAGTGCTCGACAGAACGACTTTGAT
CTTGGATATTTTTGCTCAAAGAGCGAGGACATTCGAGGGTAAGTTACAGGTGGAGCTAGCGCAATTGCGCCACATGTCAA
CGCGCCTGATCAGAGGCTGGACGCATCTAGAGCGTCAAAAAGGTGGTATTGGTCTTCGTGGGCCCGGCGAAACTCAATTA
GAAACCGATAGGCGTCTATTGAGAGGCCGGATCAGCACGATCAATCGTCGTTTAGCAAAAGTTGATAAGCAGCGAGATCA
GAGTCGTAGAGCACGACAACGAAGCGATATGTCAACCGTGTCTTTGGTGGGTTACACCAACGCAGGTAAGTCGACGTTAT
TTAACGGATTGACGACATCTGATGTGTACGCTGCAGATCAGCTGTTTGCGACGTTGGATCCAACACTGCGTAAGCTAGAT
TTGCCGGATGGTGCGGTTATTCTTGCCGATACCGTTGGCTTTATTAGGCATTTACCCCATGATTTAGTTGCAGCTTTTAA
GGCAACACTGCAAGAAACACGACAGGCAGATCTACTTCTGCATGTTGTCGATAGTGCAGATGAAAAAATGGGTGATAACT
TTAAGCAGGTTCAAAACGTGCTTAAAGAGATCGATGCTATAGAGATTCCACAGTTGATCGTATGCAATAAAATCGATCTA
TTGGATGAGGTAAAACCTCGCATCGACTACGATGATGAGGGGACACCGATTAGAGTCTGGGTTTCTGCTCAGCAGCACAA
AGGCTTGGAATTAGTTGAAGAGGCGATAAACCAACTTGTTGGTAAGGCGATTCTGGAGCTAACCTTGCAAATCCCAGCTT
CGGCGGGGCATTATCTCGGTCAGTTTTATAAACTGGATGTAATACAGCAGAAAGAGTATGACGATCTGGGGGACTGTATT
ATTTCTGTTCGCTTGTTGGAGGCCGATTGGCGCCGACTCGTAAAACAGAGCCAAGGTGAAATAGAGACTTTTGTCGTCGA
CCCTGTCGTCGCATAA

Upstream 100 bases:

>100_bases
CATTTAACGTGAGCAACCACCAAGCGACAAATGCTCAAGCTGGCTTTAACGCACAGCATGACGATGGCGACGACAAGTAA
TTTGTTAAGGAGATTGCTTT

Downstream 100 bases:

>100_bases
TTAAGTATTTTAGTAATCTCGTTTATTTCATACACTTATGGAGTACTAAATGGCTTGGAACGAGCCCGGTAACAAGGGTC
AAGACCCTTGGGGAAATAAG

Product: GTP1/OBG protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 431; Mature: 431

Protein sequence:

>431_residues
MFDRYEAGEKAVLVHIDFADEKNREDLDELKLLVESAGAQSIGVISGSRRSPDRKFFVGSGKAEELAAMVAATDANVVIF
NHALSPAQERNLERLCECRVLDRTTLILDIFAQRARTFEGKLQVELAQLRHMSTRLIRGWTHLERQKGGIGLRGPGETQL
ETDRRLLRGRISTINRRLAKVDKQRDQSRRARQRSDMSTVSLVGYTNAGKSTLFNGLTTSDVYAADQLFATLDPTLRKLD
LPDGAVILADTVGFIRHLPHDLVAAFKATLQETRQADLLLHVVDSADEKMGDNFKQVQNVLKEIDAIEIPQLIVCNKIDL
LDEVKPRIDYDDEGTPIRVWVSAQQHKGLELVEEAINQLVGKAILELTLQIPASAGHYLGQFYKLDVIQQKEYDDLGDCI
ISVRLLEADWRRLVKQSQGEIETFVVDPVVA

Sequences:

>Translated_431_residues
MFDRYEAGEKAVLVHIDFADEKNREDLDELKLLVESAGAQSIGVISGSRRSPDRKFFVGSGKAEELAAMVAATDANVVIF
NHALSPAQERNLERLCECRVLDRTTLILDIFAQRARTFEGKLQVELAQLRHMSTRLIRGWTHLERQKGGIGLRGPGETQL
ETDRRLLRGRISTINRRLAKVDKQRDQSRRARQRSDMSTVSLVGYTNAGKSTLFNGLTTSDVYAADQLFATLDPTLRKLD
LPDGAVILADTVGFIRHLPHDLVAAFKATLQETRQADLLLHVVDSADEKMGDNFKQVQNVLKEIDAIEIPQLIVCNKIDL
LDEVKPRIDYDDEGTPIRVWVSAQQHKGLELVEEAINQLVGKAILELTLQIPASAGHYLGQFYKLDVIQQKEYDDLGDCI
ISVRLLEADWRRLVKQSQGEIETFVVDPVVA
>Mature_431_residues
MFDRYEAGEKAVLVHIDFADEKNREDLDELKLLVESAGAQSIGVISGSRRSPDRKFFVGSGKAEELAAMVAATDANVVIF
NHALSPAQERNLERLCECRVLDRTTLILDIFAQRARTFEGKLQVELAQLRHMSTRLIRGWTHLERQKGGIGLRGPGETQL
ETDRRLLRGRISTINRRLAKVDKQRDQSRRARQRSDMSTVSLVGYTNAGKSTLFNGLTTSDVYAADQLFATLDPTLRKLD
LPDGAVILADTVGFIRHLPHDLVAAFKATLQETRQADLLLHVVDSADEKMGDNFKQVQNVLKEIDAIEIPQLIVCNKIDL
LDEVKPRIDYDDEGTPIRVWVSAQQHKGLELVEEAINQLVGKAILELTLQIPASAGHYLGQFYKLDVIQQKEYDDLGDCI
ISVRLLEADWRRLVKQSQGEIETFVVDPVVA

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310133118, Length=269, Percent_Identity=34.5724907063197, Blast_Score=119, Evalue=7e-27,
Organism=Homo sapiens, GI310133116, Length=267, Percent_Identity=34.8314606741573, Blast_Score=118, Evalue=8e-27,
Organism=Homo sapiens, GI310124269, Length=249, Percent_Identity=35.3413654618474, Blast_Score=116, Evalue=4e-26,
Organism=Homo sapiens, GI310124267, Length=249, Percent_Identity=35.3413654618474, Blast_Score=116, Evalue=4e-26,
Organism=Homo sapiens, GI310124171, Length=249, Percent_Identity=35.3413654618474, Blast_Score=116, Evalue=4e-26,
Organism=Homo sapiens, GI310124169, Length=249, Percent_Identity=35.3413654618474, Blast_Score=116, Evalue=4e-26,
Organism=Escherichia coli, GI1790615, Length=426, Percent_Identity=62.6760563380282, Blast_Score=543, Evalue=1e-156,
Organism=Caenorhabditis elegans, GI17561038, Length=274, Percent_Identity=31.3868613138686, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24650079, Length=353, Percent_Identity=30.5949008498584, Blast_Score=110, Evalue=3e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 48359; Mature: 48359

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDRYEAGEKAVLVHIDFADEKNREDLDELKLLVESAGAQSIGVISGSRRSPDRKFFVGS
CCCCCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCEEEECC
GKAEELAAMVAATDANVVIFNHALSPAQERNLERLCECRVLDRTTLILDIFAQRARTFEG
CCHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
KLQVELAQLRHMSTRLIRGWTHLERQKGGIGLRGPGETQLETDRRLLRGRISTINRRLAK
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
VDKQRDQSRRARQRSDMSTVSLVGYTNAGKSTLFNGLTTSDVYAADQLFATLDPTLRKLD
HHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHCCCCCCHHHHHHHHHHHHCHHHHHCC
LPDGAVILADTVGFIRHLPHDLVAAFKATLQETRQADLLLHVVDSADEKMGDNFKQVQNV
CCCCCEEHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHH
LKEIDAIEIPQLIVCNKIDLLDEVKPRIDYDDEGTPIRVWVSAQQHKGLELVEEAINQLV
HHHCCCCCCCCEEECCCHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHH
GKAILELTLQIPASAGHYLGQFYKLDVIQQKEYDDLGDCIISVRLLEADWRRLVKQSQGE
HHHHHHHHHCCCCCCCHHHHHHHEEEHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
IETFVVDPVVA
EEEEEECCCCC
>Mature Secondary Structure
MFDRYEAGEKAVLVHIDFADEKNREDLDELKLLVESAGAQSIGVISGSRRSPDRKFFVGS
CCCCCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCEEEECC
GKAEELAAMVAATDANVVIFNHALSPAQERNLERLCECRVLDRTTLILDIFAQRARTFEG
CCHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
KLQVELAQLRHMSTRLIRGWTHLERQKGGIGLRGPGETQLETDRRLLRGRISTINRRLAK
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
VDKQRDQSRRARQRSDMSTVSLVGYTNAGKSTLFNGLTTSDVYAADQLFATLDPTLRKLD
HHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHCCCCCCHHHHHHHHHHHHCHHHHHCC
LPDGAVILADTVGFIRHLPHDLVAAFKATLQETRQADLLLHVVDSADEKMGDNFKQVQNV
CCCCCEEHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHH
LKEIDAIEIPQLIVCNKIDLLDEVKPRIDYDDEGTPIRVWVSAQQHKGLELVEEAINQLV
HHHCCCCCCCCEEECCCHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHH
GKAILELTLQIPASAGHYLGQFYKLDVIQQKEYDDLGDCIISVRLLEADWRRLVKQSQGE
HHHHHHHHHCCCCCCCHHHHHHHEEEHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
IETFVVDPVVA
EEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]