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The map label for this gene is betA [C]

Identifier: 167625503

GI number: 167625503

Start: 4391010

End: 4392605

Strand: Reverse

Name: betA [C]

Synonym: Shal_3597

Alternate gene names: 167625503

Gene position: 4392605-4391010 (Counterclockwise)

Preceding gene: 167625504

Following gene: 167625500

Centisome position: 84.04

GC content: 51.0

Gene sequence:

>1596_bases
GTGGCCATTGAAGATCCAATCGTAATTGGCTTAGATTCAGGCTGGGCACATATAAATGCCTCTAAGCTCACCGAAAACCA
ATCCTTAGAGGCCGATGTCGTCATTGTTGGTAGTGGCGCGGGCGGCGGTGTCGCGGCAGAAATTCTGACAGAGGCAGGCC
TGTCGGTGATTATCGTCGAGGGGGGGGCGCTTAAGTCTTCGAAAGACTTTGTCATGGAGGAGCGAGTCGCCTATCCCGAC
CTCTACCAACAAGCGGCGGGTATGAAGACCACAGATAAGGCCATTGGCATATTTCAGGGGCGCGCGGTGGGCGGTTCAAC
TACGGTTAACTGGACCACCTCTATTCGCACACCTGAGCCTGCTCTTGAATATTGGGCCAAAACGAAATCCGTTACAGGCC
TTTCTCGCTCAGAGCTTGACCCTTGGTTTGAGAAGATGGAGCAGCGACTCAATATCAGCAAGTGGGCCTATGAGCCTAAC
CGTAATAACCAAGCATTAAAGCAGGGCTGCGAACAGCTCGGTTGGGATTACACTGTGATTAAGCGCAATGTGCTTGGCTG
TTGGAATACGGGATATTGCGGCATGGGCTGCCCGGTAAACGCTAAACAGTCCATGTTGGTCACCACCATCCCCGCGGCCC
TCGAACGTGGGGCCACATTGGTGAGTCAAGCTCAAGTCATTAAGCTTGAGTATCACAACGACAAGATTTTTGCGGTTAAA
GCCCAAGCGGTCGACAAAAAGATGAAACCCTTGCCAGTCGAAGTCATGTTTAAGGCTAAGCATTATATCTTGGCCGCAGG
TGCCATTCATACGCCGACCATCATGTTACGCTCTAAACTTCCCGATCCACATGAGGTTATAGGTAAGCGTACTTTCTTGC
ATCCGACCTTGTTGAGTGGCGCGGTGTTTAGCGACCCGATTAATGGCCACAGCGGTGCGCCTCAGTCTATCTATTCCGAT
GAATTTGTCTGGCAGAATAGCGCCGATGGTGAGCTAGGCTATAAACTCGAAGTCCCGCCAATTCATCCGATTTTGATCGC
CTCAAAAACTATTGGTTACGGTAAAAGTCACGCACACTTGATGGAAAAGTTTAATCAATTACAGGTGACTATTGCCCTAG
TGAGAGATGGCTATCATGAAAATAGCCAAGGCGGGCAGGTCAAGCTAACCGAGTATGGCAGCACCTTAGATTACCCGCTC
ACCGATGCATTTTGGCGTGCAGCAAGGCGAGCCTATGCCAGTATGGCCGAGCTGCAGTTTGCCGCAGGCGCGCAGCAAGT
ACTGCCGATTAGCGAGGGGATGCCCTATCTGTCGAGCTGGAAAGAGGCCAAAAAAGCCATTAAGGATATGGAGCTGGCGC
CACTTAAAACCGTTGTTGCATCGGCGCATGTCATGGGCGGCTGCCCTATGGGAGAAGACCCAAAATTATCTATGGTTAAC
AGTTTCGGCGAGTCTCACTATTTCGAAAACTTATCGGTGATGGACGGCTCGATATTCCCGACCAGCTTAGGGGCAAACCC
GCAGCTATCTATCTATGGCATTACCGCAAGAAACGCGACTCGGCTAGCAGAGAAGCTTAAGCCCAAACCTAATTAA

Upstream 100 bases:

>100_bases
GAGTCGATTGCATTATGCTAAGCCGACGTTCCTTGAAGATATGAACTCTTGAGGATATGAAGTGATGTTATTAATAAACA
CTATGGGGAAGGGGTAGCTT

Downstream 100 bases:

>100_bases
TCAACAGAAAACATGAACCCAGCACAAACTGGGTTCTTTGCTTTAAAAGCGATAAACCACGAAGTGTTTACTTCATTTGC
TACACAGAGGACACGAAGAA

Product: glucose-methanol-choline oxidoreductase

Products: Betaine Aldehyde; Reduced Acceptor. [C]

Alternate protein names: NA

Number of amino acids: Translated: 531; Mature: 530

Protein sequence:

>531_residues
MAIEDPIVIGLDSGWAHINASKLTENQSLEADVVIVGSGAGGGVAAEILTEAGLSVIIVEGGALKSSKDFVMEERVAYPD
LYQQAAGMKTTDKAIGIFQGRAVGGSTTVNWTTSIRTPEPALEYWAKTKSVTGLSRSELDPWFEKMEQRLNISKWAYEPN
RNNQALKQGCEQLGWDYTVIKRNVLGCWNTGYCGMGCPVNAKQSMLVTTIPAALERGATLVSQAQVIKLEYHNDKIFAVK
AQAVDKKMKPLPVEVMFKAKHYILAAGAIHTPTIMLRSKLPDPHEVIGKRTFLHPTLLSGAVFSDPINGHSGAPQSIYSD
EFVWQNSADGELGYKLEVPPIHPILIASKTIGYGKSHAHLMEKFNQLQVTIALVRDGYHENSQGGQVKLTEYGSTLDYPL
TDAFWRAARRAYASMAELQFAAGAQQVLPISEGMPYLSSWKEAKKAIKDMELAPLKTVVASAHVMGGCPMGEDPKLSMVN
SFGESHYFENLSVMDGSIFPTSLGANPQLSIYGITARNATRLAEKLKPKPN

Sequences:

>Translated_531_residues
MAIEDPIVIGLDSGWAHINASKLTENQSLEADVVIVGSGAGGGVAAEILTEAGLSVIIVEGGALKSSKDFVMEERVAYPD
LYQQAAGMKTTDKAIGIFQGRAVGGSTTVNWTTSIRTPEPALEYWAKTKSVTGLSRSELDPWFEKMEQRLNISKWAYEPN
RNNQALKQGCEQLGWDYTVIKRNVLGCWNTGYCGMGCPVNAKQSMLVTTIPAALERGATLVSQAQVIKLEYHNDKIFAVK
AQAVDKKMKPLPVEVMFKAKHYILAAGAIHTPTIMLRSKLPDPHEVIGKRTFLHPTLLSGAVFSDPINGHSGAPQSIYSD
EFVWQNSADGELGYKLEVPPIHPILIASKTIGYGKSHAHLMEKFNQLQVTIALVRDGYHENSQGGQVKLTEYGSTLDYPL
TDAFWRAARRAYASMAELQFAAGAQQVLPISEGMPYLSSWKEAKKAIKDMELAPLKTVVASAHVMGGCPMGEDPKLSMVN
SFGESHYFENLSVMDGSIFPTSLGANPQLSIYGITARNATRLAEKLKPKPN
>Mature_530_residues
AIEDPIVIGLDSGWAHINASKLTENQSLEADVVIVGSGAGGGVAAEILTEAGLSVIIVEGGALKSSKDFVMEERVAYPDL
YQQAAGMKTTDKAIGIFQGRAVGGSTTVNWTTSIRTPEPALEYWAKTKSVTGLSRSELDPWFEKMEQRLNISKWAYEPNR
NNQALKQGCEQLGWDYTVIKRNVLGCWNTGYCGMGCPVNAKQSMLVTTIPAALERGATLVSQAQVIKLEYHNDKIFAVKA
QAVDKKMKPLPVEVMFKAKHYILAAGAIHTPTIMLRSKLPDPHEVIGKRTFLHPTLLSGAVFSDPINGHSGAPQSIYSDE
FVWQNSADGELGYKLEVPPIHPILIASKTIGYGKSHAHLMEKFNQLQVTIALVRDGYHENSQGGQVKLTEYGSTLDYPLT
DAFWRAARRAYASMAELQFAAGAQQVLPISEGMPYLSSWKEAKKAIKDMELAPLKTVVASAHVMGGCPMGEDPKLSMVNS
FGESHYFENLSVMDGSIFPTSLGANPQLSIYGITARNATRLAEKLKPKPN

Specific function: Can Catalyze The Oxidation Of Choline To Betaine Aldehyde And Betaine Aldehyde To Glycine Betaine At The Same Rate. [C]

COG id: COG2303

COG function: function code E; Choline dehydrogenase and related flavoproteins

Gene ontology:

Cell location: Membrane-Bound [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GMC oxidoreductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000172
- InterPro:   IPR007867 [H]

Pfam domain/function: PF05199 GMC_oxred_C; PF00732 GMC_oxred_N [H]

EC number: 1.1.99.1 [C]

Molecular weight: Translated: 57830; Mature: 57699

Theoretical pI: Translated: 7.40; Mature: 7.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIEDPIVIGLDSGWAHINASKLTENQSLEADVVIVGSGAGGGVAAEILTEAGLSVIIVE
CCCCCCEEEEECCCCEEEEHHHCCCCCCCCEEEEEEECCCCCCHHHHHHHHCCCEEEEEE
GGALKSSKDFVMEERVAYPDLYQQAAGMKTTDKAIGIFQGRAVGGSTTVNWTTSIRTPEP
CCCCCCCHHHHHHHHCCCHHHHHHHCCCCCCCHHHEEEECCCCCCCCEEEEEEECCCCCH
ALEYWAKTKSVTGLSRSELDPWFEKMEQRLNISKWAYEPNRNNQALKQGCEQLGWDYTVI
HHHHHHHHCCCCCCCHHHCCHHHHHHHHHCCHHHEECCCCCCCHHHHHHHHHHCCCEEEE
KRNVLGCWNTGYCGMGCPVNAKQSMLVTTIPAALERGATLVSQAQVIKLEYHNDKIFAVK
HHCCCCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHCCCHHHCCEEEEEEEECCCEEEEEE
AQAVDKKMKPLPVEVMFKAKHYILAAGAIHTPTIMLRSKLPDPHEVIGKRTFLHPTLLSG
EHHHCCCCCCCCCEEEEECCEEEEEECCCCCCEEEEECCCCCHHHHHCCHHEECHHHHCC
AVFSDPINGHSGAPQSIYSDEFVWQNSADGELGYKLEVPPIHPILIASKTIGYGKSHAHL
CCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCEEEECCCCCEEEEEECCCCCCCHHHHH
MEKFNQLQVTIALVRDGYHENSQGGQVKLTEYGSTLDYPLTDAFWRAARRAYASMAELQF
HHHHHHHEEEEEEEECCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHH
AAGAQQVLPISEGMPYLSSWKEAKKAIKDMELAPLKTVVASAHVMGGCPMGEDPKLSMVN
HCCCCCEEECCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHH
SFGESHYFENLSVMDGSIFPTSLGANPQLSIYGITARNATRLAEKLKPKPN
HCCHHHHHCCCEECCCCCCCCCCCCCCEEEEEEEECCCHHHHHHHCCCCCC
>Mature Secondary Structure 
AIEDPIVIGLDSGWAHINASKLTENQSLEADVVIVGSGAGGGVAAEILTEAGLSVIIVE
CCCCCEEEEECCCCEEEEHHHCCCCCCCCEEEEEEECCCCCCHHHHHHHHCCCEEEEEE
GGALKSSKDFVMEERVAYPDLYQQAAGMKTTDKAIGIFQGRAVGGSTTVNWTTSIRTPEP
CCCCCCCHHHHHHHHCCCHHHHHHHCCCCCCCHHHEEEECCCCCCCCEEEEEEECCCCCH
ALEYWAKTKSVTGLSRSELDPWFEKMEQRLNISKWAYEPNRNNQALKQGCEQLGWDYTVI
HHHHHHHHCCCCCCCHHHCCHHHHHHHHHCCHHHEECCCCCCCHHHHHHHHHHCCCEEEE
KRNVLGCWNTGYCGMGCPVNAKQSMLVTTIPAALERGATLVSQAQVIKLEYHNDKIFAVK
HHCCCCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHCCCHHHCCEEEEEEEECCCEEEEEE
AQAVDKKMKPLPVEVMFKAKHYILAAGAIHTPTIMLRSKLPDPHEVIGKRTFLHPTLLSG
EHHHCCCCCCCCCEEEEECCEEEEEECCCCCCEEEEECCCCCHHHHHCCHHEECHHHHCC
AVFSDPINGHSGAPQSIYSDEFVWQNSADGELGYKLEVPPIHPILIASKTIGYGKSHAHL
CCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCEEEECCCCCEEEEEECCCCCCCHHHHH
MEKFNQLQVTIALVRDGYHENSQGGQVKLTEYGSTLDYPLTDAFWRAARRAYASMAELQF
HHHHHHHEEEEEEEECCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHH
AAGAQQVLPISEGMPYLSSWKEAKKAIKDMELAPLKTVVASAHVMGGCPMGEDPKLSMVN
HCCCCCEEECCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHH
SFGESHYFENLSVMDGSIFPTSLGANPQLSIYGITARNATRLAEKLKPKPN
HCCHHHHHCCCEECCCCCCCCCCCCCCEEEEEEEECCCHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Coenzyme Q [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): 7 {choline}} 1.1 {phenazine}} [C]

Substrates: Choline; Acceptor [C]

Specific reaction: Choline + Acceptor = Betaine Aldehyde + Reduced Acceptor. [C]

General reaction: Redox reaction [C]

Inhibitor: 2-Dimethylaminoethanol; Betaine aldehyde; Monoethanolamine; Semicarbazide [C]

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]