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The map label for this gene is cobC [H]

Identifier: 167625372

GI number: 167625372

Start: 4215566

End: 4216213

Strand: Reverse

Name: cobC [H]

Synonym: Shal_3461

Alternate gene names: 167625372

Gene position: 4216213-4215566 (Counterclockwise)

Preceding gene: 167625383

Following gene: 167625371

Centisome position: 80.66

GC content: 48.61

Gene sequence:

>648_bases
ATGATGCAAACCACTAAGGTGATTTTACTTCGACATGGTGAATGTGAGGGCGGCAATATTTTACGCGGTCAAGTCGATGT
GGCCTTAACTGGGCAGGGTGAACAGCAGATGCGAAAGGCGTTTTCTGCGCTGAGTTTAGTATCGTTTCAGTCTGAAGCCG
AGCCAGAATTAGCGGCACCGCAAGCGCCTGAAGTGGTGTTGAGTTCACCGCTTATTCGCTGCGCTACAATGGCAGGGAGG
TTTGCACTGTTAAACCAGTTACCTTACTCAGTCGAAGCTGGGTTTAGAGAGCTGAATTTTGGCGACTGGGATGGACAAAC
ATTTGATACTCTCTATCAGAACTATGCTCATGAACTTGATAACTATTGGGCTAATCCTTGGTTATTACCACCGCCCAATG
GCGAGTCGATGCAGGCGTTTGAGTCTCGTATCGATACGGCTTGGCAGACGATGCTTAAGCAGCATCAAGGTAAGCGCGTA
CTGCTGGTAACTCACGGCGGCGTGATCCGTCATTTGATGGCCAAAGCGTTAGGTGTCAATCAAGCAGCGGGTTTTTATAC
TTCGCTTAAATTGTCCTATGCCGCCACGGTAGAGATTGATGTTTTGCATGATGGCGAGCAGCAGTACATGACCCTTAATT
GGCGGTAA

Upstream 100 bases:

>100_bases
AGGCGATAAAAAGTGCAAGTGCTAAAGCATGATACTTTTTCAGCATTAAAACCCAATGAATTTTAACTAAGTGTCTGATA
AATAATGAAGGTGTGCGGGG

Downstream 100 bases:

>100_bases
AGAAGGAGCTAGGGTTAAGAGAAGATTCTAGGTTTCAAAGAAGGTACTAGCTCATAGGAAAAGCAGGTCCTAGGAAAAGC
AAAAACGGAAAAGCTGAAAC

Product: phosphoglycerate mutase

Products: NA

Alternate protein names: Alpha-ribazole-5'-phosphate phosphatase [H]

Number of amino acids: Translated: 215; Mature: 215

Protein sequence:

>215_residues
MMQTTKVILLRHGECEGGNILRGQVDVALTGQGEQQMRKAFSALSLVSFQSEAEPELAAPQAPEVVLSSPLIRCATMAGR
FALLNQLPYSVEAGFRELNFGDWDGQTFDTLYQNYAHELDNYWANPWLLPPPNGESMQAFESRIDTAWQTMLKQHQGKRV
LLVTHGGVIRHLMAKALGVNQAAGFYTSLKLSYAATVEIDVLHDGEQQYMTLNWR

Sequences:

>Translated_215_residues
MMQTTKVILLRHGECEGGNILRGQVDVALTGQGEQQMRKAFSALSLVSFQSEAEPELAAPQAPEVVLSSPLIRCATMAGR
FALLNQLPYSVEAGFRELNFGDWDGQTFDTLYQNYAHELDNYWANPWLLPPPNGESMQAFESRIDTAWQTMLKQHQGKRV
LLVTHGGVIRHLMAKALGVNQAAGFYTSLKLSYAATVEIDVLHDGEQQYMTLNWR
>Mature_215_residues
MMQTTKVILLRHGECEGGNILRGQVDVALTGQGEQQMRKAFSALSLVSFQSEAEPELAAPQAPEVVLSSPLIRCATMAGR
FALLNQLPYSVEAGFRELNFGDWDGQTFDTLYQNYAHELDNYWANPWLLPPPNGESMQAFESRIDTAWQTMLKQHQGKRV
LLVTHGGVIRHLMAKALGVNQAAGFYTSLKLSYAATVEIDVLHDGEQQYMTLNWR

Specific function: Converts N1-(5-phospho-alpha-D-ribosyl)-5,6- dimethylbenzimidazole into N1-alpha-D-ribosyl-5,6- dimethylbenzimidazole; involved in the assembly of the nucleotide loop of cobalamin [H]

COG id: COG0406

COG function: function code G; Fructose-2,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family [H]

Homologues:

Organism=Escherichia coli, GI1786857, Length=212, Percent_Identity=26.8867924528302, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR001345
- InterPro:   IPR017578 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: =3.1.3.73 [H]

Molecular weight: Translated: 24030; Mature: 24030

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMQTTKVILLRHGECEGGNILRGQVDVALTGQGEQQMRKAFSALSLVSFQSEAEPELAAP
CCCCEEEEEEECCCCCCCCEEEEEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCC
QAPEVVLSSPLIRCATMAGRFALLNQLPYSVEAGFRELNFGDWDGQTFDTLYQNYAHELD
CCCHHHHHCHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHH
NYWANPWLLPPPNGESMQAFESRIDTAWQTMLKQHQGKRVLLVTHGGVIRHLMAKALGVN
HHCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHCCC
QAAGFYTSLKLSYAATVEIDVLHDGEQQYMTLNWR
CCCCCEEEEEEEEEEEEEEEEEECCCCEEEEEECC
>Mature Secondary Structure
MMQTTKVILLRHGECEGGNILRGQVDVALTGQGEQQMRKAFSALSLVSFQSEAEPELAAP
CCCCEEEEEEECCCCCCCCEEEEEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCC
QAPEVVLSSPLIRCATMAGRFALLNQLPYSVEAGFRELNFGDWDGQTFDTLYQNYAHELD
CCCHHHHHCHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHH
NYWANPWLLPPPNGESMQAFESRIDTAWQTMLKQHQGKRVLLVTHGGVIRHLMAKALGVN
HHCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHCCC
QAAGFYTSLKLSYAATVEIDVLHDGEQQYMTLNWR
CCCCCEEEEEEEEEEEEEEEEEECCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]