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The map label for this gene is cobT

Identifier: 167625369

GI number: 167625369

Start: 4211783

End: 4212811

Strand: Reverse

Name: cobT

Synonym: Shal_3458

Alternate gene names: 167625369

Gene position: 4212811-4211783 (Counterclockwise)

Preceding gene: 167625370

Following gene: 167625368

Centisome position: 80.6

GC content: 48.69

Gene sequence:

>1029_bases
ATGTTCGATATTAAACTAATAAATACTGAATTTGACGATGTCATTCAGCAAAAAATTGACACAAAAACCAAACCCTTGGG
CGCTCTGGGCGACTTGGAAACCTTAGCGCTGCAAATCGCCCGTGTACTCGGTAAAGATAAACCCCAGATCCGTAATCCAA
AGATGATGGTATTTGCGGCCGACCACGGCATTGCAGATTCTGGCGTATCGATAGCACCGAGTGAAGTGACCACACAGATG
GTGGTTAACTTTATCAATGGCGGTGCGGCGATTAATGTATTTACTCGTCAAGTAGGTTTTGACTTAGAGGTGATAGATTG
CGGCATCTTAAAGCCGATTGAAAATCTAGAGGGCGTAATTGACCAGCGTTTAGGTGCGGGCACAGGGCCCATTCATAAAC
GTGCTGCCATGACCTTAGGCGCGGTGAAACAAGGCTTTAAGATGGCTACCGACAGAGTCGAGCTACACCATCAAAACGGT
TGTAACTTAATCGCCTTGGGTGAAATGGGCATTGGCAATACCTCGTCTGCGGCGGCAATTATGGCTGCGCTAACTGGAAT
GAAGGCAGAAGATTGTGTTGGCCGAGGCACAGGCATCGATGCGACAACCTTTAAGCGCAAGAAGATGTTAGTCGAGCAAG
CTCTGCTTATGCACCACTGTGAGCTTGATGACCCAATGCAGGTTCTGGCCTGTCTCGGCGGCTTTGAGATTGTGCAGATG
ACAGGCGCTATGTTGGCCGCTGCCGAGCGTAATATGCTGGTGATTGTCGATGGCTTTATCGCAACTGCAGCGGCATTAGC
GGCAATCAAGATTAACCCCAACGTGCGTGAGTATATGATTTTCGCTCATCAGTCAGATGAGAAGGGCCACGTTATGATGC
TGGAATTCTTGCAAGCTAAGCCGTTGTTAAAGCTTGGCATGAAACTGGGTGAAGGCACGGGGGCGGCATTGGCGCTCCCG
CTTATTCAAGCAGCGGTGAATTTCTATAATGAGATGGCCAGCTTTGCAGATGCAGGGATAGAGATTTAA

Upstream 100 bases:

>100_bases
ATTTTAGGTAGTCGCAGTGCCAAGCGCATCTAGCGAGCCATTGTAATAGTGATCGTTGTACGTACAACTCAACCTTATTA
AGCGGTTAAGGGAATCAAAT

Downstream 100 bases:

>100_bases
CTGCTGAAACAAGCTAAGACGGTCAAAGCCAAGACGGTTCAAGCCAAGACGGTCAAAGCTAAGACGGTTCAAGCCAAGAC
GGTCAAAGCTAAGACGGTCA

Product: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase

Products: NA

Alternate protein names: NN:DBI PRT; N(1)-alpha-phosphoribosyltransferase

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MFDIKLINTEFDDVIQQKIDTKTKPLGALGDLETLALQIARVLGKDKPQIRNPKMMVFAADHGIADSGVSIAPSEVTTQM
VVNFINGGAAINVFTRQVGFDLEVIDCGILKPIENLEGVIDQRLGAGTGPIHKRAAMTLGAVKQGFKMATDRVELHHQNG
CNLIALGEMGIGNTSSAAAIMAALTGMKAEDCVGRGTGIDATTFKRKKMLVEQALLMHHCELDDPMQVLACLGGFEIVQM
TGAMLAAAERNMLVIVDGFIATAAALAAIKINPNVREYMIFAHQSDEKGHVMMLEFLQAKPLLKLGMKLGEGTGAALALP
LIQAAVNFYNEMASFADAGIEI

Sequences:

>Translated_342_residues
MFDIKLINTEFDDVIQQKIDTKTKPLGALGDLETLALQIARVLGKDKPQIRNPKMMVFAADHGIADSGVSIAPSEVTTQM
VVNFINGGAAINVFTRQVGFDLEVIDCGILKPIENLEGVIDQRLGAGTGPIHKRAAMTLGAVKQGFKMATDRVELHHQNG
CNLIALGEMGIGNTSSAAAIMAALTGMKAEDCVGRGTGIDATTFKRKKMLVEQALLMHHCELDDPMQVLACLGGFEIVQM
TGAMLAAAERNMLVIVDGFIATAAALAAIKINPNVREYMIFAHQSDEKGHVMMLEFLQAKPLLKLGMKLGEGTGAALALP
LIQAAVNFYNEMASFADAGIEI
>Mature_342_residues
MFDIKLINTEFDDVIQQKIDTKTKPLGALGDLETLALQIARVLGKDKPQIRNPKMMVFAADHGIADSGVSIAPSEVTTQM
VVNFINGGAAINVFTRQVGFDLEVIDCGILKPIENLEGVIDQRLGAGTGPIHKRAAMTLGAVKQGFKMATDRVELHHQNG
CNLIALGEMGIGNTSSAAAIMAALTGMKAEDCVGRGTGIDATTFKRKKMLVEQALLMHHCELDDPMQVLACLGGFEIVQM
TGAMLAAAERNMLVIVDGFIATAAALAAIKINPNVREYMIFAHQSDEKGHVMMLEFLQAKPLLKLGMKLGEGTGAALALP
LIQAAVNFYNEMASFADAGIEI

Specific function: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)

COG id: COG2038

COG function: function code H; NaMN:DMB phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobT family

Homologues:

Organism=Escherichia coli, GI1788300, Length=329, Percent_Identity=37.9939209726444, Blast_Score=213, Evalue=1e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COBT_SHEHH (B0TT63)

Other databases:

- EMBL:   CP000931
- RefSeq:   YP_001675663.1
- ProteinModelPortal:   B0TT63
- SMR:   B0TT63
- GeneID:   5903642
- GenomeReviews:   CP000931_GR
- KEGG:   shl:Shal_3458
- HOGENOM:   HBG634399
- OMA:   NEMATFS
- ProtClustDB:   PRK00105
- BioCyc:   SHAL458817:SHAL_3458-MONOMER
- HAMAP:   MF_00230
- InterPro:   IPR003200
- InterPro:   IPR023195
- InterPro:   IPR017846
- Gene3D:   G3DSA:1.10.1610.10
- TIGRFAMs:   TIGR03160

Pfam domain/function: PF02277 DBI_PRT; SSF52733 NN:DBI_PRT

EC number: =2.4.2.21

Molecular weight: Translated: 36534; Mature: 36534

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: NA

Important sites: ACT_SITE 311-311

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
5.8 %Met     (Translated Protein)
7.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
5.8 %Met     (Mature Protein)
7.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDIKLINTEFDDVIQQKIDTKTKPLGALGDLETLALQIARVLGKDKPQIRNPKMMVFAA
CCEEEEECCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEEE
DHGIADSGVSIAPSEVTTQMVVNFINGGAAINVFTRQVGFDLEVIDCGILKPIENLEGVI
CCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEEHHHHCCCEEEECCCCCCHHHHHHHHH
DQRLGAGTGPIHKRAAMTLGAVKQGFKMATDRVELHHQNGCNLIALGEMGIGNTSSAAAI
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCEEEECCCCCCCCHHHHHH
MAALTGMKAEDCVGRGTGIDATTFKRKKMLVEQALLMHHCELDDPMQVLACLGGFEIVQM
HHHHHCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHH
TGAMLAAAERNMLVIVDGFIATAAALAAIKINPNVREYMIFAHQSDEKGHVMMLEFLQAK
HHHHHHHCCCCEEEEECCHHHHHHHHEEEEECCCCEEEEEEEECCCCCCCCHHHHHHHCC
PLLKLGMKLGEGTGAALALPLIQAAVNFYNEMASFADAGIEI
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MFDIKLINTEFDDVIQQKIDTKTKPLGALGDLETLALQIARVLGKDKPQIRNPKMMVFAA
CCEEEEECCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEEE
DHGIADSGVSIAPSEVTTQMVVNFINGGAAINVFTRQVGFDLEVIDCGILKPIENLEGVI
CCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEEHHHHCCCEEEECCCCCCHHHHHHHHH
DQRLGAGTGPIHKRAAMTLGAVKQGFKMATDRVELHHQNGCNLIALGEMGIGNTSSAAAI
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCEEEECCCCCCCCHHHHHH
MAALTGMKAEDCVGRGTGIDATTFKRKKMLVEQALLMHHCELDDPMQVLACLGGFEIVQM
HHHHHCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHH
TGAMLAAAERNMLVIVDGFIATAAALAAIKINPNVREYMIFAHQSDEKGHVMMLEFLQAK
HHHHHHHCCCCEEEEECCHHHHHHHHEEEEECCCCEEEEEEEECCCCCCCCHHHHHHHCC
PLLKLGMKLGEGTGAALALPLIQAAVNFYNEMASFADAGIEI
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA