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The map label for this gene is leuE [H]

Identifier: 167625304

GI number: 167625304

Start: 4137827

End: 4138441

Strand: Reverse

Name: leuE [H]

Synonym: Shal_3393

Alternate gene names: 167625304

Gene position: 4138441-4137827 (Counterclockwise)

Preceding gene: 167625307

Following gene: 167625300

Centisome position: 79.18

GC content: 49.92

Gene sequence:

>615_bases
ATGAGTATTAGCACTTGGCTAGGCTTGTTAGCAATTTGCTGTTTAGGCGCCATGTCACCGGGGCCAAGTTTGGCTATGGT
GGTGAGACACACCTTAGGTGGTGGTCGGGGAAAAGGGATTATCTGCGCTTGGGCGCACTCTATCGGTATTGGTATTTATG
CCCTAGTTACATTATTGGGGTTGGCGGTGCTGCTAAAGCAGGCGCCAATGGTATTTAATGGTATTGCGATTATCGGTGCG
CTTTATCTTGCCTATATGGGCATACAGGCGTTGCGATCCAAGGGGGGAATGTCAGATAAACTCGCAGCAGGCAAGCCTAC
GGATGCGTTTAGTGCGGCGAGAGATGGTCTGGCTATCTCCTTATTCAACCCTAAAATTATGCTGTTTTTCTTGGCGCTAT
TTAGCCAGTTTGTAATGGTTGCCGACAGCTTGACTGGTAAGGCCTTGATTGTGTTGACGCCACTGGTGGTTGACGGGCTT
TGGTATACGCTTATCGCCTTGGTATTGTCTCACGCCTCTGTGCTGCCTAAGCTAAGGGCAAAAGCGGCCCTTATCGATAA
GTTATCCGGTGTGGTACTGATCCTACTTGCGGTGCGGGTGGTTGTTACCCTCTAG

Upstream 100 bases:

>100_bases
CTCAATTATGCCCCCATAACGCAGATCGTGTATATTGTGGCGATTAAAGCGCTGAGTTAATTACGAAGTGTCATTATAAA
AACAATAATAGAGGAAAAAG

Downstream 100 bases:

>100_bases
CCTCCAGAGTTTGAATATCAACATTTACCCATAAAAAAACGCCATCTAAACAGATGGCGTTCTTATATCCATTAGCAGGC
AAGCTTCAATCAGAGAGCTT

Product: lysine exporter protein LysE/YggA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 204; Mature: 203

Protein sequence:

>204_residues
MSISTWLGLLAICCLGAMSPGPSLAMVVRHTLGGGRGKGIICAWAHSIGIGIYALVTLLGLAVLLKQAPMVFNGIAIIGA
LYLAYMGIQALRSKGGMSDKLAAGKPTDAFSAARDGLAISLFNPKIMLFFLALFSQFVMVADSLTGKALIVLTPLVVDGL
WYTLIALVLSHASVLPKLRAKAALIDKLSGVVLILLAVRVVVTL

Sequences:

>Translated_204_residues
MSISTWLGLLAICCLGAMSPGPSLAMVVRHTLGGGRGKGIICAWAHSIGIGIYALVTLLGLAVLLKQAPMVFNGIAIIGA
LYLAYMGIQALRSKGGMSDKLAAGKPTDAFSAARDGLAISLFNPKIMLFFLALFSQFVMVADSLTGKALIVLTPLVVDGL
WYTLIALVLSHASVLPKLRAKAALIDKLSGVVLILLAVRVVVTL
>Mature_203_residues
SISTWLGLLAICCLGAMSPGPSLAMVVRHTLGGGRGKGIICAWAHSIGIGIYALVTLLGLAVLLKQAPMVFNGIAIIGAL
YLAYMGIQALRSKGGMSDKLAAGKPTDAFSAARDGLAISLFNPKIMLFFLALFSQFVMVADSLTGKALIVLTPLVVDGLW
YTLIALVLSHASVLPKLRAKAALIDKLSGVVLILLAVRVVVTL

Specific function: Exporter of leucine [H]

COG id: COG1280

COG function: function code E; Putative threonine efflux protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI1788099, Length=185, Percent_Identity=28.1081081081081, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1786522, Length=179, Percent_Identity=26.8156424581006, Blast_Score=62, Evalue=2e-11,
Organism=Escherichia coli, GI48994978, Length=200, Percent_Identity=27, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 21272; Mature: 21141

Theoretical pI: Translated: 10.47; Mature: 10.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSISTWLGLLAICCLGAMSPGPSLAMVVRHTLGGGRGKGIICAWAHSIGIGIYALVTLLG
CCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHH
LAVLLKQAPMVFNGIAIIGALYLAYMGIQALRSKGGMSDKLAAGKPTDAFSAARDGLAIS
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHCCCEEE
LFNPKIMLFFLALFSQFVMVADSLTGKALIVLTPLVVDGLWYTLIALVLSHASVLPKLRA
EECHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KAALIDKLSGVVLILLAVRVVVTL
HHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SISTWLGLLAICCLGAMSPGPSLAMVVRHTLGGGRGKGIICAWAHSIGIGIYALVTLLG
CHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHH
LAVLLKQAPMVFNGIAIIGALYLAYMGIQALRSKGGMSDKLAAGKPTDAFSAARDGLAIS
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHCCCEEE
LFNPKIMLFFLALFSQFVMVADSLTGKALIVLTPLVVDGLWYTLIALVLSHASVLPKLRA
EECHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KAALIDKLSGVVLILLAVRVVVTL
HHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA