Click here to switch to the map view.

The map label for this gene is hlyB [H]

Identifier: 167625163

GI number: 167625163

Start: 3966080

End: 3967942

Strand: Reverse

Name: hlyB [H]

Synonym: Shal_3251

Alternate gene names: 167625163

Gene position: 3967942-3966080 (Counterclockwise)

Preceding gene: 167625168

Following gene: 167625162

Centisome position: 75.91

GC content: 47.61

Gene sequence:

>1863_bases
ATGCTAATACGTTACAAGTTACTGTTAAGTGCAGGCGTGTCGATCACGGCGTTAGCCGCCATGTTTGGTCTTCAAGTTTA
TTTTAGTCAAGTGCAAACGGAATTAGCACAAGCATCGCAAGATATCTCGGGGCTTAAGAATGAGATATTAATGCTACGTA
AAGATGAAAAGGACTTTCTGGCAAGAAAGGAGCTTAAGTATGTTGAGCAGCATATGTCCGACAATCGAGAGGCTCAGGAA
ACGGTAGTTAAGTTGACGGGAGTATTCGATAAATACTCTATTCCAACAGCGAGTTTAAGCCAGTTTAGTCAAGAGCTCGG
CCGTTATGAGTCCACATTCAGTAATGTGGTTAGCCTAAACAAGCAGATAGGTCTCACGCCGAAAACTGGTTTATATGGCA
CCTTGCGAAGCGCAGTGCATCAAGTCGAAAGCTTGGTTGAGCAATATGATGAACCACAATTGATGGTGCAGATGCTGCAA
CTTAGGCGCGCAGAGAAAGATTTTATGCTCAGGCGCAGTGAACGCTATGTGGCAAAGTTTGATAATAACCTCGAAGCATT
TATCAATACTGCGAATGTGTCGCAGCTGGACGGACAAGCCAAGCAGCAGGTGCTGAATTATATTCAACAATATAATGCTG
ACTTTAAAGCTCTAGTAGATAAAGAGAAACAACTCGGCCTCACGATTTCTGAAGGCGAGCGGGGCCAATTGCGTCAAGCC
GTTGCTAATACCGATAGTGCGCTTAATCAGCTTGAGTCTTTAGCCCTAGATGCGATTAGCGATAAAGAGAGTTCGGCATT
TATTTTTGGCCTTGCTATTGCGATCTTAATTGCTCTCGTTTTAGCGATTACAACCTTGATGATTATTCGTAGCATCATCG
ATCCCGTTAAACGTATTACCGATGTGATCACCCATATTGAGGAAAACAAAGATCTTTCGATGCGTTGTGATGCCAGCAGT
GACGATGAGCTTGGTCAAATTGCTAGACACTTCAACAGCATGGTTGAAAGTTTCCAGCAGCTTATCCATCAGGTGACTCA
GTCGGTTGAAACTATGAACCAATCTTGCCAAGCGCTTTCAGGTAATGTGGCGCGCGCCTCCCAAGGCGCTGAGAACCAGC
TAAATGAAACCGATATGGTGGCAACGGCGATCACCGAGATGGGAGCAACCATCGATGAGATCGCCAAGAACACTGAGCTT
GCGGCAAACAAAGCCAGTATGACCCACGACAATGCCCAAACTGGGCAGGTGGGTGTGCAGCAGACGATTGAGAAAATTGA
GTTGCTGGCGCAGCAGATCAATGAGTCTGCTGCTGTGGTGGCAGATCTTGAACAAGACAGTGAAACCATTGGTCGTGTGC
TCGAGGTTATTCGCGGCATTGCCGAGCAAACCAACTTACTGGCATTAAATGCCGCTATCGAAGCTGCTCGAGCCGGGGAA
CAGGGGCGAGGTTTCGCCGTTGTTGCCGATGAGGTGCGTAGTCTTGCGATGCGTACACAAGAGTCGACTGAGGAGATCGC
CGCGATTATTCAGACCTTACAGTCTCGAACTCATTCGATCGTTGAGATGATGCAATCGAGTCGTGAGCAGGGCAATGAGA
GTGCCGAGCAAGCGGCTTCAGCTGGCACCTTATTGCAGCAAATCAATAGCGACGTGACTAATATCATGGATATGAGCACG
CAAATTGCGGCGGCGATTGAAGAGCAGAGTATGGTAGCCGCAGAGGTTAATCAAAATGTGGTGGTGATCCGCGATATCGC
TCAGGAGACTGCAGAGGTAGCGACACAGAACTCCAGCGCGACTGAAGAGGTGCGTGAGCGTGCCGAGTATCTACAAGATG
CGGTGAGTAAGTTTAAGGTCTAG

Upstream 100 bases:

>100_bases
ATCTACTATATAATCGGCCGATAAGTTAAATGATAGCCTTGGTTAAACGTAGATTAGCGTTAGCTAAGGGAGGCAAGTTA
ATAATAAATAGAGATGTAAA

Downstream 100 bases:

>100_bases
CGATTTAGAGACGGTCTAGCGAAACCTTAGAGTGTCTAGTCCTAAAATAGGTTGACGGTTTTTATTAAGCCTCGAGTTAT
CTCGAGGCTTTTTTATGCAG

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 620; Mature: 620

Protein sequence:

>620_residues
MLIRYKLLLSAGVSITALAAMFGLQVYFSQVQTELAQASQDISGLKNEILMLRKDEKDFLARKELKYVEQHMSDNREAQE
TVVKLTGVFDKYSIPTASLSQFSQELGRYESTFSNVVSLNKQIGLTPKTGLYGTLRSAVHQVESLVEQYDEPQLMVQMLQ
LRRAEKDFMLRRSERYVAKFDNNLEAFINTANVSQLDGQAKQQVLNYIQQYNADFKALVDKEKQLGLTISEGERGQLRQA
VANTDSALNQLESLALDAISDKESSAFIFGLAIAILIALVLAITTLMIIRSIIDPVKRITDVITHIEENKDLSMRCDASS
DDELGQIARHFNSMVESFQQLIHQVTQSVETMNQSCQALSGNVARASQGAENQLNETDMVATAITEMGATIDEIAKNTEL
AANKASMTHDNAQTGQVGVQQTIEKIELLAQQINESAAVVADLEQDSETIGRVLEVIRGIAEQTNLLALNAAIEAARAGE
QGRGFAVVADEVRSLAMRTQESTEEIAAIIQTLQSRTHSIVEMMQSSREQGNESAEQAASAGTLLQQINSDVTNIMDMST
QIAAAIEEQSMVAAEVNQNVVVIRDIAQETAEVATQNSSATEEVRERAEYLQDAVSKFKV

Sequences:

>Translated_620_residues
MLIRYKLLLSAGVSITALAAMFGLQVYFSQVQTELAQASQDISGLKNEILMLRKDEKDFLARKELKYVEQHMSDNREAQE
TVVKLTGVFDKYSIPTASLSQFSQELGRYESTFSNVVSLNKQIGLTPKTGLYGTLRSAVHQVESLVEQYDEPQLMVQMLQ
LRRAEKDFMLRRSERYVAKFDNNLEAFINTANVSQLDGQAKQQVLNYIQQYNADFKALVDKEKQLGLTISEGERGQLRQA
VANTDSALNQLESLALDAISDKESSAFIFGLAIAILIALVLAITTLMIIRSIIDPVKRITDVITHIEENKDLSMRCDASS
DDELGQIARHFNSMVESFQQLIHQVTQSVETMNQSCQALSGNVARASQGAENQLNETDMVATAITEMGATIDEIAKNTEL
AANKASMTHDNAQTGQVGVQQTIEKIELLAQQINESAAVVADLEQDSETIGRVLEVIRGIAEQTNLLALNAAIEAARAGE
QGRGFAVVADEVRSLAMRTQESTEEIAAIIQTLQSRTHSIVEMMQSSREQGNESAEQAASAGTLLQQINSDVTNIMDMST
QIAAAIEEQSMVAAEVNQNVVVIRDIAQETAEVATQNSSATEEVRERAEYLQDAVSKFKV
>Mature_620_residues
MLIRYKLLLSAGVSITALAAMFGLQVYFSQVQTELAQASQDISGLKNEILMLRKDEKDFLARKELKYVEQHMSDNREAQE
TVVKLTGVFDKYSIPTASLSQFSQELGRYESTFSNVVSLNKQIGLTPKTGLYGTLRSAVHQVESLVEQYDEPQLMVQMLQ
LRRAEKDFMLRRSERYVAKFDNNLEAFINTANVSQLDGQAKQQVLNYIQQYNADFKALVDKEKQLGLTISEGERGQLRQA
VANTDSALNQLESLALDAISDKESSAFIFGLAIAILIALVLAITTLMIIRSIIDPVKRITDVITHIEENKDLSMRCDASS
DDELGQIARHFNSMVESFQQLIHQVTQSVETMNQSCQALSGNVARASQGAENQLNETDMVATAITEMGATIDEIAKNTEL
AANKASMTHDNAQTGQVGVQQTIEKIELLAQQINESAAVVADLEQDSETIGRVLEVIRGIAEQTNLLALNAAIEAARAGE
QGRGFAVVADEVRSLAMRTQESTEEIAAIIQTLQSRTHSIVEMMQSSREQGNESAEQAASAGTLLQQINSDVTNIMDMST
QIAAAIEEQSMVAAEVNQNVVVIRDIAQETAEVATQNSSATEEVRERAEYLQDAVSKFKV

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=423, Percent_Identity=29.3144208037825, Blast_Score=139, Evalue=6e-34,
Organism=Escherichia coli, GI2367378, Length=319, Percent_Identity=29.7805642633229, Blast_Score=117, Evalue=3e-27,
Organism=Escherichia coli, GI1788195, Length=335, Percent_Identity=30.1492537313433, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1788194, Length=361, Percent_Identity=29.3628808864266, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1789453, Length=343, Percent_Identity=26.530612244898, Blast_Score=101, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 68262; Mature: 68262

Theoretical pI: Translated: 4.40; Mature: 4.40

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIRYKLLLSAGVSITALAAMFGLQVYFSQVQTELAQASQDISGLKNEILMLRKDEKDFL
CEEEHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
ARKELKYVEQHMSDNREAQETVVKLTGVFDKYSIPTASLSQFSQELGRYESTFSNVVSLN
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
KQIGLTPKTGLYGTLRSAVHQVESLVEQYDEPQLMVQMLQLRRAEKDFMLRRSERYVAKF
HHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DNNLEAFINTANVSQLDGQAKQQVLNYIQQYNADFKALVDKEKQLGLTISEGERGQLRQA
CCCHHHHHCCCCHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCEECCCCHHHHHHH
VANTDSALNQLESLALDAISDKESSAFIFGLAIAILIALVLAITTLMIIRSIIDPVKRIT
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DVITHIEENKDLSMRCDASSDDELGQIARHFNSMVESFQQLIHQVTQSVETMNQSCQALS
HHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GNVARASQGAENQLNETDMVATAITEMGATIDEIAKNTELAANKASMTHDNAQTGQVGVQ
CCHHHHCCCCHHCCCHHHHHHHHHHHHCCHHHHHHCCHHHHHCHHHCCCCCCCCCHHHHH
QTIEKIELLAQQINESAAVVADLEQDSETIGRVLEVIRGIAEQTNLLALNAAIEAARAGE
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
QGRGFAVVADEVRSLAMRTQESTEEIAAIIQTLQSRTHSIVEMMQSSREQGNESAEQAAS
CCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
AGTLLQQINSDVTNIMDMSTQIAAAIEEQSMVAAEVNQNVVVIRDIAQETAEVATQNSSA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHCCCCH
TEEVRERAEYLQDAVSKFKV
HHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLIRYKLLLSAGVSITALAAMFGLQVYFSQVQTELAQASQDISGLKNEILMLRKDEKDFL
CEEEHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
ARKELKYVEQHMSDNREAQETVVKLTGVFDKYSIPTASLSQFSQELGRYESTFSNVVSLN
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
KQIGLTPKTGLYGTLRSAVHQVESLVEQYDEPQLMVQMLQLRRAEKDFMLRRSERYVAKF
HHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DNNLEAFINTANVSQLDGQAKQQVLNYIQQYNADFKALVDKEKQLGLTISEGERGQLRQA
CCCHHHHHCCCCHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCEECCCCHHHHHHH
VANTDSALNQLESLALDAISDKESSAFIFGLAIAILIALVLAITTLMIIRSIIDPVKRIT
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DVITHIEENKDLSMRCDASSDDELGQIARHFNSMVESFQQLIHQVTQSVETMNQSCQALS
HHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GNVARASQGAENQLNETDMVATAITEMGATIDEIAKNTELAANKASMTHDNAQTGQVGVQ
CCHHHHCCCCHHCCCHHHHHHHHHHHHCCHHHHHHCCHHHHHCHHHCCCCCCCCCHHHHH
QTIEKIELLAQQINESAAVVADLEQDSETIGRVLEVIRGIAEQTNLLALNAAIEAARAGE
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
QGRGFAVVADEVRSLAMRTQESTEEIAAIIQTLQSRTHSIVEMMQSSREQGNESAEQAAS
CCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
AGTLLQQINSDVTNIMDMSTQIAAAIEEQSMVAAEVNQNVVVIRDIAQETAEVATQNSSA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHCCCCH
TEEVRERAEYLQDAVSKFKV
HHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]