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The map label for this gene is apbE [H]

Identifier: 167625093

GI number: 167625093

Start: 3885516

End: 3886532

Strand: Reverse

Name: apbE [H]

Synonym: Shal_3181

Alternate gene names: 167625093

Gene position: 3886532-3885516 (Counterclockwise)

Preceding gene: 167625094

Following gene: 167625092

Centisome position: 74.36

GC content: 42.48

Gene sequence:

>1017_bases
ATGCAAAAGATCTTGGTGAAATGGTTAGCAGTTATTGGGCTAGCCTTTTTTATTTCAGCTTGCTCAAAACCGCCCGAAAT
TATCTCTTTGTCTGGCAACACGATGGGGACGACTTATCATATTAAGCTTGTACCTAACGACGAGATGCCTGATGCACAGT
CATTGCAAACAGAGATCGATTTAGCCCTTGAAAAGGTGAACGATCAGATGTCGACATATCGTCCTGAATCAGAGTTGTCT
CAGTTTAATCAGATGATCCATAATGAGAATATGGAAGTATCGACCGATACGGCTAAAGTGATTGCCGAAGGCTTAACGCT
TTATAAAAAAACCGATGGTGCCTTAGATATTACCTTAGGCCCTTTAGTTAACTTATGGGGCTTTGGCCCAGATAAAAGGC
CGACGCAAATTCCATCTCAGCAAGAGATTGATTTGGCTATGGAGCGCATGGGTATTGAGGAGATTGCTGTTGATGGTAAT
AAAATCAGCAAGCAAAATCCTGATATCTATGTCGATCTATCTTCGATTGCAAAAGGCTTCGGTGTTGATAAAATAGCCGC
CTTATTGGATAAGTATAACCTGACCGGATATTTAGTTGAGATTGGCGGAGAAGTCAGCCTTCATGGCACTAAAGCCGATG
GTTCATTATGGCGTATTGCGATAGAGCAGCCAGATGATGACGGAACTGAGATCCAGCAGATAATTTCACTCAAAAATATG
GCGATGGCAACATCGGGTGATTATCGTAATTATTACGAGGAAGACGGCAAGCGTTTTTCACACCTGATCGATCCTCGTAC
AGGCTACCCAATAAACCATAGATTAGCGTCTGTGACGGTACTGCATGAAGAGTGTATGATTGCAGATGGTTACGCGACTG
CTATGATGGTGTTAGGTACTCAAGCATCACTAGAGCTGGCTAAACGCGAGCATCTAGCGATAATGCTTATTGAAAAGCAA
GATGATGGCTTTAAAGTTTTCTATAGTGAAGCTTTCAAACCTCTCGTTACTCAGTAG

Upstream 100 bases:

>100_bases
AGTGTCGTCATCGAGTGTGGAAAGTGGAGGTTGATAAGCTCATGCCACTTTCCTTTCTAAGCCCTCGATAGTCTTAAGTG
GAATATAAGGATTTAGGTCA

Downstream 100 bases:

>100_bases
TTGGAGTCGAATATGAGCACATTTATTGCGGCTTTTGTCGTGTTATTAGGTTTCTTTTTCTTAATGTCGATAGGCTATTT
AGTCAAACGAAAAGCTGTAG

Product: ApbE family lipoprotein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MQKILVKWLAVIGLAFFISACSKPPEIISLSGNTMGTTYHIKLVPNDEMPDAQSLQTEIDLALEKVNDQMSTYRPESELS
QFNQMIHNENMEVSTDTAKVIAEGLTLYKKTDGALDITLGPLVNLWGFGPDKRPTQIPSQQEIDLAMERMGIEEIAVDGN
KISKQNPDIYVDLSSIAKGFGVDKIAALLDKYNLTGYLVEIGGEVSLHGTKADGSLWRIAIEQPDDDGTEIQQIISLKNM
AMATSGDYRNYYEEDGKRFSHLIDPRTGYPINHRLASVTVLHEECMIADGYATAMMVLGTQASLELAKREHLAIMLIEKQ
DDGFKVFYSEAFKPLVTQ

Sequences:

>Translated_338_residues
MQKILVKWLAVIGLAFFISACSKPPEIISLSGNTMGTTYHIKLVPNDEMPDAQSLQTEIDLALEKVNDQMSTYRPESELS
QFNQMIHNENMEVSTDTAKVIAEGLTLYKKTDGALDITLGPLVNLWGFGPDKRPTQIPSQQEIDLAMERMGIEEIAVDGN
KISKQNPDIYVDLSSIAKGFGVDKIAALLDKYNLTGYLVEIGGEVSLHGTKADGSLWRIAIEQPDDDGTEIQQIISLKNM
AMATSGDYRNYYEEDGKRFSHLIDPRTGYPINHRLASVTVLHEECMIADGYATAMMVLGTQASLELAKREHLAIMLIEKQ
DDGFKVFYSEAFKPLVTQ
>Mature_338_residues
MQKILVKWLAVIGLAFFISACSKPPEIISLSGNTMGTTYHIKLVPNDEMPDAQSLQTEIDLALEKVNDQMSTYRPESELS
QFNQMIHNENMEVSTDTAKVIAEGLTLYKKTDGALDITLGPLVNLWGFGPDKRPTQIPSQQEIDLAMERMGIEEIAVDGN
KISKQNPDIYVDLSSIAKGFGVDKIAALLDKYNLTGYLVEIGGEVSLHGTKADGSLWRIAIEQPDDDGTEIQQIISLKNM
AMATSGDYRNYYEEDGKRFSHLIDPRTGYPINHRLASVTVLHEECMIADGYATAMMVLGTQASLELAKREHLAIMLIEKQ
DDGFKVFYSEAFKPLVTQ

Specific function: Involved in the conversion of aminoimidazole ribotide (AIR), a purine intermediate, to the 4-amino-5-hydroxymethyl-2- methyl pyrimidine (HMP) moiety of thiamine [H]

COG id: COG1477

COG function: function code H; Membrane-associated lipoprotein involved in thiamine biosynthesis

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ApbE family [H]

Homologues:

Organism=Escherichia coli, GI1788543, Length=340, Percent_Identity=38.2352941176471, Blast_Score=262, Evalue=2e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003374 [H]

Pfam domain/function: PF02424 ApbE [H]

EC number: NA

Molecular weight: Translated: 37541; Mature: 37541

Theoretical pI: Translated: 4.50; Mature: 4.50

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKILVKWLAVIGLAFFISACSKPPEIISLSGNTMGTTYHIKLVPNDEMPDAQSLQTEID
CHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCEEEEEEECCCCCCCCHHHHHHHHH
LALEKVNDQMSTYRPESELSQFNQMIHNENMEVSTDTAKVIAEGLTLYKKTDGALDITLG
HHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEECHHHHHHHHHHHEEEECCCEEEEEHH
PLVNLWGFGPDKRPTQIPSQQEIDLAMERMGIEEIAVDGNKISKQNPDIYVDLSSIAKGF
HHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCHHHEEECCCCCCCCCCCEEEEHHHHHCCC
GVDKIAALLDKYNLTGYLVEIGGEVSLHGTKADGSLWRIAIEQPDDDGTEIQQIISLKNM
CHHHHHHHHHHCCCCEEEEEECCEEEEEEEECCCCEEEEEEECCCCCHHHHHHHHHHHHH
AMATSGDYRNYYEEDGKRFSHLIDPRTGYPINHRLASVTVLHEECMIADGYATAMMVLGT
HEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHEEEEEEHHHHEEECCHHHHHHHHCC
QASLELAKREHLAIMLIEKQDDGFKVFYSEAFKPLVTQ
HHHHHHHHCCCEEEEEEEECCCCEEEEEHHHCHHHCCC
>Mature Secondary Structure
MQKILVKWLAVIGLAFFISACSKPPEIISLSGNTMGTTYHIKLVPNDEMPDAQSLQTEID
CHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCEEEEEEECCCCCCCCHHHHHHHHH
LALEKVNDQMSTYRPESELSQFNQMIHNENMEVSTDTAKVIAEGLTLYKKTDGALDITLG
HHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEECHHHHHHHHHHHEEEECCCEEEEEHH
PLVNLWGFGPDKRPTQIPSQQEIDLAMERMGIEEIAVDGNKISKQNPDIYVDLSSIAKGF
HHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCHHHEEECCCCCCCCCCCEEEEHHHHHCCC
GVDKIAALLDKYNLTGYLVEIGGEVSLHGTKADGSLWRIAIEQPDDDGTEIQQIISLKNM
CHHHHHHHHHHCCCCEEEEEECCEEEEEEEECCCCEEEEEEECCCCCHHHHHHHHHHHHH
AMATSGDYRNYYEEDGKRFSHLIDPRTGYPINHRLASVTVLHEECMIADGYATAMMVLGT
HEECCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHEEEEEEHHHHEEECCHHHHHHHHCC
QASLELAKREHLAIMLIEKQDDGFKVFYSEAFKPLVTQ
HHHHHHHHCCCEEEEEEEECCCCEEEEEHHHCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]