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The map label for this gene is yaeL [C]

Identifier: 167624888

GI number: 167624888

Start: 3618300

End: 3619670

Strand: Reverse

Name: yaeL [C]

Synonym: Shal_2974

Alternate gene names: 167624888

Gene position: 3619670-3618300 (Counterclockwise)

Preceding gene: 167624889

Following gene: 167624887

Centisome position: 69.25

GC content: 45.73

Gene sequence:

>1371_bases
ATGATCGATTTTTTATGGAACCTAGGTTCCTTTATTGTTGCCTTAGGGATCTTAATTGCAGCCCATGAATACGGGCACTT
TTGGGTTGCTCGTCGCTGTGGTGTTAAAGTTGAGCGCTTTTCCATCGGATTTGGCAAAGCCATTTGGCGCAAGACTGGCA
AAGACGGTACCGAGTATGTCATCGCGATGATCCCGCTGGGTGGTTATGTCAAAATGCTCGACGAGCGTGTTGATGACGTG
CCTGAAGAGTTAAAAGATCAAGCCTTTAACCGTAAATCAGTTTGGCAGCGTATCGCAATTGTCAGCGCAGGCCCGATTGC
GAACTTCATCTTTGCGATTATCGCTCTCTACGCAATGTATCTTATTGGTGTTCCAGCCATTAAACCCGTTATTGACTCTA
CTATTGCAGGTACTCCTGCGGCACAAATTGTCGTCAAAGAGCCAATGCAGATCATGTCAGTTGGTAACCAAAAGGTCAGA
GATTGGGAGGAGGTTAACCTTGCCCTTGCCAGTCATATTGGTGACAGCAAGGTCGATTTAACTGTAGCACCACTGTCTCG
CCTAGAAGGTACCTCTGGTGATGAGCAAACGTATTCGTTAAATACTCAGAATTGGAACGTTAATCTTGAGAAAGAGCTAC
CGATTACTGCGATTGGCCTTGGCATGTATCGCCCTGCGATATTACCGACGCTGGCATTAGTCAGTGATGACGGCGCAGCG
GGTCTTGCCGGTATCAAGGTGGGTGACACCTTAGTTGCGATTGATGGTGAAAAGTACCAAGATTGGCCGCGTTTCGTCGA
AATTATTCAGGGTTCTGCTAATAAGACTGTCACTATTACCATACGTCGTGATGGAGAGCAGTTGGCGATTAAGGTCACAC
CCAAGTCTCGAGAAAATGCCGAAGGTAAACTTGAAGGCGTGATTGGCGTGGCGCCAACTTCTGAGCCATGGCCTGAAAAC
ATGAAGATACAATTGGAATACGGATTTTTAGATTCTTTTCCGGTTGCAGTCGATAAAACATGGCAACTTGTCTCTGTCAG
CATTAAGATGATTGGCAAGTTACTTACCGGTGACGTTTCAGTTAAAAATTTGAGTGGCCCAATTTCTATTGCACAAGGTG
CAGGAAATAGCGCTGACGTCGGACTGGTATATTTTTTAGGTTTTCTTGCATTGATTAGCGTGAACTTAGGCATTATTAAT
TTATTGCCTTTGCCAGTGTTAGATGGGGGACACCTTTTGTATTACTTCGTTGAGGTAATTACAGGCAGGCCTGTACCGGA
GAAGGTACAGGAAATTGGATTCAGAATTGGGGCAGCTATGCTGCTGCTGTTGATGAGCGTTGCGCTTTTCAATGACTTTT
CCCGACTCTGA

Upstream 100 bases:

>100_bases
ATCCATTAAACAGTATTGATGATATCTTGGCGTTAGATTTTCAAAGCCGTCAATCTACATTAGACGCCATCACTAAGCTG
AATTAGTTCAGAGGAAAGGA

Downstream 100 bases:

>100_bases
GCAAGGACAGACAAATAATTAGAAGTGCTCTATGAGATTGAATAAACTTTTTGCCTCGATGTTATTCGTCGGAGCGTCTT
TTTCAGGGAACGGTTGGGCC

Product: putative membrane-associated zinc metalloprotease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 456; Mature: 456

Protein sequence:

>456_residues
MIDFLWNLGSFIVALGILIAAHEYGHFWVARRCGVKVERFSIGFGKAIWRKTGKDGTEYVIAMIPLGGYVKMLDERVDDV
PEELKDQAFNRKSVWQRIAIVSAGPIANFIFAIIALYAMYLIGVPAIKPVIDSTIAGTPAAQIVVKEPMQIMSVGNQKVR
DWEEVNLALASHIGDSKVDLTVAPLSRLEGTSGDEQTYSLNTQNWNVNLEKELPITAIGLGMYRPAILPTLALVSDDGAA
GLAGIKVGDTLVAIDGEKYQDWPRFVEIIQGSANKTVTITIRRDGEQLAIKVTPKSRENAEGKLEGVIGVAPTSEPWPEN
MKIQLEYGFLDSFPVAVDKTWQLVSVSIKMIGKLLTGDVSVKNLSGPISIAQGAGNSADVGLVYFLGFLALISVNLGIIN
LLPLPVLDGGHLLYYFVEVITGRPVPEKVQEIGFRIGAAMLLLLMSVALFNDFSRL

Sequences:

>Translated_456_residues
MIDFLWNLGSFIVALGILIAAHEYGHFWVARRCGVKVERFSIGFGKAIWRKTGKDGTEYVIAMIPLGGYVKMLDERVDDV
PEELKDQAFNRKSVWQRIAIVSAGPIANFIFAIIALYAMYLIGVPAIKPVIDSTIAGTPAAQIVVKEPMQIMSVGNQKVR
DWEEVNLALASHIGDSKVDLTVAPLSRLEGTSGDEQTYSLNTQNWNVNLEKELPITAIGLGMYRPAILPTLALVSDDGAA
GLAGIKVGDTLVAIDGEKYQDWPRFVEIIQGSANKTVTITIRRDGEQLAIKVTPKSRENAEGKLEGVIGVAPTSEPWPEN
MKIQLEYGFLDSFPVAVDKTWQLVSVSIKMIGKLLTGDVSVKNLSGPISIAQGAGNSADVGLVYFLGFLALISVNLGIIN
LLPLPVLDGGHLLYYFVEVITGRPVPEKVQEIGFRIGAAMLLLLMSVALFNDFSRL
>Mature_456_residues
MIDFLWNLGSFIVALGILIAAHEYGHFWVARRCGVKVERFSIGFGKAIWRKTGKDGTEYVIAMIPLGGYVKMLDERVDDV
PEELKDQAFNRKSVWQRIAIVSAGPIANFIFAIIALYAMYLIGVPAIKPVIDSTIAGTPAAQIVVKEPMQIMSVGNQKVR
DWEEVNLALASHIGDSKVDLTVAPLSRLEGTSGDEQTYSLNTQNWNVNLEKELPITAIGLGMYRPAILPTLALVSDDGAA
GLAGIKVGDTLVAIDGEKYQDWPRFVEIIQGSANKTVTITIRRDGEQLAIKVTPKSRENAEGKLEGVIGVAPTSEPWPEN
MKIQLEYGFLDSFPVAVDKTWQLVSVSIKMIGKLLTGDVSVKNLSGPISIAQGAGNSADVGLVYFLGFLALISVNLGIIN
LLPLPVLDGGHLLYYFVEVITGRPVPEKVQEIGFRIGAAMLLLLMSVALFNDFSRL

Specific function: Unknown

COG id: COG0750

COG function: function code M; Predicted membrane-associated Zn-dependent proteases 1

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1786373, Length=456, Percent_Identity=50.4385964912281, Blast_Score=449, Evalue=1e-127,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR004387
- InterPro:   IPR008915 [H]

Pfam domain/function: PF00595 PDZ; PF02163 Peptidase_M50 [H]

EC number: NA

Molecular weight: Translated: 49609; Mature: 49609

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: PS50106 PDZ ; PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDFLWNLGSFIVALGILIAAHEYGHFWVARRCGVKVERFSIGFGKAIWRKTGKDGTEYV
CCCHHHHHHHHHHHHHHHHHHHHCCCEEEHHHCCCEEEEEECCHHHHHHHHCCCCCCEEE
IAMIPLGGYVKMLDERVDDVPEELKDQAFNRKSVWQRIAIVSAGPIANFIFAIIALYAMY
EEEECCCHHHHHHHHHHHHCHHHHHHHHCCHHHHHHHHHHEECCHHHHHHHHHHHHHHHH
LIGVPAIKPVIDSTIAGTPAAQIVVKEPMQIMSVGNQKVRDWEEVNLALASHIGDSKVDL
HHCCCHHHHHHHHHCCCCCHHHHEECCCHHHHHCCCHHCCCHHHHHHHHHHHCCCCCEEE
TVAPLSRLEGTSGDEQTYSLNTQNWNVNLEKELPITAIGLGMYRPAILPTLALVSDDGAA
EEECHHHCCCCCCCCCEEEEECCCEEEEECCCCCEEEEEHHHHCHHHHHHEEEECCCCCC
GLAGIKVGDTLVAIDGEKYQDWPRFVEIIQGSANKTVTITIRRDGEQLAIKVTPKSRENA
CEEEEEECCEEEEECCCCCHHHHHHHHHHCCCCCCEEEEEEEECCCEEEEEECCCCCCCC
EGKLEGVIGVAPTSEPWPENMKIQLEYGFLDSFPVAVDKTWQLVSVSIKMIGKLLTGDVS
CCCEEEEEEECCCCCCCCCCCEEEEEECCCCCCCCEECCCHHHHHHHHHHHHHHHCCCCE
VKNLSGPISIAQGAGNSADVGLVYFLGFLALISVNLGIINLLPLPVLDGGHLLYYFVEVI
EECCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCEECCCHHHHHHHHHH
TGRPVPEKVQEIGFRIGAAMLLLLMSVALFNDFSRL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIDFLWNLGSFIVALGILIAAHEYGHFWVARRCGVKVERFSIGFGKAIWRKTGKDGTEYV
CCCHHHHHHHHHHHHHHHHHHHHCCCEEEHHHCCCEEEEEECCHHHHHHHHCCCCCCEEE
IAMIPLGGYVKMLDERVDDVPEELKDQAFNRKSVWQRIAIVSAGPIANFIFAIIALYAMY
EEEECCCHHHHHHHHHHHHCHHHHHHHHCCHHHHHHHHHHEECCHHHHHHHHHHHHHHHH
LIGVPAIKPVIDSTIAGTPAAQIVVKEPMQIMSVGNQKVRDWEEVNLALASHIGDSKVDL
HHCCCHHHHHHHHHCCCCCHHHHEECCCHHHHHCCCHHCCCHHHHHHHHHHHCCCCCEEE
TVAPLSRLEGTSGDEQTYSLNTQNWNVNLEKELPITAIGLGMYRPAILPTLALVSDDGAA
EEECHHHCCCCCCCCCEEEEECCCEEEEECCCCCEEEEEHHHHCHHHHHHEEEECCCCCC
GLAGIKVGDTLVAIDGEKYQDWPRFVEIIQGSANKTVTITIRRDGEQLAIKVTPKSRENA
CEEEEEECCEEEEECCCCCHHHHHHHHHHCCCCCCEEEEEEEECCCEEEEEECCCCCCCC
EGKLEGVIGVAPTSEPWPENMKIQLEYGFLDSFPVAVDKTWQLVSVSIKMIGKLLTGDVS
CCCEEEEEEECCCCCCCCCCCEEEEEECCCCCCCCEECCCHHHHHHHHHHHHHHHCCCCE
VKNLSGPISIAQGAGNSADVGLVYFLGFLALISVNLGIINLLPLPVLDGGHLLYYFVEVI
EECCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCEECCCHHHHHHHHHH
TGRPVPEKVQEIGFRIGAAMLLLLMSVALFNDFSRL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]