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The map label for this gene is mrdB [H]

Identifier: 167624772

GI number: 167624772

Start: 3473000

End: 3474091

Strand: Reverse

Name: mrdB [H]

Synonym: Shal_2856

Alternate gene names: 167624772

Gene position: 3474091-3473000 (Counterclockwise)

Preceding gene: 167624773

Following gene: 167624771

Centisome position: 66.47

GC content: 43.13

Gene sequence:

>1092_bases
ATGAAGATAGATATGTTTAAATACACTCCTCGAATTGACTTCCCGTTATTACTTGCTATTTCGTTGTTGATTCTGCTTGG
CTCACTCACGGTATGGAGCGCCAGTGGTTTCAGTGAGTCTATGCTAGAGCGGCACCTTATTAGAGCTTTTATTGCGATCG
GCTGTATTGTTGTTATGTCAGTCATCCCACCAAGGCGGTATCAGCGAGCAACCCCTTATCTATATGCTGTGGCGGTAATT
CTGCTGCTCGGAGTCATTTTTGCTGGTGATAGTACTAACGGTTCTCAACGTTGGTTGGTTATTGGGCCGATTCGATTCCA
GCCCTCTGAGTTAGTCAAAGTCGCTATCCCCTTGATGGTTGCATGGATTTTAGTTGCCGAAGGTGGACGCCCTGATATTA
AAAAAATCTTCATCTGTCTACTCGTCACTTCGGTTCCAGCGGGGTTGATATTTATTCAGCCCGATCTAGATGGGGCGATA
TTCACCGTTATCTACGCGCTATTTGTTTTGTATTTTGCTGGAATGAGCTGGAAAATTATTGGTTCATTTCTCGCTGGAGT
CACAATTACTATCCCTATGTTGTGGTTTTTTGTAATGGAAGCCTATCAAAAAAAGCGTGTGACTCAATTTCTGGATCCTG
AATCCGATCCCCTTGGTGCGGGTTACCAAATTATTCAATCATTGATTGCAATTGGTTCTGGGGGAATGCACGGAAAAGGT
TGGACAAATGCGACGCAGGGTCAGCTTGGATTCATTCCGGAAAGTCATACTGACTTTATTTTCTCAACCTATGCAGAGCA
GTGGGGCTTTATCGGATGCTTACTCTTGGTAGGACTCTATTTGTTTATTACAGGACGAGTCATTTGGTTAGCTTATCAAT
GTAATTCGTCATTCAACCGTTTAGTCAGCGCCACTTTTGCGCTCAGTTTCTTCTTATATGCCTTTATTAATATGGGGATG
GTGAGTGGTTTACTGCCAGTAATGGGGAGCCCATTACCCTTCTTTAGTTATGGCGGTACAGCCATGATCACCCAAGGAAT
TTGTTTCGGCATTATTATGTCCCTTTGCCTACAAAAATCTTATAAACCATAA

Upstream 100 bases:

>100_bases
AACAAGTTTATTTTAAAAACTAAAAAACTGTTTATACTCTCCCGCATTATGATCACCAGTTTGCTTGTCTCTCTGTTTGA
TATCTCATGTTTTATGTTGA

Downstream 100 bases:

>100_bases
CAGTTGAGCATGGAAGCAGCATAGAGCTAGAAGTGACACTTCTAGCTCGCATTTATCCAAAATAGCACTTCATCGATCCA
AGCTTCCAAATTAGCGATGT

Product: rod shape-determining protein RodA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 363; Mature: 363

Protein sequence:

>363_residues
MKIDMFKYTPRIDFPLLLAISLLILLGSLTVWSASGFSESMLERHLIRAFIAIGCIVVMSVIPPRRYQRATPYLYAVAVI
LLLGVIFAGDSTNGSQRWLVIGPIRFQPSELVKVAIPLMVAWILVAEGGRPDIKKIFICLLVTSVPAGLIFIQPDLDGAI
FTVIYALFVLYFAGMSWKIIGSFLAGVTITIPMLWFFVMEAYQKKRVTQFLDPESDPLGAGYQIIQSLIAIGSGGMHGKG
WTNATQGQLGFIPESHTDFIFSTYAEQWGFIGCLLLVGLYLFITGRVIWLAYQCNSSFNRLVSATFALSFFLYAFINMGM
VSGLLPVMGSPLPFFSYGGTAMITQGICFGIIMSLCLQKSYKP

Sequences:

>Translated_363_residues
MKIDMFKYTPRIDFPLLLAISLLILLGSLTVWSASGFSESMLERHLIRAFIAIGCIVVMSVIPPRRYQRATPYLYAVAVI
LLLGVIFAGDSTNGSQRWLVIGPIRFQPSELVKVAIPLMVAWILVAEGGRPDIKKIFICLLVTSVPAGLIFIQPDLDGAI
FTVIYALFVLYFAGMSWKIIGSFLAGVTITIPMLWFFVMEAYQKKRVTQFLDPESDPLGAGYQIIQSLIAIGSGGMHGKG
WTNATQGQLGFIPESHTDFIFSTYAEQWGFIGCLLLVGLYLFITGRVIWLAYQCNSSFNRLVSATFALSFFLYAFINMGM
VSGLLPVMGSPLPFFSYGGTAMITQGICFGIIMSLCLQKSYKP
>Mature_363_residues
MKIDMFKYTPRIDFPLLLAISLLILLGSLTVWSASGFSESMLERHLIRAFIAIGCIVVMSVIPPRRYQRATPYLYAVAVI
LLLGVIFAGDSTNGSQRWLVIGPIRFQPSELVKVAIPLMVAWILVAEGGRPDIKKIFICLLVTSVPAGLIFIQPDLDGAI
FTVIYALFVLYFAGMSWKIIGSFLAGVTITIPMLWFFVMEAYQKKRVTQFLDPESDPLGAGYQIIQSLIAIGSGGMHGKG
WTNATQGQLGFIPESHTDFIFSTYAEQWGFIGCLLLVGLYLFITGRVIWLAYQCNSSFNRLVSATFALSFFLYAFINMGM
VSGLLPVMGSPLPFFSYGGTAMITQGICFGIIMSLCLQKSYKP

Specific function: This is one of the proteins responsible for the rod shape of the cell. It is required for the expression of the enzymatic activity of PBP2, which is thought to synthesize peptidoglycan in the step of initiation of cell elongation [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786853, Length=333, Percent_Identity=47.4474474474475, Blast_Score=301, Evalue=3e-83,
Organism=Escherichia coli, GI1786277, Length=305, Percent_Identity=32.1311475409836, Blast_Score=157, Evalue=1e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR011923 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 40085; Mature: 40085

Theoretical pI: Translated: 8.91; Mature: 8.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIDMFKYTPRIDFPLLLAISLLILLGSLTVWSASGFSESMLERHLIRAFIAIGCIVVMS
CCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
VIPPRRYQRATPYLYAVAVILLLGVIFAGDSTNGSQRWLVIGPIRFQPSELVKVAIPLMV
HCCCHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHH
AWILVAEGGRPDIKKIFICLLVTSVPAGLIFIQPDLDGAIFTVIYALFVLYFAGMSWKII
HHHHHHCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHCCCHHHHH
GSFLAGVTITIPMLWFFVMEAYQKKRVTQFLDPESDPLGAGYQIIQSLIAIGSGGMHGKG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCCCC
WTNATQGQLGFIPESHTDFIFSTYAEQWGFIGCLLLVGLYLFITGRVIWLAYQCNSSFNR
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHH
LVSATFALSFFLYAFINMGMVSGLLPVMGSPLPFFSYGGTAMITQGICFGIIMSLCLQKS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHC
YKP
CCC
>Mature Secondary Structure
MKIDMFKYTPRIDFPLLLAISLLILLGSLTVWSASGFSESMLERHLIRAFIAIGCIVVMS
CCCCCEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
VIPPRRYQRATPYLYAVAVILLLGVIFAGDSTNGSQRWLVIGPIRFQPSELVKVAIPLMV
HCCCHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHH
AWILVAEGGRPDIKKIFICLLVTSVPAGLIFIQPDLDGAIFTVIYALFVLYFAGMSWKII
HHHHHHCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHCCCHHHHH
GSFLAGVTITIPMLWFFVMEAYQKKRVTQFLDPESDPLGAGYQIIQSLIAIGSGGMHGKG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCCCC
WTNATQGQLGFIPESHTDFIFSTYAEQWGFIGCLLLVGLYLFITGRVIWLAYQCNSSFNR
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHH
LVSATFALSFFLYAFINMGMVSGLLPVMGSPLPFFSYGGTAMITQGICFGIIMSLCLQKS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHC
YKP
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]