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The map label for this gene is ppiD [H]

Identifier: 167624682

GI number: 167624682

Start: 3353174

End: 3355039

Strand: Reverse

Name: ppiD [H]

Synonym: Shal_2764

Alternate gene names: 167624682

Gene position: 3355039-3353174 (Counterclockwise)

Preceding gene: 167624683

Following gene: 167624674

Centisome position: 64.19

GC content: 44.16

Gene sequence:

>1866_bases
ATGTTAGAAAAGATTCGCGAAGGCTCACAAGGTGTCATTGCTAAAAGTATATTAGTCCTTGTGATACTTTCTTTTGCATT
TACCGGTGTAAGTAGTTATTTGGGTTCTTCAACTGAGGTTGCAGCTGCTACCGTAAATGGTGAAGAGATCAGCAACTCAG
CTTTAGAGCAAGCATATCAAAATGAACGTAGTCGTTTAGAGCAACAGTTAGGCGATATGTTTGCCACACTGTCAGCTGAT
GATAACTACATGCAAAGCGTTAAGCAAAGCGTTTTAGAGCGTTTAGTGGCTGAGACGTTATTAGACCAAAATGCGGCTGA
GTTAGGATTGCGCGTATCTGATGAGCAGATTAAAGCGGCAATTATGACAGAGCCTGCATTCCAAACTGACGGCCGTTTCG
ATAACGATCGTTACCAAGCTATTCTGCGTCAGTTAGGTTATCAGGCGAACTCTTTCCGCGACATGATGCGTACCGATATG
ACTCGCCGTCAGCTTGTTGCTACCTTAGTGGGTTCTGAATTTGTTTTACCTGGTGAAGCCAAGTATTTGGCCGATCTTCA
AGGTCAGACACGTGATATCGACTACAAGGTTATCGATGCGACTCCTTTCCTAGCTGACATCAGTGTTACCGATGAGCAGA
TCAAGACTTATTACGATTCAAATCTAGACCAATTTATTCGTCCAGAAGTCGTTAGTCTTGACTACATCGAGCTTGATGCA
AAAGATCTAGCTAAAGATGTAAAAGTAACCGATGCTGACGCACAAGCTTATTATGACGAGCATAAAGCTAACTACACACA
AGCTGAGAAGCGCTTAGCGGCGCATATCCTTGTTCAAGCTGGTGACGATGACGCAGCGGCTAAAGCGAAAGCCGAAGCTA
TCTATAAGCAACTTCAAGACGGTGCTGACTTCGCAGAACTTGCAAAGACAGAATCTGAAGATACTTTTAGCGGTGAGCAG
GGTGGTCAACTAGATTGGTTTGAAGCGGGTGTTATGGAGCCTGAGTTTGACACCGCACTGTTTGCACTTAATAAAGGTGA
CTATTCAAATGTTGTGAAAACAAACTTTGGTTATCACATTATTAAGTTGTTGGATATCCAAGCCGGTGCAGAGGCCCCAT
TTGCTGACGTTAAAGAAAAAATCATTGCTCAACTTCAAGAGAAGCAAGCGGTAGACAAATTCTACGAGTTACAGCAAGTG
TTAGCCGATACCAGCTACGAAGTGCCTGATACGCTAGTCGATGCGGCGAAAGATTTAGGTGTTGAGGTTAAGACAACTGT
TGAATTTGCACGTACTAATCCACCAGAACTATTTAGCAATCCTGACTTGCTAAAAGAAGCATTCTCTTCGAATGTGTTAC
TGGATGGTATGAATAGCGATGTGTTAGAAGTAGAGCCAAACCATGTGGTGGTTATTCGCGTGAATACCCATAAAGCTGCG
GGCACTATGGACTTAGCTGACGTTCGCAATGCAATCGCTAACCGTTTAAAGCAAGAGCAAGCTAATGAAGCAGCACGCAA
GCAAGCTCAAGAGCTGATGACTGCGGTTGAAGCCTCAGGCGTTACCTCAGACTTTATCGTTAAAGATAAGCTTGCACGTT
TTGAGCAAGACGTTGATGGCGCGATTGTAAATAAGGCGTTCTCTATGGCACAGCCAAGCGACAAGGCTTCTGTTGATACC
GTAGCGCTTGCAAATGGCTACGCAGTCGTAGTGTTGAAGCAAGTTAATGCTGCTGAAGATGTTGATGCAAGCCTTCTTGA
AGCGCTTAAACAACGTTTGAACTCCCAGTACAGTGAAAACGATTACCGTGCGGTTATCGCGTCTCTAAAGGCTAAGGGTG
AAGTACTTTACCCAGTTGCTGAGTAA

Upstream 100 bases:

>100_bases
TGAAGATTTTGGTATTTTCTCCTCCTTTAAATTACAAAAAGGCGCATCCAAACAGTGATGCGCCTTTTTATTATATTAAT
CGCAACAAGCGAGAAGTCTG

Downstream 100 bases:

>100_bases
GAGCTACTGAGTCAGCACTACTGAATAAATAGAAGTGAGTCTCATATGAGGCAATAAAAAACCGGCTGAAGCCGGTTTTT
TTATGGACGTGTATTAGCTA

Product: PpiC-type peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: PPIase D; Rotamase D [H]

Number of amino acids: Translated: 621; Mature: 621

Protein sequence:

>621_residues
MLEKIREGSQGVIAKSILVLVILSFAFTGVSSYLGSSTEVAAATVNGEEISNSALEQAYQNERSRLEQQLGDMFATLSAD
DNYMQSVKQSVLERLVAETLLDQNAAELGLRVSDEQIKAAIMTEPAFQTDGRFDNDRYQAILRQLGYQANSFRDMMRTDM
TRRQLVATLVGSEFVLPGEAKYLADLQGQTRDIDYKVIDATPFLADISVTDEQIKTYYDSNLDQFIRPEVVSLDYIELDA
KDLAKDVKVTDADAQAYYDEHKANYTQAEKRLAAHILVQAGDDDAAAKAKAEAIYKQLQDGADFAELAKTESEDTFSGEQ
GGQLDWFEAGVMEPEFDTALFALNKGDYSNVVKTNFGYHIIKLLDIQAGAEAPFADVKEKIIAQLQEKQAVDKFYELQQV
LADTSYEVPDTLVDAAKDLGVEVKTTVEFARTNPPELFSNPDLLKEAFSSNVLLDGMNSDVLEVEPNHVVVIRVNTHKAA
GTMDLADVRNAIANRLKQEQANEAARKQAQELMTAVEASGVTSDFIVKDKLARFEQDVDGAIVNKAFSMAQPSDKASVDT
VALANGYAVVVLKQVNAAEDVDASLLEALKQRLNSQYSENDYRAVIASLKAKGEVLYPVAE

Sequences:

>Translated_621_residues
MLEKIREGSQGVIAKSILVLVILSFAFTGVSSYLGSSTEVAAATVNGEEISNSALEQAYQNERSRLEQQLGDMFATLSAD
DNYMQSVKQSVLERLVAETLLDQNAAELGLRVSDEQIKAAIMTEPAFQTDGRFDNDRYQAILRQLGYQANSFRDMMRTDM
TRRQLVATLVGSEFVLPGEAKYLADLQGQTRDIDYKVIDATPFLADISVTDEQIKTYYDSNLDQFIRPEVVSLDYIELDA
KDLAKDVKVTDADAQAYYDEHKANYTQAEKRLAAHILVQAGDDDAAAKAKAEAIYKQLQDGADFAELAKTESEDTFSGEQ
GGQLDWFEAGVMEPEFDTALFALNKGDYSNVVKTNFGYHIIKLLDIQAGAEAPFADVKEKIIAQLQEKQAVDKFYELQQV
LADTSYEVPDTLVDAAKDLGVEVKTTVEFARTNPPELFSNPDLLKEAFSSNVLLDGMNSDVLEVEPNHVVVIRVNTHKAA
GTMDLADVRNAIANRLKQEQANEAARKQAQELMTAVEASGVTSDFIVKDKLARFEQDVDGAIVNKAFSMAQPSDKASVDT
VALANGYAVVVLKQVNAAEDVDASLLEALKQRLNSQYSENDYRAVIASLKAKGEVLYPVAE
>Mature_621_residues
MLEKIREGSQGVIAKSILVLVILSFAFTGVSSYLGSSTEVAAATVNGEEISNSALEQAYQNERSRLEQQLGDMFATLSAD
DNYMQSVKQSVLERLVAETLLDQNAAELGLRVSDEQIKAAIMTEPAFQTDGRFDNDRYQAILRQLGYQANSFRDMMRTDM
TRRQLVATLVGSEFVLPGEAKYLADLQGQTRDIDYKVIDATPFLADISVTDEQIKTYYDSNLDQFIRPEVVSLDYIELDA
KDLAKDVKVTDADAQAYYDEHKANYTQAEKRLAAHILVQAGDDDAAAKAKAEAIYKQLQDGADFAELAKTESEDTFSGEQ
GGQLDWFEAGVMEPEFDTALFALNKGDYSNVVKTNFGYHIIKLLDIQAGAEAPFADVKEKIIAQLQEKQAVDKFYELQQV
LADTSYEVPDTLVDAAKDLGVEVKTTVEFARTNPPELFSNPDLLKEAFSSNVLLDGMNSDVLEVEPNHVVVIRVNTHKAA
GTMDLADVRNAIANRLKQEQANEAARKQAQELMTAVEASGVTSDFIVKDKLARFEQDVDGAIVNKAFSMAQPSDKASVDT
VALANGYAVVVLKQVNAAEDVDASLLEALKQRLNSQYSENDYRAVIASLKAKGEVLYPVAE

Specific function: PPIases accelerate the folding of proteins. Seems to be involved in the folding of outer membrane proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein; Periplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1786645, Length=633, Percent_Identity=32.7014218009479, Blast_Score=337, Evalue=2e-93,
Organism=Escherichia coli, GI1786238, Length=96, Percent_Identity=40.625, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 68351; Mature: 68351

Theoretical pI: Translated: 4.22; Mature: 4.22

Prosite motif: PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEKIREGSQGVIAKSILVLVILSFAFTGVSSYLGSSTEVAAATVNGEEISNSALEQAYQ
CCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHH
NERSRLEQQLGDMFATLSADDNYMQSVKQSVLERLVAETLLDQNAAELGLRVSDEQIKAA
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCEECHHHHHHH
IMTEPAFQTDGRFDNDRYQAILRQLGYQANSFRDMMRTDMTRRQLVATLVGSEFVLPGEA
HHCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCH
KYLADLQGQTRDIDYKVIDATPFLADISVTDEQIKTYYDSNLDQFIRPEVVSLDYIELDA
HHHHHCCCCCCCCCEEEEECCCCEEECCCCHHHHHHHHHCCHHHHHCCCCEEEEEEECCH
KDLAKDVKVTDADAQAYYDEHKANYTQAEKRLAAHILVQAGDDDAAAKAKAEAIYKQLQD
HHHHHHCEECCCHHHHHHHHHHCCHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHC
GADFAELAKTESEDTFSGEQGGQLDWFEAGVMEPEFDTALFALNKGDYSNVVKTNFGYHI
CCCHHHHHHCCCCCCCCCCCCCCCCHHHCCCCCCCCCCEEEEECCCCCCCHHHCCCCEEE
IKLLDIQAGAEAPFADVKEKIIAQLQEKQAVDKFYELQQVLADTSYEVPDTLVDAAKDLG
EEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCC
VEVKTTVEFARTNPPELFSNPDLLKEAFSSNVLLDGMNSDVLEVEPNHVVVIRVNTHKAA
CEEEEHHHHHCCCCHHHCCCHHHHHHHHCCCEEEECCCCCEEEECCCEEEEEEEECCCCC
GTMDLADVRNAIANRLKQEQANEAARKQAQELMTAVEASGVTSDFIVKDKLARFEQDVDG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCH
AIVNKAFSMAQPSDKASVDTVALANGYAVVVLKQVNAAEDVDASLLEALKQRLNSQYSEN
HHHHHHHHHCCCCCCCCCCEEEEECCEEEEEEEECCCCCCCCHHHHHHHHHHHCCCCCCC
DYRAVIASLKAKGEVLYPVAE
HHHHHHHHHHCCCCEEECCCC
>Mature Secondary Structure
MLEKIREGSQGVIAKSILVLVILSFAFTGVSSYLGSSTEVAAATVNGEEISNSALEQAYQ
CCCCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHHH
NERSRLEQQLGDMFATLSADDNYMQSVKQSVLERLVAETLLDQNAAELGLRVSDEQIKAA
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCEECHHHHHHH
IMTEPAFQTDGRFDNDRYQAILRQLGYQANSFRDMMRTDMTRRQLVATLVGSEFVLPGEA
HHCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCH
KYLADLQGQTRDIDYKVIDATPFLADISVTDEQIKTYYDSNLDQFIRPEVVSLDYIELDA
HHHHHCCCCCCCCCEEEEECCCCEEECCCCHHHHHHHHHCCHHHHHCCCCEEEEEEECCH
KDLAKDVKVTDADAQAYYDEHKANYTQAEKRLAAHILVQAGDDDAAAKAKAEAIYKQLQD
HHHHHHCEECCCHHHHHHHHHHCCHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHC
GADFAELAKTESEDTFSGEQGGQLDWFEAGVMEPEFDTALFALNKGDYSNVVKTNFGYHI
CCCHHHHHHCCCCCCCCCCCCCCCCHHHCCCCCCCCCCEEEEECCCCCCCHHHCCCCEEE
IKLLDIQAGAEAPFADVKEKIIAQLQEKQAVDKFYELQQVLADTSYEVPDTLVDAAKDLG
EEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCC
VEVKTTVEFARTNPPELFSNPDLLKEAFSSNVLLDGMNSDVLEVEPNHVVVIRVNTHKAA
CEEEEHHHHHCCCCHHHCCCHHHHHHHHCCCEEEECCCCCEEEECCCEEEEEEEECCCCC
GTMDLADVRNAIANRLKQEQANEAARKQAQELMTAVEASGVTSDFIVKDKLARFEQDVDG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCH
AIVNKAFSMAQPSDKASVDTVALANGYAVVVLKQVNAAEDVDASLLEALKQRLNSQYSEN
HHHHHHHHHCCCCCCCCCCEEEEECCEEEEEEEECCCCCCCCHHHHHHHHHHHCCCCCCC
DYRAVIASLKAKGEVLYPVAE
HHHHHHHHHHCCCCEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]