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The map label for this gene is ycbL [H]

Identifier: 167624548

GI number: 167624548

Start: 3185725

End: 3186369

Strand: Reverse

Name: ycbL [H]

Synonym: Shal_2627

Alternate gene names: 167624548

Gene position: 3186369-3185725 (Counterclockwise)

Preceding gene: 167624551

Following gene: 167624547

Centisome position: 60.96

GC content: 44.34

Gene sequence:

>645_bases
ATGAAGTATCAGTTAATACCCGTCACTCCATTTCAGCAAAATTGTAGTTTAATCTGGTGCGAGCAAACCATGAAAGCGGC
CGTGGTCGACCCTGGTGGCAATGTCGAGCGGATCCTTGAACAGGCCAGTAAAAATAATCTGGTGATTGAAAAAGTATTAC
TGACCCATGGCCATATTGACCATGTCGGTGGCGCTAAATTGTTAGCCGATCAGCTTAATGTGCCGATTATTGGCCCCCAT
AAAGCGGATGATTACTGGCTAGAGAGCTTACCAAAACAGAGTCAACACTTTGGTTTTGTGCATTGCGATGCTTTTACGCC
GACACAATATCTCGAAGAGGGTGATGAAGTCACAGTGGGTCAGCAAGTGCTTAAAGTGATCCATACACCTGGTCATACTC
CTGGTCATATCGTGTTTTTTGCTAAAGAGAGTAAGGTCGCTTGGGTTGGTGATGTATTGTTTAGAGGCTCTATTGGTAGA
ACCGATTTCCCATTGTCTAATCATCAAGATTTAATTGACTCTATCACCCAAAAGCTTTGGCCTTTAGGTAACGATGTGCA
ATTTATTCCAGGCCATGGGCCACTATCGACTTTTGGTGATGAGCGAGTGCAAAACCCATTTGTTGCCGACCAGCTGTTTG
TCTAA

Upstream 100 bases:

>100_bases
GCGTTAGATCAAATTATCCTAATTATAAATAGTCGAAGAGCCCAACATGGCGTAATCTTTACCCATTCACAGCGAAACAT
AGAGCCTTAGGTGATTATCG

Downstream 100 bases:

>100_bases
TGTTAATGCCAATTCATTAATGCCAAGTCGTTAATGTTAGTCCCTTTACCCAGTCATCATTTTACTATTACTGGGTAAAA
AAAGCGCCTAAAGGCGCTTT

Product: beta-lactamase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 214; Mature: 214

Protein sequence:

>214_residues
MKYQLIPVTPFQQNCSLIWCEQTMKAAVVDPGGNVERILEQASKNNLVIEKVLLTHGHIDHVGGAKLLADQLNVPIIGPH
KADDYWLESLPKQSQHFGFVHCDAFTPTQYLEEGDEVTVGQQVLKVIHTPGHTPGHIVFFAKESKVAWVGDVLFRGSIGR
TDFPLSNHQDLIDSITQKLWPLGNDVQFIPGHGPLSTFGDERVQNPFVADQLFV

Sequences:

>Translated_214_residues
MKYQLIPVTPFQQNCSLIWCEQTMKAAVVDPGGNVERILEQASKNNLVIEKVLLTHGHIDHVGGAKLLADQLNVPIIGPH
KADDYWLESLPKQSQHFGFVHCDAFTPTQYLEEGDEVTVGQQVLKVIHTPGHTPGHIVFFAKESKVAWVGDVLFRGSIGR
TDFPLSNHQDLIDSITQKLWPLGNDVQFIPGHGPLSTFGDERVQNPFVADQLFV
>Mature_214_residues
MKYQLIPVTPFQQNCSLIWCEQTMKAAVVDPGGNVERILEQASKNNLVIEKVLLTHGHIDHVGGAKLLADQLNVPIIGPH
KADDYWLESLPKQSQHFGFVHCDAFTPTQYLEEGDEVTVGQQVLKVIHTPGHTPGHIVFFAKESKVAWVGDVLFRGSIGR
TDFPLSNHQDLIDSITQKLWPLGNDVQFIPGHGPLSTFGDERVQNPFVADQLFV

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family [H]

Homologues:

Organism=Homo sapiens, GI41327741, Length=201, Percent_Identity=27.363184079602, Blast_Score=70, Evalue=1e-12,
Organism=Escherichia coli, GI1787158, Length=214, Percent_Identity=54.6728971962617, Blast_Score=261, Evalue=4e-71,
Organism=Drosophila melanogaster, GI221330176, Length=197, Percent_Identity=25.3807106598985, Blast_Score=64, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279 [H]

Pfam domain/function: PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 23808; Mature: 23808

Theoretical pI: Translated: 5.92; Mature: 5.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYQLIPVTPFQQNCSLIWCEQTMKAAVVDPGGNVERILEQASKNNLVIEKVLLTHGHID
CCEEEEECCCCCCCCCEEEECCCCEEEEECCCCCHHHHHHHHCCCCEEEEHHHHHCCCCC
HVGGAKLLADQLNVPIIGPHKADDYWLESLPKQSQHFGFVHCDAFTPTQYLEEGDEVTVG
CCCCHHHHHHHCCCCEECCCCCCHHHHHHCCCCHHCCCEEEECCCCCHHHHHCCCCCHHH
QQVLKVIHTPGHTPGHIVFFAKESKVAWVGDVLFRGSIGRTDFPLSNHQDLIDSITQKLW
HHHHHHHHCCCCCCCEEEEEECCCCEEEEEHHHHCCCCCCCCCCCCCHHHHHHHHHHHHC
PLGNDVQFIPGHGPLSTFGDERVQNPFVADQLFV
CCCCCEEEECCCCCCCCCCHHHHCCCCCHHHHCC
>Mature Secondary Structure
MKYQLIPVTPFQQNCSLIWCEQTMKAAVVDPGGNVERILEQASKNNLVIEKVLLTHGHID
CCEEEEECCCCCCCCCEEEECCCCEEEEECCCCCHHHHHHHHCCCCEEEEHHHHHCCCCC
HVGGAKLLADQLNVPIIGPHKADDYWLESLPKQSQHFGFVHCDAFTPTQYLEEGDEVTVG
CCCCHHHHHHHCCCCEECCCCCCHHHHHHCCCCHHCCCEEEECCCCCHHHHHCCCCCHHH
QQVLKVIHTPGHTPGHIVFFAKESKVAWVGDVLFRGSIGRTDFPLSNHQDLIDSITQKLW
HHHHHHHHCCCCCCCEEEEEECCCCEEEEEHHHHCCCCCCCCCCCCCHHHHHHHHHHHHC
PLGNDVQFIPGHGPLSTFGDERVQNPFVADQLFV
CCCCCEEEECCCCCCCCCCHHHHCCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]