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The map label for this gene is gmhB [H]

Identifier: 167624468

GI number: 167624468

Start: 3083933

End: 3084472

Strand: Reverse

Name: gmhB [H]

Synonym: Shal_2547

Alternate gene names: 167624468

Gene position: 3084472-3083933 (Counterclockwise)

Preceding gene: 167624471

Following gene: 167624464

Centisome position: 59.01

GC content: 44.26

Gene sequence:

>540_bases
GTGTTTTTAGACAGAGATGGCGTTATCAATCTAGATCATGGTTATGTACACCAGGTTGATGATTTTGAATATGTAGACGG
TGTGTTTGATGCGTGCGCTGCACTTAAAGAGATGGGATATCTACTTGCAGTCGTTACCAACCAGTCTGGTATTGCTCGAG
GAATGTATAGTGAAGATCAGTTTCATTCATTAACGGAGTGGATGGATTGGAACTTTGTTGATAAAGGTGTTGAGCTTGAT
GGCATCTATTACTGCCCACATCATGCTGAAAAGGGCATTGGCGAATACAAAATCGATTGTGACTGCCGTAAACCGAAACC
TGGCATGCTTAACTCGGCGGCACAGTTTTTAAAAATCGATCTGTCTCAGTCGGTCATGGTGGGTGATAAACGAGATGATA
TGTTAGCAGCAGAGGCTGCAGGCGTACCGACACGCATTCTTGTTAGAACCGGCAAGTCAGTAACAGATGACGCGATTGCG
GCTGCAACTGTGGTGTTAGATTCAATTGCAGATGTTCCTGCATATCTAGCAAGCAGATAG

Upstream 100 bases:

>100_bases
ATATTACTTGCTATATAGCAAGTTCACGGTGCAATTTGTTGTAATGAGTGAAATAATAATAGCCATTGCATATTAGAGAG
AATGTATTGTGAATCGAGCG

Downstream 100 bases:

>100_bases
AAATTGATATAATAACAGCGCCTCTAGTAAGTAGTAGAACTAAATAGCAAACACGAAAATGCCCCATCTAGGGGCATTTT
CGTTATCAGCATTCGGTGAT

Product: D,D-heptose 1,7-bisphosphate phosphatase

Products: NA

Alternate protein names: D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase [H]

Number of amino acids: Translated: 179; Mature: 179

Protein sequence:

>179_residues
MFLDRDGVINLDHGYVHQVDDFEYVDGVFDACAALKEMGYLLAVVTNQSGIARGMYSEDQFHSLTEWMDWNFVDKGVELD
GIYYCPHHAEKGIGEYKIDCDCRKPKPGMLNSAAQFLKIDLSQSVMVGDKRDDMLAAEAAGVPTRILVRTGKSVTDDAIA
AATVVLDSIADVPAYLASR

Sequences:

>Translated_179_residues
MFLDRDGVINLDHGYVHQVDDFEYVDGVFDACAALKEMGYLLAVVTNQSGIARGMYSEDQFHSLTEWMDWNFVDKGVELD
GIYYCPHHAEKGIGEYKIDCDCRKPKPGMLNSAAQFLKIDLSQSVMVGDKRDDMLAAEAAGVPTRILVRTGKSVTDDAIA
AATVVLDSIADVPAYLASR
>Mature_179_residues
MFLDRDGVINLDHGYVHQVDDFEYVDGVFDACAALKEMGYLLAVVTNQSGIARGMYSEDQFHSLTEWMDWNFVDKGVELD
GIYYCPHHAEKGIGEYKIDCDCRKPKPGMLNSAAQFLKIDLSQSVMVGDKRDDMLAAEAAGVPTRILVRTGKSVTDDAIA
AATVVLDSIADVPAYLASR

Specific function: Converts the D-glycero-beta-D-manno-heptose 1,7- bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1- phosphate by removing the phosphate group at the C-7 position [H]

COG id: COG0241

COG function: function code E; Histidinol phosphatase and related phosphatases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gmhB family [H]

Homologues:

Organism=Escherichia coli, GI1786399, Length=179, Percent_Identity=59.2178770949721, Blast_Score=232, Evalue=9e-63,
Organism=Escherichia coli, GI87082027, Length=145, Percent_Identity=29.6551724137931, Blast_Score=73, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006549
- InterPro:   IPR004446
- InterPro:   IPR006543 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: 3.1.1.-

Molecular weight: Translated: 19702; Mature: 19702

Theoretical pI: Translated: 4.39; Mature: 4.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFLDRDGVINLDHGYVHQVDDFEYVDGVFDACAALKEMGYLLAVVTNQSGIARGMYSEDQ
CCCCCCCEEECCCCCEECCCCHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCHH
FHSLTEWMDWNFVDKGVELDGIYYCPHHAEKGIGEYKIDCDCRKPKPGMLNSAAQFLKID
HHHHHHHHCCCCCCCCCCCCEEEECCCHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHHC
LSQSVMVGDKRDDMLAAEAAGVPTRILVRTGKSVTDDAIAAATVVLDSIADVPAYLASR
CCCCEEECCCCCCHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MFLDRDGVINLDHGYVHQVDDFEYVDGVFDACAALKEMGYLLAVVTNQSGIARGMYSEDQ
CCCCCCCEEECCCCCEECCCCHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCCHH
FHSLTEWMDWNFVDKGVELDGIYYCPHHAEKGIGEYKIDCDCRKPKPGMLNSAAQFLKID
HHHHHHHHCCCCCCCCCCCCEEEECCCHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHHC
LSQSVMVGDKRDDMLAAEAAGVPTRILVRTGKSVTDDAIAAATVVLDSIADVPAYLASR
CCCCEEECCCCCCHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301; 12101286 [H]