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The map label for this gene is pepV [H]

Identifier: 167624352

GI number: 167624352

Start: 2932445

End: 2933959

Strand: Reverse

Name: pepV [H]

Synonym: Shal_2429

Alternate gene names: 167624352

Gene position: 2933959-2932445 (Counterclockwise)

Preceding gene: 167624354

Following gene: 167624351

Centisome position: 56.13

GC content: 46.27

Gene sequence:

>1515_bases
ATGAGAGTCCTTCCCTACCTTATCGCCCCTTTGTTGGCATCGACGCTGTTATCACCCTCAGTATTGGCGGTTTCACCTCT
ATCGCAAAAGGTCGCCGATTACGCGGTTGATAACTATTCTAAACCGATGGTCGAGAATCTCGCCAACTTAGTGCGTTTTA
ATACACAAGCTGTAGAAGGATTGACTCCCGACACCAACCCTGAATTTATAGGCTTTAAAGCTGAACTTAAGGCATTGAGC
CATAGGTTAGGATTAGACTATAGCGATCATGGTTATGTTGTACTTATTGGCCTTGGACAGAGTGAGGAGAAACTTGGCGT
AATTACCCATGGGGATGTGCAGCCTGCAGATCCTGAGCTCTGGTTGCAGAGTCCCTATATTCTGGATACGCAATCTGAGC
CGGGTAAACTTATTGGTCGCGGCACCGAGGATGACAAGGGGCCGATAGTGACCGCCATGTACGCAATGAAGTCGATAAAA
GACAATGATATTCGCTTAAATAAGCGTATAGAGTTAATGGTCTATATGGCCGAGGAGTCAGATTGGCAGCCGTTGAGAGA
TTTCTTACAAAGTTATACCCCCGCAAACATAAATATCACCATCGATGCCGAATATCCTGTGGTTACCGCGGAAAAAGGTT
GGAGTCAAATTGCCTTTACCATCCCCAATATCCAATCAGACTCAACGACGAGTGAACCTCAACTGCTCGAATTTAATGGT
GGCTCATTTGCAAGTCAAGTGCCACAGCAAGCGTTTGCTAAGCTTATCAATGTGAATAGTGAACTGCTCGCGGCGTTTAA
AAAGAAGGCCGAATTACAACCACAGATGAGGTATCGCTTTAAGCAAACTCAGGAGAGTTTAACTATTTTTGCCGATGGTA
AGTCTACGCACTCCTCAACGCCTGAAGACGGTATAAATGCGGTTACTCATCTTGCAGAGTTACTTTCAATCCGCACTTGG
CCCAAATCGACAGCATCGTTAACCCAGAAATTTATTGATGACATGGTCGGTTTAGGTCACTACGGTGAACAATTTGGTGA
TATTGCTTATAAAGATGAGTTTATGGGCGCGATGAGCCTAGCCCCGACGGTGGTCAAACAAGGCGTCGCAGGCACTAAGA
TCACCATTAACCTTCGCCGCCCTAAAGGTAAAACGGCTGAGCTTCTGGATGAGCAAACTCTCTTTGCAATGGCGCGTTGG
CAGGCTAACAATCATGTCCAGTTAGTGGGGATTGATACTTACTGGGGGAAACCTATGGTGATGGAGGGTGCTCCACACTT
GGAGACCTTACTGAGTATCTTTGGTCACTATACCGATACTGATAACCCACAACCTGTCGCTATCGGCGGCTCGACCAACA
GTAAACTATTCCCCAATGCCTTGAGTTTTGGTCCCGCTATGCCGGGCGTTGAATACACGGGACACAGTGAAAATGAGTTT
ATTACTTACCAACAATTTATGCTGAACTTAAAGATGTACACTGCGGCATTTATCGAACTCGCGGCGAGCCAGTAA

Upstream 100 bases:

>100_bases
ATTTGTAACAAAGCGTACTCCTAGCTATTTTTTGTACATTTATAGGGTTGTTTTATGGCATGCTAGCCTGAGTTTTATTG
ATAATCATAAATGGAATACC

Downstream 100 bases:

>100_bases
CGATACACAGTCATGACAGGAGTTTAAACCCCGGATCATGACCGTGTGTGTGAGTAAAGTGTTTGCTAAAGTTCGTGATA
CAGCGTTTTATTAACAATGT

Product: hypothetical protein

Products: NA

Alternate protein names: Beta-Ala-His dipeptidase; Peptidase V [H]

Number of amino acids: Translated: 504; Mature: 504

Protein sequence:

>504_residues
MRVLPYLIAPLLASTLLSPSVLAVSPLSQKVADYAVDNYSKPMVENLANLVRFNTQAVEGLTPDTNPEFIGFKAELKALS
HRLGLDYSDHGYVVLIGLGQSEEKLGVITHGDVQPADPELWLQSPYILDTQSEPGKLIGRGTEDDKGPIVTAMYAMKSIK
DNDIRLNKRIELMVYMAEESDWQPLRDFLQSYTPANINITIDAEYPVVTAEKGWSQIAFTIPNIQSDSTTSEPQLLEFNG
GSFASQVPQQAFAKLINVNSELLAAFKKKAELQPQMRYRFKQTQESLTIFADGKSTHSSTPEDGINAVTHLAELLSIRTW
PKSTASLTQKFIDDMVGLGHYGEQFGDIAYKDEFMGAMSLAPTVVKQGVAGTKITINLRRPKGKTAELLDEQTLFAMARW
QANNHVQLVGIDTYWGKPMVMEGAPHLETLLSIFGHYTDTDNPQPVAIGGSTNSKLFPNALSFGPAMPGVEYTGHSENEF
ITYQQFMLNLKMYTAAFIELAASQ

Sequences:

>Translated_504_residues
MRVLPYLIAPLLASTLLSPSVLAVSPLSQKVADYAVDNYSKPMVENLANLVRFNTQAVEGLTPDTNPEFIGFKAELKALS
HRLGLDYSDHGYVVLIGLGQSEEKLGVITHGDVQPADPELWLQSPYILDTQSEPGKLIGRGTEDDKGPIVTAMYAMKSIK
DNDIRLNKRIELMVYMAEESDWQPLRDFLQSYTPANINITIDAEYPVVTAEKGWSQIAFTIPNIQSDSTTSEPQLLEFNG
GSFASQVPQQAFAKLINVNSELLAAFKKKAELQPQMRYRFKQTQESLTIFADGKSTHSSTPEDGINAVTHLAELLSIRTW
PKSTASLTQKFIDDMVGLGHYGEQFGDIAYKDEFMGAMSLAPTVVKQGVAGTKITINLRRPKGKTAELLDEQTLFAMARW
QANNHVQLVGIDTYWGKPMVMEGAPHLETLLSIFGHYTDTDNPQPVAIGGSTNSKLFPNALSFGPAMPGVEYTGHSENEF
ITYQQFMLNLKMYTAAFIELAASQ
>Mature_504_residues
MRVLPYLIAPLLASTLLSPSVLAVSPLSQKVADYAVDNYSKPMVENLANLVRFNTQAVEGLTPDTNPEFIGFKAELKALS
HRLGLDYSDHGYVVLIGLGQSEEKLGVITHGDVQPADPELWLQSPYILDTQSEPGKLIGRGTEDDKGPIVTAMYAMKSIK
DNDIRLNKRIELMVYMAEESDWQPLRDFLQSYTPANINITIDAEYPVVTAEKGWSQIAFTIPNIQSDSTTSEPQLLEFNG
GSFASQVPQQAFAKLINVNSELLAAFKKKAELQPQMRYRFKQTQESLTIFADGKSTHSSTPEDGINAVTHLAELLSIRTW
PKSTASLTQKFIDDMVGLGHYGEQFGDIAYKDEFMGAMSLAPTVVKQGVAGTKITINLRRPKGKTAELLDEQTLFAMARW
QANNHVQLVGIDTYWGKPMVMEGAPHLETLLSIFGHYTDTDNPQPVAIGGSTNSKLFPNALSFGPAMPGVEYTGHSENEF
ITYQQFMLNLKMYTAAFIELAASQ

Specific function: Is a relatively unspecific dipeptidase cleaving a variety of dipeptides, notably those with an N-terminal beta-Ala or D-Ala residue, e.g. carnosine (beta-Ala-His). To a lesser extent, also shows aminopeptidase activity, since it is able to catalyze the re

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001261
- InterPro:   IPR011291
- InterPro:   IPR010964
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF01546 Peptidase_M20 [H]

EC number: 3.4.13.3

Molecular weight: Translated: 55656; Mature: 55656

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVLPYLIAPLLASTLLSPSVLAVSPLSQKVADYAVDNYSKPMVENLANLVRFNTQAVEG
CCCHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHCC
LTPDTNPEFIGFKAELKALSHRLGLDYSDHGYVVLIGLGQSEEKLGVITHGDVQPADPEL
CCCCCCCCEEEHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCEEEEEECCCCCCCCCC
WLQSPYILDTQSEPGKLIGRGTEDDKGPIVTAMYAMKSIKDNDIRLNKRIELMVYMAEES
EECCCEEEECCCCCCCEEECCCCCCCCCEEHHHHHHHHCCCCCEEECCEEEEEEEEECCC
DWQPLRDFLQSYTPANINITIDAEYPVVTAEKGWSQIAFTIPNIQSDSTTSEPQLLEFNG
CCHHHHHHHHHCCCCCEEEEEECCCCEEECCCCCCEEEEEECCCCCCCCCCCCEEEEECC
GSFASQVPQQAFAKLINVNSELLAAFKKKAELQPQMRYRFKQTQESLTIFADGKSTHSST
CCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEEECCCCCCCCC
PEDGINAVTHLAELLSIRTWPKSTASLTQKFIDDMVGLGHYGEQFGDIAYKDEFMGAMSL
CHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHH
APTVVKQGVAGTKITINLRRPKGKTAELLDEQTLFAMARWQANNHVQLVGIDTYWGKPMV
HHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCEE
MEGAPHLETLLSIFGHYTDTDNPQPVAIGGSTNSKLFPNALSFGPAMPGVEYTGHSENEF
ECCCCHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCHHHCCCCCCCCEECCCCCCCE
ITYQQFMLNLKMYTAAFIELAASQ
EEHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRVLPYLIAPLLASTLLSPSVLAVSPLSQKVADYAVDNYSKPMVENLANLVRFNTQAVEG
CCCHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHCC
LTPDTNPEFIGFKAELKALSHRLGLDYSDHGYVVLIGLGQSEEKLGVITHGDVQPADPEL
CCCCCCCCEEEHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCEEEEEECCCCCCCCCC
WLQSPYILDTQSEPGKLIGRGTEDDKGPIVTAMYAMKSIKDNDIRLNKRIELMVYMAEES
EECCCEEEECCCCCCCEEECCCCCCCCCEEHHHHHHHHCCCCCEEECCEEEEEEEEECCC
DWQPLRDFLQSYTPANINITIDAEYPVVTAEKGWSQIAFTIPNIQSDSTTSEPQLLEFNG
CCHHHHHHHHHCCCCCEEEEEECCCCEEECCCCCCEEEEEECCCCCCCCCCCCEEEEECC
GSFASQVPQQAFAKLINVNSELLAAFKKKAELQPQMRYRFKQTQESLTIFADGKSTHSST
CCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCEEEEECCCCCCCCC
PEDGINAVTHLAELLSIRTWPKSTASLTQKFIDDMVGLGHYGEQFGDIAYKDEFMGAMSL
CHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHHHHH
APTVVKQGVAGTKITINLRRPKGKTAELLDEQTLFAMARWQANNHVQLVGIDTYWGKPMV
HHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCEE
MEGAPHLETLLSIFGHYTDTDNPQPVAIGGSTNSKLFPNALSFGPAMPGVEYTGHSENEF
ECCCCHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCHHHCCCCCCCCEECCCCCCCE
ITYQQFMLNLKMYTAAFIELAASQ
EEHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7528082 [H]