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The map label for this gene is ycfH [H]

Identifier: 167624297

GI number: 167624297

Start: 2874503

End: 2875291

Strand: Reverse

Name: ycfH [H]

Synonym: Shal_2373

Alternate gene names: 167624297

Gene position: 2875291-2874503 (Counterclockwise)

Preceding gene: 167624298

Following gene: 167624295

Centisome position: 55.01

GC content: 43.09

Gene sequence:

>789_bases
GTGCTTATCGATTCACATTGTCATTTAGACCGTCTAAAAACCGCGCCTGATCAGGCTTCATTACAAGAGATCATTACCGC
TGCAAAAGCACGTGATATTGCTTATTTTCTTTGTGTGAATGTTAGGCAGCAAGGTTTTATCGAGATGAAGCAAAAAATGG
CGGCCTTTGATGAGGTCTTTCTGTCTGCTGGTGTACACCCACTAGATGTACAAGACGGCTTAAATATCGAAGAAGTTGAG
CTGTTTGCGCATGATGAGAAAGTGATCGCTATTGGCGAAACTGGTCTCGATTACTTTTATGCTAATGAGACAAAAGCACT
GCAACAAACCTGTTTTGAGCAACAGATTGATCTCGCTGTAAAGGTTAACAAGCCCCTTATTATTCATACCCGCGATGCAC
GTGAAGACACCATTAATTTTTTAAAGCGGGGCAATGCCGACTCGGTTGGCGGCGTCTTGCACTGTTTTACTGAAAGCTGG
GAAATGGCGAAAGAAGCTTTAGATTTAGGCTTTTACATCTCTGTGTCCGGCATTGTTACTTTTAAAAATGCCGGTGAGCT
TCGTAATGTGATCCGCAAGGTACCAAAAGATAGATTATTGGTAGAGACGGACTCTCCTTATTTAGCACCCGTTCCTCACC
GTGGTAAAGAAAATCAACCTGCATTTGTACGTGATGTGGCGGAATTTGTCGCCGAGCTAAGAGGTGAGAAATATCCTGAA
TTGGCTCAGTATACAACGGACAATTTTTTTACTTTGTTTAAAGATGCAGCAAGGCTCGCTGGGCGCTAA

Upstream 100 bases:

>100_bases
CGAGCAACTCCTTTCTCGCGAACTGGCATCAGGAGATTTGACCTGCACTATGTAGCTGGTTAGACTTGCTGTCCTTTTTG
TTGTTTGTTGGATTTTCACC

Downstream 100 bases:

>100_bases
CTGTAATGCGGCGTAATTAACTGCTCAGGCAGAAGCTAAATTACAGGCAAAAAAAGACCCAAAACTATTCCAATTGTTCT
GGGTCTAGGGGAATGGCTCA

Product: TatD family hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 262; Mature: 262

Protein sequence:

>262_residues
MLIDSHCHLDRLKTAPDQASLQEIITAAKARDIAYFLCVNVRQQGFIEMKQKMAAFDEVFLSAGVHPLDVQDGLNIEEVE
LFAHDEKVIAIGETGLDYFYANETKALQQTCFEQQIDLAVKVNKPLIIHTRDAREDTINFLKRGNADSVGGVLHCFTESW
EMAKEALDLGFYISVSGIVTFKNAGELRNVIRKVPKDRLLVETDSPYLAPVPHRGKENQPAFVRDVAEFVAELRGEKYPE
LAQYTTDNFFTLFKDAARLAGR

Sequences:

>Translated_262_residues
MLIDSHCHLDRLKTAPDQASLQEIITAAKARDIAYFLCVNVRQQGFIEMKQKMAAFDEVFLSAGVHPLDVQDGLNIEEVE
LFAHDEKVIAIGETGLDYFYANETKALQQTCFEQQIDLAVKVNKPLIIHTRDAREDTINFLKRGNADSVGGVLHCFTESW
EMAKEALDLGFYISVSGIVTFKNAGELRNVIRKVPKDRLLVETDSPYLAPVPHRGKENQPAFVRDVAEFVAELRGEKYPE
LAQYTTDNFFTLFKDAARLAGR
>Mature_262_residues
MLIDSHCHLDRLKTAPDQASLQEIITAAKARDIAYFLCVNVRQQGFIEMKQKMAAFDEVFLSAGVHPLDVQDGLNIEEVE
LFAHDEKVIAIGETGLDYFYANETKALQQTCFEQQIDLAVKVNKPLIIHTRDAREDTINFLKRGNADSVGGVLHCFTESW
EMAKEALDLGFYISVSGIVTFKNAGELRNVIRKVPKDRLLVETDSPYLAPVPHRGKENQPAFVRDVAEFVAELRGEKYPE
LAQYTTDNFFTLFKDAARLAGR

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI225903424, Length=225, Percent_Identity=32.8888888888889, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI110349730, Length=268, Percent_Identity=27.6119402985075, Blast_Score=99, Evalue=5e-21,
Organism=Homo sapiens, GI110349734, Length=268, Percent_Identity=27.6119402985075, Blast_Score=95, Evalue=6e-20,
Organism=Homo sapiens, GI226061853, Length=275, Percent_Identity=27.2727272727273, Blast_Score=95, Evalue=8e-20,
Organism=Homo sapiens, GI226061614, Length=258, Percent_Identity=28.2945736434109, Blast_Score=92, Evalue=6e-19,
Organism=Homo sapiens, GI14042943, Length=274, Percent_Identity=25.5474452554745, Blast_Score=85, Evalue=8e-17,
Organism=Homo sapiens, GI225903439, Length=232, Percent_Identity=27.1551724137931, Blast_Score=85, Evalue=8e-17,
Organism=Homo sapiens, GI226061595, Length=232, Percent_Identity=27.1551724137931, Blast_Score=78, Evalue=1e-14,
Organism=Escherichia coli, GI1787342, Length=259, Percent_Identity=54.0540540540541, Blast_Score=281, Evalue=3e-77,
Organism=Escherichia coli, GI87082439, Length=257, Percent_Identity=30.7392996108949, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI48994985, Length=224, Percent_Identity=35.2678571428571, Blast_Score=118, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI17559024, Length=277, Percent_Identity=29.2418772563177, Blast_Score=114, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI71980746, Length=267, Percent_Identity=30.7116104868914, Blast_Score=98, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17543026, Length=289, Percent_Identity=28.0276816608997, Blast_Score=88, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17565396, Length=218, Percent_Identity=29.3577981651376, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24586117, Length=285, Percent_Identity=29.4736842105263, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI221330018, Length=285, Percent_Identity=29.4736842105263, Blast_Score=92, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24648690, Length=229, Percent_Identity=30.1310043668122, Blast_Score=87, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 29525; Mature: 29525

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: PS01137 TATD_1 ; PS01090 TATD_2 ; PS01091 TATD_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIDSHCHLDRLKTAPDQASLQEIITAAKARDIAYFLCVNVRQQGFIEMKQKMAAFDEVF
CEECCCCCHHHHCCCCCHHHHHHHHHHHHHHHEEEEEEECCCHHHHHHHHHHHHHHHHHH
LSAGVHPLDVQDGLNIEEVELFAHDEKVIAIGETGLDYFYANETKALQQTCFEQQIDLAV
HHCCCCCCCCCCCCCHHHEEEEECCCEEEEEECCCCCEEECCCHHHHHHHHHHHHCCEEE
KVNKPLIIHTRDAREDTINFLKRGNADSVGGVLHCFTESWEMAKEALDLGFYISVSGIVT
EECCCEEEEECCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEEE
FKNAGELRNVIRKVPKDRLLVETDSPYLAPVPHRGKENQPAFVRDVAEFVAELRGEKYPE
ECCCHHHHHHHHHCCCCCEEEECCCCEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCH
LAQYTTDNFFTLFKDAARLAGR
HHHHCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLIDSHCHLDRLKTAPDQASLQEIITAAKARDIAYFLCVNVRQQGFIEMKQKMAAFDEVF
CEECCCCCHHHHCCCCCHHHHHHHHHHHHHHHEEEEEEECCCHHHHHHHHHHHHHHHHHH
LSAGVHPLDVQDGLNIEEVELFAHDEKVIAIGETGLDYFYANETKALQQTCFEQQIDLAV
HHCCCCCCCCCCCCCHHHEEEEECCCEEEEEECCCCCEEECCCHHHHHHHHHHHHCCEEE
KVNKPLIIHTRDAREDTINFLKRGNADSVGGVLHCFTESWEMAKEALDLGFYISVSGIVT
EECCCEEEEECCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEEE
FKNAGELRNVIRKVPKDRLLVETDSPYLAPVPHRGKENQPAFVRDVAEFVAELRGEKYPE
ECCCHHHHHHHHHCCCCCEEEECCCCEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCH
LAQYTTDNFFTLFKDAARLAGR
HHHHCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]