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The map label for this gene is kdsB

Identifier: 167624240

GI number: 167624240

Start: 2800840

End: 2801577

Strand: Direct

Name: kdsB

Synonym: Shal_2316

Alternate gene names: 167624240

Gene position: 2800840-2801577 (Clockwise)

Preceding gene: 167624239

Following gene: 167624241

Centisome position: 53.58

GC content: 46.21

Gene sequence:

>738_bases
ATGAATGTAACCTTATTAATCCCTGCTCGTTACGGCTCTAGCCGTTTCCCTGGCAAGCCATTGGCGCCTATTAACGGCAA
GCCAATGATCCAGCATGTCTACGAGCGCGCTGCTTTAGCAAAAGGGCTTAAAGACATCTATGTCGCCACCGATGATGAGC
GCATTAAAAACGCCGTAGAAGGTTTTGGTGGCAAAGTTGTTATGACAGGTGCAGATGCCGCATCGGGTACTGACCGTATC
GACGATGCAATCACCCAACTAGGGCTAGCTGATGACGATCTTGTGATTAACTTGCAAGGCGATCAACCCCTTATCGACCC
CATCTCTATTGAACAACTTGTTAGCCTTTGTGAGCGCCACCCAGGCGAATTTGATATGGCGACATTAGGTGTTGAAATTA
GAGACGAAGCTCAAATTAATGATCCAAACCATGTGAAAATGGTATTCGATAACAATTTTAATGCCCTCTATTTTTCTCGT
GCAACGATTCCCTTTGGTCGAGAGAGCAGCGATTACCCGGTATACAAGCATCTCGGTATTTACGCATATACGCGTAAATT
TATTCAGACTTTCGCTAAGCTGCCACTTGGCCGCCTAGAAGATCTCGAAAAACTTGAACAGCTTAGAGCACTCGAATACG
GCTACAAAATCAAAGTTGCCATCAGCGCATTCGATTCACCGGAAGTGGATACACCGGAAGATATCCGTATCTGCGAAGCC
AGACTTGCCGTTGACTAA

Upstream 100 bases:

>100_bases
AGATGCTAACTAAACTATTTCGTCGTATCTAAACTCTAGCGTAAGCATAGAATGGGCTTCAAAAAGAAGCCCATGATACT
TTTTTAAGTAGGTAAATTGA

Downstream 100 bases:

>100_bases
TTGAGGTTAAGTGATGTCAGATCTTGAAGTGGGTTTATTAATTTTATTGGTGCTCGGAGTGATCGCCAGTAATCTTGCGG
TCTTAAAGTACAGTGCTAAA

Product: 3-deoxy-manno-octulosonate cytidylyltransferase

Products: NA

Alternate protein names: CMP-2-keto-3-deoxyoctulosonic acid synthase; CKS; CMP-KDO synthase

Number of amino acids: Translated: 245; Mature: 245

Protein sequence:

>245_residues
MNVTLLIPARYGSSRFPGKPLAPINGKPMIQHVYERAALAKGLKDIYVATDDERIKNAVEGFGGKVVMTGADAASGTDRI
DDAITQLGLADDDLVINLQGDQPLIDPISIEQLVSLCERHPGEFDMATLGVEIRDEAQINDPNHVKMVFDNNFNALYFSR
ATIPFGRESSDYPVYKHLGIYAYTRKFIQTFAKLPLGRLEDLEKLEQLRALEYGYKIKVAISAFDSPEVDTPEDIRICEA
RLAVD

Sequences:

>Translated_245_residues
MNVTLLIPARYGSSRFPGKPLAPINGKPMIQHVYERAALAKGLKDIYVATDDERIKNAVEGFGGKVVMTGADAASGTDRI
DDAITQLGLADDDLVINLQGDQPLIDPISIEQLVSLCERHPGEFDMATLGVEIRDEAQINDPNHVKMVFDNNFNALYFSR
ATIPFGRESSDYPVYKHLGIYAYTRKFIQTFAKLPLGRLEDLEKLEQLRALEYGYKIKVAISAFDSPEVDTPEDIRICEA
RLAVD
>Mature_245_residues
MNVTLLIPARYGSSRFPGKPLAPINGKPMIQHVYERAALAKGLKDIYVATDDERIKNAVEGFGGKVVMTGADAASGTDRI
DDAITQLGLADDDLVINLQGDQPLIDPISIEQLVSLCERHPGEFDMATLGVEIRDEAQINDPNHVKMVFDNNFNALYFSR
ATIPFGRESSDYPVYKHLGIYAYTRKFIQTFAKLPLGRLEDLEKLEQLRALEYGYKIKVAISAFDSPEVDTPEDIRICEA
RLAVD

Specific function: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria

COG id: COG1212

COG function: function code M; CMP-2-keto-3-deoxyoctulosonic acid synthetase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsB family

Homologues:

Organism=Escherichia coli, GI1787147, Length=251, Percent_Identity=45.0199203187251, Blast_Score=195, Evalue=2e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KDSB_SHEHH (B0TVJ0)

Other databases:

- EMBL:   CP000931
- RefSeq:   YP_001674534.1
- ProteinModelPortal:   B0TVJ0
- SMR:   B0TVJ0
- GeneID:   5906584
- GenomeReviews:   CP000931_GR
- KEGG:   shl:Shal_2316
- HOGENOM:   HBG637773
- OMA:   IIPARLK
- ProtClustDB:   PRK05450
- BioCyc:   SHAL458817:SHAL_2316-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00057
- InterPro:   IPR003329
- InterPro:   IPR004528
- TIGRFAMs:   TIGR00466

Pfam domain/function: PF02348 CTP_transf_3

EC number: =2.7.7.38

Molecular weight: Translated: 27234; Mature: 27234

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVTLLIPARYGSSRFPGKPLAPINGKPMIQHVYERAALAKGLKDIYVATDDERIKNAVE
CCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHEEEECCHHHHHHHHH
GFGGKVVMTGADAASGTDRIDDAITQLGLADDDLVINLQGDQPLIDPISIEQLVSLCERH
CCCCEEEEECCCCCCCCHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHC
PGEFDMATLGVEIRDEAQINDPNHVKMVFDNNFNALYFSRATIPFGRESSDYPVYKHLGI
CCCCCEEEECEEEECCCCCCCCCEEEEEEECCCCEEEEEEEECCCCCCCCCCCHHHHHHH
YAYTRKFIQTFAKLPLGRLEDLEKLEQLRALEYGYKIKVAISAFDSPEVDTPEDIRICEA
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCHHHHHHHH
RLAVD
EECCC
>Mature Secondary Structure
MNVTLLIPARYGSSRFPGKPLAPINGKPMIQHVYERAALAKGLKDIYVATDDERIKNAVE
CCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHEEEECCHHHHHHHHH
GFGGKVVMTGADAASGTDRIDDAITQLGLADDDLVINLQGDQPLIDPISIEQLVSLCERH
CCCCEEEEECCCCCCCCHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHC
PGEFDMATLGVEIRDEAQINDPNHVKMVFDNNFNALYFSRATIPFGRESSDYPVYKHLGI
CCCCCEEEECEEEECCCCCCCCCEEEEEEECCCCEEEEEEEECCCCCCCCCCCHHHHHHH
YAYTRKFIQTFAKLPLGRLEDLEKLEQLRALEYGYKIKVAISAFDSPEVDTPEDIRICEA
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCHHHHHHHH
RLAVD
EECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA