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The map label for this gene is ushA [H]

Identifier: 167624150

GI number: 167624150

Start: 2693235

End: 2694971

Strand: Reverse

Name: ushA [H]

Synonym: Shal_2226

Alternate gene names: 167624150

Gene position: 2694971-2693235 (Counterclockwise)

Preceding gene: 167624151

Following gene: 167624147

Centisome position: 51.56

GC content: 42.77

Gene sequence:

>1737_bases
ATGATGAGATGTACTATGCGTGTTAATTATATCGGCAGCGTATCTGTCATAGCGGTCATACTGCTGTCTGGGTGTGGAAT
TAACCAAAAAAGTTTTGCAACATGTGCAGCAGCAGGCGATGCTTGTACTCGATTCACCATTTTGCATACCAATGACAACC
ATGGTCGCTTTTGGGAAAATAAACATGGTGAATATGGTATGGCTGCACGTAAAACTTTGATTGATTCAATCCGCCAAGAG
GTTAATGCGCAGGGGGAGCACGTATTGCTTTTTTCTGGCGGTGATATTAATACCGGTGTACCTGAATCGGACTTGTTATA
TGCAGAGCCTGATTTTAAAGGTATGAATCATATTGGTTATGATGTGATGGCGGTTGGTAATCATGAGTTTGATAACCCGT
TAGCGGTACTGGACAAACAAAGGCAATGGGCTGAGTTCCCTATGCTGGCAGCAAACATCTACAAATCAGTTGAAATCAAT
GGTGTCACTAAACAAGTGCGCTACTTTGAACCTTATAAAATTTTTGAGTTTAATGGGCTTAAGCTGGCCGTAATCGGCAT
GACAACAGAAGACACGGTTAGAATCGGTAACCCTGAATATGTCAGTGAACTGGCTTTTACCGAGCCCCAACAAGAAATTA
AAAATGTTATCGCAGAGATAGAGCAGTTGCACTCGGTTGATATCATTTTTGCCGTGACTCATATGGGGCATTATGCCAAC
GGGCTGCACGGCAGTAATGCCCCTGGTGACGTATTGATGGCAAAGTCGCTTAAGGTCGGGCAGTTGCAAGCCATTTTTGG
TGGCCATTCCCAAAACCCGGTTTGCATGGAGTCTAATAGTCACAATACCAACAATTATGCCGATTTTGCCCCAGGGGATA
AGTGTATTCCAGACCAGCAAAATGACACATGGATAATGCAAGCCCACGAATGGGGTAAGTATGTGGGCCGTGCAGACTTT
GAATTCTTCAATGGCAAATTGAATCTGGCTAAGTTTGAATTAATTCCAGTGAACCTTAAAGTTAAAAATAGCAATGGTGA
AAGGATTTTAGTGGGTGATGCAATTATACCCGATCAGGAGCTAAAAGAGTTTCTACTGCCTTTTCAATTGCGTGGACAAG
ATAAGCTTGATGAGGTTATTGGTGTCACCAAAGGAAAACTCATTGGTGATCGCGATCTAGTGCGCAGTCAACAAACCAAC
TTAGGTCGCTTAATCGCAATGGCACAGAGTAATGGAGCAGTAAAAGCTGATTTTGGTGTTATGAATTCAGGTGGGGTACG
AGCTTCTATTGAAACAGGTGAGATCACTTATCGGGACGTACTGTCGGTGCAACCCTTTGGTAATATGATCACCTTAAATA
CAATGACAGGAGCTGAAGTGAAAGCATATTTAGCTTCGGTTGCCACTATGACGAGAGGCTCTGGAGGTTATGCGCAATTT
TCCGGAATAGAGATGGTAGTTAACTGCACTGAAAAGGCTGTAGAGATCAGCAAAATTGGCGGACGTGATTTCAATATAAG
TGATAGCTACAGTTTCACCGTCCCAAGTTATAATGCGGCAGGTGGCAATGATTATCCCAAGCTGACTGAAGCCATCAATA
CTGGATTTGTCGATGCCGATATATTGTATCAATTTTTCAAGAAACAACCTCAAATTAATGCCGCTGATTTTGATTCTCGC
AAAGAGATCACTTATATGAGGAGTTCCAGCCCATTTGGATGTGATCCTGCCTCATAA

Upstream 100 bases:

>100_bases
TAAATTTTAGTTGATTTAGCAGGCAAAAGAAAAGTCGAGAGACCTCATCTCGGCTTTTTCTTATTAAGCTTAAACGCAAT
TTTTAATTCCAACTATAAAA

Downstream 100 bases:

>100_bases
CGAGATCCTTAGTGAAAGAAAATAGGTAAAGTTTCGGTATGTTCAAGACTACAGTTCTCAATTTGATTGCTCGGCAATGG
TAAAACAATAAGTTCAACTA

Product: bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 578; Mature: 578

Protein sequence:

>578_residues
MMRCTMRVNYIGSVSVIAVILLSGCGINQKSFATCAAAGDACTRFTILHTNDNHGRFWENKHGEYGMAARKTLIDSIRQE
VNAQGEHVLLFSGGDINTGVPESDLLYAEPDFKGMNHIGYDVMAVGNHEFDNPLAVLDKQRQWAEFPMLAANIYKSVEIN
GVTKQVRYFEPYKIFEFNGLKLAVIGMTTEDTVRIGNPEYVSELAFTEPQQEIKNVIAEIEQLHSVDIIFAVTHMGHYAN
GLHGSNAPGDVLMAKSLKVGQLQAIFGGHSQNPVCMESNSHNTNNYADFAPGDKCIPDQQNDTWIMQAHEWGKYVGRADF
EFFNGKLNLAKFELIPVNLKVKNSNGERILVGDAIIPDQELKEFLLPFQLRGQDKLDEVIGVTKGKLIGDRDLVRSQQTN
LGRLIAMAQSNGAVKADFGVMNSGGVRASIETGEITYRDVLSVQPFGNMITLNTMTGAEVKAYLASVATMTRGSGGYAQF
SGIEMVVNCTEKAVEISKIGGRDFNISDSYSFTVPSYNAAGGNDYPKLTEAINTGFVDADILYQFFKKQPQINAADFDSR
KEITYMRSSSPFGCDPAS

Sequences:

>Translated_578_residues
MMRCTMRVNYIGSVSVIAVILLSGCGINQKSFATCAAAGDACTRFTILHTNDNHGRFWENKHGEYGMAARKTLIDSIRQE
VNAQGEHVLLFSGGDINTGVPESDLLYAEPDFKGMNHIGYDVMAVGNHEFDNPLAVLDKQRQWAEFPMLAANIYKSVEIN
GVTKQVRYFEPYKIFEFNGLKLAVIGMTTEDTVRIGNPEYVSELAFTEPQQEIKNVIAEIEQLHSVDIIFAVTHMGHYAN
GLHGSNAPGDVLMAKSLKVGQLQAIFGGHSQNPVCMESNSHNTNNYADFAPGDKCIPDQQNDTWIMQAHEWGKYVGRADF
EFFNGKLNLAKFELIPVNLKVKNSNGERILVGDAIIPDQELKEFLLPFQLRGQDKLDEVIGVTKGKLIGDRDLVRSQQTN
LGRLIAMAQSNGAVKADFGVMNSGGVRASIETGEITYRDVLSVQPFGNMITLNTMTGAEVKAYLASVATMTRGSGGYAQF
SGIEMVVNCTEKAVEISKIGGRDFNISDSYSFTVPSYNAAGGNDYPKLTEAINTGFVDADILYQFFKKQPQINAADFDSR
KEITYMRSSSPFGCDPAS
>Mature_578_residues
MMRCTMRVNYIGSVSVIAVILLSGCGINQKSFATCAAAGDACTRFTILHTNDNHGRFWENKHGEYGMAARKTLIDSIRQE
VNAQGEHVLLFSGGDINTGVPESDLLYAEPDFKGMNHIGYDVMAVGNHEFDNPLAVLDKQRQWAEFPMLAANIYKSVEIN
GVTKQVRYFEPYKIFEFNGLKLAVIGMTTEDTVRIGNPEYVSELAFTEPQQEIKNVIAEIEQLHSVDIIFAVTHMGHYAN
GLHGSNAPGDVLMAKSLKVGQLQAIFGGHSQNPVCMESNSHNTNNYADFAPGDKCIPDQQNDTWIMQAHEWGKYVGRADF
EFFNGKLNLAKFELIPVNLKVKNSNGERILVGDAIIPDQELKEFLLPFQLRGQDKLDEVIGVTKGKLIGDRDLVRSQQTN
LGRLIAMAQSNGAVKADFGVMNSGGVRASIETGEITYRDVLSVQPFGNMITLNTMTGAEVKAYLASVATMTRGSGGYAQF
SGIEMVVNCTEKAVEISKIGGRDFNISDSYSFTVPSYNAAGGNDYPKLTEAINTGFVDADILYQFFKKQPQINAADFDSR
KEITYMRSSSPFGCDPAS

Specific function: Degradation of extracellular 5'-nucleotides for nutritional needs [H]

COG id: COG0737

COG function: function code F; 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 5'-nucleotidase family [H]

Homologues:

Organism=Homo sapiens, GI4505467, Length=556, Percent_Identity=24.2805755395683, Blast_Score=114, Evalue=4e-25,
Organism=Escherichia coli, GI1786687, Length=556, Percent_Identity=49.2805755395683, Blast_Score=552, Evalue=1e-158,
Organism=Drosophila melanogaster, GI19922446, Length=478, Percent_Identity=27.6150627615063, Blast_Score=132, Evalue=7e-31,
Organism=Drosophila melanogaster, GI24654424, Length=478, Percent_Identity=27.6150627615063, Blast_Score=132, Evalue=7e-31,
Organism=Drosophila melanogaster, GI19922444, Length=577, Percent_Identity=24.9566724436742, Blast_Score=116, Evalue=5e-26,
Organism=Drosophila melanogaster, GI28573524, Length=555, Percent_Identity=23.4234234234234, Blast_Score=107, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24641187, Length=538, Percent_Identity=22.8624535315985, Blast_Score=85, Evalue=1e-16,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008334
- InterPro:   IPR006146
- InterPro:   IPR006179
- InterPro:   IPR004843 [H]

Pfam domain/function: PF02872 5_nucleotid_C; PF00149 Metallophos [H]

EC number: =3.1.3.5 [H]

Molecular weight: Translated: 63565; Mature: 63565

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00786 5_NUCLEOTIDASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMRCTMRVNYIGSVSVIAVILLSGCGINQKSFATCAAAGDACTRFTILHTNDNHGRFWEN
CEEEEEEEEECCHHHHHHHHHHHCCCCCHHHHEHHHHCCCCEEEEEEEEECCCCCCCCCC
KHGEYGMAARKTLIDSIRQEVNAQGEHVLLFSGGDINTGVPESDLLYAEPDFKGMNHIGY
CCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCEEEECCCCCCCCCCCE
DVMAVGNHEFDNPLAVLDKQRQWAEFPMLAANIYKSVEINGVTKQVRYFEPYKIFEFNGL
EEEEECCCCCCCCHHHHCCCHHHHHCCHHHHHHHHEEEECCCCEEEEECCCEEEEEECCE
KLAVIGMTTEDTVRIGNPEYVSELAFTEPQQEIKNVIAEIEQLHSVDIIFAVTHMGHYAN
EEEEEEECCCCEEEECCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCEEEEEEECCCHHHC
GLHGSNAPGDVLMAKSLKVGQLQAIFGGHSQNPVCMESNSHNTNNYADFAPGDKCIPDQQ
CCCCCCCCCCEEEECCCCCCEEEEEECCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCC
NDTWIMQAHEWGKYVGRADFEFFNGKLNLAKFELIPVNLKVKNSNGERILVGDAIIPDQE
CCEEEEEEHHHHHHCCCCCEEEECCEEEEEEEEEEEEEEEEECCCCCEEEECCCCCCHHH
LKEFLLPFQLRGQDKLDEVIGVTKGKLIGDRDLVRSQQTNLGRLIAMAQSNGAVKADFGV
HHHHHCCEEECCCHHHHHHHCCCCCCEECCHHHHHHHHCCCEEEEEEECCCCCEEEECCE
MNSGGVRASIETGEITYRDVLSVQPFGNMITLNTMTGAEVKAYLASVATMTRGSGGYAQF
ECCCCEEEEEECCCEEHHHHEEECCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCEEEE
SGIEMVVNCTEKAVEISKIGGRDFNISDSYSFTVPSYNAAGGNDYPKLTEAINTGFVDAD
CCEEEEEECCHHHEEHHHCCCCCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHCCCCCHH
ILYQFFKKQPQINAADFDSRKEITYMRSSSPFGCDPAS
HHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCCCCCC
>Mature Secondary Structure
MMRCTMRVNYIGSVSVIAVILLSGCGINQKSFATCAAAGDACTRFTILHTNDNHGRFWEN
CEEEEEEEEECCHHHHHHHHHHHCCCCCHHHHEHHHHCCCCEEEEEEEEECCCCCCCCCC
KHGEYGMAARKTLIDSIRQEVNAQGEHVLLFSGGDINTGVPESDLLYAEPDFKGMNHIGY
CCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCEEEECCCCCCCCCCCE
DVMAVGNHEFDNPLAVLDKQRQWAEFPMLAANIYKSVEINGVTKQVRYFEPYKIFEFNGL
EEEEECCCCCCCCHHHHCCCHHHHHCCHHHHHHHHEEEECCCCEEEEECCCEEEEEECCE
KLAVIGMTTEDTVRIGNPEYVSELAFTEPQQEIKNVIAEIEQLHSVDIIFAVTHMGHYAN
EEEEEEECCCCEEEECCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCEEEEEEECCCHHHC
GLHGSNAPGDVLMAKSLKVGQLQAIFGGHSQNPVCMESNSHNTNNYADFAPGDKCIPDQQ
CCCCCCCCCCEEEECCCCCCEEEEEECCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCC
NDTWIMQAHEWGKYVGRADFEFFNGKLNLAKFELIPVNLKVKNSNGERILVGDAIIPDQE
CCEEEEEEHHHHHHCCCCCEEEECCEEEEEEEEEEEEEEEEECCCCCEEEECCCCCCHHH
LKEFLLPFQLRGQDKLDEVIGVTKGKLIGDRDLVRSQQTNLGRLIAMAQSNGAVKADFGV
HHHHHCCEEECCCHHHHHHHCCCCCCEECCHHHHHHHHCCCEEEEEEECCCCCEEEECCE
MNSGGVRASIETGEITYRDVLSVQPFGNMITLNTMTGAEVKAYLASVATMTRGSGGYAQF
ECCCCEEEEEECCCEEHHHHEEECCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCEEEE
SGIEMVVNCTEKAVEISKIGGRDFNISDSYSFTVPSYNAAGGNDYPKLTEAINTGFVDAD
CCEEEEEECCHHHEEHHHCCCCCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHCCCCCHH
ILYQFFKKQPQINAADFDSRKEITYMRSSSPFGCDPAS
HHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA