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The map label for this gene is umuC [H]

Identifier: 167624107

GI number: 167624107

Start: 2641539

End: 2642792

Strand: Reverse

Name: umuC [H]

Synonym: Shal_2183

Alternate gene names: 167624107

Gene position: 2642792-2641539 (Counterclockwise)

Preceding gene: 167624108

Following gene: 167624106

Centisome position: 50.56

GC content: 43.62

Gene sequence:

>1254_bases
ATGTATGCGCTTGTCGATGCCAATTCTTTCTATTGCAGTGCTGAACAGGTTTTTAGGCCTGAATGGCGTAACCGCCCTAT
TATCGTGTTGAGTAATAATGATGGTTGTATTGTTGCGGCCAACAGATTGGCGAAAGAAGCGGGAATTAAAAAGTTCGGTC
CTTACTTTGAAGCCAAAAGGCTGTGTGAGCAAAAAGGTATTATCGCGTTGTCTTCAAACTATGAGCTTTACGGCTCTTTA
TCTGCATCTATGATGGAGGTGATTGGCCGCTTTGCCCCACAGCAGCATATCTACAGCATTGATGAGTCTTTTTTATCGTT
TAAGCACTGTTACCCCGCTATACCATGCCTAACTGAGCACGCATTAAAACTTAGGCGCGCCGTTTGGAAAGAAACAAGGT
TGCCTGTTTGTGTTGGAATTGGTGAGACACTGACCTTAGCCAAAGTCGCTAATCATGCTGCAAAAAAACTCCCTGGTTAT
AATGGCGTTTGTGCCATTACTAACAATGAGCAACGTTCAGCAATTTTAAAAACGATGAAAACCGATGATGTCTGGGGCGT
CGGTGGCCGCATAGCCAAAAGGCTCGCAGCAATGAATATTCACAATGCCTATGCGTTGTCGCAAATGAAAGCCGGCATCG
CCAGAAAGCAATTCAGTATTGAACTTGAACGAACTGTAAGAGAACTAAACGGTGAAGTGTGCAAGACTTGGGATGAAGCA
AGAGCTGACAAGAAACAGATATTTTCAACTCGCAGTGTTGGCAACAGAGTGACTGATTTACCTTCATTATGCCAAGCATT
AAGTAAACACGCTTCAACTGCAGCCGCTAAAGCAAGAATTCAAGGTTCACTGTGTAAAAGCATGCTGGTGTTTGCGTCAA
ACTCACCTTTTGATGAGCATCCAAGCGGGTTTAAGTATCTGCACCATTTTGCATACCCAACAAATGACACTTGCGAACTC
ATTGAAGCTGCAACTCAGGCTGCAATGGTTAGATTTAATCCCGCTATTCGTTATTACAAAATCGGCGTTGGACTCATTAA
CTTGTGTAGTGAAGCCAATCTGCAAGGAGATTTATTTGAAGGCGGTAGAAATCCAAGTAAAATGCTGGTCTTGGATAAAA
TCAACGCCAAGTACGGTACTGACACGTTGTTTCTCGCTGCCCAAGGTATATCGCAGAAATGGGGAATGCGCAGAGACATG
CTGACTCCGCAATACACTACACGCTGGAAAGACATTCCTTTGATTAAATGCTAA

Upstream 100 bases:

>100_bases
GCACGCCTATTCTCGAACACGATACATTTAGTGTAGAAGGCGTCGTTATACGCTCAATACGCTGTAATCGTAAAAGCCCT
ATTCTTGAGAATGATTAATC

Downstream 100 bases:

>100_bases
TCAATGTAGGTTCTGATTCATTAAGTTTAATTAAATCATGCTTATTTTTACTATAAAGCCTATGATAGTTAAGGCAAAAT
CAGCCAAACTATTTTAATCA

Product: DNA-directed DNA polymerase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 417; Mature: 417

Protein sequence:

>417_residues
MYALVDANSFYCSAEQVFRPEWRNRPIIVLSNNDGCIVAANRLAKEAGIKKFGPYFEAKRLCEQKGIIALSSNYELYGSL
SASMMEVIGRFAPQQHIYSIDESFLSFKHCYPAIPCLTEHALKLRRAVWKETRLPVCVGIGETLTLAKVANHAAKKLPGY
NGVCAITNNEQRSAILKTMKTDDVWGVGGRIAKRLAAMNIHNAYALSQMKAGIARKQFSIELERTVRELNGEVCKTWDEA
RADKKQIFSTRSVGNRVTDLPSLCQALSKHASTAAAKARIQGSLCKSMLVFASNSPFDEHPSGFKYLHHFAYPTNDTCEL
IEAATQAAMVRFNPAIRYYKIGVGLINLCSEANLQGDLFEGGRNPSKMLVLDKINAKYGTDTLFLAAQGISQKWGMRRDM
LTPQYTTRWKDIPLIKC

Sequences:

>Translated_417_residues
MYALVDANSFYCSAEQVFRPEWRNRPIIVLSNNDGCIVAANRLAKEAGIKKFGPYFEAKRLCEQKGIIALSSNYELYGSL
SASMMEVIGRFAPQQHIYSIDESFLSFKHCYPAIPCLTEHALKLRRAVWKETRLPVCVGIGETLTLAKVANHAAKKLPGY
NGVCAITNNEQRSAILKTMKTDDVWGVGGRIAKRLAAMNIHNAYALSQMKAGIARKQFSIELERTVRELNGEVCKTWDEA
RADKKQIFSTRSVGNRVTDLPSLCQALSKHASTAAAKARIQGSLCKSMLVFASNSPFDEHPSGFKYLHHFAYPTNDTCEL
IEAATQAAMVRFNPAIRYYKIGVGLINLCSEANLQGDLFEGGRNPSKMLVLDKINAKYGTDTLFLAAQGISQKWGMRRDM
LTPQYTTRWKDIPLIKC
>Mature_417_residues
MYALVDANSFYCSAEQVFRPEWRNRPIIVLSNNDGCIVAANRLAKEAGIKKFGPYFEAKRLCEQKGIIALSSNYELYGSL
SASMMEVIGRFAPQQHIYSIDESFLSFKHCYPAIPCLTEHALKLRRAVWKETRLPVCVGIGETLTLAKVANHAAKKLPGY
NGVCAITNNEQRSAILKTMKTDDVWGVGGRIAKRLAAMNIHNAYALSQMKAGIARKQFSIELERTVRELNGEVCKTWDEA
RADKKQIFSTRSVGNRVTDLPSLCQALSKHASTAAAKARIQGSLCKSMLVFASNSPFDEHPSGFKYLHHFAYPTNDTCEL
IEAATQAAMVRFNPAIRYYKIGVGLINLCSEANLQGDLFEGGRNPSKMLVLDKINAKYGTDTLFLAAQGISQKWGMRRDM
LTPQYTTRWKDIPLIKC

Specific function: Involved in UV protection and mutation. Essential for induced (or SOS) mutagenesis. May modify the DNA replication machinery to allow bypass synthesis across a damaged template [H]

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Escherichia coli, GI1787432, Length=426, Percent_Identity=41.0798122065728, Blast_Score=310, Evalue=1e-85,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: NA

Molecular weight: Translated: 46496; Mature: 46496

Theoretical pI: Translated: 9.57; Mature: 9.57

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYALVDANSFYCSAEQVFRPEWRNRPIIVLSNNDGCIVAANRLAKEAGIKKFGPYFEAKR
CEEEEECCCCEECHHHHHCCHHCCCCEEEEECCCCEEEEHHHHHHHCCCHHHCCHHHHHH
LCEQKGIIALSSNYELYGSLSASMMEVIGRFAPQQHIYSIDESFLSFKHCYPAIPCLTEH
HHHHCCEEEEECCCEEEECHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHH
ALKLRRAVWKETRLPVCVGIGETLTLAKVANHAAKKLPGYNGVCAITNNEQRSAILKTMK
HHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHC
TDDVWGVGGRIAKRLAAMNIHNAYALSQMKAGIARKQFSIELERTVRELNGEVCKTWDEA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCHHHH
RADKKQIFSTRSVGNRVTDLPSLCQALSKHASTAAAKARIQGSLCKSMLVFASNSPFDEH
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
PSGFKYLHHFAYPTNDTCELIEAATQAAMVRFNPAIRYYKIGVGLINLCSEANLQGDLFE
CCHHHHHHHHCCCCCCHHHHHHHHHHHHHHEECCCEEEEEECHHHHHHHHCCCCCCCHHC
GGRNPSKMLVLDKINAKYGTDTLFLAAQGISQKWGMRRDMLTPQYTTRWKDIPLIKC
CCCCCCEEEEEEECCCCCCCCEEEEEECCCHHHCCCHHHCCCCCHHCCCCCCCCCCC
>Mature Secondary Structure
MYALVDANSFYCSAEQVFRPEWRNRPIIVLSNNDGCIVAANRLAKEAGIKKFGPYFEAKR
CEEEEECCCCEECHHHHHCCHHCCCCEEEEECCCCEEEEHHHHHHHCCCHHHCCHHHHHH
LCEQKGIIALSSNYELYGSLSASMMEVIGRFAPQQHIYSIDESFLSFKHCYPAIPCLTEH
HHHHCCEEEEECCCEEEECHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHH
ALKLRRAVWKETRLPVCVGIGETLTLAKVANHAAKKLPGYNGVCAITNNEQRSAILKTMK
HHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHC
TDDVWGVGGRIAKRLAAMNIHNAYALSQMKAGIARKQFSIELERTVRELNGEVCKTWDEA
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCHHHH
RADKKQIFSTRSVGNRVTDLPSLCQALSKHASTAAAKARIQGSLCKSMLVFASNSPFDEH
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
PSGFKYLHHFAYPTNDTCELIEAATQAAMVRFNPAIRYYKIGVGLINLCSEANLQGDLFE
CCHHHHHHHHCCCCCCHHHHHHHHHHHHHHEECCCEEEEEECHHHHHHHHCCCCCCCHHC
GGRNPSKMLVLDKINAKYGTDTLFLAAQGISQKWGMRRDMLTPQYTTRWKDIPLIKC
CCCCCCEEEEEEECCCCCCCCEEEEEECCCHHHCCCHHHCCCCCHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2989817; 2989816; 8905232; 9278503; 1320188 [H]