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The map label for this gene is emrK [H]

Identifier: 167624088

GI number: 167624088

Start: 2613614

End: 2614657

Strand: Reverse

Name: emrK [H]

Synonym: Shal_2164

Alternate gene names: 167624088

Gene position: 2614657-2613614 (Counterclockwise)

Preceding gene: 167624089

Following gene: 167624087

Centisome position: 50.02

GC content: 45.88

Gene sequence:

>1044_bases
ATGAGCGAAAATTCAACACAAGCACAATCCCATCTAATACGTAACCTTATTATCGCAACCATAGCGATTGCCGTCTTAGC
CACCCTCAGTTATTTCTATATTCAGCACCAAAAGAACTATCCCAGTACCGATGATGCTTATATACACGCTAATATTATCT
ACATTGCTCCACAAGTCAGCGGCAAGGTGAGCAGTGTCAATGCATCCGATTATCAAAAGGTTAGTCAAGGTGATTTGTTA
GTACAGATAGACTCTGCCCCTTTTCAAGCAAAACTCGATGAAGCCCGTGCTGCCTATGAGATGGCGCTACAAAACAATGC
AGCAACAGATGACGCCATACTCGCGGCCAGTGCCAATGTTAAAAGTGCAGTGGCTCAATTATCCGATGCCCAAGTAACTT
ATAAGCGTACTAAAGACTTAGTTGATAAAGAATTGCTGCCTGAACAGCAGCTTGACGATACACGAGCCAAGCTTTCTGCA
GCCGAGCAGAGTGTGATAGCCGCGCGCGCAACCATGGCTCAGTTAATTAAATCTCAAGGTGCGCATGGTAATGCTGCACC
TGAAGTAAAAAAGGCAGCAGCTGCGCTCAGTCAGGCCAGTCTATCGCTTTCTTACACTAATATTTTCGCTCCTAAAGATG
GCCATTTAGGCAAGTTAAGTGCCCATGCCGGTAGTGTTGTATCCCCGGGACAAGCTATTGTGCCTCTCGTTGTTGATAAC
ACTTATTGGGTTCAAGCAAACTTTAAAGAAACACAACTAGAGCGACTTACCGCCGGCCAAACTGCAACAATCACCCTAGA
CCTTTATCCTAAGGTGGATTACCACGGCACCATTGAGGCGATTTCACCAGCAAGTGGTGCATCTTTTACCCTGTTGCCGC
CTGAGAATGCAACCGGTAACTGGGTAAAAGTTCCACAACGTTTCCCTGTATTAGTTCGCCTAACCAATGAAAGTGAGCAC
CCTGACTTTCCTCTACGTGTTGGCGCAAGTGCTAACGTAAGCATAGACACGGTTAATAGCCCATCTAAGCAACAAGAGCA
GTAA

Upstream 100 bases:

>100_bases
ACTAGGTCTAGTATTTATTGAAACGAATGAGCATCTTGCAGTGCTATGAGTCTTCAAACCCTTCTCGACTAATTGTCGAA
TAACCAACCTGGTTAAAATT

Downstream 100 bases:

>100_bases
CATGAGCGATACTTCAGAGACGATGCCTGATACTGATGACAGTCAGGTAATGAGTGAAAGCAGCCGTAAACTCGTCACTT
TAGCGGTAATGCTATCGGCC

Product: secretion protein HlyD family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 347; Mature: 346

Protein sequence:

>347_residues
MSENSTQAQSHLIRNLIIATIAIAVLATLSYFYIQHQKNYPSTDDAYIHANIIYIAPQVSGKVSSVNASDYQKVSQGDLL
VQIDSAPFQAKLDEARAAYEMALQNNAATDDAILAASANVKSAVAQLSDAQVTYKRTKDLVDKELLPEQQLDDTRAKLSA
AEQSVIAARATMAQLIKSQGAHGNAAPEVKKAAAALSQASLSLSYTNIFAPKDGHLGKLSAHAGSVVSPGQAIVPLVVDN
TYWVQANFKETQLERLTAGQTATITLDLYPKVDYHGTIEAISPASGASFTLLPPENATGNWVKVPQRFPVLVRLTNESEH
PDFPLRVGASANVSIDTVNSPSKQQEQ

Sequences:

>Translated_347_residues
MSENSTQAQSHLIRNLIIATIAIAVLATLSYFYIQHQKNYPSTDDAYIHANIIYIAPQVSGKVSSVNASDYQKVSQGDLL
VQIDSAPFQAKLDEARAAYEMALQNNAATDDAILAASANVKSAVAQLSDAQVTYKRTKDLVDKELLPEQQLDDTRAKLSA
AEQSVIAARATMAQLIKSQGAHGNAAPEVKKAAAALSQASLSLSYTNIFAPKDGHLGKLSAHAGSVVSPGQAIVPLVVDN
TYWVQANFKETQLERLTAGQTATITLDLYPKVDYHGTIEAISPASGASFTLLPPENATGNWVKVPQRFPVLVRLTNESEH
PDFPLRVGASANVSIDTVNSPSKQQEQ
>Mature_346_residues
SENSTQAQSHLIRNLIIATIAIAVLATLSYFYIQHQKNYPSTDDAYIHANIIYIAPQVSGKVSSVNASDYQKVSQGDLLV
QIDSAPFQAKLDEARAAYEMALQNNAATDDAILAASANVKSAVAQLSDAQVTYKRTKDLVDKELLPEQQLDDTRAKLSAA
EQSVIAARATMAQLIKSQGAHGNAAPEVKKAAAALSQASLSLSYTNIFAPKDGHLGKLSAHAGSVVSPGQAIVPLVVDNT
YWVQANFKETQLERLTAGQTATITLDLYPKVDYHGTIEAISPASGASFTLLPPENATGNWVKVPQRFPVLVRLTNESEHP
DFPLRVGASANVSIDTVNSPSKQQEQ

Specific function: Unknown

COG id: COG1566

COG function: function code V; Multidrug resistance efflux pump

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1788711, Length=334, Percent_Identity=35.0299401197605, Blast_Score=168, Evalue=4e-43,
Organism=Escherichia coli, GI1789041, Length=321, Percent_Identity=32.7102803738318, Blast_Score=165, Evalue=4e-42,
Organism=Escherichia coli, GI1790519, Length=325, Percent_Identity=30.4615384615385, Blast_Score=118, Evalue=5e-28,
Organism=Escherichia coli, GI87081951, Length=324, Percent_Identity=27.1604938271605, Blast_Score=92, Evalue=7e-20,
Organism=Escherichia coli, GI1789637, Length=308, Percent_Identity=27.9220779220779, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1790024, Length=278, Percent_Identity=24.4604316546763, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1789929, Length=214, Percent_Identity=28.9719626168224, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1790012, Length=277, Percent_Identity=25.6317689530686, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1787013, Length=272, Percent_Identity=24.2647058823529, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005694
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 37195; Mature: 37064

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSENSTQAQSHLIRNLIIATIAIAVLATLSYFYIQHQKNYPSTDDAYIHANIIYIAPQVS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCEEEEEEEEEECCCC
GKVSSVNASDYQKVSQGDLLVQIDSAPFQAKLDEARAAYEMALQNNAATDDAILAASANV
CCEEECCCHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCH
KSAVAQLSDAQVTYKRTKDLVDKELLPEQQLDDTRAKLSAAEQSVIAARATMAQLIKSQG
HHHHHHHCCCEEHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
AHGNAAPEVKKAAAALSQASLSLSYTNIFAPKDGHLGKLSAHAGSVVSPGQAIVPLVVDN
CCCCCCHHHHHHHHHHHHHHEEEEEEEEECCCCCCCEEEECCCCCCCCCCCEEEEEEECC
TYWVQANFKETQLERLTAGQTATITLDLYPKVDYHGTIEAISPASGASFTLLPPENATGN
EEEEEECCCHHHHHHHHCCCEEEEEEEECCCCCCCCEEEEECCCCCCEEEEECCCCCCCC
WVKVPQRFPVLVRLTNESEHPDFPLRVGASANVSIDTVNSPSKQQEQ
EEECCCCCCEEEEEECCCCCCCCCEEECCCCCEEEEECCCCCHHCCC
>Mature Secondary Structure 
SENSTQAQSHLIRNLIIATIAIAVLATLSYFYIQHQKNYPSTDDAYIHANIIYIAPQVS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCEEEEEEEEEECCCC
GKVSSVNASDYQKVSQGDLLVQIDSAPFQAKLDEARAAYEMALQNNAATDDAILAASANV
CCEEECCCHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCH
KSAVAQLSDAQVTYKRTKDLVDKELLPEQQLDDTRAKLSAAEQSVIAARATMAQLIKSQG
HHHHHHHCCCEEHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
AHGNAAPEVKKAAAALSQASLSLSYTNIFAPKDGHLGKLSAHAGSVVSPGQAIVPLVVDN
CCCCCCHHHHHHHHHHHHHHEEEEEEEEECCCCCCCEEEECCCCCCCCCCCEEEEEEECC
TYWVQANFKETQLERLTAGQTATITLDLYPKVDYHGTIEAISPASGASFTLLPPENATGN
EEEEEECCCHHHHHHHHCCCEEEEEEEECCCCCCCCEEEEECCCCCCEEEEECCCCCCCC
WVKVPQRFPVLVRLTNESEHPDFPLRVGASANVSIDTVNSPSKQQEQ
EEECCCCCCEEEEEECCCCCCCCCEEECCCCCEEEEECCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]