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The map label for this gene is caiD [C]

Identifier: 167624053

GI number: 167624053

Start: 2564058

End: 2564843

Strand: Direct

Name: caiD [C]

Synonym: Shal_2129

Alternate gene names: 167624053

Gene position: 2564058-2564843 (Clockwise)

Preceding gene: 167624052

Following gene: 167624054

Centisome position: 49.05

GC content: 45.67

Gene sequence:

>786_bases
ATGGTCAAAGCTACTGTTAATCCTATTTCGCAACCTAAGCCTGCATTTATTACAGAATTAAATGATGGCGTTGCAGAATT
AATTATAAATAAACCCCCAGTCAATGCATTAGATAGTCTTGAATGGTTCGCATTAGCCAATGAGGTTGAAAGACTCAATG
CTGACTTGGCCGTTAGAGTGATTGTCATTCGTGCTGAAGGGCGAGGCTTTTGTGCAGGGGTTGATATTAAAGAGTTGGAT
CAATATCCAGAACGTATCGTTGCGGTTAATGGCGGAAATTATGCAACCTTTAAAGCCATTCATCGTGCGACAGTACCTGT
GATTGTCGCTGTTCATGGATTTGTCCTCGGTGGTGGAATTGGGATCACTGGTGCTGCAGATATTGTCGTTGCATCAGATT
GTGCCACGTTTGCATTACCCGAAGTCGACCGCGGTGCAATGGGTGGCGGAGCCCATTTACAAAGATTGTTTCCGGTTCAA
AAAGTGCGCTACTTGTTTTTTACTGGTGATGCGATCAGCGCACCAGATGCCGAGCGATATGGCTTTATTGAACGTATTGT
TTCCAAGTCAGAGCTGCGTAGTACTGCATTAGAAATTGCGGCCAAGATTGCGGCGAAAAGTCCTGAAATGATCCGAATGG
CTAAAGAAGCGTTAAACGGCATCGAAGACGGCAATTTAGAAGATAAGTACCGTTGGGAGCAAGGGTTTACGCTACAGGCC
TATACCTCTCCAGACTCAGCCGAAACCCGCCGCGCGTTTGTAGAAAAGCGTGAAGCGAGCTTCTAA

Upstream 100 bases:

>100_bases
TAAACCAAGCTAAGCAATGTTTAACACAACTGCAAACTCGAACATTAATGACTGAGTCACTAGACAATAAAAAAAACCCT
AAAAAAGAGGCTAGCTAATT

Downstream 100 bases:

>100_bases
ATTTTAATCCTTTACCATTCGAGGCAGCTTATGGATTTAACATATACAAAAAAACAACAAGCTTTTCGGTTAGAAGTACG
CCAATGGTTAGCGGATAACT

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: 3-hydroxypropionyl-CoA dehydratase [H]

Number of amino acids: Translated: 261; Mature: 261

Protein sequence:

>261_residues
MVKATVNPISQPKPAFITELNDGVAELIINKPPVNALDSLEWFALANEVERLNADLAVRVIVIRAEGRGFCAGVDIKELD
QYPERIVAVNGGNYATFKAIHRATVPVIVAVHGFVLGGGIGITGAADIVVASDCATFALPEVDRGAMGGGAHLQRLFPVQ
KVRYLFFTGDAISAPDAERYGFIERIVSKSELRSTALEIAAKIAAKSPEMIRMAKEALNGIEDGNLEDKYRWEQGFTLQA
YTSPDSAETRRAFVEKREASF

Sequences:

>Translated_261_residues
MVKATVNPISQPKPAFITELNDGVAELIINKPPVNALDSLEWFALANEVERLNADLAVRVIVIRAEGRGFCAGVDIKELD
QYPERIVAVNGGNYATFKAIHRATVPVIVAVHGFVLGGGIGITGAADIVVASDCATFALPEVDRGAMGGGAHLQRLFPVQ
KVRYLFFTGDAISAPDAERYGFIERIVSKSELRSTALEIAAKIAAKSPEMIRMAKEALNGIEDGNLEDKYRWEQGFTLQA
YTSPDSAETRRAFVEKREASF
>Mature_261_residues
MVKATVNPISQPKPAFITELNDGVAELIINKPPVNALDSLEWFALANEVERLNADLAVRVIVIRAEGRGFCAGVDIKELD
QYPERIVAVNGGNYATFKAIHRATVPVIVAVHGFVLGGGIGITGAADIVVASDCATFALPEVDRGAMGGGAHLQRLFPVQ
KVRYLFFTGDAISAPDAERYGFIERIVSKSELRSTALEIAAKIAAKSPEMIRMAKEALNGIEDGNLEDKYRWEQGFTLQA
YTSPDSAETRRAFVEKREASF

Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the reversible dehydration of 3-hydroxypropionyl-CoA to form acryloyl- CoA, and the reversible dehydration of (S)-3-hydroxybutyryl-CoA to form crot

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=251, Percent_Identity=31.0756972111554, Blast_Score=106, Evalue=2e-23,
Organism=Homo sapiens, GI31542718, Length=254, Percent_Identity=28.740157480315, Blast_Score=92, Evalue=3e-19,
Organism=Homo sapiens, GI70995211, Length=263, Percent_Identity=26.9961977186312, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI4502327, Length=256, Percent_Identity=29.296875, Blast_Score=65, Evalue=5e-11,
Organism=Escherichia coli, GI221142681, Length=246, Percent_Identity=31.3008130081301, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1787659, Length=245, Percent_Identity=32.6530612244898, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI87082183, Length=235, Percent_Identity=28.5106382978723, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1788597, Length=257, Percent_Identity=25.6809338521401, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1787660, Length=255, Percent_Identity=26.6666666666667, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1790281, Length=186, Percent_Identity=27.4193548387097, Blast_Score=65, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17554946, Length=239, Percent_Identity=31.7991631799163, Blast_Score=115, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI17536985, Length=257, Percent_Identity=28.7937743190661, Blast_Score=101, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI25145438, Length=240, Percent_Identity=28.75, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17534483, Length=258, Percent_Identity=25.5813953488372, Blast_Score=95, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17540714, Length=222, Percent_Identity=30.1801801801802, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17540306, Length=274, Percent_Identity=26.6423357664234, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17560910, Length=210, Percent_Identity=25.7142857142857, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI20129971, Length=245, Percent_Identity=30.2040816326531, Blast_Score=114, Evalue=7e-26,
Organism=Drosophila melanogaster, GI24653477, Length=245, Percent_Identity=30.2040816326531, Blast_Score=114, Evalue=7e-26,
Organism=Drosophila melanogaster, GI19920382, Length=242, Percent_Identity=29.7520661157025, Blast_Score=84, Evalue=7e-17,
Organism=Drosophila melanogaster, GI24653139, Length=249, Percent_Identity=28.9156626506024, Blast_Score=80, Evalue=9e-16,
Organism=Drosophila melanogaster, GI19922422, Length=249, Percent_Identity=25.3012048192771, Blast_Score=78, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.116 [H]

Molecular weight: Translated: 28309; Mature: 28309

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKATVNPISQPKPAFITELNDGVAELIINKPPVNALDSLEWFALANEVERLNADLAVRV
CCCCCCCCCCCCCCHHHHHHCCCHHHHEECCCCCCHHHHHHHHHHHHHHHHHCCCEEEEE
IVIRAEGRGFCAGVDIKELDQYPERIVAVNGGNYATFKAIHRATVPVIVAVHGFVLGGGI
EEEEECCCCEEECCCHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
GITGAADIVVASDCATFALPEVDRGAMGGGAHLQRLFPVQKVRYLFFTGDAISAPDAERY
CCCCCCEEEEECCCHHHCCCCCCCCCCCCCHHHHHHHHHHHEEEEEEECCCCCCCCHHHH
GFIERIVSKSELRSTALEIAAKIAAKSPEMIRMAKEALNGIEDGNLEDKYRWEQGFTLQA
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCEECCCCCEEEE
YTSPDSAETRRAFVEKREASF
ECCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVKATVNPISQPKPAFITELNDGVAELIINKPPVNALDSLEWFALANEVERLNADLAVRV
CCCCCCCCCCCCCCHHHHHHCCCHHHHEECCCCCCHHHHHHHHHHHHHHHHHCCCEEEEE
IVIRAEGRGFCAGVDIKELDQYPERIVAVNGGNYATFKAIHRATVPVIVAVHGFVLGGGI
EEEEECCCCEEECCCHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
GITGAADIVVASDCATFALPEVDRGAMGGGAHLQRLFPVQKVRYLFFTGDAISAPDAERY
CCCCCCEEEEECCCHHHCCCCCCCCCCCCCHHHHHHHHHHHEEEEEEECCCCCCCCHHHH
GFIERIVSKSELRSTALEIAAKIAAKSPEMIRMAKEALNGIEDGNLEDKYRWEQGFTLQA
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCEECCCCCEEEE
YTSPDSAETRRAFVEKREASF
ECCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA