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The map label for this gene is atoD [C]

Identifier: 167624049

GI number: 167624049

Start: 2560168

End: 2561043

Strand: Direct

Name: atoD [C]

Synonym: Shal_2125

Alternate gene names: 167624049

Gene position: 2560168-2561043 (Clockwise)

Preceding gene: 167624048

Following gene: 167624050

Centisome position: 48.98

GC content: 46.0

Gene sequence:

>876_bases
ATGAACAAATTACAAACGGTAAAGCAAATGGTCGCCCAACTCGAAGACGGGATGACTATTGGCATTGGCGGTTGGGGGCC
TAGGCGCAAGCCTATGGCACTTATTCGCGAGATCCTCCGCTCTGATTTAAAAGATCTTACCATTGTTGCATATGGTGGAG
CCGACGTTGGCATGCTTTGCGCTGCAAACAAAGTAAAGAAAGTGATCTTTGCGTTTGTCTCACTGGACTTTATTCCCCTA
GAACCCTTTTTTAGAAAAGCTCGTCAAAATGGTGACATCGACATCATGGAAATTGATGAGGGAATGATGTTGCTAGGCTT
ACGTGCTGCGGCATGGGGTTGCCCGTTTATACCAACTCAAGTCGGCTTAGGTACTGATGTAGTTAAGGTCAATCCAGACT
TAAAAGTCATTGATAGTCCCTATGACGATAAAGAGTGGGTAGCCATGCCTGCATTGAAGCTCGATGCGGCACTGATCCAT
GTCGATCGAGCCGATGTTCGCGGTGTGTGTCAAATCACTGGACCGGATCACTATATGGATGATTGGTTTGTTAGAGCGGC
TAAAAAATCATTAGTGACCTGCGATGAACTTGTGGGGTCTGAGGTATTTAACGACCCTAATGCAGCACGTTGTGTGTTTT
GGGAACGCAGCCTAACGACCGCCGTTGCCCATGTCCCCGCTGGTGCTCATCCAACCTCTTGCGCGCCTTTTTACGGTTTT
GATACCGCGCACTTTAAAGAATACAACGCTTGTGCGCGTGACGGTGGCTTTGAACTGTATTTCGATAAATATGTAAAAAA
TAAGTGTGAAACTGATTATCAAGAGTTAGTCGGCGGGATAGATACAATAAAACGATTAGCATTACCGGTTTACTAA

Upstream 100 bases:

>100_bases
GCAGGTTGATTGGCAGGATCATTGTGCCTTTGAGTTTACTCGAGTGAGCATTTGGGGCCACGACTTTTCAGTCGGACAAA
ATCAACAAGGAGCTGAGTAG

Downstream 100 bases:

>100_bases
ATATATCTACGACAGCAGCGTCTTTAATACATTGCGAGGCGGTCAAATTTTGCAGCAAGGAAAAGGATAACAAGATGACT
ATAGCGAAAGAGTACAGCTT

Product: coenzyme A transferase

Products: Acetate; Butanoyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 291; Mature: 291

Protein sequence:

>291_residues
MNKLQTVKQMVAQLEDGMTIGIGGWGPRRKPMALIREILRSDLKDLTIVAYGGADVGMLCAANKVKKVIFAFVSLDFIPL
EPFFRKARQNGDIDIMEIDEGMMLLGLRAAAWGCPFIPTQVGLGTDVVKVNPDLKVIDSPYDDKEWVAMPALKLDAALIH
VDRADVRGVCQITGPDHYMDDWFVRAAKKSLVTCDELVGSEVFNDPNAARCVFWERSLTTAVAHVPAGAHPTSCAPFYGF
DTAHFKEYNACARDGGFELYFDKYVKNKCETDYQELVGGIDTIKRLALPVY

Sequences:

>Translated_291_residues
MNKLQTVKQMVAQLEDGMTIGIGGWGPRRKPMALIREILRSDLKDLTIVAYGGADVGMLCAANKVKKVIFAFVSLDFIPL
EPFFRKARQNGDIDIMEIDEGMMLLGLRAAAWGCPFIPTQVGLGTDVVKVNPDLKVIDSPYDDKEWVAMPALKLDAALIH
VDRADVRGVCQITGPDHYMDDWFVRAAKKSLVTCDELVGSEVFNDPNAARCVFWERSLTTAVAHVPAGAHPTSCAPFYGF
DTAHFKEYNACARDGGFELYFDKYVKNKCETDYQELVGGIDTIKRLALPVY
>Mature_291_residues
MNKLQTVKQMVAQLEDGMTIGIGGWGPRRKPMALIREILRSDLKDLTIVAYGGADVGMLCAANKVKKVIFAFVSLDFIPL
EPFFRKARQNGDIDIMEIDEGMMLLGLRAAAWGCPFIPTQVGLGTDVVKVNPDLKVIDSPYDDKEWVAMPALKLDAALIH
VDRADVRGVCQITGPDHYMDDWFVRAAKKSLVTCDELVGSEVFNDPNAARCVFWERSLTTAVAHVPAGAHPTSCAPFYGF
DTAHFKEYNACARDGGFELYFDKYVKNKCETDYQELVGGIDTIKRLALPVY

Specific function: Probable subunit of a CoA-transferase composed of Rv3551 and Rv3552 [H]

COG id: COG1788

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit A family [H]

Homologues:

Organism=Escherichia coli, GI1788551, Length=201, Percent_Identity=27.8606965174129, Blast_Score=68, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004165 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: 2.8.3.8 [C]

Molecular weight: Translated: 32262; Mature: 32262

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKLQTVKQMVAQLEDGMTIGIGGWGPRRKPMALIREILRSDLKDLTIVAYGGADVGMLC
CCHHHHHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCHHHHH
AANKVKKVIFAFVSLDFIPLEPFFRKARQNGDIDIMEIDEGMMLLGLRAAAWGCPFIPTQ
HHHHHHHHHHHHHHCCCEECCHHHHHHHCCCCEEEEEECCCEEEEEHHHHHCCCCCCCCC
VGLGTDVVKVNPDLKVIDSPYDDKEWVAMPALKLDAALIHVDRADVRGVCQITGPDHYMD
CCCCCCEEEECCCCEEECCCCCCCCEEECCHHHHCEEEEEECCCCCCEEEEECCCCCHHH
DWFVRAAKKSLVTCDELVGSEVFNDPNAARCVFWERSLTTAVAHVPAGAHPTSCAPFYGF
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHCCCCCCCCCCCCCCCC
DTAHFKEYNACARDGGFELYFDKYVKNKCETDYQELVGGIDTIKRLALPVY
CHHHHHHHHHHHCCCCEEEEHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNKLQTVKQMVAQLEDGMTIGIGGWGPRRKPMALIREILRSDLKDLTIVAYGGADVGMLC
CCHHHHHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCHHHHH
AANKVKKVIFAFVSLDFIPLEPFFRKARQNGDIDIMEIDEGMMLLGLRAAAWGCPFIPTQ
HHHHHHHHHHHHHHCCCEECCHHHHHHHCCCCEEEEEECCCEEEEEHHHHHCCCCCCCCC
VGLGTDVVKVNPDLKVIDSPYDDKEWVAMPALKLDAALIHVDRADVRGVCQITGPDHYMD
CCCCCCEEEECCCCEEECCCCCCCCEEECCHHHHCEEEEEECCCCCCEEEEECCCCCHHH
DWFVRAAKKSLVTCDELVGSEVFNDPNAARCVFWERSLTTAVAHVPAGAHPTSCAPFYGF
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHCCCCCCCCCCCCCCCC
DTAHFKEYNACARDGGFELYFDKYVKNKCETDYQELVGGIDTIKRLALPVY
CHHHHHHHHHHHCCCCEEEEHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Acetyl-CoA; Butyrate [C]

Specific reaction: Acetyl-CoA + Butyrate (n-C4:0) --> Acetate + Butanoyl-CoA [C]

General reaction: Coenzyme A transfer [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]