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The map label for this gene is fadE12 [H]

Identifier: 167624040

GI number: 167624040

Start: 2548678

End: 2549883

Strand: Direct

Name: fadE12 [H]

Synonym: Shal_2116

Alternate gene names: 167624040

Gene position: 2548678-2549883 (Clockwise)

Preceding gene: 167624039

Following gene: 167624043

Centisome position: 48.76

GC content: 42.12

Gene sequence:

>1206_bases
ATGAAGCTAATCTATAACGAAGATGAACGTATGTTGGCCGACATAGCCACAGAATTTTTAGAGTCTAAAAGCCCTGTTGC
CGCTAAACGTGCCCTACGAGATCAAAATAGTGATTTGTGTTTTGATCCTCACATTTGGCAAGAAATGGCACAGTTGGGCT
GGAGTGGGATAAGTTTTGCAGAGACGTTTGGTGGCCATGGCTTTAGCCATAAAGGCCTAGCGGCTATCTTTGAAGCCATC
GGCAATAACTTAACTCACTCGCCAATGCTGTCATCAGTGGTCATTTGTGGTGGTATTTTGCAACAACTGGCTAAAACTAA
TGATTTATCTGAGCAGCATATTAGTTGGCTTGAACAAATTATTAGTGGAGATAAGCGGATCGCCTTAGCACTAGAGGAAG
GTGTAAGACACAATCCTGATCACATCACTACGACAGCGGTAAAGGTTGATGGCGGCTATCGTTTATCCGGTGATAAAGTA
ATGGTTATTGACGGATACGGCGCAGATGCACTGCTCATCGTTGCTCGTATTAACGATATAACAGCACCGATTAGTTTATT
TTTAGTGCCCAATGATGGACGTTTTAGTCATAAAAAGATGTCTGTAATTGATTCAGGTAATTACACTTCAGTTAAATTTG
AACAAACACTAATAGATGATGAGTCACTATTAACATCGACATTAGTGAGCGCTAAGGTTAACGCAGCTAAAGCTGCACTT
GATGTAGGCCTTGCCCTTGGTCGTTTATGCTTAGCAGCTGAAATGTTAGGTGCCAGCTCTACATTGTTTAATATGACAAT
TGATTACCTAAAAACTCGTGAACAGTTTGATACTAAAATAGGTACATTTCAGGCACTTCAGCATCGAGCCGCAAAATGCT
TTATAGAGTTGGAGTTGACGCGCAGTGCAGTCATTAGTGGGTTTGTTATGGCAGATAAGTTACATAGTCTGTTCCCTGAA
CAATTAGATGATTCAGTTGCGTTATTGCAAGTCATCGATGATATCTCTGCTGCAGCCTCCTTAGCAAAATGGAAAGCGGG
CCAGTTGAGTGACATGATCTCTGGCGAAGCAGTGCAAATGCATGGTGGAATAGGGGTTACCGATGAGTTGGATGTCGGGC
TATATTTAAAACGGATCCGAGTGGCACAAATGAGTCTAGGAGACAGTGACTTTCACTTAACTCAATACGCAGACTTAACC
GCATAA

Upstream 100 bases:

>100_bases
CGGGGGGCTCTTCTGAAGTTCAGTTAAATGTTATCGCTAAAAGAGTCCTCAACTTACCTGATAATAAAGCGGGATCTTCA
GTTAAAAAGGTAACAACATC

Downstream 100 bases:

>100_bases
GTTGATTACCCTATAATAAAAACGCATTAACATTATTGTTAATGCGTTTTTATTTACGCTATTTTTAGCCTAGCTAAATT
GCAACCAGAGGCCCATTTTC

Product: acyl-CoA dehydrogenase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 401; Mature: 401

Protein sequence:

>401_residues
MKLIYNEDERMLADIATEFLESKSPVAAKRALRDQNSDLCFDPHIWQEMAQLGWSGISFAETFGGHGFSHKGLAAIFEAI
GNNLTHSPMLSSVVICGGILQQLAKTNDLSEQHISWLEQIISGDKRIALALEEGVRHNPDHITTTAVKVDGGYRLSGDKV
MVIDGYGADALLIVARINDITAPISLFLVPNDGRFSHKKMSVIDSGNYTSVKFEQTLIDDESLLTSTLVSAKVNAAKAAL
DVGLALGRLCLAAEMLGASSTLFNMTIDYLKTREQFDTKIGTFQALQHRAAKCFIELELTRSAVISGFVMADKLHSLFPE
QLDDSVALLQVIDDISAAASLAKWKAGQLSDMISGEAVQMHGGIGVTDELDVGLYLKRIRVAQMSLGDSDFHLTQYADLT
A

Sequences:

>Translated_401_residues
MKLIYNEDERMLADIATEFLESKSPVAAKRALRDQNSDLCFDPHIWQEMAQLGWSGISFAETFGGHGFSHKGLAAIFEAI
GNNLTHSPMLSSVVICGGILQQLAKTNDLSEQHISWLEQIISGDKRIALALEEGVRHNPDHITTTAVKVDGGYRLSGDKV
MVIDGYGADALLIVARINDITAPISLFLVPNDGRFSHKKMSVIDSGNYTSVKFEQTLIDDESLLTSTLVSAKVNAAKAAL
DVGLALGRLCLAAEMLGASSTLFNMTIDYLKTREQFDTKIGTFQALQHRAAKCFIELELTRSAVISGFVMADKLHSLFPE
QLDDSVALLQVIDDISAAASLAKWKAGQLSDMISGEAVQMHGGIGVTDELDVGLYLKRIRVAQMSLGDSDFHLTQYADLT
A
>Mature_401_residues
MKLIYNEDERMLADIATEFLESKSPVAAKRALRDQNSDLCFDPHIWQEMAQLGWSGISFAETFGGHGFSHKGLAAIFEAI
GNNLTHSPMLSSVVICGGILQQLAKTNDLSEQHISWLEQIISGDKRIALALEEGVRHNPDHITTTAVKVDGGYRLSGDKV
MVIDGYGADALLIVARINDITAPISLFLVPNDGRFSHKKMSVIDSGNYTSVKFEQTLIDDESLLTSTLVSAKVNAAKAAL
DVGLALGRLCLAAEMLGASSTLFNMTIDYLKTREQFDTKIGTFQALQHRAAKCFIELELTRSAVISGFVMADKLHSLFPE
QLDDSVALLQVIDDISAAASLAKWKAGQLSDMISGEAVQMHGGIGVTDELDVGLYLKRIRVAQMSLGDSDFHLTQYADLT
A

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501857, Length=358, Percent_Identity=25.6983240223464, Blast_Score=83, Evalue=5e-16,
Organism=Homo sapiens, GI226958412, Length=394, Percent_Identity=23.6040609137056, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI4501859, Length=404, Percent_Identity=23.019801980198, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI4557233, Length=397, Percent_Identity=23.6775818639798, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI226958414, Length=355, Percent_Identity=23.943661971831, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI7656849, Length=395, Percent_Identity=24.0506329113924, Blast_Score=75, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17506239, Length=402, Percent_Identity=24.3781094527363, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17508101, Length=354, Percent_Identity=24.0112994350282, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17538396, Length=394, Percent_Identity=24.1116751269036, Blast_Score=65, Evalue=9e-11,
Organism=Drosophila melanogaster, GI24666513, Length=408, Percent_Identity=23.2843137254902, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI21355753, Length=395, Percent_Identity=23.2911392405063, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21356377, Length=354, Percent_Identity=21.4689265536723, Blast_Score=68, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 43593; Mature: 43593

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLIYNEDERMLADIATEFLESKSPVAAKRALRDQNSDLCFDPHIWQEMAQLGWSGISFA
CCCEECCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCEECCHHHHHHHHCCCCCCCHH
ETFGGHGFSHKGLAAIFEAIGNNLTHSPMLSSVVICGGILQQLAKTNDLSEQHISWLEQI
HHHCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
ISGDKRIALALEEGVRHNPDHITTTAVKVDGGYRLSGDKVMVIDGYGADALLIVARINDI
HCCCCEEEEEEHHCCCCCCCCEEEEEEEECCCEEECCCEEEEEECCCCCEEEEEEECCCC
TAPISLFLVPNDGRFSHKKMSVIDSGNYTSVKFEQTLIDDESLLTSTLVSAKVNAAKAAL
CCCEEEEEEECCCCCCCCEEEEEECCCEEEEEEHHHHCCCHHHHHHHHHHHHHHHHHHHH
DVGLALGRLCLAAEMLGASSTLFNMTIDYLKTREQFDTKIGTFQALQHRAAKCFIELELT
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEH
RSAVISGFVMADKLHSLFPEQLDDSVALLQVIDDISAAASLAKWKAGQLSDMISGEAVQM
HHHHHHHHHHHHHHHHHCHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCEEEE
HGGIGVTDELDVGLYLKRIRVAQMSLGDSDFHLTQYADLTA
CCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEHHCCCCC
>Mature Secondary Structure
MKLIYNEDERMLADIATEFLESKSPVAAKRALRDQNSDLCFDPHIWQEMAQLGWSGISFA
CCCEECCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCEECCHHHHHHHHCCCCCCCHH
ETFGGHGFSHKGLAAIFEAIGNNLTHSPMLSSVVICGGILQQLAKTNDLSEQHISWLEQI
HHHCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
ISGDKRIALALEEGVRHNPDHITTTAVKVDGGYRLSGDKVMVIDGYGADALLIVARINDI
HCCCCEEEEEEHHCCCCCCCCEEEEEEEECCCEEECCCEEEEEECCCCCEEEEEEECCCC
TAPISLFLVPNDGRFSHKKMSVIDSGNYTSVKFEQTLIDDESLLTSTLVSAKVNAAKAAL
CCCEEEEEEECCCCCCCCEEEEEECCCEEEEEEHHHHCCCHHHHHHHHHHHHHHHHHHHH
DVGLALGRLCLAAEMLGASSTLFNMTIDYLKTREQFDTKIGTFQALQHRAAKCFIELELT
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEH
RSAVISGFVMADKLHSLFPEQLDDSVALLQVIDDISAAASLAKWKAGQLSDMISGEAVQM
HHHHHHHHHHHHHHHHHCHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCEEEE
HGGIGVTDELDVGLYLKRIRVAQMSLGDSDFHLTQYADLTA
CCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]