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The map label for this gene is mhpF [C]

Identifier: 167624013

GI number: 167624013

Start: 2514483

End: 2515406

Strand: Reverse

Name: mhpF [C]

Synonym: Shal_2089

Alternate gene names: 167624013

Gene position: 2515406-2514483 (Counterclockwise)

Preceding gene: 167624014

Following gene: 167624012

Centisome position: 48.12

GC content: 46.21

Gene sequence:

>924_bases
ATGACAAGTAAAATAAAATGTGCGCTGATTGGCTCTGGCAATATTGGCACCGACCTACTCTACAAATTAATGCGCAGTGA
TGTGCTTGAGCCTGTATGGATGGTGGGAATCGATCCGGAGTCTGATGGATTAGCTAGAGCTAAAGCCGCCGGGCTGAAGG
TGACCGCAGACGGCATCAATGGCTTACTGCCGTTTGTTGAAGCCGATGAGATTAAAATCGCCTTTGATGCTACATCTGCA
TACGTACATGCAGAGAACTCACGAAAATTAAATGAATTAGGGGTGGTGATGATTGACTTAACCCCAGCGGCAATTGGTCC
TTTTTGCGTTCCCCCGGTTAACCTTTCTCAACTCGATGAAAATGTAAAAAATATTAATATGGTCACCTGCGGCGGCCAAG
CAACTATCCCAATGGTTGCTGCGGTTTCACGAGTACAAGCGGTAGAGTACGGCGAAATTGTTGCTACGGTTTCATCCCGC
TCTGTAGGCCCCGGTACTCGGCAAAACATTGATGAGTTTACTCGTACAACGGCTGGCGCAGTGGAACAAATTGGTGGTGC
AGAAAAAGGCAAAGCGATTATTGTCATTAACCCTGCTGAACCGCCGTTATTGATGCGAGATACCATTCACTGCCTAACAA
AAGAACAACCTGATGAACAGGCAATTACAGCATCTGTCCACGAGATGATTGAACAAGTTCAACAGTATGTACCGGGTTAC
ACACTTAAAAATGGTCCTGTATTTGATGGCCGTAAAGTCACCATATTTTTAGAAGTTGAAGGTCTTGGAGATTACTTACC
AAAGTACGCAGGTAACCTCGACATAATGACCGCCGCAGCAGCAAGAACAGCAGAGATGCTAGCGTCCAAAATGCTCAATC
CTGAACCCCATTACAATGTTACCCAAGAAGCGGCGCTAGCCTAG

Upstream 100 bases:

>100_bases
AATTCACCATGGAAATTGAAGGCTTGGGAAGCTGCAGCATCAGCTTTTGCGACTAACACAGATTAGACATCAGCACGGAA
ATAACAGAAGGAATACCGAC

Downstream 100 bases:

>100_bases
GAGTCCATGATGAATTTAACGGGAAAAAAAGTTATTTTACACGACATGTCATTAAGAGATGGCATGCATGCTCGCCAACA
TCAAATTACTTTGAAAGAGA

Product: acetaldehyde dehydrogenase

Products: NA

Alternate protein names: Acetaldehyde dehydrogenase [acetylating]

Number of amino acids: Translated: 307; Mature: 306

Protein sequence:

>307_residues
MTSKIKCALIGSGNIGTDLLYKLMRSDVLEPVWMVGIDPESDGLARAKAAGLKVTADGINGLLPFVEADEIKIAFDATSA
YVHAENSRKLNELGVVMIDLTPAAIGPFCVPPVNLSQLDENVKNINMVTCGGQATIPMVAAVSRVQAVEYGEIVATVSSR
SVGPGTRQNIDEFTRTTAGAVEQIGGAEKGKAIIVINPAEPPLLMRDTIHCLTKEQPDEQAITASVHEMIEQVQQYVPGY
TLKNGPVFDGRKVTIFLEVEGLGDYLPKYAGNLDIMTAAAARTAEMLASKMLNPEPHYNVTQEAALA

Sequences:

>Translated_307_residues
MTSKIKCALIGSGNIGTDLLYKLMRSDVLEPVWMVGIDPESDGLARAKAAGLKVTADGINGLLPFVEADEIKIAFDATSA
YVHAENSRKLNELGVVMIDLTPAAIGPFCVPPVNLSQLDENVKNINMVTCGGQATIPMVAAVSRVQAVEYGEIVATVSSR
SVGPGTRQNIDEFTRTTAGAVEQIGGAEKGKAIIVINPAEPPLLMRDTIHCLTKEQPDEQAITASVHEMIEQVQQYVPGY
TLKNGPVFDGRKVTIFLEVEGLGDYLPKYAGNLDIMTAAAARTAEMLASKMLNPEPHYNVTQEAALA
>Mature_306_residues
TSKIKCALIGSGNIGTDLLYKLMRSDVLEPVWMVGIDPESDGLARAKAAGLKVTADGINGLLPFVEADEIKIAFDATSAY
VHAENSRKLNELGVVMIDLTPAAIGPFCVPPVNLSQLDENVKNINMVTCGGQATIPMVAAVSRVQAVEYGEIVATVSSRS
VGPGTRQNIDEFTRTTAGAVEQIGGAEKGKAIIVINPAEPPLLMRDTIHCLTKEQPDEQAITASVHEMIEQVQQYVPGYT
LKNGPVFDGRKVTIFLEVEGLGDYLPKYAGNLDIMTAAAARTAEMLASKMLNPEPHYNVTQEAALA

Specific function: Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta- cleavage pathway for the degradation of aromatic compounds

COG id: COG4569

COG function: function code Q; Acetaldehyde dehydrogenase (acetylating)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetaldehyde dehydrogenase family

Homologues:

Organism=Escherichia coli, GI1786547, Length=309, Percent_Identity=55.9870550161812, Blast_Score=319, Evalue=1e-88,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACDH_SHEHH (B0TTT0)

Other databases:

- EMBL:   CP000931
- RefSeq:   YP_001674307.1
- ProteinModelPortal:   B0TTT0
- SMR:   B0TTT0
- GeneID:   5902820
- GenomeReviews:   CP000931_GR
- KEGG:   shl:Shal_2089
- HOGENOM:   HBG300125
- OMA:   IGGAQRG
- ProtClustDB:   PRK08300
- BioCyc:   SHAL458817:SHAL_2089-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01657
- InterPro:   IPR003361
- InterPro:   IPR015426
- InterPro:   IPR016040
- InterPro:   IPR000534
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR21123
- PIRSF:   PIRSF015689
- SMART:   SM00859
- TIGRFAMs:   TIGR03215

Pfam domain/function: PF09290 AcetDehyd-dimer; PF01118 Semialdhyde_dh

EC number: =1.2.1.10

Molecular weight: Translated: 32766; Mature: 32635

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: NA

Important sites: BINDING 272-272

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSKIKCALIGSGNIGTDLLYKLMRSDVLEPVWMVGIDPESDGLARAKAAGLKVTADGIN
CCCCEEEEEEECCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHCCCEEEECCCC
GLLPFVEADEIKIAFDATSAYVHAENSRKLNELGVVMIDLTPAAIGPFCVPPVNLSQLDE
CCCCCEECCCEEEEEECCEEEEECCCCCCHHHCCEEEEEECHHHCCCCCCCCCCHHHHHH
NVKNINMVTCGGQATIPMVAAVSRVQAVEYGEIVATVSSRSVGPGTRQNIDEFTRTTAGA
HHHEEEEEEECCCCHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCHHHHHHHHHHHHHH
VEQIGGAEKGKAIIVINPAEPPLLMRDTIHCLTKEQPDEQAITASVHEMIEQVQQYVPGY
HHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCE
TLKNGPVFDGRKVTIFLEVEGLGDYLPKYAGNLDIMTAAAARTAEMLASKMLNPEPHYNV
EECCCCEECCEEEEEEEEECCCHHHHHHHCCCCEEEHHHHHHHHHHHHHHHCCCCCCCCC
TQEAALA
CHHHHCC
>Mature Secondary Structure 
TSKIKCALIGSGNIGTDLLYKLMRSDVLEPVWMVGIDPESDGLARAKAAGLKVTADGIN
CCCEEEEEEECCCCCHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHCCCEEEECCCC
GLLPFVEADEIKIAFDATSAYVHAENSRKLNELGVVMIDLTPAAIGPFCVPPVNLSQLDE
CCCCCEECCCEEEEEECCEEEEECCCCCCHHHCCEEEEEECHHHCCCCCCCCCCHHHHHH
NVKNINMVTCGGQATIPMVAAVSRVQAVEYGEIVATVSSRSVGPGTRQNIDEFTRTTAGA
HHHEEEEEEECCCCHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCHHHHHHHHHHHHHH
VEQIGGAEKGKAIIVINPAEPPLLMRDTIHCLTKEQPDEQAITASVHEMIEQVQQYVPGY
HHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCE
TLKNGPVFDGRKVTIFLEVEGLGDYLPKYAGNLDIMTAAAARTAEMLASKMLNPEPHYNV
EECCCCEECCEEEEEEEEECCCHHHHHHHCCCCEEEHHHHHHHHHHHHHHHCCCCCCCCC
TQEAALA
CHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA