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The map label for this gene is dctS [H]

Identifier: 167623988

GI number: 167623988

Start: 2483615

End: 2485399

Strand: Reverse

Name: dctS [H]

Synonym: Shal_2062

Alternate gene names: 167623988

Gene position: 2485399-2483615 (Counterclockwise)

Preceding gene: 167623989

Following gene: 167623987

Centisome position: 47.55

GC content: 44.54

Gene sequence:

>1785_bases
ATGATGATAGCCAAATTTCACCATTTAGCCGCTATAGGCTGCCTTATTTTCTCCTGCTTTAGCTATGCAGAAGACACTGC
GCCAATACGAGTCGGCGTATTGGCATTTACTCACCCAGATAATGTCAAAAAACGCTGGCAACCGACTATCGACAAGATTG
CAGCAGATCTAAATAGGCCTTTTGAACTGTTCGCCCTAACCCCTAGTGAATTAGATTCGGATGTGGCTCAAGGTGAGCTA
GACTTTTTAATCACTAATGCCTTAACTGGGGTGAGCTATAAGAAAGATTTTGGTACCAGTAGCCTATTAACGCTCGTCCC
TCTGAGGAATAAACAACCGACTCAGGCTGTCGGTTCTGCATTAATCACTCGCTCAGATCGACATGTAGCCAATTTTAATG
ATTTGAAAACGCTCAGCGCCGTTTCTACCGATAAGCAAGCATTCGGAGGCTTTCAAATTTTTGCCGGCGAAATGGCTCAC
AACGATTTAAATCCCTTCAATGACTTTGAGCAACTAAGCTTCGTCGGATTCCCTCAGCAAAAGCTACTGTCGATGGTGCT
TAATGGTGAGGCGGATATTGCAATTCTTCCTACTTGTGTACTTGAGAACGCAGTTAAAAACGGTGATATCGCTGCAAATA
GCTTAAAGGTCGTGTTAACCAAAGCTGCTCCAACATTTCACTGTAAAACCTCGAGTGAGTTATACCCCTATTACTCATTT
TCAAAGCTGGGCAAAACAGATCATCGTCTAGCGACCGATGTCATCCGCTCTTTGCTGACGATAAAAACCAATGACCAAGC
GGCAATTATTGGTCGTTACGACTCATGGTCTGCTACGGTAAACGATAGCCATGTATTTAAACTGCTTAAACAGCTACAAC
AATGGCCGTTTGTCACTAACTGGACCTCAATTTTTAAGAGTGCATTCCCCTGGGCCGTCGTAGTCGCAATTTTCTTGTTA
TTGGGTTATATCCATCACCTGCGGGTCAAACGCCTCGTAGTGCTTCGTACACGCGATCTACAGGCCGAAATCGAATTACA
CACCCAGACACAAAAGGCGTTACTTGAACAAACAAAGCAGTTCTATAAGGCTCAACGGGTACTGTTAACGGGTGAGATGG
CATCGGGTATAGCCCATGAGCTGAATCAACCCTTAGCGGGGATCCGCTATCTGACTCAGGGTTGCATTTACCGTTTGTCT
GAAGAGCAGACCGATCTTAAAGACGCCATGACCAAAGCGATTCAACAAGTCGATCGGGCTCAATCGACGATTAAACGCTT
TAGGCATTTCTGCCAACAACCCAGTGTGATGAGTGAGTGTAGTTTAAATCAGGTCTTAGATGAAACATTGAGCCTTATGG
GTGCCGAGTTCACGCGTATGCAACTAACGCCAGAGTTTAGGAGTGAAACAGTGCAGTTAACGGCAGATCCGAGTCTTCTA
CAGCAAGTGTTCGTCAATATCATACGCAATGCACTCGATGCGATGGCGCAAACCCCTGAACCGAGCCTTTCTATAACGCT
TTCAAAGCAAGCACAACACGCCACTATTGTATTTAAGGATAATGGCACGGGTTTGACTGAAATAGCGTTAGAGCGGTTAT
TCTTCCCGTTTGAAACATCAAAAGAAAATGGCTTGGGGCTCGGTATGATCATTTGTAAACGTATTATTGAGGAGCACGCC
GGTGAGATAAAGGCTAAAAACAATTGCAACAAATATACTAAGCAGCGTGAGCCAGGTTTAAGCATGACTATCACCCTTCC
AATTAAGGAACCATTAAATGACTAA

Upstream 100 bases:

>100_bases
TTCGAACACAAACTGCGATTCATGTCACGTAGTGTCGGTCTGCACACTACATTTATCTATAATGAAGTCATAATACTCAA
GTGTCTCCTTTCTGTACTCA

Downstream 100 bases:

>100_bases
TCTGTATCTGGTAGACGATGATCAGGCTGTACTAGACTCGTTAACCTGGATGTTAAATGGACTTGGATATCAACCTAAAG
GCTTTTTATCGGCCGATTCA

Product: histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 594; Mature: 594

Protein sequence:

>594_residues
MMIAKFHHLAAIGCLIFSCFSYAEDTAPIRVGVLAFTHPDNVKKRWQPTIDKIAADLNRPFELFALTPSELDSDVAQGEL
DFLITNALTGVSYKKDFGTSSLLTLVPLRNKQPTQAVGSALITRSDRHVANFNDLKTLSAVSTDKQAFGGFQIFAGEMAH
NDLNPFNDFEQLSFVGFPQQKLLSMVLNGEADIAILPTCVLENAVKNGDIAANSLKVVLTKAAPTFHCKTSSELYPYYSF
SKLGKTDHRLATDVIRSLLTIKTNDQAAIIGRYDSWSATVNDSHVFKLLKQLQQWPFVTNWTSIFKSAFPWAVVVAIFLL
LGYIHHLRVKRLVVLRTRDLQAEIELHTQTQKALLEQTKQFYKAQRVLLTGEMASGIAHELNQPLAGIRYLTQGCIYRLS
EEQTDLKDAMTKAIQQVDRAQSTIKRFRHFCQQPSVMSECSLNQVLDETLSLMGAEFTRMQLTPEFRSETVQLTADPSLL
QQVFVNIIRNALDAMAQTPEPSLSITLSKQAQHATIVFKDNGTGLTEIALERLFFPFETSKENGLGLGMIICKRIIEEHA
GEIKAKNNCNKYTKQREPGLSMTITLPIKEPLND

Sequences:

>Translated_594_residues
MMIAKFHHLAAIGCLIFSCFSYAEDTAPIRVGVLAFTHPDNVKKRWQPTIDKIAADLNRPFELFALTPSELDSDVAQGEL
DFLITNALTGVSYKKDFGTSSLLTLVPLRNKQPTQAVGSALITRSDRHVANFNDLKTLSAVSTDKQAFGGFQIFAGEMAH
NDLNPFNDFEQLSFVGFPQQKLLSMVLNGEADIAILPTCVLENAVKNGDIAANSLKVVLTKAAPTFHCKTSSELYPYYSF
SKLGKTDHRLATDVIRSLLTIKTNDQAAIIGRYDSWSATVNDSHVFKLLKQLQQWPFVTNWTSIFKSAFPWAVVVAIFLL
LGYIHHLRVKRLVVLRTRDLQAEIELHTQTQKALLEQTKQFYKAQRVLLTGEMASGIAHELNQPLAGIRYLTQGCIYRLS
EEQTDLKDAMTKAIQQVDRAQSTIKRFRHFCQQPSVMSECSLNQVLDETLSLMGAEFTRMQLTPEFRSETVQLTADPSLL
QQVFVNIIRNALDAMAQTPEPSLSITLSKQAQHATIVFKDNGTGLTEIALERLFFPFETSKENGLGLGMIICKRIIEEHA
GEIKAKNNCNKYTKQREPGLSMTITLPIKEPLND
>Mature_594_residues
MMIAKFHHLAAIGCLIFSCFSYAEDTAPIRVGVLAFTHPDNVKKRWQPTIDKIAADLNRPFELFALTPSELDSDVAQGEL
DFLITNALTGVSYKKDFGTSSLLTLVPLRNKQPTQAVGSALITRSDRHVANFNDLKTLSAVSTDKQAFGGFQIFAGEMAH
NDLNPFNDFEQLSFVGFPQQKLLSMVLNGEADIAILPTCVLENAVKNGDIAANSLKVVLTKAAPTFHCKTSSELYPYYSF
SKLGKTDHRLATDVIRSLLTIKTNDQAAIIGRYDSWSATVNDSHVFKLLKQLQQWPFVTNWTSIFKSAFPWAVVVAIFLL
LGYIHHLRVKRLVVLRTRDLQAEIELHTQTQKALLEQTKQFYKAQRVLLTGEMASGIAHELNQPLAGIRYLTQGCIYRLS
EEQTDLKDAMTKAIQQVDRAQSTIKRFRHFCQQPSVMSECSLNQVLDETLSLMGAEFTRMQLTPEFRSETVQLTADPSLL
QQVFVNIIRNALDAMAQTPEPSLSITLSKQAQHATIVFKDNGTGLTEIALERLFFPFETSKENGLGLGMIICKRIIEEHA
GEIKAKNNCNKYTKQREPGLSMTITLPIKEPLND

Specific function: Member of the two-component regulatory system dctS/dctR involved in the transport of C4-dicarboxylates. DctS functions as a membrane-associated protein kinase that phosphorylates dctR in response to environmental signals [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=240, Percent_Identity=29.1666666666667, Blast_Score=99, Evalue=8e-22,
Organism=Escherichia coli, GI1790436, Length=236, Percent_Identity=25.8474576271186, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1790300, Length=220, Percent_Identity=29.0909090909091, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1790346, Length=223, Percent_Identity=27.8026905829596, Blast_Score=66, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 66435; Mature: 66435

Theoretical pI: Translated: 7.80; Mature: 7.80

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMIAKFHHLAAIGCLIFSCFSYAEDTAPIRVGVLAFTHPDNVKKRWQPTIDKIAADLNRP
CCEEHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCHHHHCCHHHHHHHHHHCCC
FELFALTPSELDSDVAQGELDFLITNALTGVSYKKDFGTSSLLTLVPLRNKQPTQAVGSA
EEEEEECHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHH
LITRSDRHVANFNDLKTLSAVSTDKQAFGGFQIFAGEMAHNDLNPFNDFEQLSFVGFPQQ
HHCCCCCCCCCCHHHHHHHHHCCCHHHCCCEEEEECHHHCCCCCCCCCHHHHHCCCCCHH
KLLSMVLNGEADIAILPTCVLENAVKNGDIAANSLKVVLTKAAPTFHCKTSSELYPYYSF
HHHHHHHCCCCCEEEEHHHHHHHHHCCCCCCCCCEEEEEEECCCCEEECCCCCCCCCCCH
SKLGKTDHRLATDVIRSLLTIKTNDQAAIIGRYDSWSATVNDSHVFKLLKQLQQWPFVTN
HHCCCCHHHHHHHHHHHHHEECCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCC
WTSIFKSAFPWAVVVAIFLLLGYIHHLRVKRLVVLRTRDLQAEIELHTQTQKALLEQTKQ
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCEEEEEHHHHHHHHHHHHHH
FYKAQRVLLTGEMASGIAHELNQPLAGIRYLTQGCIYRLSEEQTDLKDAMTKAIQQVDRA
HHHHHHHHEECHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
QSTIKRFRHFCQQPSVMSECSLNQVLDETLSLMGAEFTRMQLTPEFRSETVQLTADPSLL
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHEEECCHHHCCCEEEEECCHHHH
QQVFVNIIRNALDAMAQTPEPSLSITLSKQAQHATIVFKDNGTGLTEIALERLFFPFETS
HHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEEEEECCCCCHHHHHHHHHHCCCCCC
KENGLGLGMIICKRIIEEHAGEIKAKNNCNKYTKQREPGLSMTITLPIKEPLND
CCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCCEEEEEEECCCCCCC
>Mature Secondary Structure
MMIAKFHHLAAIGCLIFSCFSYAEDTAPIRVGVLAFTHPDNVKKRWQPTIDKIAADLNRP
CCEEHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCHHHHCCHHHHHHHHHHCCC
FELFALTPSELDSDVAQGELDFLITNALTGVSYKKDFGTSSLLTLVPLRNKQPTQAVGSA
EEEEEECHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHH
LITRSDRHVANFNDLKTLSAVSTDKQAFGGFQIFAGEMAHNDLNPFNDFEQLSFVGFPQQ
HHCCCCCCCCCCHHHHHHHHHCCCHHHCCCEEEEECHHHCCCCCCCCCHHHHHCCCCCHH
KLLSMVLNGEADIAILPTCVLENAVKNGDIAANSLKVVLTKAAPTFHCKTSSELYPYYSF
HHHHHHHCCCCCEEEEHHHHHHHHHCCCCCCCCCEEEEEEECCCCEEECCCCCCCCCCCH
SKLGKTDHRLATDVIRSLLTIKTNDQAAIIGRYDSWSATVNDSHVFKLLKQLQQWPFVTN
HHCCCCHHHHHHHHHHHHHEECCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCC
WTSIFKSAFPWAVVVAIFLLLGYIHHLRVKRLVVLRTRDLQAEIELHTQTQKALLEQTKQ
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCEEEEEHHHHHHHHHHHHHH
FYKAQRVLLTGEMASGIAHELNQPLAGIRYLTQGCIYRLSEEQTDLKDAMTKAIQQVDRA
HHHHHHHHEECHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
QSTIKRFRHFCQQPSVMSECSLNQVLDETLSLMGAEFTRMQLTPEFRSETVQLTADPSLL
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHEEECCHHHCCCEEEEECCHHHH
QQVFVNIIRNALDAMAQTPEPSLSITLSKQAQHATIVFKDNGTGLTEIALERLFFPFETS
HHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEEEEECCCCCHHHHHHHHHHCCCCCC
KENGLGLGMIICKRIIEEHAGEIKAKNNCNKYTKQREPGLSMTITLPIKEPLND
CCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCCEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8455557 [H]