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The map label for this gene is flp [H]

Identifier: 167623966

GI number: 167623966

Start: 2461611

End: 2462768

Strand: Reverse

Name: flp [H]

Synonym: Shal_2040

Alternate gene names: 167623966

Gene position: 2462768-2461611 (Counterclockwise)

Preceding gene: 167623968

Following gene: 167623964

Centisome position: 47.12

GC content: 42.83

Gene sequence:

>1158_bases
ATGTTTTTTAAATCTTTACTCCTGTTCGGTACTTTTTCTATCGGATCATTCTTTCCTGCTCAGCAAGTGCATGCAGCGCA
ATCTCAATATGGCGAGCTTGCAAACAGCTTCAAAAAACGCTTTAACCATGAATTAAAAGATAACAAGCTTCCCGGCGGCG
CTTTTGTCATTGTTGAAGCGGATTCAGTCTTAAAACTTGGGACTTATGGCAAACGAGTAAAAGGTGGTAGCCAAAATATA
GATGCTGACACGGTATTTAGATTAGCGTCTGTCTCTAAAACCTTTGCAGGTACGCTGGCCTCTATGCTCGTTGAAGAGGG
AAAACTAGATTGGCAACAACCTATTATTAGTTATTTGCCAGAATTTGCGTTAGCTAAGCAGCAAAATGTAACACAGATTA
ACCTAGGCCACATTATTGGTCATAGCACAGGCTTAATGCCAAATAGTTATGACAACCTTATCAATGCCAATGTCAAACTC
AGTAAAATTGTCAGTAAATTTGATGAGCTAACCCCCATTTGCAAACCTGGTGTCTGTTATGGCTATCAAAATGTCGCGTT
TTCTTTTATCAAAGATGCTATAGAACAACAATCGACTTTCAGCTACGCGAACTTTATACAGCAACGGATTTTCGCACCAT
TGAGTATGAGCTCTGCCTCTGTTGGCTACGACGCATTTCTAAATGAAAGCAACCGAGCCGAACCCCACGTCAAAACCAAA
TCTGGATTTCAGAAGGTTAAAGTTAAACCTAATTATTATCAACTTGCACCGGCTGCTGGCGTTAATGCCAGCATTAGCGA
TCTTTCAAAATGGTTAATGGCGAATTTAGGTCAAAATCCAGACGTGATCTCAGCGAGTATGATAGAGGATCTAACCACAC
CGGGCGTTAAGACCACAAAAGAGCTACGCCGTAGAGATTGGCGTCCCTACCTTGACAGTGCCCATTACGGTAAAGGTTGG
CGCGTCTATGAGTTCAATGGCCGTCCGCTGATCTACCATGCGGGCTGGGTTGCAGGATATGTTGCTGAAGTATCCTACTC
TCCTGAGTTAAATATCGGTATGGCGATGTTACTCAATGGCGAGTCACGAGTAATCGCAAAATTAAGCTCCGAGTTTTGGC
GCGATGCATTCAAGCAAGCAGATAAACTCGGTATGTGA

Upstream 100 bases:

>100_bases
TAACAAGAACAGCCCCTCATGCATTAAAATGCAACCGTAACGAATTAAACCGCAATAACGATACTAAACAGACCGTATTA
ACGGCACATTGGAACTGTAC

Downstream 100 bases:

>100_bases
CGTTAAGCATGGGCTATTCGCGGTGACATATCTGTAACCGTTAAATTCGTCTTTAATTAGAAATAAAAAAGGATGCCAAT
GGCATCCTTTTTTATTAGAT

Product: beta-lactamase

Products: A Substituted Beta- Amino Acid. [C]

Alternate protein names: FmtA-like protein [H]

Number of amino acids: Translated: 385; Mature: 385

Protein sequence:

>385_residues
MFFKSLLLFGTFSIGSFFPAQQVHAAQSQYGELANSFKKRFNHELKDNKLPGGAFVIVEADSVLKLGTYGKRVKGGSQNI
DADTVFRLASVSKTFAGTLASMLVEEGKLDWQQPIISYLPEFALAKQQNVTQINLGHIIGHSTGLMPNSYDNLINANVKL
SKIVSKFDELTPICKPGVCYGYQNVAFSFIKDAIEQQSTFSYANFIQQRIFAPLSMSSASVGYDAFLNESNRAEPHVKTK
SGFQKVKVKPNYYQLAPAAGVNASISDLSKWLMANLGQNPDVISASMIEDLTTPGVKTTKELRRRDWRPYLDSAHYGKGW
RVYEFNGRPLIYHAGWVAGYVAEVSYSPELNIGMAMLLNGESRVIAKLSSEFWRDAFKQADKLGM

Sequences:

>Translated_385_residues
MFFKSLLLFGTFSIGSFFPAQQVHAAQSQYGELANSFKKRFNHELKDNKLPGGAFVIVEADSVLKLGTYGKRVKGGSQNI
DADTVFRLASVSKTFAGTLASMLVEEGKLDWQQPIISYLPEFALAKQQNVTQINLGHIIGHSTGLMPNSYDNLINANVKL
SKIVSKFDELTPICKPGVCYGYQNVAFSFIKDAIEQQSTFSYANFIQQRIFAPLSMSSASVGYDAFLNESNRAEPHVKTK
SGFQKVKVKPNYYQLAPAAGVNASISDLSKWLMANLGQNPDVISASMIEDLTTPGVKTTKELRRRDWRPYLDSAHYGKGW
RVYEFNGRPLIYHAGWVAGYVAEVSYSPELNIGMAMLLNGESRVIAKLSSEFWRDAFKQADKLGM
>Mature_385_residues
MFFKSLLLFGTFSIGSFFPAQQVHAAQSQYGELANSFKKRFNHELKDNKLPGGAFVIVEADSVLKLGTYGKRVKGGSQNI
DADTVFRLASVSKTFAGTLASMLVEEGKLDWQQPIISYLPEFALAKQQNVTQINLGHIIGHSTGLMPNSYDNLINANVKL
SKIVSKFDELTPICKPGVCYGYQNVAFSFIKDAIEQQSTFSYANFIQQRIFAPLSMSSASVGYDAFLNESNRAEPHVKTK
SGFQKVKVKPNYYQLAPAAGVNASISDLSKWLMANLGQNPDVISASMIEDLTTPGVKTTKELRRRDWRPYLDSAHYGKGW
RVYEFNGRPLIYHAGWVAGYVAEVSYSPELNIGMAMLLNGESRVIAKLSSEFWRDAFKQADKLGM

Specific function: Its precise function is unknown. Has no penicillin- binding activity and is not involved in methicillin resistance [H]

COG id: COG1680

COG function: function code V; Beta-lactamase class C and other penicillin binding proteins

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1790593, Length=391, Percent_Identity=23.2736572890026, Blast_Score=78, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001466 [H]

Pfam domain/function: PF00144 Beta-lactamase [H]

EC number: 3.5.2.6 [C]

Molecular weight: Translated: 42755; Mature: 42755

Theoretical pI: Translated: 9.57; Mature: 9.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFFKSLLLFGTFSIGSFFPAQQVHAAQSQYGELANSFKKRFNHELKDNKLPGGAFVIVEA
CHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCEEEEEEC
DSVLKLGTYGKRVKGGSQNIDADTVFRLASVSKTFAGTLASMLVEEGKLDWQQPIISYLP
CCEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCH
EFALAKQQNVTQINLGHIIGHSTGLMPNSYDNLINANVKLSKIVSKFDELTPICKPGVCY
HHHHHHHCCCCEEEHHHHHCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCC
GYQNVAFSFIKDAIEQQSTFSYANFIQQRIFAPLSMSSASVGYDAFLNESNRAEPHVKTK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCCCCCCCCC
SGFQKVKVKPNYYQLAPAAGVNASISDLSKWLMANLGQNPDVISASMIEDLTTPGVKTTK
CCCEEEEECCCEEEECCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCHHHH
ELRRRDWRPYLDSAHYGKGWRVYEFNGRPLIYHAGWVAGYVAEVSYSPELNIGMAMLLNG
HHHHCCCCCCCCCCCCCCCEEEEEECCCEEEEECCHHHHHHHHCCCCCCCCCCEEEEECC
ESRVIAKLSSEFWRDAFKQADKLGM
CHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MFFKSLLLFGTFSIGSFFPAQQVHAAQSQYGELANSFKKRFNHELKDNKLPGGAFVIVEA
CHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCEEEEEEC
DSVLKLGTYGKRVKGGSQNIDADTVFRLASVSKTFAGTLASMLVEEGKLDWQQPIISYLP
CCEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCH
EFALAKQQNVTQINLGHIIGHSTGLMPNSYDNLINANVKLSKIVSKFDELTPICKPGVCY
HHHHHHHCCCCEEEHHHHHCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCC
GYQNVAFSFIKDAIEQQSTFSYANFIQQRIFAPLSMSSASVGYDAFLNESNRAEPHVKTK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCCCCCCCCC
SGFQKVKVKPNYYQLAPAAGVNASISDLSKWLMANLGQNPDVISASMIEDLTTPGVKTTK
CCCEEEEECCCEEEECCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCHHHH
ELRRRDWRPYLDSAHYGKGWRVYEFNGRPLIYHAGWVAGYVAEVSYSPELNIGMAMLLNG
HHHHCCCCCCCCCCCCCCCEEEEEECCCEEEEECCHHHHHHHHCCCCCCCCCCEEEEECC
ESRVIAKLSSEFWRDAFKQADKLGM
CHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: A Beta-Lactam; H2O [C]

Specific reaction: A Beta-Lactam + H2O = A Substituted Beta- Amino Acid. [C]

General reaction: Carboxylic acid amide hydrolysis [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA