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The map label for this gene is ubiG

Identifier: 167623964

GI number: 167623964

Start: 2457766

End: 2458476

Strand: Reverse

Name: ubiG

Synonym: Shal_2038

Alternate gene names: 167623964

Gene position: 2458476-2457766 (Counterclockwise)

Preceding gene: 167623966

Following gene: 167623963

Centisome position: 47.03

GC content: 43.46

Gene sequence:

>711_bases
GTGCAAACACACAATAATGTTGATCCACAAGAGATCGCTAAGTTTGAGAAAATGGCTGCCACCTGGTGGGATCCTGAAGG
CGAATTTAAGCCACTGCACAACTTAAACCCTTTACGTCTTAATTATATTGATCAAATTGCCGGAGGTATTTTCGGTAAAC
AAGTGCTCGATGTCGGCTGCGGCGGTGGTATTTTATCTGAAAGCATGGCAAAAATTGGTGCCCAAGTAACTGGTCTTGAT
ATGGGTGACGAACCACTTGATGTTGCAAGGCTTCATGCCATAGAAACAGGTGTGTTGATAAACTATGTCAAAAACACCGC
AGAAGCCCATCGAGACGAACATCGTGGGCAATACGACGTTGTTACCTGCATGGAGATGCTTGAGCACGTTCCCAATCCTA
GCTCTGTGATCCAAGCCTGCGCCGATATGGTTAAACCTGGTGGCTTTGTTTTTTTCTCAACAATTAACCGCAACATCCGC
GCCTATGTCGAAACTATTCTTGGCGCTGAATACCTGTTAAAGATGCTACCAGTCGGTACCCATGACCATAATAAGTTTAT
TAAGCCCTCAGAGTTAATTGACTTAGCTGATAAGGCAGAGCTGTTCTGTTCTGATGCAGTCGGTATTACCTACAACCCTA
TCACCGATATCTTTAGATACACCAAGAGTCTTGAAGTTAACTATATGATAGCTACGGTTAAAAATGACTAA

Upstream 100 bases:

>100_bases
ATTGACCACTTTGAAGCTCAACATCACAACTTGTTTGTTTCTTGCCACTATTCATTATAATGTGACGTAAACACGGATTT
GTCACTGAGAGGTAATTTAA

Downstream 100 bases:

>100_bases
CGCCCACTTTACCCTAATCAAAGGCGTGCTATTTGATTTAGATGGCACGCTGGCCGATACAGCACCAGACATGGTAGAAG
CGCTTAATATGACGCTACAA

Product: 3-demethylubiquinone-9 3-methyltransferase

Products: NA

Alternate protein names: 3,4-dihydroxy-5-hexaprenylbenzoate methyltransferase; DHHB methyltransferase

Number of amino acids: Translated: 236; Mature: 236

Protein sequence:

>236_residues
MQTHNNVDPQEIAKFEKMAATWWDPEGEFKPLHNLNPLRLNYIDQIAGGIFGKQVLDVGCGGGILSESMAKIGAQVTGLD
MGDEPLDVARLHAIETGVLINYVKNTAEAHRDEHRGQYDVVTCMEMLEHVPNPSSVIQACADMVKPGGFVFFSTINRNIR
AYVETILGAEYLLKMLPVGTHDHNKFIKPSELIDLADKAELFCSDAVGITYNPITDIFRYTKSLEVNYMIATVKND

Sequences:

>Translated_236_residues
MQTHNNVDPQEIAKFEKMAATWWDPEGEFKPLHNLNPLRLNYIDQIAGGIFGKQVLDVGCGGGILSESMAKIGAQVTGLD
MGDEPLDVARLHAIETGVLINYVKNTAEAHRDEHRGQYDVVTCMEMLEHVPNPSSVIQACADMVKPGGFVFFSTINRNIR
AYVETILGAEYLLKMLPVGTHDHNKFIKPSELIDLADKAELFCSDAVGITYNPITDIFRYTKSLEVNYMIATVKND
>Mature_236_residues
MQTHNNVDPQEIAKFEKMAATWWDPEGEFKPLHNLNPLRLNYIDQIAGGIFGKQVLDVGCGGGILSESMAKIGAQVTGLD
MGDEPLDVARLHAIETGVLINYVKNTAEAHRDEHRGQYDVVTCMEMLEHVPNPSSVIQACADMVKPGGFVFFSTINRNIR
AYVETILGAEYLLKMLPVGTHDHNKFIKPSELIDLADKAELFCSDAVGITYNPITDIFRYTKSLEVNYMIATVKND

Specific function: Ubiquinone biosynthesis. [C]

COG id: COG2227

COG function: function code H; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. UbiG/COQ3 family

Homologues:

Organism=Homo sapiens, GI118600965, Length=246, Percent_Identity=32.520325203252, Blast_Score=152, Evalue=3e-37,
Organism=Escherichia coli, GI1788564, Length=228, Percent_Identity=61.8421052631579, Blast_Score=310, Evalue=6e-86,
Organism=Caenorhabditis elegans, GI115533050, Length=245, Percent_Identity=31.0204081632653, Blast_Score=127, Evalue=5e-30,
Organism=Saccharomyces cerevisiae, GI6324476, Length=269, Percent_Identity=30.4832713754647, Blast_Score=126, Evalue=2e-30,
Organism=Drosophila melanogaster, GI281365311, Length=243, Percent_Identity=30.4526748971193, Blast_Score=136, Evalue=1e-32,
Organism=Drosophila melanogaster, GI24585589, Length=264, Percent_Identity=29.1666666666667, Blast_Score=131, Evalue=5e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UBIG_SHEHH (B0TT38)

Other databases:

- EMBL:   CP000931
- RefSeq:   YP_001674258.1
- ProteinModelPortal:   B0TT38
- SMR:   B0TT38
- GeneID:   5905236
- GenomeReviews:   CP000931_GR
- KEGG:   shl:Shal_2038
- HOGENOM:   HBG738842
- OMA:   DHAEIAK
- ProtClustDB:   PRK05134
- BioCyc:   SHAL458817:SHAL_2038-MONOMER
- HAMAP:   MF_00472
- InterPro:   IPR013216
- InterPro:   IPR010233
- TIGRFAMs:   TIGR01983

Pfam domain/function: PF08241 Methyltransf_11

EC number: =2.1.1.64

Molecular weight: Translated: 26229; Mature: 26229

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTHNNVDPQEIAKFEKMAATWWDPEGEFKPLHNLNPLRLNYIDQIAGGIFGKQVLDVGC
CCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
GGGILSESMAKIGAQVTGLDMGDEPLDVARLHAIETGVLINYVKNTAEAHRDEHRGQYDV
CCHHHHHHHHHHCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
VTCMEMLEHVPNPSSVIQACADMVKPGGFVFFSTINRNIRAYVETILGAEYLLKMLPVGT
HHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEEHHCHHHHHHHHHHHHHHHHHHHHCCCC
HDHNKFIKPSELIDLADKAELFCSDAVGITYNPITDIFRYTKSLEVNYMIATVKND
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCEECHHHHHHHHHHCCEEEEEEEEEECC
>Mature Secondary Structure
MQTHNNVDPQEIAKFEKMAATWWDPEGEFKPLHNLNPLRLNYIDQIAGGIFGKQVLDVGC
CCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
GGGILSESMAKIGAQVTGLDMGDEPLDVARLHAIETGVLINYVKNTAEAHRDEHRGQYDV
CCHHHHHHHHHHCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
VTCMEMLEHVPNPSSVIQACADMVKPGGFVFFSTINRNIRAYVETILGAEYLLKMLPVGT
HHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEEHHCHHHHHHHHHHHHHHHHHHHHCCCC
HDHNKFIKPSELIDLADKAELFCSDAVGITYNPITDIFRYTKSLEVNYMIATVKND
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCEECHHHHHHHHHHCCEEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA