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The map label for this gene is mdtA [H]

Identifier: 167623903

GI number: 167623903

Start: 2374460

End: 2375581

Strand: Direct

Name: mdtA [H]

Synonym: Shal_1974

Alternate gene names: 167623903

Gene position: 2374460-2375581 (Clockwise)

Preceding gene: 167623899

Following gene: 167623904

Centisome position: 45.43

GC content: 48.31

Gene sequence:

>1122_bases
ATGAATCTTAAACCATCAGCCTTGCACCCTTTCAAGGCAAATTCCCTTGCAGTAAGTATCGTATTAGCCACTGTTTTGAT
GAGTGGATGCGATAAGGAGGAGGTGCAGGTTGTTGCTGCGCCTGTTATTAGGCCTGTACTGAGTGAAATAGTATCCAGTC
AAGTGGGTGATGAGTTGAGCTTTAATGGCGTAGTTCGCGCCGCAGAGCGCGCCGAACTCGCGTTTCAAGTCGGTGGTCGT
CTTATCAATATTTTGGTGAAAGAGGGTGATGAGGTTAAGCAGGGGCAGGTGCTCGCCAGGCTAGATGCACGAGATGCCAC
CACAGCGCTGGAGTCTGCTCAGTTGGAGCTTAAAAATACAGCGCTCGATCACAACCGAGCCCTAGTGGTGTATGAAAAGA
GCCAAGCTATCTCTAAAAGTGAATTGGACACCATTACCACACGCTTAGAACTCGCGAGAAATCATGTCGAAGATGCCACT
CTTCAGCTTGAATATACCGAGCTAAAAGCGCCATTTGCTGGCATTATCGGCCGAAAATTGGTGGATAATCATATCCAGAT
CCAAGCGAATACACCTGTATTCATCTTGCACGATCTGAGTGATTTAGAGGTGGTGATTAATATTCCCCATAAGGTGATGC
TCTCAAGCGCAATCGCTTCCAAGGCGAATGCTGAGCTGTCTGCTATTCCAGGAACCTTGTTTCCACTCGCGCTTCGCACA
TTCGGCACCCAAGCCGACGCCGTATCGCAAACATACCCGGTGGTATTGGGTTTTGACGATCTAAAAGGGTTTCGTGTATT
GCCAGGTATGGCGGTCAAAGTGGTGCCCAGCAGTGCAAGCACTATCCAAAATGTTAGCCCAAATGCTAGCCAAAATGCTT
CAAACCTGACTATTCCGTTAACAGCTGTGGTGCCAGACAACCAAGGTAAGCAGTTTGTATGGGTGGTTGGCAGTGACAAT
AAAGCGCAGAAACGTTTTATCGAGTTGGGTGCGCTAAGTAAAAATCGCATTGTGGTGAAAAGTAACCTCGCAGTTGGTGA
GCGGGTGATCATTGCCGGTGTCTCAAGTGTAAGAGAGGGCATGCAGGTACGCCCTTATACTGACACCAATAGCGGAGCTT
AA

Upstream 100 bases:

>100_bases
AGATCCTTAATGAAACAGCGTTAATGAGCTGGGCTTGCAGAGCAAATACATATCAATAGTGGTCGCGCCGACCCTTCTTT
AAGTGGAGAAATAGGTGAAA

Downstream 100 bases:

>100_bases
CCGATGGGCATTGCACGATATACTATTGCCAAACGCACCAGTGTCTGGGTATTAATTGCCCTGATATTGCTCGGTGGCTA
TATCAGTTACTTGAAGCTTG

Product: RND family efflux transporter MFP subunit

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 373; Mature: 373

Protein sequence:

>373_residues
MNLKPSALHPFKANSLAVSIVLATVLMSGCDKEEVQVVAAPVIRPVLSEIVSSQVGDELSFNGVVRAAERAELAFQVGGR
LINILVKEGDEVKQGQVLARLDARDATTALESAQLELKNTALDHNRALVVYEKSQAISKSELDTITTRLELARNHVEDAT
LQLEYTELKAPFAGIIGRKLVDNHIQIQANTPVFILHDLSDLEVVINIPHKVMLSSAIASKANAELSAIPGTLFPLALRT
FGTQADAVSQTYPVVLGFDDLKGFRVLPGMAVKVVPSSASTIQNVSPNASQNASNLTIPLTAVVPDNQGKQFVWVVGSDN
KAQKRFIELGALSKNRIVVKSNLAVGERVIIAGVSSVREGMQVRPYTDTNSGA

Sequences:

>Translated_373_residues
MNLKPSALHPFKANSLAVSIVLATVLMSGCDKEEVQVVAAPVIRPVLSEIVSSQVGDELSFNGVVRAAERAELAFQVGGR
LINILVKEGDEVKQGQVLARLDARDATTALESAQLELKNTALDHNRALVVYEKSQAISKSELDTITTRLELARNHVEDAT
LQLEYTELKAPFAGIIGRKLVDNHIQIQANTPVFILHDLSDLEVVINIPHKVMLSSAIASKANAELSAIPGTLFPLALRT
FGTQADAVSQTYPVVLGFDDLKGFRVLPGMAVKVVPSSASTIQNVSPNASQNASNLTIPLTAVVPDNQGKQFVWVVGSDN
KAQKRFIELGALSKNRIVVKSNLAVGERVIIAGVSSVREGMQVRPYTDTNSGA
>Mature_373_residues
MNLKPSALHPFKANSLAVSIVLATVLMSGCDKEEVQVVAAPVIRPVLSEIVSSQVGDELSFNGVVRAAERAELAFQVGGR
LINILVKEGDEVKQGQVLARLDARDATTALESAQLELKNTALDHNRALVVYEKSQAISKSELDTITTRLELARNHVEDAT
LQLEYTELKAPFAGIIGRKLVDNHIQIQANTPVFILHDLSDLEVVINIPHKVMLSSAIASKANAELSAIPGTLFPLALRT
FGTQADAVSQTYPVVLGFDDLKGFRVLPGMAVKVVPSSASTIQNVSPNASQNASNLTIPLTAVVPDNQGKQFVWVVGSDN
KAQKRFIELGALSKNRIVVKSNLAVGERVIIAGVSSVREGMQVRPYTDTNSGA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=322, Percent_Identity=27.3291925465839, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1789929, Length=392, Percent_Identity=25, Blast_Score=77, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 39982; Mature: 39982

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLKPSALHPFKANSLAVSIVLATVLMSGCDKEEVQVVAAPVIRPVLSEIVSSQVGDELS
CCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHEEHHHHHHHHHHHHHHHHHCCCCCC
FNGVVRAAERAELAFQVGGRLINILVKEGDEVKQGQVLARLDARDATTALESAQLELKNT
CCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCEEEEECCCHHHHHHHHHHEEEHHC
ALDHNRALVVYEKSQAISKSELDTITTRLELARNHVEDATLQLEYTELKAPFAGIIGRKL
CCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHCCCHHHHHHHHH
VDNHIQIQANTPVFILHDLSDLEVVINIPHKVMLSSAIASKANAELSAIPGTLFPLALRT
CCCEEEEEECCCEEEEECCCCEEEEEECCHHHHHHHHHHHHCCCCEEECCCHHHHHHHHH
FGTQADAVSQTYPVVLGFDDLKGFRVLPGMAVKVVPSSASTIQNVSPNASQNASNLTIPL
HCCCCHHCCCCCCEEEEECCCCCEEECCCCEEEEECCCHHHHHCCCCCCCCCCCCEEEEE
TAVVPDNQGKQFVWVVGSDNKAQKRFIELGALSKNRIVVKSNLAVGERVIIAGVSSVREG
EEEECCCCCCEEEEEEECCCHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEEEHHHHHCC
MQVRPYTDTNSGA
CEECCCCCCCCCC
>Mature Secondary Structure
MNLKPSALHPFKANSLAVSIVLATVLMSGCDKEEVQVVAAPVIRPVLSEIVSSQVGDELS
CCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHEEHHHHHHHHHHHHHHHHHCCCCCC
FNGVVRAAERAELAFQVGGRLINILVKEGDEVKQGQVLARLDARDATTALESAQLELKNT
CCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCEEEEECCCHHHHHHHHHHEEEHHC
ALDHNRALVVYEKSQAISKSELDTITTRLELARNHVEDATLQLEYTELKAPFAGIIGRKL
CCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHCCCHHHHHHHHH
VDNHIQIQANTPVFILHDLSDLEVVINIPHKVMLSSAIASKANAELSAIPGTLFPLALRT
CCCEEEEEECCCEEEEECCCCEEEEEECCHHHHHHHHHHHHCCCCEEECCCHHHHHHHHH
FGTQADAVSQTYPVVLGFDDLKGFRVLPGMAVKVVPSSASTIQNVSPNASQNASNLTIPL
HCCCCHHCCCCCCEEEEECCCCCEEECCCCEEEEECCCHHHHHCCCCCCCCCCCCEEEEE
TAVVPDNQGKQFVWVVGSDNKAQKRFIELGALSKNRIVVKSNLAVGERVIIAGVSSVREG
EEEECCCCCCEEEEEEECCCHHHHHHHHHCCCCCCEEEEEECCCCCCEEEEEEHHHHHCC
MQVRPYTDTNSGA
CEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA