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The map label for this gene is queC

Identifier: 167623865

GI number: 167623865

Start: 2327285

End: 2327974

Strand: Reverse

Name: queC

Synonym: Shal_1935

Alternate gene names: 167623865

Gene position: 2327974-2327285 (Counterclockwise)

Preceding gene: 167623867

Following gene: 167623864

Centisome position: 44.54

GC content: 45.94

Gene sequence:

>690_bases
ATGTCAAAAGCCGTTGTAGTTTTTAGTGGTGGTCAAGATTCGACAACCTGTCTCATTCAGGCCCTCCAACAATTTGATGA
GGTTCACGGGATCACATTCGATTATGGGCAACGACATAGAGAAGAGATTGAAATAGCAAAAGAGTTAGCCACAAACCTCA
AGCTCGCTAGCCACAAAGTAATGGATGTCACCTTGCTCAACGAGTTAGCTATATCCGCACTAACTCGTGATTCAATTCCT
GTTTCCAACGAGTTGATGGATAATGGCCTGCCCAACACCTTTGTACCTGGCAGAAATATACTGTTTCTGACTTTAGCTGG
CATTTATGCCTACCAGCTGGGTGCCGATACTGTGATAACTGGCGTATGCGAGACTGATTTTTCAGGCTACCCAGATTGCC
GCAATGACTTTGTTAAAGCCATGCAAGCCGCTCTTGAACAAGGTATGGATAAAAAACTCACCATTCAGACTCCGCTGATG
TGGCTAGACAAGGCCGAGACATGGGCTCTTGCAGACAAGTTTGATAGCTTGGAGCTTGTACGTAATGAAACCTTAACCTG
CTATAACGGCATTAAAGGCGACGGTTGCGGTACCTGCCCGGCGTGTCTACTTCGAAAACGCGGTCTTGAAGAGTACCTTG
CAGACAAAGAAGCGATACAAGCAAGACTCTCGGCTAAATGCGAAAACTAA

Upstream 100 bases:

>100_bases
ACTTTATAGAGGATTTTAACGTGAGTCGCAAGTAGTTTAAAAGCATTCACGGCTGCGCTAAACTAATAGCTCTTATTTAT
TACTAGATTAAAAGTTTATT

Downstream 100 bases:

>100_bases
AAATGGGGGCCAACAGCCCCTATACATTTGCGCTTATCATTACAATTATTTGCATTAGTCTTTTTTATCTGCAACTCGAT
TCGCTGCTCGCCTACCAGAG

Product: exsB protein

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine synthase; PreQ(0) synthase; Queuosine biosynthesis protein queC

Number of amino acids: Translated: 229; Mature: 228

Protein sequence:

>229_residues
MSKAVVVFSGGQDSTTCLIQALQQFDEVHGITFDYGQRHREEIEIAKELATNLKLASHKVMDVTLLNELAISALTRDSIP
VSNELMDNGLPNTFVPGRNILFLTLAGIYAYQLGADTVITGVCETDFSGYPDCRNDFVKAMQAALEQGMDKKLTIQTPLM
WLDKAETWALADKFDSLELVRNETLTCYNGIKGDGCGTCPACLLRKRGLEEYLADKEAIQARLSAKCEN

Sequences:

>Translated_229_residues
MSKAVVVFSGGQDSTTCLIQALQQFDEVHGITFDYGQRHREEIEIAKELATNLKLASHKVMDVTLLNELAISALTRDSIP
VSNELMDNGLPNTFVPGRNILFLTLAGIYAYQLGADTVITGVCETDFSGYPDCRNDFVKAMQAALEQGMDKKLTIQTPLM
WLDKAETWALADKFDSLELVRNETLTCYNGIKGDGCGTCPACLLRKRGLEEYLADKEAIQARLSAKCEN
>Mature_228_residues
SKAVVVFSGGQDSTTCLIQALQQFDEVHGITFDYGQRHREEIEIAKELATNLKLASHKVMDVTLLNELAISALTRDSIPV
SNELMDNGLPNTFVPGRNILFLTLAGIYAYQLGADTVITGVCETDFSGYPDCRNDFVKAMQAALEQGMDKKLTIQTPLMW
LDKAETWALADKFDSLELVRNETLTCYNGIKGDGCGTCPACLLRKRGLEEYLADKEAIQARLSAKCEN

Specific function: Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))

COG id: COG0603

COG function: function code R; Predicted PP-loop superfamily ATPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the queC family

Homologues:

Organism=Escherichia coli, GI1786648, Length=227, Percent_Identity=70.0440528634361, Blast_Score=339, Evalue=1e-94,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): QUEC_SHEHH (B0TSC0)

Other databases:

- EMBL:   CP000931
- RefSeq:   YP_001674159.1
- ProteinModelPortal:   B0TSC0
- SMR:   B0TSC0
- GeneID:   5906917
- GenomeReviews:   CP000931_GR
- KEGG:   shl:Shal_1935
- HOGENOM:   HBG553284
- OMA:   CETDYSG
- ProtClustDB:   CLSK982142
- BioCyc:   SHAL458817:SHAL_1935-MONOMER
- HAMAP:   MF_01633_B
- InterPro:   IPR018317
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PIRSF:   PIRSF006293
- TIGRFAMs:   TIGR00364

Pfam domain/function: PF06508 ExsB

EC number: NA

Molecular weight: Translated: 25266; Mature: 25135

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
3.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKAVVVFSGGQDSTTCLIQALQQFDEVHGITFDYGQRHREEIEIAKELATNLKLASHKV
CCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
MDVTLLNELAISALTRDSIPVSNELMDNGLPNTFVPGRNILFLTLAGIYAYQLGADTVIT
HHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHEE
GVCETDFSGYPDCRNDFVKAMQAALEQGMDKKLTIQTPLMWLDKAETWALADKFDSLELV
EECCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHCCCHHHHHHHHHHHHHHH
RNETLTCYNGIKGDGCGTCPACLLRKRGLEEYLADKEAIQARLSAKCEN
HCCCEEEECCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SKAVVVFSGGQDSTTCLIQALQQFDEVHGITFDYGQRHREEIEIAKELATNLKLASHKV
CCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
MDVTLLNELAISALTRDSIPVSNELMDNGLPNTFVPGRNILFLTLAGIYAYQLGADTVIT
HHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHEE
GVCETDFSGYPDCRNDFVKAMQAALEQGMDKKLTIQTPLMWLDKAETWALADKFDSLELV
EECCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHCCCHHHHHHHHHHHHHHH
RNETLTCYNGIKGDGCGTCPACLLRKRGLEEYLADKEAIQARLSAKCEN
HCCCEEEECCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA