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The map label for this gene is fadE [H]

Identifier: 167623820

GI number: 167623820

Start: 2271270

End: 2273717

Strand: Reverse

Name: fadE [H]

Synonym: Shal_1890

Alternate gene names: 167623820

Gene position: 2273717-2271270 (Counterclockwise)

Preceding gene: 167623822

Following gene: 167623815

Centisome position: 43.5

GC content: 49.35

Gene sequence:

>2448_bases
GTGACTACCCTACTATGGATCTTGGCGATGATTTTTACGATTGGCGCTTTTGCCTATCTAAGAGTCGCTCTGCTAACCGC
CACCTTAGGCACCGCGATTGTATTGGCAATCGGAACCGGCGCCGCAAGTCTAAGCCCATTACTATGGGTAGTGTTTCTTG
CCATTGCTCTTCCCCTTAATGTCAGTTCATTCAGACAAAACGTCATTAGCCGTTCATTATTAAAAATGTATCGTGGGATC
ATGCCCGAGATGTCTTCGACAGAAAAAGAAGCCATCGAAGCGGGAACCACCTGGTGGGAAGCAGACCTATTTGCTGGTAA
GCCCGACTGGAGCAAACTGCACAACTACCCAAAGGCGAGCTTAACCGCTGAAGAGCAAGCCTTCTTAGACGGCCCTGTCG
AAGAAGTTTGCCGCATGGTAAACCAGCATCAAGTGTCTCATGAGCTTGCCGACCTTCCTGATGAAGTGTGGCAATACCTG
AAAGATCACGGTTTCTTTGCGATGATCATCAAAAAGAAATACGGTGGTTTAGAATATTCAGCCTATGCCCAATCACGCGT
ATTACAAAAGCTTGCAGGCCTAAGCAGTGAACTCGCGTCAACGGTTGGCGTGCCTAACTCATTAGGACCTGGTGAGTTAC
TACAACACTATGGCACCCCAGCTCAGCAAGACCATTATCTACCTCGCCTTGCTAAAGGCTTAGAAGTTCCTTGTTTTGCC
CTTACCAGCCCTGAAGCGGGTAGTGATGCGGGTGCGATTCCTGATTACGGTGTTGTCTGTAAAGGCGAATGGGAAGGCGA
AGAAGTTCTCGGTATGAAGCTTACCTGGAACAAGCGCTATATTACCCTTGCCCCTACGGCAACGGTATTGGGTCTTGCAT
TTAAACTACGCGATCCAGACCAACTGCTAGGCAATCAAGAAGAGCTCGGCATTACCTGCGCGCTTATTCCTACCGATATT
GAAGGGGTAGAAACGGGTCGTCGTCACTTCCCGCTTAACTGTATGTTCCAAAACGGACCAACTCGTGGCACAGATGTGTT
TGTACCGCTGAGCTTTATCATTGGCGGCGTTGAGATGGCTGGCCAAGGCTGGAGAATGTTGGTTGAGTGCCTTTCCGTTG
GCCGAGGCATCACTCTGCCCTCAAACTCAGCAGGTGGTATTAAAACGGCTGCCGTTGCGACTGGCGCTTATGCCCGCATT
CGTCGCCAATTTAAGCTGCCTATCGGCAAACTAGAAGGGATCGAAGAGCCAATGGCACGCATTGGCGGTAACGCTTATTT
GATGGATGCGGTAACCACACTCACCACAACGGCTATTGATCTGGGCGAAAAGCCATCGGTGATCTCGGCAATTGTGAAAT
ACCACCTCACTGACAGAATGCAACGATGCGTTATCGATGCCATGGATATTCATGGTGGTAAAGGCGTTTGCTTAGGCCCA
AATAACTACTTAGGCCGTGGTTACCAGGCAGCACCCATCGCTATTACCGTAGAAGGTGCAAACATCCTCACTCGCTCGAT
GATCATCTATGGTCAAGGCGCAATTCGTTGCCATCCCTATGTATTAGCCGAGATGGAATCGGCGTTTGATCCAGATGCAA
ACAAGGGTCTACGCGATTTTGATGCAGCCATCTTTGGCCATATCGGCTTCACCACCAGCAACCTAGTTCGTAGCTTGTGG
ATGGGTCTGACTTCAAGCTACTTCTCTAACGCGCCTTATGCTGATAAGACCAAGCGTTACTATCAGCAGATGAACCGCTT
TAGTGCGAACTTAGCCCTGTTATCTGACTTAGCGATGGCGACCCTTGGGGGCAACCTTAAACGGAAAGAGCGGATTTCTG
CCCGCCTTGGCGACCTACTCAGTCAGCTCTATCTGGCTTCAGCAACGCTTAAGCGTTATGAAGATGAAGGCCGACTCACT
GAAGACTTGCCTCTCGTGCAATGGGCCGTAGAGGACGCCTTATACAAGTTGCAGTCTTCACTCGATGATCTGTTAGATAA
TTTCCCTATGGGACTCGGTATCGCGCTACGCGTCATTATCTTCCCATTTGGTCGTCCACTTAAGCGCCCAAGTGACGTGC
TTGACCACAAGGTTGCTAAAATCATGCAAACGCCTTGTGCAAGCCGTGAGCGTTTAGGTAAAGGACAATTTTGGACGCCG
AGTGAGCATAATGCAGTGGGTATTCAAGAGCAGACCTTTAAAGATATTATTGCCTCTGAGCCTATCTACGACAAAGTCTG
TAAGGCAGCAGGAAAACGCCTACCCTTTATGTGGCTAGATAAAATCGCTGCCGAAGGTAAAGCTCTAGGCGTACTGAGCG
AAGAGGAAGTGGCACTACTCGAACGCGCCGAAATTGGTCGCATGAAGTCTATCAACGTCGATGATTTTGATCATGAAGAG
TTAAAAGCACGCACACTTGAGTACACAAAAGAGGTGCAAGCGGCTTAG

Upstream 100 bases:

>100_bases
TTATGAGACACAGGTCTGACCACACACTACAATTGTGAGATAAACCTCAAAACAAGTGCCTTTAGGTCAACTATAGGTCA
CACATAAAAGGAGAATTACA

Downstream 100 bases:

>100_bases
TCCGCTGTAAGTATCTCAACCAATAAAAAGGCCTAAGTGGATCACTTAGGCCTTTTTATTTATCTGTATATCCCGTCCAG
AGAGAAGTTGACACTACAGA

Product: acyl-CoA dehydrogenase

Products: NA

Alternate protein names: ACDH [H]

Number of amino acids: Translated: 815; Mature: 814

Protein sequence:

>815_residues
MTTLLWILAMIFTIGAFAYLRVALLTATLGTAIVLAIGTGAASLSPLLWVVFLAIALPLNVSSFRQNVISRSLLKMYRGI
MPEMSSTEKEAIEAGTTWWEADLFAGKPDWSKLHNYPKASLTAEEQAFLDGPVEEVCRMVNQHQVSHELADLPDEVWQYL
KDHGFFAMIIKKKYGGLEYSAYAQSRVLQKLAGLSSELASTVGVPNSLGPGELLQHYGTPAQQDHYLPRLAKGLEVPCFA
LTSPEAGSDAGAIPDYGVVCKGEWEGEEVLGMKLTWNKRYITLAPTATVLGLAFKLRDPDQLLGNQEELGITCALIPTDI
EGVETGRRHFPLNCMFQNGPTRGTDVFVPLSFIIGGVEMAGQGWRMLVECLSVGRGITLPSNSAGGIKTAAVATGAYARI
RRQFKLPIGKLEGIEEPMARIGGNAYLMDAVTTLTTTAIDLGEKPSVISAIVKYHLTDRMQRCVIDAMDIHGGKGVCLGP
NNYLGRGYQAAPIAITVEGANILTRSMIIYGQGAIRCHPYVLAEMESAFDPDANKGLRDFDAAIFGHIGFTTSNLVRSLW
MGLTSSYFSNAPYADKTKRYYQQMNRFSANLALLSDLAMATLGGNLKRKERISARLGDLLSQLYLASATLKRYEDEGRLT
EDLPLVQWAVEDALYKLQSSLDDLLDNFPMGLGIALRVIIFPFGRPLKRPSDVLDHKVAKIMQTPCASRERLGKGQFWTP
SEHNAVGIQEQTFKDIIASEPIYDKVCKAAGKRLPFMWLDKIAAEGKALGVLSEEEVALLERAEIGRMKSINVDDFDHEE
LKARTLEYTKEVQAA

Sequences:

>Translated_815_residues
MTTLLWILAMIFTIGAFAYLRVALLTATLGTAIVLAIGTGAASLSPLLWVVFLAIALPLNVSSFRQNVISRSLLKMYRGI
MPEMSSTEKEAIEAGTTWWEADLFAGKPDWSKLHNYPKASLTAEEQAFLDGPVEEVCRMVNQHQVSHELADLPDEVWQYL
KDHGFFAMIIKKKYGGLEYSAYAQSRVLQKLAGLSSELASTVGVPNSLGPGELLQHYGTPAQQDHYLPRLAKGLEVPCFA
LTSPEAGSDAGAIPDYGVVCKGEWEGEEVLGMKLTWNKRYITLAPTATVLGLAFKLRDPDQLLGNQEELGITCALIPTDI
EGVETGRRHFPLNCMFQNGPTRGTDVFVPLSFIIGGVEMAGQGWRMLVECLSVGRGITLPSNSAGGIKTAAVATGAYARI
RRQFKLPIGKLEGIEEPMARIGGNAYLMDAVTTLTTTAIDLGEKPSVISAIVKYHLTDRMQRCVIDAMDIHGGKGVCLGP
NNYLGRGYQAAPIAITVEGANILTRSMIIYGQGAIRCHPYVLAEMESAFDPDANKGLRDFDAAIFGHIGFTTSNLVRSLW
MGLTSSYFSNAPYADKTKRYYQQMNRFSANLALLSDLAMATLGGNLKRKERISARLGDLLSQLYLASATLKRYEDEGRLT
EDLPLVQWAVEDALYKLQSSLDDLLDNFPMGLGIALRVIIFPFGRPLKRPSDVLDHKVAKIMQTPCASRERLGKGQFWTP
SEHNAVGIQEQTFKDIIASEPIYDKVCKAAGKRLPFMWLDKIAAEGKALGVLSEEEVALLERAEIGRMKSINVDDFDHEE
LKARTLEYTKEVQAA
>Mature_814_residues
TTLLWILAMIFTIGAFAYLRVALLTATLGTAIVLAIGTGAASLSPLLWVVFLAIALPLNVSSFRQNVISRSLLKMYRGIM
PEMSSTEKEAIEAGTTWWEADLFAGKPDWSKLHNYPKASLTAEEQAFLDGPVEEVCRMVNQHQVSHELADLPDEVWQYLK
DHGFFAMIIKKKYGGLEYSAYAQSRVLQKLAGLSSELASTVGVPNSLGPGELLQHYGTPAQQDHYLPRLAKGLEVPCFAL
TSPEAGSDAGAIPDYGVVCKGEWEGEEVLGMKLTWNKRYITLAPTATVLGLAFKLRDPDQLLGNQEELGITCALIPTDIE
GVETGRRHFPLNCMFQNGPTRGTDVFVPLSFIIGGVEMAGQGWRMLVECLSVGRGITLPSNSAGGIKTAAVATGAYARIR
RQFKLPIGKLEGIEEPMARIGGNAYLMDAVTTLTTTAIDLGEKPSVISAIVKYHLTDRMQRCVIDAMDIHGGKGVCLGPN
NYLGRGYQAAPIAITVEGANILTRSMIIYGQGAIRCHPYVLAEMESAFDPDANKGLRDFDAAIFGHIGFTTSNLVRSLWM
GLTSSYFSNAPYADKTKRYYQQMNRFSANLALLSDLAMATLGGNLKRKERISARLGDLLSQLYLASATLKRYEDEGRLTE
DLPLVQWAVEDALYKLQSSLDDLLDNFPMGLGIALRVIIFPFGRPLKRPSDVLDHKVAKIMQTPCASRERLGKGQFWTPS
EHNAVGIQEQTFKDIIASEPIYDKVCKAAGKRLPFMWLDKIAAEGKALGVLSEEEVALLERAEIGRMKSINVDDFDHEEL
KARTLEYTKEVQAA

Specific function: Catalyzes the dehydrogenation of acyl-CoA [H]

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI21361497, Length=552, Percent_Identity=26.268115942029, Blast_Score=124, Evalue=3e-28,
Organism=Homo sapiens, GI4557235, Length=406, Percent_Identity=25.615763546798, Blast_Score=88, Evalue=3e-17,
Organism=Homo sapiens, GI76496475, Length=385, Percent_Identity=25.974025974026, Blast_Score=84, Evalue=4e-16,
Organism=Homo sapiens, GI4557233, Length=420, Percent_Identity=25.7142857142857, Blast_Score=71, Evalue=3e-12,
Organism=Homo sapiens, GI4501859, Length=407, Percent_Identity=24.0786240786241, Blast_Score=67, Evalue=6e-11,
Organism=Escherichia coli, GI87081702, Length=819, Percent_Identity=65.6898656898657, Blast_Score=1098, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17506239, Length=351, Percent_Identity=24.5014245014245, Blast_Score=73, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17538396, Length=323, Percent_Identity=23.2198142414861, Blast_Score=70, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17570075, Length=329, Percent_Identity=24.6200607902736, Blast_Score=66, Evalue=6e-11,
Organism=Drosophila melanogaster, GI281363737, Length=447, Percent_Identity=25.7270693512304, Blast_Score=91, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24646207, Length=361, Percent_Identity=24.9307479224377, Blast_Score=75, Evalue=3e-13,
Organism=Drosophila melanogaster, GI21356377, Length=397, Percent_Identity=25.6926952141058, Blast_Score=72, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21355753, Length=323, Percent_Identity=23.5294117647059, Blast_Score=66, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100
- InterPro:   IPR015396 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N; PF09317 DUF1974 [H]

EC number: NA

Molecular weight: Translated: 89435; Mature: 89304

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTLLWILAMIFTIGAFAYLRVALLTATLGTAIVLAIGTGAASLSPLLWVVFLAIALPLN
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHHHHHHHCCC
VSSFRQNVISRSLLKMYRGIMPEMSSTEKEAIEAGTTWWEADLFAGKPDWSKLHNYPKAS
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCEEECCCCCCCCCHHHHHCCCCCC
LTAEEQAFLDGPVEEVCRMVNQHQVSHELADLPDEVWQYLKDHGFFAMIIKKKYGGLEYS
CCCHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCEEEEEEEHHCCCCCHH
AYAQSRVLQKLAGLSSELASTVGVPNSLGPGELLQHYGTPAQQDHYLPRLAKGLEVPCFA
HHHHHHHHHHHHCCHHHHHHHCCCCCCCCHHHHHHHCCCCCCCCCCHHHHHCCCCCCEEE
LTSPEAGSDAGAIPDYGVVCKGEWEGEEVLGMKLTWNKRYITLAPTATVLGLAFKLRDPD
ECCCCCCCCCCCCCCCCEEECCCCCCCEEEEEEEEECCEEEEECCHHHHHHHHHCCCCHH
QLLGNQEELGITCALIPTDIEGVETGRRHFPLNCMFQNGPTRGTDVFVPLSFIIGGVEMA
HHHCCCHHCCEEEEEECCCCCHHCCCCCCCCEEEEECCCCCCCCEEEEEHHHHHCCHHHC
GQGWRMLVECLSVGRGITLPSNSAGGIKTAAVATGAYARIRRQFKLPIGKLEGIEEPMAR
CCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHCCHHHHHHH
IGGNAYLMDAVTTLTTTAIDLGEKPSVISAIVKYHLTDRMQRCVIDAMDIHGGKGVCLGP
HCCCEEEHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECC
NNYLGRGYQAAPIAITVEGANILTRSMIIYGQGAIRCHPYVLAEMESAFDPDANKGLRDF
CCCCCCCCCCCCEEEEECCCHHHHHEEEEECCCCEEECHHHHHHHHHHCCCCCCCCHHHH
DAAIFGHIGFTTSNLVRSLWMGLTSSYFSNAPYADKTKRYYQQMNRFSANLALLSDLAMA
HHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
TLGGNLKRKERISARLGDLLSQLYLASATLKRYEDEGRLTEDLPLVQWAVEDALYKLQSS
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
LDDLLDNFPMGLGIALRVIIFPFGRPLKRPSDVLDHKVAKIMQTPCASRERLGKGQFWTP
HHHHHHHCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCC
SEHNAVGIQEQTFKDIIASEPIYDKVCKAAGKRLPFMWLDKIAAEGKALGVLSEEEVALL
CCCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHCCCCEEECCCHHHHHHH
ERAEIGRMKSINVDDFDHEELKARTLEYTKEVQAA
HHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TTLLWILAMIFTIGAFAYLRVALLTATLGTAIVLAIGTGAASLSPLLWVVFLAIALPLN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHHHHHHHCCC
VSSFRQNVISRSLLKMYRGIMPEMSSTEKEAIEAGTTWWEADLFAGKPDWSKLHNYPKAS
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCEEECCCCCCCCCHHHHHCCCCCC
LTAEEQAFLDGPVEEVCRMVNQHQVSHELADLPDEVWQYLKDHGFFAMIIKKKYGGLEYS
CCCHHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCEEEEEEEHHCCCCCHH
AYAQSRVLQKLAGLSSELASTVGVPNSLGPGELLQHYGTPAQQDHYLPRLAKGLEVPCFA
HHHHHHHHHHHHCCHHHHHHHCCCCCCCCHHHHHHHCCCCCCCCCCHHHHHCCCCCCEEE
LTSPEAGSDAGAIPDYGVVCKGEWEGEEVLGMKLTWNKRYITLAPTATVLGLAFKLRDPD
ECCCCCCCCCCCCCCCCEEECCCCCCCEEEEEEEEECCEEEEECCHHHHHHHHHCCCCHH
QLLGNQEELGITCALIPTDIEGVETGRRHFPLNCMFQNGPTRGTDVFVPLSFIIGGVEMA
HHHCCCHHCCEEEEEECCCCCHHCCCCCCCCEEEEECCCCCCCCEEEEEHHHHHCCHHHC
GQGWRMLVECLSVGRGITLPSNSAGGIKTAAVATGAYARIRRQFKLPIGKLEGIEEPMAR
CCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHCCHHHHHHH
IGGNAYLMDAVTTLTTTAIDLGEKPSVISAIVKYHLTDRMQRCVIDAMDIHGGKGVCLGP
HCCCEEEHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECC
NNYLGRGYQAAPIAITVEGANILTRSMIIYGQGAIRCHPYVLAEMESAFDPDANKGLRDF
CCCCCCCCCCCCEEEEECCCHHHHHEEEEECCCCEEECHHHHHHHHHHCCCCCCCCHHHH
DAAIFGHIGFTTSNLVRSLWMGLTSSYFSNAPYADKTKRYYQQMNRFSANLALLSDLAMA
HHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
TLGGNLKRKERISARLGDLLSQLYLASATLKRYEDEGRLTEDLPLVQWAVEDALYKLQSS
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
LDDLLDNFPMGLGIALRVIIFPFGRPLKRPSDVLDHKVAKIMQTPCASRERLGKGQFWTP
HHHHHHHCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCC
SEHNAVGIQEQTFKDIIASEPIYDKVCKAAGKRLPFMWLDKIAAEGKALGVLSEEEVALL
CCCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHCCCCEEECCCHHHHHHH
ERAEIGRMKSINVDDFDHEELKARTLEYTKEVQAA
HHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]