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The map label for this gene is kch [H]

Identifier: 167623609

GI number: 167623609

Start: 2012131

End: 2013225

Strand: Reverse

Name: kch [H]

Synonym: Shal_1678

Alternate gene names: 167623609

Gene position: 2013225-2012131 (Counterclockwise)

Preceding gene: 167623610

Following gene: 167623606

Centisome position: 38.52

GC content: 41.28

Gene sequence:

>1095_bases
ATGTCGGCTCAGGTGTTTAGTCCGAAGCAAATCCCACACCTGGCAGATATTAATTTTACAGTACTCACTAATGCACCTTG
GTTCATGCTTGGGGTGTTTTTACTGCTGAACTCTATCGGTTTACTGTTTCGTGCACGTATCGCTTGGGTTATGAGCCTTG
TACTGCTCCTAACGACCTTAGTTTTTACTGTACATTATTACCCTAATCTTCTGCTAAATATCGTTTTCTGTAGCTTCAGC
ATTATCTTATTATTGCTCCAAAGTCGTGATTTCAACCGCAGCAGTGCAACCGCAGCGGGGATTGTCTCTGTGATTAGTTT
TGTCATTCTAATCATCTACTCGACATACGGCAGCTTGTATTTTGGTGACGGGTTTTCGCCCAAAATAACCGACTTGAGTA
TGGCATTTTATTTTTCCATGGTAACCATGACCACTGTTGGTTATGGCGATATCCTACCCGTGACTGAGACCGCAAGACTT
TTTACTATTTCGATGATTATTGCCGGAATTGCAGTATTTGCCACATCCGTAAGCACTATTTTTGGGCCTTTCATTAGAGA
TGGTTTAAGCAAACTTATACAGGGAAAAAAGCACACTATGAAAAGAGCCGATCACTTTATTGTTTGTGGTACTTCCGCCA
TGGCGACAAATACCATTATTAAACTGCATCAGCGCGGATTAGCCGTCACAATTATCACGGTAAGACCCAGTGATGAGTTT
GAAATAATTGAGCAAAGTCTGGAGGGGAAATTTGATATTATCTCCGGCGACAGCAGCGATACCGCCGTGCTAAAACAGGC
TGGTTTAGAGCAGTGCCGTGCTATTTTAGCGCTAACGGATAATGATGCTGATAATGCCTTTATCGTATTATCGGCTAAAG
ATTTAAGCGCTAATGCTAAAACAGTCATCATAGTCAACGACAGTAAGAATTTATCTAAAATTCAGAGGGTTCAACCTGAT
GTTTTATTGTCACCACAACTGTTTGGTAGTGAAGTACTGGCACGCATGCTAAATGGTGAAGCGATGGATAATAATGATTT
AGCAGAACTGTTACTCAATTCAGCTCACGGCATACCATCAAAAAATGATTTGTAG

Upstream 100 bases:

>100_bases
GCGTCATAAAAGTCTGCTGATATGGCAGCATCAGCGTTACAAGCTCAGTGCTATCACTGTACTACTTAATAGCTTGTTGA
TATTTAAAACTGTTTACGGA

Downstream 100 bases:

>100_bases
CTCTCAGACAAAATCTTAGAACAAGCAATTTATTGTTGATAAAGCCTCTGTCTCGGCGTTACCCATTAAACATACGCCTT
GAAAATAACCCCAAGTTGAC

Product: voltage-gated potassium channel

Products: K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 364; Mature: 363

Protein sequence:

>364_residues
MSAQVFSPKQIPHLADINFTVLTNAPWFMLGVFLLLNSIGLLFRARIAWVMSLVLLLTTLVFTVHYYPNLLLNIVFCSFS
IILLLLQSRDFNRSSATAAGIVSVISFVILIIYSTYGSLYFGDGFSPKITDLSMAFYFSMVTMTTVGYGDILPVTETARL
FTISMIIAGIAVFATSVSTIFGPFIRDGLSKLIQGKKHTMKRADHFIVCGTSAMATNTIIKLHQRGLAVTIITVRPSDEF
EIIEQSLEGKFDIISGDSSDTAVLKQAGLEQCRAILALTDNDADNAFIVLSAKDLSANAKTVIIVNDSKNLSKIQRVQPD
VLLSPQLFGSEVLARMLNGEAMDNNDLAELLLNSAHGIPSKNDL

Sequences:

>Translated_364_residues
MSAQVFSPKQIPHLADINFTVLTNAPWFMLGVFLLLNSIGLLFRARIAWVMSLVLLLTTLVFTVHYYPNLLLNIVFCSFS
IILLLLQSRDFNRSSATAAGIVSVISFVILIIYSTYGSLYFGDGFSPKITDLSMAFYFSMVTMTTVGYGDILPVTETARL
FTISMIIAGIAVFATSVSTIFGPFIRDGLSKLIQGKKHTMKRADHFIVCGTSAMATNTIIKLHQRGLAVTIITVRPSDEF
EIIEQSLEGKFDIISGDSSDTAVLKQAGLEQCRAILALTDNDADNAFIVLSAKDLSANAKTVIIVNDSKNLSKIQRVQPD
VLLSPQLFGSEVLARMLNGEAMDNNDLAELLLNSAHGIPSKNDL
>Mature_363_residues
SAQVFSPKQIPHLADINFTVLTNAPWFMLGVFLLLNSIGLLFRARIAWVMSLVLLLTTLVFTVHYYPNLLLNIVFCSFSI
ILLLLQSRDFNRSSATAAGIVSVISFVILIIYSTYGSLYFGDGFSPKITDLSMAFYFSMVTMTTVGYGDILPVTETARLF
TISMIIAGIAVFATSVSTIFGPFIRDGLSKLIQGKKHTMKRADHFIVCGTSAMATNTIIKLHQRGLAVTIITVRPSDEFE
IIEQSLEGKFDIISGDSSDTAVLKQAGLEQCRAILALTDNDADNAFIVLSAKDLSANAKTVIIVNDSKNLSKIQRVQPDV
LLSPQLFGSEVLARMLNGEAMDNNDLAELLLNSAHGIPSKNDL

Specific function: May play a role in the defense against osmotic shock [H]

COG id: COG1226

COG function: function code P; Kef-type K+ transport systems, predicted NAD-binding component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RCK N-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1787503, Length=363, Percent_Identity=58.1267217630854, Blast_Score=432, Evalue=1e-122,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013099
- InterPro:   IPR016040
- InterPro:   IPR003148 [H]

Pfam domain/function: PF07885 Ion_trans_2; PF02254 TrkA_N [H]

EC number: NA

Molecular weight: Translated: 39775; Mature: 39644

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAQVFSPKQIPHLADINFTVLTNAPWFMLGVFLLLNSIGLLFRARIAWVMSLVLLLTTL
CCCCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VFTVHYYPNLLLNIVFCSFSIILLLLQSRDFNRSSATAAGIVSVISFVILIIYSTYGSLY
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEE
FGDGFSPKITDLSMAFYFSMVTMTTVGYGDILPVTETARLFTISMIIAGIAVFATSVSTI
ECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
FGPFIRDGLSKLIQGKKHTMKRADHFIVCGTSAMATNTIIKLHQRGLAVTIITVRPSDEF
HHHHHHHHHHHHHCCHHHHHHHCCEEEEECCHHHHHHHHHHHHCCCEEEEEEEECCCCHH
EIIEQSLEGKFDIISGDSSDTAVLKQAGLEQCRAILALTDNDADNAFIVLSAKDLSANAK
HHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHEEEEEECCCCCCEEEEEEECCCCCCCC
TVIIVNDSKNLSKIQRVQPDVLLSPQLFGSEVLARMLNGEAMDNNDLAELLLNSAHGIPS
EEEEEECCCCHHHHHHCCCCCEECCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCC
KNDL
CCCC
>Mature Secondary Structure 
SAQVFSPKQIPHLADINFTVLTNAPWFMLGVFLLLNSIGLLFRARIAWVMSLVLLLTTL
CCCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VFTVHYYPNLLLNIVFCSFSIILLLLQSRDFNRSSATAAGIVSVISFVILIIYSTYGSLY
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEE
FGDGFSPKITDLSMAFYFSMVTMTTVGYGDILPVTETARLFTISMIIAGIAVFATSVSTI
ECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
FGPFIRDGLSKLIQGKKHTMKRADHFIVCGTSAMATNTIIKLHQRGLAVTIITVRPSDEF
HHHHHHHHHHHHHCCHHHHHHHCCEEEEECCHHHHHHHHHHHHCCCEEEEEEEECCCCHH
EIIEQSLEGKFDIISGDSSDTAVLKQAGLEQCRAILALTDNDADNAFIVLSAKDLSANAK
HHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHEEEEEECCCCCCEEEEEEECCCCCCCC
TVIIVNDSKNLSKIQRVQPDVLLSPQLFGSEVLARMLNGEAMDNNDLAELLLNSAHGIPS
EEEEEECCCCHHHHHHCCCCCEECCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCC
KNDL
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: K (I) [Periplasm] [C]

Specific reaction: K (I) [Periplasm] = K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8170937; 9097039; 9278503 [H]