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The map label for this gene is mtnN [H]

Identifier: 167623563

GI number: 167623563

Start: 1958860

End: 1959645

Strand: Reverse

Name: mtnN [H]

Synonym: Shal_1632

Alternate gene names: 167623563

Gene position: 1959645-1958860 (Counterclockwise)

Preceding gene: 167623564

Following gene: 167623562

Centisome position: 37.49

GC content: 46.44

Gene sequence:

>786_bases
ATGCGCACCGCTCTTGTCATTATCACTCTACTATCATCACTTATGACTATTAATACTCAAGCAAAACCTGCAGATACTGC
AGCTAGATCTCAGCCAATCGCAATTTTAGGTGCGATGGATGCTGAAATTGAAAAGCTACTACCTGAAATCACACAACGCC
AAACTCATACAGTTGCTAAAAATACTTATTACACAGGCTTTATCGAAGGCAAACCTGTTGTTGTTACCCGCTCAGGTGTG
GGTAAAGTTAATGCCGCCATCACCACTTACGTGTTGATTAACCAGTTTGATGTAAACAGTATTATCTTTACGGGTATCGC
TGGCGCGGCAGGTCCTAAACTGAATGTTGCCGATGTGGTGATTTCGACTGCACTAGTACAACACGATGTAGACTTAACCG
CTTTTGGCGCGCCAAAAGGTCAGCTTGATGGTTATGATGATCGCTACTTCTACGCTGATGAAAAGTTACAAGCTCTAGCG
CTAGAAGCGGCGAAAGGAGCGGTCGGCGAAGCGCGCGTACACTCGGGCATTATCGCAACGGGCGATCAGTTTATAGCCGA
TAAAGGCATAGTCAGCATGCTACTTCAAGAGTTCAATGCTATCGCCGTAGAGATGGAAGGCGCTGCAGTGGCGCAGGTCA
CCGATATGTTTGATATTCCATTGGTTGTCATTCGCACCATCTCTGATAAAGCCGATGGCTCGGCGCATCTTGTCTATGAA
GAGGCTAAGCAGGTAACCGCCGACAACTCAGTGGCCATCACACTAAATATGATCCGCGAAATGTAA

Upstream 100 bases:

>100_bases
GGTGACTTCACGTTAGAATAAAATAGCTAAAAAGCACGTTTACTCTCACAACAGGTCTCATTATGATGCGCGCATCTCAA
CTCTATGGAAGGCCGCTAAG

Downstream 100 bases:

>100_bases
TGAATAAAGTTTGAATTCGCTTCTAGATTAAAAAGGCGCTAAACCTGATGGTTTAGCGCCTTTTTAATCTGGCCTCGGCT
AGCCTTGAATAAACCACTAT

Product: purine phosphorylase family 1

Products: NA

Alternate protein names: MTA/SAH nucleosidase; MTAN; 5'-methylthioadenosine nucleosidase; MTA nucleosidase; S-adenosylhomocysteine nucleosidase; AdoHcy nucleosidase; SAH nucleosidase; SRH nucleosidase [H]

Number of amino acids: Translated: 261; Mature: 261

Protein sequence:

>261_residues
MRTALVIITLLSSLMTINTQAKPADTAARSQPIAILGAMDAEIEKLLPEITQRQTHTVAKNTYYTGFIEGKPVVVTRSGV
GKVNAAITTYVLINQFDVNSIIFTGIAGAAGPKLNVADVVISTALVQHDVDLTAFGAPKGQLDGYDDRYFYADEKLQALA
LEAAKGAVGEARVHSGIIATGDQFIADKGIVSMLLQEFNAIAVEMEGAAVAQVTDMFDIPLVVIRTISDKADGSAHLVYE
EAKQVTADNSVAITLNMIREM

Sequences:

>Translated_261_residues
MRTALVIITLLSSLMTINTQAKPADTAARSQPIAILGAMDAEIEKLLPEITQRQTHTVAKNTYYTGFIEGKPVVVTRSGV
GKVNAAITTYVLINQFDVNSIIFTGIAGAAGPKLNVADVVISTALVQHDVDLTAFGAPKGQLDGYDDRYFYADEKLQALA
LEAAKGAVGEARVHSGIIATGDQFIADKGIVSMLLQEFNAIAVEMEGAAVAQVTDMFDIPLVVIRTISDKADGSAHLVYE
EAKQVTADNSVAITLNMIREM
>Mature_261_residues
MRTALVIITLLSSLMTINTQAKPADTAARSQPIAILGAMDAEIEKLLPEITQRQTHTVAKNTYYTGFIEGKPVVVTRSGV
GKVNAAITTYVLINQFDVNSIIFTGIAGAAGPKLNVADVVISTALVQHDVDLTAFGAPKGQLDGYDDRYFYADEKLQALA
LEAAKGAVGEARVHSGIIATGDQFIADKGIVSMLLQEFNAIAVEMEGAAVAQVTDMFDIPLVVIRTISDKADGSAHLVYE
EAKQVTADNSVAITLNMIREM

Specific function: Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively [H]

COG id: COG0775

COG function: function code F; Nucleoside phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/UDP phosphorylase family. MtnN subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786354, Length=230, Percent_Identity=36.5217391304348, Blast_Score=124, Evalue=8e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010049
- InterPro:   IPR018017
- InterPro:   IPR000845 [H]

Pfam domain/function: PF01048 PNP_UDP_1 [H]

EC number: =3.2.2.9 [H]

Molecular weight: Translated: 27798; Mature: 27798

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTALVIITLLSSLMTINTQAKPADTAARSQPIAILGAMDAEIEKLLPEITQRQTHTVAK
CCHHHHHHHHHHHHHCCCCCCCCCCHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHC
NTYYTGFIEGKPVVVTRSGVGKVNAAITTYVLINQFDVNSIIFTGIAGAAGPKLNVADVV
CCEEEEEECCCEEEEECCCCCCCHHHEEEEEEEEECCCCCEEEECCCCCCCCCCCHHHHH
ISTALVQHDVDLTAFGAPKGQLDGYDDRYFYADEKLQALALEAAKGAVGEARVHSGIIAT
HHHHHHHCCCCEEEECCCCCCCCCCCCCEEECCCHHHHHHHHHHCCCCCHHHHHCCEEEC
GDQFIADKGIVSMLLQEFNAIAVEMEGAAVAQVTDMFDIPLVVIRTISDKADGSAHLVYE
CCHHHHHHHHHHHHHHHCCEEEEEECCCCEEHHHHHHCCCEEEEEECCCCCCCCEEEEEH
EAKQVTADNSVAITLNMIREM
HHHHHCCCCCEEEEEEEHHCC
>Mature Secondary Structure
MRTALVIITLLSSLMTINTQAKPADTAARSQPIAILGAMDAEIEKLLPEITQRQTHTVAK
CCHHHHHHHHHHHHHCCCCCCCCCCHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHC
NTYYTGFIEGKPVVVTRSGVGKVNAAITTYVLINQFDVNSIIFTGIAGAAGPKLNVADVV
CCEEEEEECCCEEEEECCCCCCCHHHEEEEEEEEECCCCCEEEECCCCCCCCCCCHHHHH
ISTALVQHDVDLTAFGAPKGQLDGYDDRYFYADEKLQALALEAAKGAVGEARVHSGIIAT
HHHHHHHCCCCEEEECCCCCCCCCCCCCEEECCCHHHHHHHHHHCCCCCHHHHHCCEEEC
GDQFIADKGIVSMLLQEFNAIAVEMEGAAVAQVTDMFDIPLVVIRTISDKADGSAHLVYE
CCHHHHHHHHHHHHHHHCCEEEEEECCCCEEHHHHHHCCCEEEEEECCCCCCCCEEEEEH
EAKQVTADNSVAITLNMIREM
HHHHHCCCCCEEEEEEEHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA