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The map label for this gene is atoS [H]

Identifier: 167623376

GI number: 167623376

Start: 1742467

End: 1743591

Strand: Direct

Name: atoS [H]

Synonym: Shal_1445

Alternate gene names: 167623376

Gene position: 1742467-1743591 (Clockwise)

Preceding gene: 167623375

Following gene: 167623377

Centisome position: 33.34

GC content: 47.38

Gene sequence:

>1125_bases
ATGTCCGCTATTCTGAAGCCACAACTCGATACAACTGATGTAACTAACGTCACTGATGCAACTCATGCAAGTGTGGCGAA
GCGTCCACAGTTGGTTGATGTTCAGCAAGCCGCGAATATGTCTAATCGTATGGAGCATATCCTCCAAGCCATGCCCTCAG
GAGTCGTGATCATCAATGGCGATGGTATTGTTACCGAAGCGAACCCAGTCGCAATTGAACTTTTAGGCACTCCTTTAGAA
GGGCAGCGTTGGTTGCAAATTATCAATCGGGCGTTTTCGCCACAAGATGATGATGGCCATGAAGTGTCACTGCGTAACGG
TCGTCGAGTTAAGCTCGCTATTACGCCGTTGACGCCAGAGCCCGGTCAGCTAATTGTATTAACCGATCTAACTGAAACTC
GACTACTGCAAAAGAACTTGTCGCACCTGCAAAGGTTGTCGGCACTGGGTAAAATGGTGGCAACACTTGCGCACCAAGTC
AGAACGCCGTTGAGTGCAGCGCTATTGTATGCCTCTAACCTTGCAAGCCCGAGAATATCCGATGACGCTAGAAAACGTTT
TCAAGGCAAGCTAGTCGATAGACTCAATGAATTAGAGCATCAGGTTAACGATATGCTGTTAATGGCCAAAGGTCGCCAGC
AGGAGCTCGATACTATCTTACAGATCGATGAAGTGGTTGATAATGTGCTGAGTAACTGCCAACCGATAGCGGAGCAGAAA
AACTGCAGGCTGGTCTTTAATAATGAGTCCAAACAGAAGATCCGCGCCAATGATGCCGCGCTTTGTTCGGCGATAAATAA
TTTAGTCATGAACAGCATCGAAGCCGGTGCAAACCAAATCACTCTGCGTGCATTCGATACTCAAACAGCGCTGCATCTCG
ATGTGATTGACAATGGCAAGGGACTCGATGCCGCTATGCAGAAAAAGGTTCTTGAGCCATTTTTTACCACTAAGTCACAA
GGTACAGGTCTTGGCCTCGCGGTCGTGCAATCGGTTGTCAATAACCACGGTGGAATGATGCAGTTCAGTTGTCATCCAGG
TAATGGCTGCACTGCGTCATTGAAGTTCCCATTGATCACGGCCATTAATAATAAAGAAGTGCTTGGAGATAATCAGCATG
TCTGA

Upstream 100 bases:

>100_bases
GCAGTCACGTCCTAGCAGCGCAGCGTCCTTCTTAGAACTAAACAACTGGCACAAATCCTGCTTTAACCCGTTCAAATGCA
GTTTTTTTGACGGGGTCACC

Downstream 100 bases:

>100_bases
AGGTAAGTTATTGCTTGTAGAAGATGACGCCTCACTGCGCGAGGCGCTGCTCGATACCTTGATGCTAGCGCATTATGATT
GCGTCGATGTAGGCTCTGCT

Product: PAS/PAC sensor-containing signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 374; Mature: 373

Protein sequence:

>374_residues
MSAILKPQLDTTDVTNVTDATHASVAKRPQLVDVQQAANMSNRMEHILQAMPSGVVIINGDGIVTEANPVAIELLGTPLE
GQRWLQIINRAFSPQDDDGHEVSLRNGRRVKLAITPLTPEPGQLIVLTDLTETRLLQKNLSHLQRLSALGKMVATLAHQV
RTPLSAALLYASNLASPRISDDARKRFQGKLVDRLNELEHQVNDMLLMAKGRQQELDTILQIDEVVDNVLSNCQPIAEQK
NCRLVFNNESKQKIRANDAALCSAINNLVMNSIEAGANQITLRAFDTQTALHLDVIDNGKGLDAAMQKKVLEPFFTTKSQ
GTGLGLAVVQSVVNNHGGMMQFSCHPGNGCTASLKFPLITAINNKEVLGDNQHV

Sequences:

>Translated_374_residues
MSAILKPQLDTTDVTNVTDATHASVAKRPQLVDVQQAANMSNRMEHILQAMPSGVVIINGDGIVTEANPVAIELLGTPLE
GQRWLQIINRAFSPQDDDGHEVSLRNGRRVKLAITPLTPEPGQLIVLTDLTETRLLQKNLSHLQRLSALGKMVATLAHQV
RTPLSAALLYASNLASPRISDDARKRFQGKLVDRLNELEHQVNDMLLMAKGRQQELDTILQIDEVVDNVLSNCQPIAEQK
NCRLVFNNESKQKIRANDAALCSAINNLVMNSIEAGANQITLRAFDTQTALHLDVIDNGKGLDAAMQKKVLEPFFTTKSQ
GTGLGLAVVQSVVNNHGGMMQFSCHPGNGCTASLKFPLITAINNKEVLGDNQHV
>Mature_373_residues
SAILKPQLDTTDVTNVTDATHASVAKRPQLVDVQQAANMSNRMEHILQAMPSGVVIINGDGIVTEANPVAIELLGTPLEG
QRWLQIINRAFSPQDDDGHEVSLRNGRRVKLAITPLTPEPGQLIVLTDLTETRLLQKNLSHLQRLSALGKMVATLAHQVR
TPLSAALLYASNLASPRISDDARKRFQGKLVDRLNELEHQVNDMLLMAKGRQQELDTILQIDEVVDNVLSNCQPIAEQKN
CRLVFNNESKQKIRANDAALCSAINNLVMNSIEAGANQITLRAFDTQTALHLDVIDNGKGLDAAMQKKVLEPFFTTKSQG
TGLGLAVVQSVVNNHGGMMQFSCHPGNGCTASLKFPLITAINNKEVLGDNQHV

Specific function: Member of the two-component regulatory system AtoS/AtoC; may activate AtoC by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=339, Percent_Identity=28.023598820059, Blast_Score=121, Evalue=6e-29,
Organism=Escherichia coli, GI1790436, Length=236, Percent_Identity=31.3559322033898, Blast_Score=106, Evalue=3e-24,
Organism=Escherichia coli, GI1790346, Length=222, Percent_Identity=24.7747747747748, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1790300, Length=241, Percent_Identity=25.3112033195021, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1786600, Length=343, Percent_Identity=22.4489795918367, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788713, Length=253, Percent_Identity=24.5059288537549, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 40770; Mature: 40639

Theoretical pI: Translated: 6.85; Mature: 6.85

Prosite motif: PS50112 PAS ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAILKPQLDTTDVTNVTDATHASVAKRPQLVDVQQAANMSNRMEHILQAMPSGVVIING
CCCCCCCCCCCCCCCCCCCHHHHHHHCCCCEECHHHHHCHHHHHHHHHHHCCCCEEEECC
DGIVTEANPVAIELLGTPLEGQRWLQIINRAFSPQDDDGHEVSLRNGRRVKLAITPLTPE
CEEEECCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCEEEECCCCEEEEEEECCCCC
PGQLIVLTDLTETRLLQKNLSHLQRLSALGKMVATLAHQVRTPLSAALLYASNLASPRIS
CCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCC
DDARKRFQGKLVDRLNELEHQVNDMLLMAKGRQQELDTILQIDEVVDNVLSNCQPIAEQK
HHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCHHCCC
NCRLVFNNESKQKIRANDAALCSAINNLVMNSIEAGANQITLRAFDTQTALHLDVIDNGK
CCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCEEEEEEEECCCC
GLDAAMQKKVLEPFFTTKSQGTGLGLAVVQSVVNNHGGMMQFSCHPGNGCTASLKFPLIT
CCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCEEEEECEEEE
AINNKEVLGDNQHV
EECCCCCCCCCCCC
>Mature Secondary Structure 
SAILKPQLDTTDVTNVTDATHASVAKRPQLVDVQQAANMSNRMEHILQAMPSGVVIING
CCCCCCCCCCCCCCCCCCHHHHHHHCCCCEECHHHHHCHHHHHHHHHHHCCCCEEEECC
DGIVTEANPVAIELLGTPLEGQRWLQIINRAFSPQDDDGHEVSLRNGRRVKLAITPLTPE
CEEEECCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCEEEECCCCEEEEEEECCCCC
PGQLIVLTDLTETRLLQKNLSHLQRLSALGKMVATLAHQVRTPLSAALLYASNLASPRIS
CCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCC
DDARKRFQGKLVDRLNELEHQVNDMLLMAKGRQQELDTILQIDEVVDNVLSNCQPIAEQK
HHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCHHCCC
NCRLVFNNESKQKIRANDAALCSAINNLVMNSIEAGANQITLRAFDTQTALHLDVIDNGK
CCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCEEEEEEEECCCC
GLDAAMQKKVLEPFFTTKSQGTGLGLAVVQSVVNNHGGMMQFSCHPGNGCTASLKFPLIT
CCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCEEEEECEEEE
AINNKEVLGDNQHV
EECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8346225; 9097040; 9278503 [H]