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The map label for this gene is ntrC [H]

Identifier: 167623375

GI number: 167623375

Start: 1740519

End: 1741952

Strand: Direct

Name: ntrC [H]

Synonym: Shal_1444

Alternate gene names: 167623375

Gene position: 1740519-1741952 (Clockwise)

Preceding gene: 167623374

Following gene: 167623376

Centisome position: 33.3

GC content: 45.05

Gene sequence:

>1434_bases
ATGATGCAAACAGATCAACGAATTCTACTTGTCGGTAACCAGTCTGAGCGAATTAATCGCTTGTCGTGTGTATTTGAGTT
TTTAGGTGAGCAGGTTGAGTTAATCGATTTCGATAAACTTGAACTACACACTAAACAGACTCGCTTTCGCGCGATTGTTT
TACCGTCTGAGAACCAACCTAAAGAACTTATTCAGTCTTTAACTGGTATGCTTCCATGGCAACCTTTTTTGACGCTAGGG
GAAAGAGACGACATTAAAGCGTCGAATATTCTCGGCTGCATCGAAGAGCCACTGAACTACCCTCAATTAACTGAACTGCT
GCATTTTTGTCAGGTCTATGGACAAGTTAAACGTCCAGAGATCCCAACAAGTGCTAATCAGACTAAGTTGTTTAGAAGTT
TAGTCGGCCGCAGTGAGGGGATCGCCAGTGTCCGCCATCTGATTAATCAAGTTTCTGGCTCTGAAGCCACTGTTCTAGTA
CTTGGTCAATCGGGTACAGGTAAAGAGGTGGTTGCCCGTAATATTCACTATATCTCAGATCGCCGTGATGGCCCGTTTAT
TCCGGTCAACTGCGGTGCGATCCCGGCTGAGTTATTAGAAAGTGAACTTTTTGGCCACGAAAAAGGCTCATTTACTGGCG
CAATTAGCGCTCGTAAAGGTCGTTTCGAACTCGCCGAAAAAGGGACGCTATTTCTAGACGAGATTGGCGATATGCCTTTG
CAGATGCAGGTTAAACTACTGCGAGTTTTGCAAGAGCGTATGTTTGAGCGCGTAGGTGGAAGTAAATCTATTGCTGCCGA
TGTACGCGTTGTCGCTGCAACTCATCGAAATTTAGAAACGATGATTGAAGAGGGTGGCTTTAGAGAAGATCTTTATTACA
GATTGAATGTTTTCCCGATTGAAATGCCTGCTTTGTGTGAGCGAAAAGAAGATATTCCACTCTTGTTACAAGAGTTAGTG
AGTCGCGTTTATAACGAAGGTCGTGGTCGAGTTCGTTTCACTCAGCGGGCTATCGAGTCACTGAAAGAACATGCTTGGTC
CGGTAACGTGCGAGAGCTATCAAACCTAGTCGAGCGTTTAACCATCCTCTATCCAGGTGGGTTAGTCGATGTTAATGACC
TACCAATCAAGTATCGTCATATCGATGTACCTGAGTATTGCGTCGAAATCAGTGAAGAGCAGCAAGAGCGTGATGCCTTA
GCCTCTATCTTTAATGATGAAGAGCCTATCGAGATCCCTGAAACGCGATTCCCAAGTGAATTGCCACCTGAAGGGGTAAA
CTTGAAAGACTTACTGGCTGAACTTGAGATTGACATGATCAGGCAAGCTCTAGATCAGCAAGATAACGTCGTTGCTCGAG
CAGCAGAAATGCTTGGGATCCGCCGTACGACTCTGGTTGAGAAAATGCGTAAGTACGGCATGGGTAAAGATTGA

Upstream 100 bases:

>100_bases
CATATTATTGGATAACAACTGGCTTGAATACTTAGCTTGAGAAAAGCAACGAACACTAATAATTAATGCGCTGAAATATT
TGAGCCTAACGGCCTTTGGA

Downstream 100 bases:

>100_bases
AGCTAAGAAGGACGCCCTGCAGGCTGCTAGGGCGTTCGCAGGCTCACTTCGAGATCCTAGAGCGGACTTCGTCCTTCTAG
GGCGCTGCGCTTCTAAGTAT

Product: sigma-54 dependent trancsriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 477; Mature: 477

Protein sequence:

>477_residues
MMQTDQRILLVGNQSERINRLSCVFEFLGEQVELIDFDKLELHTKQTRFRAIVLPSENQPKELIQSLTGMLPWQPFLTLG
ERDDIKASNILGCIEEPLNYPQLTELLHFCQVYGQVKRPEIPTSANQTKLFRSLVGRSEGIASVRHLINQVSGSEATVLV
LGQSGTGKEVVARNIHYISDRRDGPFIPVNCGAIPAELLESELFGHEKGSFTGAISARKGRFELAEKGTLFLDEIGDMPL
QMQVKLLRVLQERMFERVGGSKSIAADVRVVAATHRNLETMIEEGGFREDLYYRLNVFPIEMPALCERKEDIPLLLQELV
SRVYNEGRGRVRFTQRAIESLKEHAWSGNVRELSNLVERLTILYPGGLVDVNDLPIKYRHIDVPEYCVEISEEQQERDAL
ASIFNDEEPIEIPETRFPSELPPEGVNLKDLLAELEIDMIRQALDQQDNVVARAAEMLGIRRTTLVEKMRKYGMGKD

Sequences:

>Translated_477_residues
MMQTDQRILLVGNQSERINRLSCVFEFLGEQVELIDFDKLELHTKQTRFRAIVLPSENQPKELIQSLTGMLPWQPFLTLG
ERDDIKASNILGCIEEPLNYPQLTELLHFCQVYGQVKRPEIPTSANQTKLFRSLVGRSEGIASVRHLINQVSGSEATVLV
LGQSGTGKEVVARNIHYISDRRDGPFIPVNCGAIPAELLESELFGHEKGSFTGAISARKGRFELAEKGTLFLDEIGDMPL
QMQVKLLRVLQERMFERVGGSKSIAADVRVVAATHRNLETMIEEGGFREDLYYRLNVFPIEMPALCERKEDIPLLLQELV
SRVYNEGRGRVRFTQRAIESLKEHAWSGNVRELSNLVERLTILYPGGLVDVNDLPIKYRHIDVPEYCVEISEEQQERDAL
ASIFNDEEPIEIPETRFPSELPPEGVNLKDLLAELEIDMIRQALDQQDNVVARAAEMLGIRRTTLVEKMRKYGMGKD
>Mature_477_residues
MMQTDQRILLVGNQSERINRLSCVFEFLGEQVELIDFDKLELHTKQTRFRAIVLPSENQPKELIQSLTGMLPWQPFLTLG
ERDDIKASNILGCIEEPLNYPQLTELLHFCQVYGQVKRPEIPTSANQTKLFRSLVGRSEGIASVRHLINQVSGSEATVLV
LGQSGTGKEVVARNIHYISDRRDGPFIPVNCGAIPAELLESELFGHEKGSFTGAISARKGRFELAEKGTLFLDEIGDMPL
QMQVKLLRVLQERMFERVGGSKSIAADVRVVAATHRNLETMIEEGGFREDLYYRLNVFPIEMPALCERKEDIPLLLQELV
SRVYNEGRGRVRFTQRAIESLKEHAWSGNVRELSNLVERLTILYPGGLVDVNDLPIKYRHIDVPEYCVEISEEQQERDAL
ASIFNDEEPIEIPETRFPSELPPEGVNLKDLLAELEIDMIRQALDQQDNVVARAAEMLGIRRTTLVEKMRKYGMGKD

Specific function: Member of the two-component regulatory system ntrB/ntrC involved in the activation of nitrogen assimilatory genes such as glnA. NtrC is phosphorylated by ntrB and interacts with sigma-54 [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI87082117, Length=355, Percent_Identity=41.6901408450704, Blast_Score=268, Evalue=5e-73,
Organism=Escherichia coli, GI1789087, Length=350, Percent_Identity=43.4285714285714, Blast_Score=268, Evalue=8e-73,
Organism=Escherichia coli, GI1788550, Length=326, Percent_Identity=43.8650306748466, Blast_Score=263, Evalue=1e-71,
Organism=Escherichia coli, GI1790437, Length=378, Percent_Identity=40.7407407407407, Blast_Score=249, Evalue=3e-67,
Organism=Escherichia coli, GI1790299, Length=344, Percent_Identity=41.5697674418605, Blast_Score=244, Evalue=6e-66,
Organism=Escherichia coli, GI1789233, Length=347, Percent_Identity=41.7867435158501, Blast_Score=239, Evalue=2e-64,
Organism=Escherichia coli, GI1788905, Length=323, Percent_Identity=41.7956656346749, Blast_Score=235, Evalue=4e-63,
Organism=Escherichia coli, GI87082152, Length=342, Percent_Identity=36.5497076023392, Blast_Score=206, Evalue=3e-54,
Organism=Escherichia coli, GI87081872, Length=342, Percent_Identity=35.0877192982456, Blast_Score=201, Evalue=7e-53,
Organism=Escherichia coli, GI1786524, Length=352, Percent_Identity=37.2159090909091, Blast_Score=194, Evalue=1e-50,
Organism=Escherichia coli, GI1787583, Length=355, Percent_Identity=31.830985915493, Blast_Score=170, Evalue=2e-43,
Organism=Escherichia coli, GI1789828, Length=228, Percent_Identity=36.4035087719298, Blast_Score=145, Evalue=8e-36,
Organism=Escherichia coli, GI87081858, Length=329, Percent_Identity=29.1793313069909, Blast_Score=140, Evalue=1e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR010114
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 54141; Mature: 54141

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMQTDQRILLVGNQSERINRLSCVFEFLGEQVELIDFDKLELHTKQTRFRAIVLPSENQP
CCCCCCEEEEECCCHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHCCEEEEEEECCCCCH
KELIQSLTGMLPWQPFLTLGERDDIKASNILGCIEEPLNYPQLTELLHFCQVYGQVKRPE
HHHHHHHHCCCCCCHHHCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCC
IPTSANQTKLFRSLVGRSEGIASVRHLINQVSGSEATVLVLGQSGTGKEVVARNIHYISD
CCCCCHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHCC
RRDGPFIPVNCGAIPAELLESELFGHEKGSFTGAISARKGRFELAEKGTLFLDEIGDMPL
CCCCCEEEEECCCCCHHHHHHHHHCCCCCCEEEEEECCCCCEEHHCCCCEEHHHHCCCCH
QMQVKLLRVLQERMFERVGGSKSIAADVRVVAATHRNLETMIEEGGFREDLYYRLNVFPI
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEE
EMPALCERKEDIPLLLQELVSRVYNEGRGRVRFTQRAIESLKEHAWSGNVRELSNLVERL
CCHHHHCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
TILYPGGLVDVNDLPIKYRHIDVPEYCVEISEEQQERDALASIFNDEEPIEIPETRFPSE
HHCCCCCEEECCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
LPPEGVNLKDLLAELEIDMIRQALDQQDNVVARAAEMLGIRRTTLVEKMRKYGMGKD
CCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MMQTDQRILLVGNQSERINRLSCVFEFLGEQVELIDFDKLELHTKQTRFRAIVLPSENQP
CCCCCCEEEEECCCHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHCCEEEEEEECCCCCH
KELIQSLTGMLPWQPFLTLGERDDIKASNILGCIEEPLNYPQLTELLHFCQVYGQVKRPE
HHHHHHHHCCCCCCHHHCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCC
IPTSANQTKLFRSLVGRSEGIASVRHLINQVSGSEATVLVLGQSGTGKEVVARNIHYISD
CCCCCHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHCC
RRDGPFIPVNCGAIPAELLESELFGHEKGSFTGAISARKGRFELAEKGTLFLDEIGDMPL
CCCCCEEEEECCCCCHHHHHHHHHCCCCCCEEEEEECCCCCEEHHCCCCEEHHHHCCCCH
QMQVKLLRVLQERMFERVGGSKSIAADVRVVAATHRNLETMIEEGGFREDLYYRLNVFPI
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEE
EMPALCERKEDIPLLLQELVSRVYNEGRGRVRFTQRAIESLKEHAWSGNVRELSNLVERL
CCHHHHCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
TILYPGGLVDVNDLPIKYRHIDVPEYCVEISEEQQERDALASIFNDEEPIEIPETRFPSE
HHCCCCCEEECCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
LPPEGVNLKDLLAELEIDMIRQALDQQDNVVARAAEMLGIRRTTLVEKMRKYGMGKD
CCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2881918; 11481430; 8478331 [H]