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The map label for this gene is hlyB [H]

Identifier: 167623228

GI number: 167623228

Start: 1576102

End: 1577742

Strand: Direct

Name: hlyB [H]

Synonym: Shal_1295

Alternate gene names: 167623228

Gene position: 1576102-1577742 (Clockwise)

Preceding gene: 167623227

Following gene: 167623229

Centisome position: 30.15

GC content: 32.85

Gene sequence:

>1641_bases
ATGCAGAGTGTCAAGTTTAAATTGAGGTTAATGGTTTTTTTGTCATTATTCACTTTAACTACAGTAGGTATTTTTTCAGT
GTACAGTATGAAAAAATCAGCTGAAAGTATTCAGCTCCTGTATGATGTGAATATAAAAAGTATCAACATATCTAGTGAAG
TCATAGAGTTAATTGGTGTTGCTAGAAGTTCATTGTTGTTATCATTTCAACATGATCCAGCAAATGTGTTCTCATCATTA
CATGACCACCCAATATCAAGCCATTTAGATTTAATTTCAGATTCTTTGAATCGAATCGATGATTTGGTTGAGCTCTTGAA
AAATAACAACCTAAGTGATGTGCAGTCTGGAATGATTAATGATCTAATGACTAATCTTCATAAGTTGAATGAAAGTGGAT
TTAAACTAGCTGTGAATGAAATTATTGGAGGTGATTATTATGCTGCAAATGAGTTGTTAATCAAATATATTAATATGGAG
TCTGAAATTGTTACGGGAATAGCAAAGTCATTCCACTCATCAATTTTAAAAGATTCAGAGTATTTGTACAATATGACTGA
ACAACGTATTTGGAATAGTGTCTATGTTGTTTTGTTCAGTTTTTTTATTGGGATTGTATTGATCTATAGCCTATCAAGAT
TAATTACTGGGCGAGTAAACAGTGCATTGGAAGGGATCTATGTAGTAACAAATAATGTTACTAAAGGAGATTTGACTCAA
AGAGTGATACTTAAGGGAGAAGATGAGTTTACAGAGATTTCAAATAATATAAATATGGTAGTTGAATCTTTTCAAAAAAT
AATTTTGGACATCAATAGGAATGCTATTCATCTTAATGAAACCGCTGAAGAGAGTTCTTTAGTAACTATGACAACAAAAC
AAAATGTAATTACTCAGCAAGATCAAATTCAAATGCTTGCAACGGCTATGCATGAATTTACTTGTACAGTACAAGAGGTT
GCTAATAGTACAGCTCAAGCTGCTGATTCTTCAATTATTGCTGGATTATCAGTGACTGAAGGAAAGGTTGTTGTTGAAGA
TACTATATCAATGATTTGTGATTTAAATATTGGAATTACAAAGACAAGTGAACTTATTACTGAACTTTCGATTAGAATAG
ATAAAATCGGGTCAGTATTAGAAGTTATTGGTAGTATTTCGGAACAAACAAATTTACTTGCTTTAAATGCAGCTATTGAA
GCTGCAAGGGCGGGAGAAGCAGGTAGGGGCTTTGCTGTAGTGGCTGACGAGGTCAGGACATTAGCAAACCGAACTCAGCA
ATCCACAGAAGTAATTAAGGCCGTAGTAACAGAGTTGCATGACTTTAGTAACGATTCAGTTAGCAATATGACTACAAGTT
TTAATCTAGCAAAAGAAACAGCAGATAAAGCAAGAATGGCTGGTATAGCATTGGAAAGAATTAGTGAAAGTGTAGAGCAA
ATTAATGCGATGAATATTCAGATTGCCTCTGCAACTGAGGAACAAACAGTTGTTACTCGTGAAATTGATATCAATGTAAA
TAGAATAAATGATATATCAAATGAAACTTCAGTAGGAGCAGAGAAAAGTAGTGCTATAACATTAGAACTGTCTGGGTTAA
TAGAAGTTATTAAAAAGAATGTTGAAAAGTTTAATTGCTGA

Upstream 100 bases:

>100_bases
ACAGTTAACTAATATACTTATATATGACGTTTGTTAAAAGTTTATTCTAATTCGTTTTTTATGAGTTTTACATGGTCAAT
GTTTATTAAAGGTAAATTTA

Downstream 100 bases:

>100_bases
TAACGCTGTTAGTATTGAAATAGCTAGAGGTTAATTCACAACTGTCGACAGTGTACTATAAAGTTATTGTTTAATGTTAA
CTGTTTAATTCTGAAGTTTT

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 546; Mature: 546

Protein sequence:

>546_residues
MQSVKFKLRLMVFLSLFTLTTVGIFSVYSMKKSAESIQLLYDVNIKSINISSEVIELIGVARSSLLLSFQHDPANVFSSL
HDHPISSHLDLISDSLNRIDDLVELLKNNNLSDVQSGMINDLMTNLHKLNESGFKLAVNEIIGGDYYAANELLIKYINME
SEIVTGIAKSFHSSILKDSEYLYNMTEQRIWNSVYVVLFSFFIGIVLIYSLSRLITGRVNSALEGIYVVTNNVTKGDLTQ
RVILKGEDEFTEISNNINMVVESFQKIILDINRNAIHLNETAEESSLVTMTTKQNVITQQDQIQMLATAMHEFTCTVQEV
ANSTAQAADSSIIAGLSVTEGKVVVEDTISMICDLNIGITKTSELITELSIRIDKIGSVLEVIGSISEQTNLLALNAAIE
AARAGEAGRGFAVVADEVRTLANRTQQSTEVIKAVVTELHDFSNDSVSNMTTSFNLAKETADKARMAGIALERISESVEQ
INAMNIQIASATEEQTVVTREIDINVNRINDISNETSVGAEKSSAITLELSGLIEVIKKNVEKFNC

Sequences:

>Translated_546_residues
MQSVKFKLRLMVFLSLFTLTTVGIFSVYSMKKSAESIQLLYDVNIKSINISSEVIELIGVARSSLLLSFQHDPANVFSSL
HDHPISSHLDLISDSLNRIDDLVELLKNNNLSDVQSGMINDLMTNLHKLNESGFKLAVNEIIGGDYYAANELLIKYINME
SEIVTGIAKSFHSSILKDSEYLYNMTEQRIWNSVYVVLFSFFIGIVLIYSLSRLITGRVNSALEGIYVVTNNVTKGDLTQ
RVILKGEDEFTEISNNINMVVESFQKIILDINRNAIHLNETAEESSLVTMTTKQNVITQQDQIQMLATAMHEFTCTVQEV
ANSTAQAADSSIIAGLSVTEGKVVVEDTISMICDLNIGITKTSELITELSIRIDKIGSVLEVIGSISEQTNLLALNAAIE
AARAGEAGRGFAVVADEVRTLANRTQQSTEVIKAVVTELHDFSNDSVSNMTTSFNLAKETADKARMAGIALERISESVEQ
INAMNIQIASATEEQTVVTREIDINVNRINDISNETSVGAEKSSAITLELSGLIEVIKKNVEKFNC
>Mature_546_residues
MQSVKFKLRLMVFLSLFTLTTVGIFSVYSMKKSAESIQLLYDVNIKSINISSEVIELIGVARSSLLLSFQHDPANVFSSL
HDHPISSHLDLISDSLNRIDDLVELLKNNNLSDVQSGMINDLMTNLHKLNESGFKLAVNEIIGGDYYAANELLIKYINME
SEIVTGIAKSFHSSILKDSEYLYNMTEQRIWNSVYVVLFSFFIGIVLIYSLSRLITGRVNSALEGIYVVTNNVTKGDLTQ
RVILKGEDEFTEISNNINMVVESFQKIILDINRNAIHLNETAEESSLVTMTTKQNVITQQDQIQMLATAMHEFTCTVQEV
ANSTAQAADSSIIAGLSVTEGKVVVEDTISMICDLNIGITKTSELITELSIRIDKIGSVLEVIGSISEQTNLLALNAAIE
AARAGEAGRGFAVVADEVRTLANRTQQSTEVIKAVVTELHDFSNDSVSNMTTSFNLAKETADKARMAGIALERISESVEQ
INAMNIQIASATEEQTVVTREIDINVNRINDISNETSVGAEKSSAITLELSGLIEVIKKNVEKFNC

Specific function: May form a pore through which the hemolysin can be exported [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=399, Percent_Identity=26.0651629072682, Blast_Score=104, Evalue=2e-23,
Organism=Escherichia coli, GI2367378, Length=328, Percent_Identity=27.7439024390244, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1788194, Length=318, Percent_Identity=26.7295597484277, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1788195, Length=311, Percent_Identity=28.6173633440514, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI1789453, Length=224, Percent_Identity=33.4821428571429, Blast_Score=86, Evalue=8e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR000727 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 60089; Mature: 60089

Theoretical pI: Translated: 4.49; Mature: 4.49

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSVKFKLRLMVFLSLFTLTTVGIFSVYSMKKSAESIQLLYDVNIKSINISSEVIELIGV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHEEEEEECCEEEECCHHHHHHHHHH
ARSSLLLSFQHDPANVFSSLHDHPISSHLDLISDSLNRIDDLVELLKNNNLSDVQSGMIN
HHHHHEEEECCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
DLMTNLHKLNESGFKLAVNEIIGGDYYAANELLIKYINMESEIVTGIAKSFHSSILKDSE
HHHHHHHHHCCCCCEEEHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHH
YLYNMTEQRIWNSVYVVLFSFFIGIVLIYSLSRLITGRVNSALEGIYVVTNNVTKGDLTQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCCCCHHH
RVILKGEDEFTEISNNINMVVESFQKIILDINRNAIHLNETAEESSLVTMTTKQNVITQQ
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCEEEEEECCCHHCCH
DQIQMLATAMHEFTCTVQEVANSTAQAADSSIIAGLSVTEGKVVVEDTISMICDLNIGIT
HHHHHHHHHHHHHHHHHHHHHCHHHHHCCCHHEECEEECCCCEEHHHHHHHHHCCCCCCC
KTSELITELSIRIDKIGSVLEVIGSISEQTNLLALNAAIEAARAGEAGRGFAVVADEVRT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHCCCCCCCHHHHHHHHHH
LANRTQQSTEVIKAVVTELHDFSNDSVSNMTTSFNLAKETADKARMAGIALERISESVEQ
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
INAMNIQIASATEEQTVVTREIDINVNRINDISNETSVGAEKSSAITLELSGLIEVIKKN
HHHCEEEEECCCCCCEEEEEEEEEEHECCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHH
VEKFNC
HHHCCC
>Mature Secondary Structure
MQSVKFKLRLMVFLSLFTLTTVGIFSVYSMKKSAESIQLLYDVNIKSINISSEVIELIGV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHEEEEEECCEEEECCHHHHHHHHHH
ARSSLLLSFQHDPANVFSSLHDHPISSHLDLISDSLNRIDDLVELLKNNNLSDVQSGMIN
HHHHHEEEECCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
DLMTNLHKLNESGFKLAVNEIIGGDYYAANELLIKYINMESEIVTGIAKSFHSSILKDSE
HHHHHHHHHCCCCCEEEHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHH
YLYNMTEQRIWNSVYVVLFSFFIGIVLIYSLSRLITGRVNSALEGIYVVTNNVTKGDLTQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCCCCHHH
RVILKGEDEFTEISNNINMVVESFQKIILDINRNAIHLNETAEESSLVTMTTKQNVITQQ
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCEEEEEECCCHHCCH
DQIQMLATAMHEFTCTVQEVANSTAQAADSSIIAGLSVTEGKVVVEDTISMICDLNIGIT
HHHHHHHHHHHHHHHHHHHHHCHHHHHCCCHHEECEEECCCCEEHHHHHHHHHCCCCCCC
KTSELITELSIRIDKIGSVLEVIGSISEQTNLLALNAAIEAARAGEAGRGFAVVADEVRT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHCCCCCCCHHHHHHHHHH
LANRTQQSTEVIKAVVTELHDFSNDSVSNMTTSFNLAKETADKARMAGIALERISESVEQ
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
INAMNIQIASATEEQTVVTREIDINVNRINDISNETSVGAEKSSAITLELSGLIEVIKKN
HHHCEEEEECCCCCCEEEEEEEEEEHECCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHH
VEKFNC
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2162464; 10952301 [H]