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The map label for this gene is yibH [H]

Identifier: 167623184

GI number: 167623184

Start: 1524417

End: 1525559

Strand: Direct

Name: yibH [H]

Synonym: Shal_1250

Alternate gene names: 167623184

Gene position: 1524417-1525559 (Clockwise)

Preceding gene: 167623183

Following gene: 167623185

Centisome position: 29.16

GC content: 47.77

Gene sequence:

>1143_bases
ATGACGGAAGAAAAGGGTGTGAGTGCGAATGACGCCGCTAAAAATGAGCTCAGTAAAGAGGTCGAACAGGCTGAAAACCA
GAAAAACACAAAAATCCGTAAAGCGACTAATATCATATTAATCGTCGTCAGTTTTCTATTTGTATTTCACCTTATCGCTG
ACAGATTTATCCCATCAACGGACTTAGGCCGTATACGCGGCTATGTGGTACCTATTAGTCCGCAAGTGTCCGGCGAGATA
ATCGATATTTTAGTTGAACCCAACACCCTAATAAGGCAAGGCGATGTGCTTGCCAAAATTAATCCTCAAGATTATGAGAT
TGCGCTGCATCAAGCGGAGCAATCACTAAAAAAAGCCGGACAAAATGTCGGCGCCCAGACCGCCAATGTGACCGCCGCTC
AAGCAAAAGTGACCAATGCTGTGGCAAACCTTAAAAATGTACAGGTCCAGTCAAAGCGTATTTTTGCCATGGTCGATAAG
GCGGTTATGTCACAGGCTGATGGCGATAATGCGCGAGCCGAGCTGACAAAAGCTGAAGCTGGCGTAGCGAGTGCCAAAGC
CGATCTGGCGAAGGCGCAGGAGCGTTTAGGAGCGGAAGGGGAAAATAATACCAATGTTAAATCAGCGCTATTAAGTTTAG
AAACAGCCCAGATTAATCTAGCACGAACATCAATCACCGCACCAACCGATGGGGTTGCGTCAAACTTTAGGCTAAAAGAG
GGCATATACGCCAGTGCAGGCCAGCCTGTGATGACCTTTATCTCGTCTGAAGATGTGTGGATTGAGGCCTATTTTAGAGA
AAACAGCTTAGGCAATATGAAAGCGGGTGACAAAGTTGAGTTTGCCCTCGATTATGCTCCAGGAGAAGTCTTTAAAGCCA
AAGTAGGCAGTATCGATTACGGTATCGACTGGGGCCAGAGTGAGCAAACAGGCAAGCTGGCACAGGTGTCGGGTCAAACA
GGCTGGTTGCGTCAATCTCAGCGCTTCCCTGTGACGATCGTACTGCCTGCCGATGAAGCGGTGGGCCTAAGGCGTGTCGG
TGGGCAAGCCGATGTGATTGTCTACACCAGCGACAACAGTATTATAAATTTATTTGGTAAGTTCTGGATCCGCCTCGTGA
GCTGGTTCTCCTATGTCAGATAG

Upstream 100 bases:

>100_bases
AAAAAATAGTTCAGTGATTAGCGTGTCATTCGACACCAATATTGAGCGCTTGTACTAATGGCAATTAGATACAGGCTTAT
CGGCGACTTAAGGGATGACT

Downstream 100 bases:

>100_bases
TCATCTAACTGTGCACACAGATTCAAATACGGCAGTCAGTGTGACTGAAGAGGAGATATACACCCGTAGGGTATTGCGTT
TCACCCTTGGGATAGGCCTT

Product: secretion protein HlyD family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 380; Mature: 379

Protein sequence:

>380_residues
MTEEKGVSANDAAKNELSKEVEQAENQKNTKIRKATNIILIVVSFLFVFHLIADRFIPSTDLGRIRGYVVPISPQVSGEI
IDILVEPNTLIRQGDVLAKINPQDYEIALHQAEQSLKKAGQNVGAQTANVTAAQAKVTNAVANLKNVQVQSKRIFAMVDK
AVMSQADGDNARAELTKAEAGVASAKADLAKAQERLGAEGENNTNVKSALLSLETAQINLARTSITAPTDGVASNFRLKE
GIYASAGQPVMTFISSEDVWIEAYFRENSLGNMKAGDKVEFALDYAPGEVFKAKVGSIDYGIDWGQSEQTGKLAQVSGQT
GWLRQSQRFPVTIVLPADEAVGLRRVGGQADVIVYTSDNSIINLFGKFWIRLVSWFSYVR

Sequences:

>Translated_380_residues
MTEEKGVSANDAAKNELSKEVEQAENQKNTKIRKATNIILIVVSFLFVFHLIADRFIPSTDLGRIRGYVVPISPQVSGEI
IDILVEPNTLIRQGDVLAKINPQDYEIALHQAEQSLKKAGQNVGAQTANVTAAQAKVTNAVANLKNVQVQSKRIFAMVDK
AVMSQADGDNARAELTKAEAGVASAKADLAKAQERLGAEGENNTNVKSALLSLETAQINLARTSITAPTDGVASNFRLKE
GIYASAGQPVMTFISSEDVWIEAYFRENSLGNMKAGDKVEFALDYAPGEVFKAKVGSIDYGIDWGQSEQTGKLAQVSGQT
GWLRQSQRFPVTIVLPADEAVGLRRVGGQADVIVYTSDNSIINLFGKFWIRLVSWFSYVR
>Mature_379_residues
TEEKGVSANDAAKNELSKEVEQAENQKNTKIRKATNIILIVVSFLFVFHLIADRFIPSTDLGRIRGYVVPISPQVSGEII
DILVEPNTLIRQGDVLAKINPQDYEIALHQAEQSLKKAGQNVGAQTANVTAAQAKVTNAVANLKNVQVQSKRIFAMVDKA
VMSQADGDNARAELTKAEAGVASAKADLAKAQERLGAEGENNTNVKSALLSLETAQINLARTSITAPTDGVASNFRLKEG
IYASAGQPVMTFISSEDVWIEAYFRENSLGNMKAGDKVEFALDYAPGEVFKAKVGSIDYGIDWGQSEQTGKLAQVSGQTG
WLRQSQRFPVTIVLPADEAVGLRRVGGQADVIVYTSDNSIINLFGKFWIRLVSWFSYVR

Specific function: Unknown

COG id: COG1566

COG function: function code V; Multidrug resistance efflux pump

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1790024, Length=321, Percent_Identity=31.7757009345794, Blast_Score=128, Evalue=5e-31,
Organism=Escherichia coli, GI1790012, Length=323, Percent_Identity=30.6501547987616, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1790519, Length=308, Percent_Identity=30.8441558441558, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1789041, Length=305, Percent_Identity=24.5901639344262, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI87081951, Length=313, Percent_Identity=25.8785942492013, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1788711, Length=325, Percent_Identity=24.6153846153846, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1789637, Length=305, Percent_Identity=25.5737704918033, Blast_Score=80, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 41266; Mature: 41135

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEEKGVSANDAAKNELSKEVEQAENQKNTKIRKATNIILIVVSFLFVFHLIADRFIPST
CCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
DLGRIRGYVVPISPQVSGEIIDILVEPNTLIRQGDVLAKINPQDYEIALHQAEQSLKKAG
CCHHHCEEEEEECCCCCCEEEEEEECCCHHEECCCEEEEECCCCHHHHHHHHHHHHHHHH
QNVGAQTANVTAAQAKVTNAVANLKNVQVQSKRIFAMVDKAVMSQADGDNARAELTKAEA
HCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHC
GVASAKADLAKAQERLGAEGENNTNVKSALLSLETAQINLARTSITAPTDGVASNFRLKE
CHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHEEEEEEEEECCCCCCCCCCCEECC
GIYASAGQPVMTFISSEDVWIEAYFRENSLGNMKAGDKVEFALDYAPGEVFKAKVGSIDY
CCCCCCCCCEEEEECCCCEEEEEEEECCCCCCCCCCCEEEEEEECCCCHHHHHCCCCEEC
GIDWGQSEQTGKLAQVSGQTGWLRQSQRFPVTIVLPADEAVGLRRVGGQADVIVYTSDNS
CCCCCCCCCCCCEEEECCCCCHHCCCCCCCEEEEECCCCCCCHHHCCCCCCEEEEECCCC
IINLFGKFWIRLVSWFSYVR
HHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TEEKGVSANDAAKNELSKEVEQAENQKNTKIRKATNIILIVVSFLFVFHLIADRFIPST
CCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
DLGRIRGYVVPISPQVSGEIIDILVEPNTLIRQGDVLAKINPQDYEIALHQAEQSLKKAG
CCHHHCEEEEEECCCCCCEEEEEEECCCHHEECCCEEEEECCCCHHHHHHHHHHHHHHHH
QNVGAQTANVTAAQAKVTNAVANLKNVQVQSKRIFAMVDKAVMSQADGDNARAELTKAEA
HCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHC
GVASAKADLAKAQERLGAEGENNTNVKSALLSLETAQINLARTSITAPTDGVASNFRLKE
CHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHEEEEEEEEECCCCCCCCCCCEECC
GIYASAGQPVMTFISSEDVWIEAYFRENSLGNMKAGDKVEFALDYAPGEVFKAKVGSIDY
CCCCCCCCCEEEEECCCCEEEEEEEECCCCCCCCCCCEEEEEEECCCCHHHHHCCCCEEC
GIDWGQSEQTGKLAQVSGQTGWLRQSQRFPVTIVLPADEAVGLRRVGGQADVIVYTSDNS
CCCCCCCCCCCCEEEECCCCCHHCCCCCCCEEEEECCCCCCCHHHCCCCCCEEEEECCCC
IINLFGKFWIRLVSWFSYVR
HHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]