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The map label for this gene is thiL [H]

Identifier: 167623144

GI number: 167623144

Start: 1469348

End: 1470319

Strand: Direct

Name: thiL [H]

Synonym: Shal_1210

Alternate gene names: 167623144

Gene position: 1469348-1470319 (Clockwise)

Preceding gene: 167623143

Following gene: 167623145

Centisome position: 28.11

GC content: 47.84

Gene sequence:

>972_bases
GTGATTAGTATTGTGAAAGAATTTCAATTAATCGAAAGTTTCTTTACTGGGCGCGCCCAGTCTCGCAAAGACATTGCGGT
AGGTATTGGCGATGACTGCGCCATTGTTCAACCTGCTGAAAACAAGTGTATTGCTATCTCTTGTGACACCTTAGTTGAAA
ATGTGCACTTTTTCCCTGATATGCCAGCAAAGGAGCTGGGCATTAAGTCATTGGCAGTTAATCTGTCGGATCTTGCATCA
ATGGGTGCAGAGCCTGCATGGATGACTCTGGCACTGACTCTACCTGAAGTTGATGAAAGCTGGTTGGCTGACTTTAGCGC
AGGCTTGTTTGAGATTGCAGAGTACTACGGAGTGGCGCTTATTGGTGGTGACACCACGCGCGGCCCACGTTCAATCACTA
TCACGATTAATGGCCAGCTTCCGAAAGGTAAAGGCTTGACTCGTAGTGGTGCTAAAAACGGTGATTGGATCTATGTGACC
GGAACATTAGGCGACGCGGCACTTGGTTTAGACTTATTGCGTAATAAAGTTGAAGTGAGCAGCGAGGACCGGAGTTACCT
GATTAATCGTCACTACAGACCGACTCCAAGGGTACTGGCTGGCCAGTCACTGCGTACGATAGCGTCCAGCGCAATTGATA
TCTCAGACGGCCTTGTATCAGATATCCAACATGTCCTAAAAGCCTCGAATGTGGGGGCTGTGATTAATGTCGACAACATT
CCTATGTCTGAGCCATTGACGCGCAGCGTCTCAACTGAGTTAGCACTCAGTTACGCGCTGACAGGGGGCGAAGATTACGA
GTTACTGTTTACCGTACCCGAAGCGCAAAAAGGCATGCTAGAAATTTCCTTGGCAGAATCGGGAGTGAAATTTACCCAGA
TCGGTCAAGTGTGTACCGGTGGTCAGTTAAGATTAGTTGCCGGTAATCAGCCGTTCGAACCGGTCAACTTGGGCTTTGAG
CACTTTAATTAA

Upstream 100 bases:

>100_bases
GCATTTTCACTCAGAGCAAAGCCGCTGTAATTTCTTAATCTTTGCTAGAGTAACGGTCTGATCGACACTTATCTCATCTC
CCTGAACCTTCCTCTTATTT

Downstream 100 bases:

>100_bases
TGAATCTACTCTCTAAAGATCCAGTATTAGCTAAGCTATCACTGAAGAATCCTATTCACTTTCTCGCCCTTGGGTTTGGC
TCTGGGCTAGTGGCTAAGGC

Product: thiamine-monophosphate kinase

Products: NA

Alternate protein names: Thiamine-phosphate kinase [H]

Number of amino acids: Translated: 323; Mature: 323

Protein sequence:

>323_residues
MISIVKEFQLIESFFTGRAQSRKDIAVGIGDDCAIVQPAENKCIAISCDTLVENVHFFPDMPAKELGIKSLAVNLSDLAS
MGAEPAWMTLALTLPEVDESWLADFSAGLFEIAEYYGVALIGGDTTRGPRSITITINGQLPKGKGLTRSGAKNGDWIYVT
GTLGDAALGLDLLRNKVEVSSEDRSYLINRHYRPTPRVLAGQSLRTIASSAIDISDGLVSDIQHVLKASNVGAVINVDNI
PMSEPLTRSVSTELALSYALTGGEDYELLFTVPEAQKGMLEISLAESGVKFTQIGQVCTGGQLRLVAGNQPFEPVNLGFE
HFN

Sequences:

>Translated_323_residues
MISIVKEFQLIESFFTGRAQSRKDIAVGIGDDCAIVQPAENKCIAISCDTLVENVHFFPDMPAKELGIKSLAVNLSDLAS
MGAEPAWMTLALTLPEVDESWLADFSAGLFEIAEYYGVALIGGDTTRGPRSITITINGQLPKGKGLTRSGAKNGDWIYVT
GTLGDAALGLDLLRNKVEVSSEDRSYLINRHYRPTPRVLAGQSLRTIASSAIDISDGLVSDIQHVLKASNVGAVINVDNI
PMSEPLTRSVSTELALSYALTGGEDYELLFTVPEAQKGMLEISLAESGVKFTQIGQVCTGGQLRLVAGNQPFEPVNLGFE
HFN
>Mature_323_residues
MISIVKEFQLIESFFTGRAQSRKDIAVGIGDDCAIVQPAENKCIAISCDTLVENVHFFPDMPAKELGIKSLAVNLSDLAS
MGAEPAWMTLALTLPEVDESWLADFSAGLFEIAEYYGVALIGGDTTRGPRSITITINGQLPKGKGLTRSGAKNGDWIYVT
GTLGDAALGLDLLRNKVEVSSEDRSYLINRHYRPTPRVLAGQSLRTIASSAIDISDGLVSDIQHVLKASNVGAVINVDNI
PMSEPLTRSVSTELALSYALTGGEDYELLFTVPEAQKGMLEISLAESGVKFTQIGQVCTGGQLRLVAGNQPFEPVNLGFE
HFN

Specific function: Thiamine biosynthesis. [C]

COG id: COG0611

COG function: function code H; Thiamine monophosphate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiamine-monophosphate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786619, Length=320, Percent_Identity=54.375, Blast_Score=348, Evalue=2e-97,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR016188
- InterPro:   IPR006283 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: =2.7.4.16 [H]

Molecular weight: Translated: 34681; Mature: 34681

Theoretical pI: Translated: 4.48; Mature: 4.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISIVKEFQLIESFFTGRAQSRKDIAVGIGDDCAIVQPAENKCIAISCDTLVENVHFFPD
CCCHHHHHHHHHHHHCCCCCCCCCEEEEECCCCEEEECCCCCEEEEEHHHHHHHCCCCCC
MPAKELGIKSLAVNLSDLASMGAEPAWMTLALTLPEVDESWLADFSAGLFEIAEYYGVAL
CCHHHHCHHHEEECHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCEEE
IGGDTTRGPRSITITINGQLPKGKGLTRSGAKNGDWIYVTGTLGDAALGLDLLRNKVEVS
ECCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHCC
SEDRSYLINRHYRPTPRVLAGQSLRTIASSAIDISDGLVSDIQHVLKASNVGAVINVDNI
CCCCHHHCCCCCCCCCCHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCEEEEECCC
PMSEPLTRSVSTELALSYALTGGEDYELLFTVPEAQKGMLEISLAESGVKFTQIGQVCTG
CCCCCHHHHHHHHEEEEEEECCCCCEEEEEECCCCCCCEEEEEECCCCCEEEHHCCCCCC
GQLRLVAGNQPFEPVNLGFEHFN
CEEEEEECCCCCCCHHCCCCCCC
>Mature Secondary Structure
MISIVKEFQLIESFFTGRAQSRKDIAVGIGDDCAIVQPAENKCIAISCDTLVENVHFFPD
CCCHHHHHHHHHHHHCCCCCCCCCEEEEECCCCEEEECCCCCEEEEEHHHHHHHCCCCCC
MPAKELGIKSLAVNLSDLASMGAEPAWMTLALTLPEVDESWLADFSAGLFEIAEYYGVAL
CCHHHHCHHHEEECHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCEEE
IGGDTTRGPRSITITINGQLPKGKGLTRSGAKNGDWIYVTGTLGDAALGLDLLRNKVEVS
ECCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHCC
SEDRSYLINRHYRPTPRVLAGQSLRTIASSAIDISDGLVSDIQHVLKASNVGAVINVDNI
CCCCHHHCCCCCCCCCCHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCEEEEECCC
PMSEPLTRSVSTELALSYALTGGEDYELLFTVPEAQKGMLEISLAESGVKFTQIGQVCTG
CCCCCHHHHHHHHEEEEEEECCCCCEEEEEECCCCCCCEEEEEECCCCCEEEHHCCCCCC
GQLRLVAGNQPFEPVNLGFEHFN
CEEEEEECCCCCCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677609 [H]