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The map label for this gene is ribB [H]

Identifier: 167623141

GI number: 167623141

Start: 1467038

End: 1468141

Strand: Direct

Name: ribB [H]

Synonym: Shal_1207

Alternate gene names: 167623141

Gene position: 1467038-1468141 (Clockwise)

Preceding gene: 167623140

Following gene: 167623142

Centisome position: 28.07

GC content: 47.55

Gene sequence:

>1104_bases
ATGGCGTTACATAGTATAGAAGAGATCATTGAAGATATTCGTCTAGGTAAGATGGTGATCCTGATGGATGACGAAGACAG
AGAAAATGAAGGCGACCTTATCATGGCTGCCGACATGGTGACGCCTGAAGCTGTGAATTTCATGGCGACATTTGGCCGTG
GCCTTATCTGTCAAACATTGACTAAAGCGCGCTGTCAGCAGCTTAACTTACCTTTAATGGTAACTAACAATAACGCGCAG
TTCTCGACAAACTTTACCGTTTCGATTGAAGCGGCAGAGGGCGTAACAACGGGTATTTCAGCGCAAGACCGCGCTGTAAC
GGTACTCGCTGCCGTTGGCAAAGATGCTAAGCCATCAGATATCGTGCAACCTGGCCATATCTTCCCATTAATGGCACAAG
AAGGCGGCGTACTCATTCGCGCAGGCCATACTGAAGCCGGTTGTGATTTAGCACGCCTTGCAGGCTTTGAAGCATCGTCA
GTAATTGTTGAGATCCTAAATGATGACGGCACCATGGCTCGTCGCCCAGATCTTGAAATCTTCGCCCAGAAGCACGGTTT
GAAGATGGGCACGATTGCCGACCTTATCGAATACCGTAACACCAAAGAAACCAGCGTCGTTCGTGAAGCTAAATGTAAGT
TACCAACTCGCTTTGGTGAGTTCGACATGCTGACTTACCGCGATACAATCGACAACCAACTACATCATGTATTGGTTAAA
GGTGAAGTCACTGAAAACACCTTGGTACGTGTTCACCTGCAAAATACCTTTAATGACCTACTGCATTCTGAGCGCGATCA
GCAGCGTAGCTGGCCACTCGAAAAAGCCATGAAGCGTATTGGTGATGAAGGCGGCGTGTTGGTGTTATTAGGTAACCATG
AGCATAGCAGCGATATCTTAGCAAAAGTTAAAGCGTTTGAAGCTGAAGACAATGGCAGCACACCTGTTGCGGCGAAGTGG
CAGGGTACGTCTCGCCAAGTGGGTGTCGGCTCGCAAATTCTAGCAGATGTGGGCGTCACTAAGATGCGTCTACTGAGCTC
ACCAAAGCGCTATCACTCTCTTTCAGGCTTTGGTTTAGAAGTAACTGAATATATTGCAGAATAA

Upstream 100 bases:

>100_bases
ATAGAAACAAGAATAATCATTACATTAGCCACTATTTTTGAGAACATCGTTATTAGCGTATGTAACTTAGAATACAGTGA
TAAAAAATAAAGGTCTGAAC

Downstream 100 bases:

>100_bases
ATACTGGCCTCAGGTTGATTGTCAGCTTGAGGCTTAAATTCACACTTTTCTTATTAATTGCATAGAGATCAGCGCGGAGT
GCTGTGGTATCATACCGCCT

Product: 3,4-dihydroxy-2-butanone 4-phosphate synthase

Products: NA

Alternate protein names: DHBP synthase [H]

Number of amino acids: Translated: 367; Mature: 366

Protein sequence:

>367_residues
MALHSIEEIIEDIRLGKMVILMDDEDRENEGDLIMAADMVTPEAVNFMATFGRGLICQTLTKARCQQLNLPLMVTNNNAQ
FSTNFTVSIEAAEGVTTGISAQDRAVTVLAAVGKDAKPSDIVQPGHIFPLMAQEGGVLIRAGHTEAGCDLARLAGFEASS
VIVEILNDDGTMARRPDLEIFAQKHGLKMGTIADLIEYRNTKETSVVREAKCKLPTRFGEFDMLTYRDTIDNQLHHVLVK
GEVTENTLVRVHLQNTFNDLLHSERDQQRSWPLEKAMKRIGDEGGVLVLLGNHEHSSDILAKVKAFEAEDNGSTPVAAKW
QGTSRQVGVGSQILADVGVTKMRLLSSPKRYHSLSGFGLEVTEYIAE

Sequences:

>Translated_367_residues
MALHSIEEIIEDIRLGKMVILMDDEDRENEGDLIMAADMVTPEAVNFMATFGRGLICQTLTKARCQQLNLPLMVTNNNAQ
FSTNFTVSIEAAEGVTTGISAQDRAVTVLAAVGKDAKPSDIVQPGHIFPLMAQEGGVLIRAGHTEAGCDLARLAGFEASS
VIVEILNDDGTMARRPDLEIFAQKHGLKMGTIADLIEYRNTKETSVVREAKCKLPTRFGEFDMLTYRDTIDNQLHHVLVK
GEVTENTLVRVHLQNTFNDLLHSERDQQRSWPLEKAMKRIGDEGGVLVLLGNHEHSSDILAKVKAFEAEDNGSTPVAAKW
QGTSRQVGVGSQILADVGVTKMRLLSSPKRYHSLSGFGLEVTEYIAE
>Mature_366_residues
ALHSIEEIIEDIRLGKMVILMDDEDRENEGDLIMAADMVTPEAVNFMATFGRGLICQTLTKARCQQLNLPLMVTNNNAQF
STNFTVSIEAAEGVTTGISAQDRAVTVLAAVGKDAKPSDIVQPGHIFPLMAQEGGVLIRAGHTEAGCDLARLAGFEASSV
IVEILNDDGTMARRPDLEIFAQKHGLKMGTIADLIEYRNTKETSVVREAKCKLPTRFGEFDMLTYRDTIDNQLHHVLVKG
EVTENTLVRVHLQNTFNDLLHSERDQQRSWPLEKAMKRIGDEGGVLVLLGNHEHSSDILAKVKAFEAEDNGSTPVAAKWQ
GTSRQVGVGSQILADVGVTKMRLLSSPKRYHSLSGFGLEVTEYIAE

Specific function: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate [H]

COG id: COG0108

COG function: function code H; 3,4-dihydroxy-2-butanone 4-phosphate synthase

Gene ontology:

Cell location: Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the GTP cyclohydrolase II family [H]

Homologues:

Organism=Escherichia coli, GI1789420, Length=198, Percent_Identity=52.5252525252525, Blast_Score=215, Evalue=3e-57,
Organism=Escherichia coli, GI1787533, Length=166, Percent_Identity=29.5180722891566, Blast_Score=62, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6320695, Length=201, Percent_Identity=43.2835820895522, Blast_Score=170, Evalue=3e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR000422
- InterPro:   IPR000926
- InterPro:   IPR016299 [H]

Pfam domain/function: PF00926 DHBP_synthase; PF00925 GTP_cyclohydro2 [H]

EC number: =4.1.99.12 [H]

Molecular weight: Translated: 40284; Mature: 40153

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALHSIEEIIEDIRLGKMVILMDDEDRENEGDLIMAADMVTPEAVNFMATFGRGLICQTL
CCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCHHHHHH
TKARCQQLNLPLMVTNNNAQFSTNFTVSIEAAEGVTTGISAQDRAVTVLAAVGKDAKPSD
HHHHHHHCCCCEEEECCCCEEEEEEEEEEEECCCCCCCCCCCCCEEEEEEECCCCCCCCC
IVQPGHIFPLMAQEGGVLIRAGHTEAGCDLARLAGFEASSVIVEILNDDGTMARRPDLEI
CCCCCCEEEEEECCCCEEEEECCCCCCCCHHHHCCCCHHHEEEEEECCCCCCCCCCCHHH
FAQKHGLKMGTIADLIEYRNTKETSVVREAKCKLPTRFGEFDMLTYRDTIDNQLHHVLVK
HHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCEEEEEEHHHHHCCEEEEEEE
GEVTENTLVRVHLQNTFNDLLHSERDQQRSWPLEKAMKRIGDEGGVLVLLGNHEHSSDIL
CCCCCCEEEEEEEHHHHHHHHHCHHHHHHCCCHHHHHHHHCCCCCEEEEECCCCCCHHHH
AKVKAFEAEDNGSTPVAAKWQGTSRQVGVGSQILADVGVTKMRLLSSPKRYHSLSGFGLE
HHHHHEECCCCCCCCEEEEECCCCCCCCCCHHHHHHCCHHHHHHHCCCHHHHCCCCCCHH
VTEYIAE
HHHHHCC
>Mature Secondary Structure 
ALHSIEEIIEDIRLGKMVILMDDEDRENEGDLIMAADMVTPEAVNFMATFGRGLICQTL
CHHHHHHHHHHHCCCEEEEEECCCCCCCCCCEEEEECCCCHHHHHHHHHHCCCHHHHHH
TKARCQQLNLPLMVTNNNAQFSTNFTVSIEAAEGVTTGISAQDRAVTVLAAVGKDAKPSD
HHHHHHHCCCCEEEECCCCEEEEEEEEEEEECCCCCCCCCCCCCEEEEEEECCCCCCCCC
IVQPGHIFPLMAQEGGVLIRAGHTEAGCDLARLAGFEASSVIVEILNDDGTMARRPDLEI
CCCCCCEEEEEECCCCEEEEECCCCCCCCHHHHCCCCHHHEEEEEECCCCCCCCCCCHHH
FAQKHGLKMGTIADLIEYRNTKETSVVREAKCKLPTRFGEFDMLTYRDTIDNQLHHVLVK
HHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCEEEEEEHHHHHCCEEEEEEE
GEVTENTLVRVHLQNTFNDLLHSERDQQRSWPLEKAMKRIGDEGGVLVLLGNHEHSSDIL
CCCCCCEEEEEEEHHHHHHHHHCHHHHHHCCCHHHHHHHHCCCCCEEEEECCCCCCHHHH
AKVKAFEAEDNGSTPVAAKWQGTSRQVGVGSQILADVGVTKMRLLSSPKRYHSLSGFGLE
HHHHHEECCCCCCCCEEEEECCCCCCCCCCHHHHHHCCHHHHHHHCCCHHHHCCCCCCHH
VTEYIAE
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1339274 [H]