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The map label for this gene is ribE [H]

Identifier: 167623140

GI number: 167623140

Start: 1466213

End: 1466878

Strand: Direct

Name: ribE [H]

Synonym: Shal_1206

Alternate gene names: 167623140

Gene position: 1466213-1466878 (Clockwise)

Preceding gene: 167623139

Following gene: 167623141

Centisome position: 28.05

GC content: 48.5

Gene sequence:

>666_bases
ATGTTTACAGGGATTATTGAGTCTGTTGGCCACTTAAGAAAAGTAGAGCGCCGCGGTGATGATATTCGTTTAACGGTTGC
CAGTGGCAAGCTGGATCTGTCAGACGTAAAACTAGGCGACAGTATTGCCACCAATGGTGTGTGTTTGACCGTTGTTCAGT
TGATGGCCGACGGGTATGTGGCAGATATTTCAGCCGAAACTGTCAGTTTGACGGGTTTCTCTCATTATCCGGTGGGAAAA
GCCGTTAATCTTGAAAAAGCGGTTACCCCTACAACCCGTTTAGGCGGGCACATGGTTAGTGGTCACGTCGACGGTATTGC
TCATGTGGACGACAGGCAGTTTCGTGGCCAAGCGATTGAGTTTTGGTTAACACCGCCTGTTGAGCTGGGTCGTTATATCG
CCCATAAAGGCTCGATTACCATCGATGGCGTGAGTTTGACTGTCAATGAGGTGCAAGGCCATCGATTTAGACTGACCATA
GTACCGCACACTGCGGGCGAAACCACGTTAGTGGATCTGAAAGCCGGTGATAGCGTCAATATTGAAGTGGACTTAATCGC
CCGTCATTTAGAGAGACTAATGAGTTACCCCAGCCAAGAGCAAGATAATGGCCCCAAGTCTGAAGTGACCATGGAACTGT
TAGCACGCTCAGGTTTTTTACGATAA

Upstream 100 bases:

>100_bases
TGATTTTCAAGCCATGTCCGACATACCGCGTATCAACCTAATCGATGAGCGCAAAGTGGGTAAAGATACCCGCTTAACGT
TAAGAGTGAGTAATTAGTTT

Downstream 100 bases:

>100_bases
AGACTGGCTTAAGGCTAATTTGACGATTAAATTTGCCTTAATGACGCTTATAACAAGCAATAGAAACAAGAATAATCATT
ACATTAGCCACTATTTTTGA

Product: riboflavin synthase subunit alpha

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 221; Mature: 221

Protein sequence:

>221_residues
MFTGIIESVGHLRKVERRGDDIRLTVASGKLDLSDVKLGDSIATNGVCLTVVQLMADGYVADISAETVSLTGFSHYPVGK
AVNLEKAVTPTTRLGGHMVSGHVDGIAHVDDRQFRGQAIEFWLTPPVELGRYIAHKGSITIDGVSLTVNEVQGHRFRLTI
VPHTAGETTLVDLKAGDSVNIEVDLIARHLERLMSYPSQEQDNGPKSEVTMELLARSGFLR

Sequences:

>Translated_221_residues
MFTGIIESVGHLRKVERRGDDIRLTVASGKLDLSDVKLGDSIATNGVCLTVVQLMADGYVADISAETVSLTGFSHYPVGK
AVNLEKAVTPTTRLGGHMVSGHVDGIAHVDDRQFRGQAIEFWLTPPVELGRYIAHKGSITIDGVSLTVNEVQGHRFRLTI
VPHTAGETTLVDLKAGDSVNIEVDLIARHLERLMSYPSQEQDNGPKSEVTMELLARSGFLR
>Mature_221_residues
MFTGIIESVGHLRKVERRGDDIRLTVASGKLDLSDVKLGDSIATNGVCLTVVQLMADGYVADISAETVSLTGFSHYPVGK
AVNLEKAVTPTTRLGGHMVSGHVDGIAHVDDRQFRGQAIEFWLTPPVELGRYIAHKGSITIDGVSLTVNEVQGHRFRLTI
VPHTAGETTLVDLKAGDSVNIEVDLIARHLERLMSYPSQEQDNGPKSEVTMELLARSGFLR

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The alpha subunit catalyze

COG id: COG0307

COG function: function code H; Riboflavin synthase alpha chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 lumazine-binding repeats [H]

Homologues:

Organism=Escherichia coli, GI1787952, Length=185, Percent_Identity=35.1351351351351, Blast_Score=104, Evalue=4e-24,
Organism=Saccharomyces cerevisiae, GI6319733, Length=203, Percent_Identity=38.9162561576355, Blast_Score=134, Evalue=1e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001783
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00677 Lum_binding [H]

EC number: =2.5.1.9 [H]

Molecular weight: Translated: 23985; Mature: 23985

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTGIIESVGHLRKVERRGDDIRLTVASGKLDLSDVKLGDSIATNGVCLTVVQLMADGYV
CCCHHHHHHHHHHHHHHCCCEEEEEEECCCEEECCEECCCCCCCCCHHHHHHHHHHCCEE
ADISAETVSLTGFSHYPVGKAVNLEKAVTPTTRLGGHMVSGHVDGIAHVDDRQFRGQAIE
EECCCCEEEEECCCCCCCCCCCCCHHHCCCCHHCCCEEEECCCCCEEECCCCCCCCCEEE
FWLTPPVELGRYIAHKGSITIDGVSLTVNEVQGHRFRLTIVPHTAGETTLVDLKAGDSVN
EEECCHHHHHHHHHCCCCEEEEEEEEEEEECCCCEEEEEEEECCCCCEEEEEEECCCCEE
IEVDLIARHLERLMSYPSQEQDNGPKSEVTMELLARSGFLR
EEHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MFTGIIESVGHLRKVERRGDDIRLTVASGKLDLSDVKLGDSIATNGVCLTVVQLMADGYV
CCCHHHHHHHHHHHHHHCCCEEEEEEECCCEEECCEECCCCCCCCCHHHHHHHHHHCCEE
ADISAETVSLTGFSHYPVGKAVNLEKAVTPTTRLGGHMVSGHVDGIAHVDDRQFRGQAIE
EECCCCEEEEECCCCCCCCCCCCCHHHCCCCHHCCCEEEECCCCCEEECCCCCCCCCEEE
FWLTPPVELGRYIAHKGSITIDGVSLTVNEVQGHRFRLTIVPHTAGETTLVDLKAGDSVN
EEECCHHHHHHHHHCCCCEEEEEEEEEEEECCCCEEEEEEEECCCCCEEEEEEECCCCEE
IEVDLIARHLERLMSYPSQEQDNGPKSEVTMELLARSGFLR
EEHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8144477 [H]